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Estradiol - Generic Drug Details
What are the generic drug sources for estradiol and what is the scope of estradiol freedom to operate?
Estradiol
is the generic ingredient in thirty-nine branded drugs marketed by Allergan Sales Llc, Alvogen Pine Brook, Mylan Pharms Inc, Perrigo Uk Finco, Teva Pharms Usa, Bayer Hlthcare, Women First Hlthcare, Novartis, Mylan Technologies, Ortho Mcneil Pharm, Parke Davis, Noven, Mylan Speciality Lp, Ascend Theraps Us, Vertical Pharms Llc, Pharmacia And Upjohn, Therapeuticsmd Inc, Perrigo Pharma Intl, Bristol Myers Squibb, Barr Labs Inc, Epic Pharma Inc, Lannett Holdings Inc, Mayne Pharma, Mylan, Usl Pharma, Duramed Pharms Barr, Novo Nordisk Inc, Amneal Pharms, Glenmark Pharms Ltd, Millicent, Apil, Watson Labs, Exeltis Usa Inc, Par Sterile Products, Fosun Pharma, Luitpold, Watson Labs Inc, Savage Labs, Noven Pharms Inc, Amneal Pharms Llc, Lupin Ltd, Accord Hlthcare, Barr, Breckenridge Pharm, Mylan Labs Ltd, and Teva Womens, and is included in sixty-seven NDAs. There are sixteen patents protecting this compound and four Paragraph IV challenges. Additional information is available in the individual branded drug profile pages.There are seventy-five drug master file entries for estradiol. Forty-six suppliers are listed for this compound. There is one tentative approval for this compound.
Summary for estradiol
| US Patents: | 16 |
| Tradenames: | 39 |
| Applicants: | 46 |
| NDAs: | 67 |
| Drug Master File Entries: | 75 |
| Suppliers / Packagers: | 46 |
| Bulk Api Vendors: | 82 |
| Clinical Trials: | 739 |
| Patent Applications: | 7,050 |
| Formulation / Manufacturing: | see details |
| Drug Prices: | Drug price information for estradiol |
| Patent Litigation and PTAB cases: | See patent lawsuits and PTAB cases for estradiol |
| DailyMed Link: | estradiol at DailyMed |
Pharmacology for estradiol
| Ingredient-type | Estradiol Congeners |
| Drug Class | Estrogen |
| Mechanism of Action | Estrogen Receptor Agonists |
Medical Subject Heading (MeSH) Categories for estradiol
Synonyms for estradiol
| .alpha.-Oestradiol |
| .beta.-Estradiol |
| .beta.-Oestradiol |
| (+)-3,17.beta.-Estradiol |
| (+)-3,17b-Estradiol |
| (+)-3,17beta-Estradiol |
| (13S,17S)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-beta-diol |
| (17?)-Estra-1,3,5(10)-triene-3,17-diol |
| (17b)-Estra-1,3,5(10)-triene-3,17-diol |
| (17beta)-Estra-1,3,5(10)-triene-3,17-diol |
| (17beta)-estra-1(10),2,4-triene-3,17-diol |
| (1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2(7),3,5-triene-5,14-diol |
| (1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0;{2,7}.0;{11,15}]heptadeca-2,4,6-triene-5,14-diol |
| (1S,10R,11S,14S,15S)-15-METHYLTETRACYCLO[8.7.0.0(2),?.0(1)(1),(1)?]HEPTADECA-2,4,6-TRIENE-5,14-DIOL |
