France: These 7 Drugs Face Patent Expirations and Generic Entry in 2026 - 2027
DrugPatentWatch® Estimated Loss of Exclusivity Dates in France
Generic Entry Dates in Other Countries
These estimated drug patent expiration dates and generic entry opportunity dates are calculated from analysis of known patents covering drugs. Many factors can influence early or late generic entry. This information is provided as a rough estimate of generic entry potential and should not be used as an independent source. The methodology is described in this blog post.
Summary: France: These 7 Drugs Face Patent Expirations and Generic Entry in 2026 - 2027
| Tradename | Ingredient | Estimated Entry Opportunity Date |
|---|---|---|
| EPIDUO | adapalene; benzoyl peroxide | 2026-07-13 |
| EPIDUO FORTE | adapalene; benzoyl peroxide | 2026-07-13 |
| KORSUVA | difelikefalin acetate | 2026-11-10 |
| TEPMETKO | tepotinib hydrochloride | 2027-07-12 |
| OPSUMIT | macitentan | 2026-08-29 |
| WINLEVI | clascoterone | 2027-08-03 |
| >Tradename | >Ingredient | >Estimated Entry Opportunity Date |
Details: France: These 7 Drugs Face Patent Expirations and Generic Entry in 2026 - 2027
When can EPIDUO (adapalene; benzoyl peroxide) generic drug versions launch?
Generic name: adapalene; benzoyl peroxide
DrugPatentWatch® Estimated Patent Expiration / Generic Entry Opportunity Date: July 13, 2026
Generic Entry Controlled by: France Patent 2,903,603

This drug has thirty-five patent family members in twenty-two countries. There has been litigation on patents covering EPIDUO
See drug price trends for EPIDUO.
The generic ingredient in EPIDUO is adapalene; benzoyl peroxide. There are twelve drug master file entries for this API. Twelve suppliers are listed for this generic product. Additional details are available on the adapalene; benzoyl peroxide profile page.
When can EPIDUO FORTE (adapalene; benzoyl peroxide) generic drug versions launch?
Generic name: adapalene; benzoyl peroxide
DrugPatentWatch® Estimated Patent Expiration / Generic Entry Opportunity Date: July 13, 2026
Generic Entry Controlled by: France Patent 2,903,603

See drug price trends for EPIDUO FORTE.
The generic ingredient in EPIDUO FORTE is adapalene; benzoyl peroxide. There are twelve drug master file entries for this API. Twelve suppliers are listed for this generic product. Additional details are available on the adapalene; benzoyl peroxide profile page.
When can KORSUVA (difelikefalin acetate) generic drug versions launch?
Generic name: difelikefalin acetate
DrugPatentWatch® Estimated Patent Expiration / Generic Entry Opportunity Date: November 10, 2026
Generic Entry Controlled by: France Patent 22C1054
KORSUVA is a drug marketed by Vifor Intl. There are twelve patents protecting this drug.
This drug has fifty-three patent family members in twenty-seven countries. There has been litigation on patents covering KORSUVA
See drug price trends for KORSUVA.
The generic ingredient in KORSUVA is difelikefalin acetate. One supplier is listed for this generic product. Additional details are available on the difelikefalin acetate profile page.
When can TEPMETKO (tepotinib hydrochloride) generic drug versions launch?
Generic name: tepotinib hydrochloride
DrugPatentWatch® Estimated Patent Expiration / Generic Entry Opportunity Date: July 12, 2027
Generic Entry Controlled by: France Patent 22C1024
TEPMETKO is a drug marketed by Emd Serono Inc. There are eight patents protecting this drug.
This drug has seventy-nine patent family members in thirty-six countries. There has been litigation on patents covering TEPMETKO
See drug price trends for TEPMETKO.
The generic ingredient in TEPMETKO is tepotinib hydrochloride. One supplier is listed for this generic product. Additional details are available on the tepotinib hydrochloride profile page.
When can OPSUMIT (macitentan) generic drug versions launch?
Generic name: macitentan
DrugPatentWatch® Estimated Patent Expiration / Generic Entry Opportunity Date: August 29, 2026
Generic Entry Controlled by: France Patent 24C1054
OPSUMIT is a drug marketed by Actelion. There are five patents protecting this drug and one Paragraph IV challenge. One tentatively approved generic is ready to enter the market.
This drug has one hundred and one patent family members in thirty-five countries. There has been litigation on patents covering OPSUMIT
See drug price trends for OPSUMIT.
The generic ingredient in OPSUMIT is macitentan. There are ten drug master file entries for this API. One supplier is listed for this generic product. Additional details are available on the macitentan profile page.
When can WINLEVI (clascoterone) generic drug versions launch?
Generic name: clascoterone
DrugPatentWatch® Estimated Patent Expiration / Generic Entry Opportunity Date: August 03, 2027
Generic Entry Controlled by: France Patent 25C1053