| (1S,10R,11S,14S,15S)-15-METHYLTETRACYCLO[8.7.0.0(2),?.0(1)(1),(1)?]HEPTADECA-2(7),3,5-TRIENE-5,14-DIOL |
| (1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0(2),.0(1)(1),(1)]heptadeca-2,4,6-triene-5,14-diol |
| (8''R'',9''S'',13''S'',14''S'',17''S'')-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[''a'']phenanthrene-3,17-diol |
| (8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol |
| (8R,9S,13S,14S,17S)-13-Methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol |
| (8S,9S,13S,14S,17S)-13-Methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol |
| [2,4,6,7-3H]-17beta-estradiol |
| [2,4,6,7-3H]-E2 |
| [3H]-estradiol |
| [3H]-Estrogen |
| [3H]]estradiol |
| [3H]17beta-estradiol |
| [3H]E2 |
| [3H]estradiol |
| 003E693 |
| 1,3,5-Estratriene-3,17-beta-diol |
| 1,3,5-Estratriene-3,17.beta.-diol |
| 1,3,5-Estratriene-3,17beta-diol |
| 1,3,5,(10)-Estratrien-3,17.beta.-diol |
| 1,3,5(10)-estratriene-3,17b-diol |
| 1,5-Estratriene-3,17.beta.-diol |
| 1050677-52-5 |
| 1206475-11-7 |
| 13b-Methyl-1,3,5(10)-gonatriene-3,17b-ol |
| 13beta-Methyl-1,3,5(10)-gonatriene-3,17beta-ol |
| 17 ?-Estradiol |
| 17 beta-Estradiol |
| 17-.BETA.-Estradiol |
| 17-beta |
| 17-beta-Estra-1,3,5(10)-triene-3,17-diol |
| 17-beta-estradiol |
| 17-beta-Estradiol hemihydrate 100 microg/mL in Acetonitrile |
| 17-beta-Oestra-1,3,5(10)-triene-3,17-diol |
| 17-beta-OH-estradiol |
| 17-beta-OH-oestradiol |
| 17-decahydrocyclopenta[a]phenanthrene-3,17-diol |
| 17-E |
| 17.beta.-Estra-1,3,5(10)-triene-3,17-diol |
| 17.beta.-Estra-1,5(10)-triene-3,17-diol |
| 17.beta.-Estradiol |
| 17.beta.-Oestra-1,3,5(10)-triene-3,17-diol |
| 17.beta.-Oestra-1,5(10)-triene-3,17-diol |
| 17.beta.-Oestradiol |
| 17.beta.-OH-estradiol |
| 17.beta.-OH-oestradiol |
| 17|A-estradiol;oestradiol;17|A-Oestradiol;|A-Estradiol |
| 17|A-Oestradiol |
| 17b-Estradiol |
| 17b-Oestradiol |
| 17beta estradiol (E2) |
| 17beta oestradiol |
| 17beta-Estra-1,3,5(10)-triene-3,17-diol |
| 17beta-Estradiol |
| 17beta-estradiol (E2) |
| 17beta-Estradiol solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material |
| 17beta-Oestra-1,3,5(10)-triene-3,17-diol |
| 17beta-Oestradiol |
| 1a52 |
| 1g50 |
| 1jgl |
| 1lhu |
| 1qkt |
| 1qku |
| 2d06 |
| 2j7x |
| 3,17-.beta.-Oestradiol |
| 3,17-beta-Dihydroxy-1,3,5(10)-oestratriene |
| 3,17-beta-Dihydroxyestra-1,3,5(10)-triene |
| 3,17-beta-Dihydroxyoestra-1,3,5-triene |
| 3,17-beta-Estradiol |
| 3,17-beta-Oestradiol |
| 3,17-dihydroxy-delta(1,3,5-10)-estratriene |
| 3,17-Epidihydroxyestratriene |
| 3,17-Epidihydroxyoestratriene |
| 3,17.beta.-Dihydroxy-1,3,5(10)-estratriene |
| 3,17.beta.-Dihydroxy-1,3,5(10)-oestratriene |
| 3,17.beta.-Dihydroxyestra-1,3,5-triene |
| 3,17.beta.-Dihydroxyestra-1,3,5(10)-triene |
| 3,17.beta.-Dihydroxyoestra-1,3,5-triene |
| 3,17.beta.-Estradiol |
| 3,17b-Dihydroxyestra-1,3,5(10)-triene |
| 3,17b-Estradiol |
| 3,17beta-Dihydroxy-1,3,5(10)-estratriene |
| 3,17beta-Dihydroxyestra-1,3,5-triene |
| 3,17beta-dihydroxyestra-1,3,5(10)-trien |
| 3,17beta-Dihydroxyestra-1,3,5(10)-triene |
| 3,17beta-Dihydroxyoestra-1,3,5-triene |
| 3,17beta-Estradiol |
| 3,3,5-triene |
| 3,3,5(10)-triene |
| 4TI98Z838E |
| 50-28-2 |
| 73459-61-7 |
| 873662-39-6 |
| AB0012866 |
| AB2000237 |
| AC-22346 |
| AC1L1L2K |
| ACN-S003579 |
| Activella (Salt/Mix) |
| Activella (TN) |
| Aerodiol |
| AJ-64042 |
| AK167943 |
| AKOS015896570 |
| Alora |
| Alora (TN) |
| alpha-estradiol (obsolete) |
| alpha-Oestradiol |
| Altrad |
| Amnestrogen |
| AN-6628 |
| Angeliq (TN) |
| AOB5963 |
| Aquadiol |
| AS-13729 |
| B-Estradiol |
| B8B5AEF5-4957-49EB-A14F-444A8212C482 |
| Bardiol |
| BC200811 |
| BDBM17292 |
| Benzogynestry |
| beta-Estradiol |
| beta-Estradiol, >=98% |
| beta-Estradiol, analytical standard |
| beta-Estradiol, BioReagent, powder, suitable for cell culture |
| beta-Estradiol, powder, gamma-irradiated, BioXtra, suitable for cell culture |
| beta-Oestradiol |
| BIDD:ER0125 |
| BIDD:PXR0065 |
| Bio-0812 |
| Bio-E-Gel |
| Bio1_000403 |
| Bio1_000892 |
| Bio1_001381 |
| Bio2_000363 |
| Bio2_000843 |
| bmse000642 |
| BPBio1_000532 |
| BRD-K18910433-001-04-4 |
| BSPBio_000482 |
| BSPBio_001065 |
| BT000387 |
| C00951 |
| C18H24O2 |
| CAS-50-28-2 |
| CCG-100808 |
| CCRIS 280 |
| CHEBI:16469 |
| CHEMBL135 |
| cis-Estradiol |
| cis-Oestradiol |
| Climaderm |
| Climara |
| Climara (TN) |
| Climara Forte |
| Climara Pro (Salt/Mix) |
| Climara, Menostar |
| cMAP_000005 |
| CMC_11154 |
| Combipatch (Salt/Mix) |
| component of Menrium |
| Compudose |
| Compudose 200 |
| Compudose 365 |
| Corpagen |
| CPD000059126 |
| CS-1938 |
| D-3,17-beta-Estradiol |
| D-3,17-beta-Oestradiol |
| D-3,17.beta.-Estradiol |
| D-3,17.beta.-Oestradiol |
| D-3,17beta-Estradiol |
| D-3,17beta-Oestradiol |
| D-Estradiol |
| D-Oestradiol |
| D00105 |
| D08QMX |
| DB00783 |
| delta-Estradiol |
| delta-Oestradiol |
| Dermestril |
| Destradiol |
| dihydro-Theelin |
| Dihydrofollicular hormone |
| Dihydrofolliculin |
| Dihydromenformon |
| Dihydrotheelin |
| Dihydroxyesterin |
| Dihydroxyestrin |
| Dihydroxyoestrin |
| Dimenformon |
| Dimenformon prolongatum |
| Diogyn |
| Diogynets |
| Divigel |
| Divigel (TN) |
| DSSTox_CID_573 |
| DSSTox_GSID_20573 |
| DSSTox_RID_75666 |
| DTXSID0020573 |
| E 2 |
| E 8875 |
| E(sub 2) |
| E0025 |
| EC 200-023-8 |
| EINECS 200-023-8 |
| Elestrim |
| Elestrin |
| Elestrin (TN) |
| Encore |
| Epiestriol 50 |
| Epitope ID:136018 |
| Esclim |
| Estasorb |
| Estra-1,3,5(10)-triene -3,17beta-diol |
| Estra-1,3,5(10)-triene-3,17-beta-diol |