This drug has ninety-three patent family members in twenty-nine countries. There has been litigation on patents covering WINLEVI
See drug price trends for WINLEVI.
The generic ingredient in WINLEVI is clascoterone. One supplier is listed for this generic product. Additional details are available on the clascoterone profile page.
When can ZYKADIA (ceritinib) generic drug versions launch?
Generic name: ceritinib
DrugPatentWatch® Estimated Patent Expiration / Generic Entry Opportunity Date: December 08, 2026
Generic Entry Controlled by: France Patent 15C0058
ZYKADIA is a drug marketed by Novartis. There are eight patents protecting this drug.
This drug has three hundred and twenty-two patent family members in fifty-six countries.
See drug price trends for ZYKADIA.
The generic ingredient in ZYKADIA is ceritinib. There is one drug master file entry for this API. One supplier is listed for this generic product. Additional details are available on the ceritinib profile page.
When can MULPLETA (lusutrombopag) generic drug versions launch?
Generic name: lusutrombopag
DrugPatentWatch® Estimated Patent Expiration / Generic Entry Opportunity Date: July 31, 2027
Generic Entry Controlled by: France Patent 19C1043
MULPLETA is a drug marketed by Vancocin Italia. There are three patents protecting this drug.
This drug has forty-one patent family members in twenty countries.
See drug price trends for MULPLETA.
The generic ingredient in MULPLETA is lusutrombopag. Three suppliers are listed for this generic product. Additional details are available on the lusutrombopag profile page.
When can EVOTAZ (atazanavir sulfate; cobicistat) generic drug versions launch?
Generic name: atazanavir sulfate; cobicistat
DrugPatentWatch® Estimated Patent Expiration / Generic Entry Opportunity Date: July 07, 2026
Generic Entry Controlled by: France Patent 15C0078

This drug has three hundred and six patent family members in forty-one countries. There has been litigation on patents covering EVOTAZ
See drug price trends for EVOTAZ.
The generic ingredient in EVOTAZ is atazanavir sulfate; cobicistat. There are twenty-five drug master file entries for this API. One supplier is listed for this generic product. Additional details are available on the atazanavir sulfate; cobicistat profile page.
When can EVOTAZ (atazanavir sulfate; cobicistat) generic drug versions launch?
Generic name: atazanavir sulfate; cobicistat
DrugPatentWatch® Estimated Patent Expiration / Generic Entry Opportunity Date: July 07, 2026
Generic Entry Controlled by: France Patent 17C1000

This drug has three hundred and six patent family members in forty-one countries. There has been litigation on patents covering EVOTAZ
See drug price trends for EVOTAZ.
The generic ingredient in EVOTAZ is atazanavir sulfate; cobicistat. There are twenty-five drug master file entries for this API. One supplier is listed for this generic product. Additional details are available on the atazanavir sulfate; cobicistat profile page.
When can EVOTAZ (atazanavir sulfate; cobicistat) generic drug versions launch?
Generic name: atazanavir sulfate; cobicistat
DrugPatentWatch® Estimated Patent Expiration / Generic Entry Opportunity Date: July 07, 2026
Generic Entry Controlled by: France Patent 17C1001

This drug has three hundred and six patent family members in forty-one countries. There has been litigation on patents covering EVOTAZ
See drug price trends for EVOTAZ.
The generic ingredient in EVOTAZ is atazanavir sulfate; cobicistat. There are twenty-five drug master file entries for this API. One supplier is listed for this generic product. Additional details are available on the atazanavir sulfate; cobicistat profile page.
When can EVOTAZ (atazanavir sulfate; cobicistat) generic drug versions launch?
Generic name: atazanavir sulfate; cobicistat
DrugPatentWatch® Estimated Patent Expiration / Generic Entry Opportunity Date: July 07, 2026
Generic Entry Controlled by: France Patent 17C1002

This drug has three hundred and six patent family members in forty-one countries. There has been litigation on patents covering EVOTAZ
See drug price trends for EVOTAZ.
The generic ingredient in EVOTAZ is atazanavir sulfate; cobicistat. There are twenty-five drug master file entries for this API. One supplier is listed for this generic product. Additional details are available on the atazanavir sulfate; cobicistat profile page.
When can EVOTAZ (atazanavir sulfate; cobicistat) generic drug versions launch?
Generic name: atazanavir sulfate; cobicistat
DrugPatentWatch® Estimated Patent Expiration / Generic Entry Opportunity Date: July 07, 2026
Generic Entry Controlled by: France Patent 20C1021

This drug has three hundred and six patent family members in forty-one countries. There has been litigation on patents covering EVOTAZ
See drug price trends for EVOTAZ.
The generic ingredient in EVOTAZ is atazanavir sulfate; cobicistat. There are twenty-five drug master file entries for this API. One supplier is listed for this generic product. Additional details are available on the atazanavir sulfate; cobicistat profile page.
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