| Estra-1,3,5(10)-triene-3,17-diol (17.beta.)- |
| Estra-1,3,5(10)-triene-3,17-diol (17beta)- |
| Estra-1,3,5(10)-triene-3,17-diol (17beta)-, homopolymer |
| Estra-1,3,5(10)-triene-3,17-diol, (17beta)- |
| Estra-1,3,5(10)-triene-3,17-diol(17b)- |
| Estra-1,3,5(10)-triene-3,17.beta.-diol |
| Estra-1,3,5(10)-triene-3,17b-diol |
| Estra-1,3,5(10)-triene-3,17beta-diol |
| Estra-1,5(10)-triene-3,17-diol (17.beta.)- |
| Estra-1,5(10)-triene-3,17-diol, (17.beta.)- |
| Estra-1,5(10)-triene-3,17.beta.-diol |
| estra-1(10),2,4-triene-3,17-diol, (17beta)- |
| Estrace |
| Estrace (TN) |
| Estraderm |
| Estraderm (TN) |
| Estraderm MX |
| Estraderm TTS |
| Estraderm TTS (TN) |
| Estraderm TTS 100 |
| Estraderm TTS 50 |
| Estradiol - Acrux |
| Estradiol (JAN/USP/INN) |
| Estradiol [USAN:INN] |
| Estradiol [USP:INN:BAN] |
| Estradiol acetate (TN) |
| Estradiol complex |
| Estradiol cypionate (TN) |
| ESTRADIOL HEMIHYDRATE |
| Estradiol valerate (TN) |
| Estradiol-17 alpha |
| Estradiol-17 beta |
| Estradiol-17-beta |
| Estradiol-17.beta. |
| estradiol-17beta |
| Estradiol-3,17beta |
| Estradiol, .beta.- |
| Estradiol, meets USP testing specifications |
| Estradiol, pharmaceutical secondary standard; traceable to USP, PhEur and BP |
| Estradiol, United States Pharmacopeia (USP) Reference Standard |
| Estradiolo |
| Estradiolo [DCIT] |
| Estradiolum |
| Estradiolum [INN] |
| Estradot |
| Estraldine |
| Estrapak 50 |
| Estrasorb |
| Estrasorb (TN) |
| Estrasorb Topical (TN) |
| Estreva |
| Estrifam |
| Estring |
| Estring (TN) |
| Estring vaginal ring |
| Estroclim |
| Estroclim 50 |
| Estrodiolum |
| Estrodiolum [INN-Latin] |
| Estrofem (TN) |
| Estrofem 2 |
| Estrofem Forte |
| Estrogel |
| Estrogel (TN) |
| Estrogel HBF |
| Estrogens, esterified |
| Estropause |
| Estrovite |
| EU-0100503 |
| Evamist |
| EvaMist (TN) |
| Evorel |
| Extrasorb |
| Fem7 |
| Femanest |
| Femestral |
| Femestrol |
| Femogen |
| Fempatch |
| Femtran |
| Follicyclin |
| Gelestra |
| Ginedisc |
| Ginosedol |
| GTPL1012 |
| GTPL1013 |
| Gynergon |
| Gynestrel |
| Gynodiol |
| Gynoestryl |
| GynPolar |
| HMS1362E07 |
| HMS1569I04 |
| HMS1792E07 |
| HMS1990E07 |
| HMS2051C17 |
| HMS2090E18 |
| HMS2096I04 |
| HMS2236H04 |
| HMS3261F07 |
| HMS3403E07 |
| HSDB 3589 |
| HY-B0141 |
| I06-2405 |
| IDI1_002118 |
| Innofem |
| Innofem (TN) |
| J10189 |
| KBio2_000405 |
| KBio2_002269 |
| KBio2_002973 |
| KBio2_004837 |
| KBio2_005541 |
| KBio2_007405 |
| KBio3_000769 |
| KBio3_000770 |
| KBio3_002749 |
| KBioGR_000405 |
| KBioGR_002269 |
| KBioSS_000405 |
| KBioSS_002270 |
| Lamdiol |
| LMST02010001 |
| Lopac0_000503 |
| LP00503 |
| LS-137 |
| Macrodiol |
| Macrol |
| Menest |
| Menorest |
| Menostar (TN) |
| MFCD00003693 |
| Microdiol |
| Minivelle |
| MLS000069494 |
| MLS000758312 |
| MLS001076331 |
| MLS001424022 |
| MolPort-001-794-632 |
| NC00058 |
| NCGC00091544-00 |
| NCGC00091544-01 |
| NCGC00091544-02 |
| NCGC00091544-04 |
| NCGC00091544-05 |
| NCGC00091544-06 |
| NCGC00091544-07 |
| NCGC00091544-09 |
| NCGC00091544-10 |
| NCGC00091544-11 |
| NCGC00091544-12 |
| NCGC00091544-13 |
| NCGC00091544-14 |
| NCGC00091544-15 |
| NCGC00091544-16 |
| NCGC00179321-01 |
| NCGC00179321-02 |
| NCGC00254177-01 |
| NCGC00259606-01 |
| NCGC00261188-01 |
| Nordicol |
| NSC-9895 |
| NSC9895 |
| Oesclim |
| Oestergon |
| Oestra-1,3,5(10)-triene-3,17-beta-diol |
| Oestra-1,3,5(10)-triene-3,17.beta.-diol |
| Oestra-1,3,5(10)-triene-3,17b-diol |
| Oestra-1,3,5(10)-triene-3,17beta-diol |
| Oestra-1,5(10)-triene-3,17.beta.-diol |
| Oestradiol |
| Oestradiol Berco |
| Oestradiol R |
| Oestradiol-17-beta |
| Oestradiol-17.beta. |
| Oestradiol-17beta |
| Oestradiol-17beta and esters |
| Oestradiol-17beta and esters [Steroidal oestrogens] |
| Oestradiolum |
| oestrodiol |
| Oestrogel |
| Oestroglandol |
| Oestrogynal |
| Opera_ID_1688 |
| Ovahormon |
| Ovasterol |
| Ovastevol |
| Ovociclina |
| Ovocyclin |
| Ovocycline |
| Ovocylin |
| Perlatanol |
| PL004792 |
| PL057607 |
| Polyestradiol |
| Prestwick_207 |
| Prestwick0_000441 |
| Prestwick1_000441 |
| Prestwick2_000441 |
| Prestwick3_000441 |
| Primofol |
| Profoliol |
| Profoliol B |
| progynon |
| Progynon DH |
| Progynon-DH |
| Progynova (TN) |
| Q-201503 |
| S-21400 |
| s1709 |
| Sandrena 1 |
| Sandrena Gel |
| SC-25771 |
| SCHEMBL8049 |
| Sisare Gel |
| SK-Estrogens |
| SL-1100 |
| SMP1_000121 |
| SMR000059126 |
| SPBio_002421 |
| Spectrum5_002055 |
| SR-01000075866 |
| SR-01000075866-4 |
| SY017569 |
| Syndiol |
| Systen |
| Theelin, dihydro- |
| Tox21_111148 |
| Tox21_202057 |
| Tox21_300288 |
| Tox21_500503 |
| Tradelia |
| Trial SAT |
| Trocosone |
| TX-004HR |
| UNII-4TI98Z838E |
| Vagifem |
| Vagifem (TN) |
| Vivelle |
| Vivelle (TN) |
| VIVELLE-DOT |
| Vivelle-Dot (TN) |
| VOXZDWNPVJITMN-ZBRFXRBCSA-N |
| WLN: L E5 B666TTT&J E1 FQ OQ |
| Yuvvexy |
| Z-4415 |
| Z1847670481 |
| Zerella |
| Zesteem |
| Zesteen |
| ZINC13520815 |
| Zumenon |
Tentative approvals for ESTRADIOL
| Applicant | Application No. | Strength | Dosage Form |
| ➤ Try a Free Trial | ➤ Try a Free Trial | 3MG;2MG;3MG | TABLET;ORAL |
| ➤ Try a Free Trial | ➤ Try a Free Trial | 1MG;2MG;2MG | TABLET;ORAL |
US Patents and Regulatory Information for estradiol
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Exclusivity Expiration |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mylan Technologies | ESTRADIOL | estradiol | FILM, EXTENDED RELEASE;TRANSDERMAL | 075182-005 | Jul 20, 2006 | AB | RX | No | No | ➤ Try a Free Trial | ➤ Try a Free Trial | ➤ Try a Free Trial | |||
| Glenmark Pharms Ltd | ESTRADIOL | estradiol | TABLET;VAGINAL | 210264-001 | Sep 14, 2018 | AB | RX | No | No | ➤ Try a Free Trial | ➤ Try a Free Trial | ➤ Try a Free Trial | |||
| Mylan Technologies | ESTRADIOL | estradiol | FILM, EXTENDED RELEASE;TRANSDERMAL | 075182-006 | Feb 24, 2000 | AB2 | RX | No | No | ➤ Try a Free Trial | ➤ Try a Free Trial | ➤ Try a Free Trial | |||
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Exclusivity Expiration |
Expired US Patents for estradiol
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | Patent No. | Patent Expiration |
|---|---|---|---|---|---|---|---|
| Bayer Hlthcare | CLIMARA | estradiol | FILM, EXTENDED RELEASE;TRANSDERMAL | 020375-001 | Dec 22, 1994 | ➤ Try a Free Trial | ➤ Try a Free Trial |
| Novartis | VIVELLE-DOT | estradiol | FILM, EXTENDED RELEASE;TRANSDERMAL | 020538-008 | Jan 8, 1999 | ➤ Try a Free Trial | ➤ Try a Free Trial |
| Novartis | VIVELLE | estradiol | FILM, EXTENDED RELEASE;TRANSDERMAL | 020323-003 | Oct 28, 1994 | ➤ Try a Free Trial | ➤ Try a Free Trial |
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | Patent No. | Patent Expiration |
International Patents for estradiol
| Country | Document Number | Estimated Expiration |
|---|---|---|
| World Intellectual Property Organization (WIPO) | 0243611 | ➤ Try a Free Trial |
| European Patent Office | 3122364 | ➤ Try a Free Trial |
| European Patent Office | 2861072 | ➤ Try a Free Trial |
| Country | Document Number | Estimated Expiration |
Supplementary Protection Certificates for estradiol
| Supplementary Protection Certificate | SPC Country | SPC Expiration | SPC Description |
|---|---|---|---|
| 2009 00017 | Denmark | ➤ Try a Free Trial | PRODUCT NAME: ETHINYLESTRADIOL (SOM BETADEXCLATHRAT) OG DROSPIRENON; NAT. REG. NO/DATE: 42417 (DK) 20080619; FIRST REG. NO/DATE: NL 33842 20070629 |
| C/GB04/032 | United Kingdom | ➤ Try a Free Trial | PRODUCT NAME: ESTRADIOL, OPTIONALLY IN THE FORM OF A HYDRATE, TOGETHER WITH DROSPIRENONE; REGISTERED: NL RVG 27505 20021211; UK PL 00053/0341 20040310 |
| 2006 00038 | Denmark | ➤ Try a Free Trial | PRODUCT NAME: ETHINYLESTRADIOL (SOM BETA-CYCLODEXTRIN-CLATHRAT) OG DROSPIRENON; NAT. REG. NO/DATE: 38687 20060627; FIRST REG. NO/DATE: EU RVG 31781 20050804 |
| Supplementary Protection Certificate | SPC Country | SPC Expiration | SPC Description |
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Major Patent Expirations 2018 - 2019
ISSN: 2162-2639
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Major Patent Expirations 2018 - 2019
Preferred Citation:
Friedman, Yali. "DrugPatentWatch" DrugPatentWatch, thinkBiotech, 2018, www.DrugPatentWatch.com.
Friedman, Yali. "DrugPatentWatch" DrugPatentWatch, thinkBiotech, 2018, www.DrugPatentWatch.com.
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