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DOXYCYCLINE HYCLATE - Generic Drug Details
What are the generic drug sources for doxycycline hyclate and what is the scope of doxycycline hyclate patent protection?
Doxycycline hyclate has two patent family members in two countries.
There are twenty-seven drug master file entries for doxycycline hyclate. Ninety-five suppliers are listed for this compound.
Summary for DOXYCYCLINE HYCLATE
International Patents: | 2 |
US Patents: | 5 |
Tradenames: | 14 |
Applicants: | 47 |
NDAs: | 71 |
Drug Master File Entries: | 27 |
Suppliers / Packagers: | 95 |
Bulk Api Vendors: | 108 |
Clinical Trials: | 219 |
Patent Applications: | 3,083 |
Formulation / Manufacturing: | see details |
Drug Prices: | see low prices |
DailyMed Link: | DOXYCYCLINE HYCLATE at DailyMed |
Pharmacology for DOXYCYCLINE HYCLATE
Ingredient-type | Tetracyclines |
Drug Class | Tetracycline-class Drug |
Synonyms for DOXYCYCLINE HYCLATE
(1S,4aS,11R,11aR,12S,12aR)-3-carbamoyl-2,4a,5,7,12-pentahydroxy-N,N,11-trimethyl-4,6-dioxo-1,4,4a,6,11,11a,12,12a-octahydrotetracen-1-aminium chloride--ethanol--water (2/1/1) |
(2E,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione |
(2E,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione; ethanol; hydrate; dihydrochloride |
(2Z,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione; ethanol; hydrate; dihydrochloride |
(2Z,4S,4AR,5S,5AR,6R,12AS)-2-[AMINO(HYDROXY)METHYLIDENE]-4-(DIMETHYLAMINO)-5,10,11,12A-TETRAHYDROXY-6-METHYL-1,2,3,4,4A,5,5A,6,12,12A-DECAHYDROTETRACENE-1,3,12-TRIONE |
(2Z,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione |
(2Z,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione hydrochloride |
(2Z,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione; ethanol; hydrate; dihydrochloride |
(2Z,4S,4aR,5S,5aR,6R)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione |
(2Z)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione |
(4S,4aR,5S,5aR,6R,12aR)-4-(dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide |
(4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione |
(4S,4aR,5S,5aR,6R,12aS)-4-(Dimethylamino)- 3,5,10,12,12a-pentahydroxy- 6-methyl- 1,11-dioxo- 1,4,4a,5,5a,6,11,12a-octahydrotetracene- 2-carboxamide hydrochloride hemiethanolate hemihydrate |
(4s,4ar,5s,5ar,6r,12as)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide |
(4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide |
(4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide - ethanol (2:1) dihydrochloride hydrate |
(4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide compound with ethanol (2:1) dihydrochloride hydrate |
(4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide |
(4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide;ethanol;hydrate;dihydrochloride |
100929-47-3 |
10592-13-9 |
10592-13-9 (. HCl) |
10597-92-9 |
1368-EP2269978A2 |
1368-EP2269985A2 |
1368-EP2269991A2 |
1368-EP2284150A2 |
1368-EP2284151A2 |
1368-EP2284152A2 |
1368-EP2284153A2 |
1368-EP2284155A2 |
1368-EP2284156A2 |
1368-EP2284164A2 |
1368-EP2287140A2 |
1368-EP2287148A2 |
1368-EP2287150A2 |
1368-EP2289871A1 |
1368-EP2295402A2 |
1368-EP2295419A2 |
1368-EP2298732A1 |
1368-EP2301534A1 |
1368-EP2301912A2 |
1368-EP2301913A1 |
1368-EP2301914A1 |
1368-EP2301916A2 |
1368-EP2305637A2 |
1368-EP2305640A2 |
1368-EP2308863A1 |
1368-EP2311451A1 |
1368-EP2311796A1 |
1368-EP2311797A1 |
1368-EP2311798A1 |
1368-EP2311799A1 |
1368-EP2316450A1 |
17086-28-1 (mono-hydrate) |
19XTS3T51U |
2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a, 5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy -6-methyl-1,11-dioxo-, monohydrochloride, (4S,4aR,5S,5aR,6R,12aS)-, compd. with ethanol (2:1), mono |
2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S-(4alpha,4aalpha,5alpha,5aalpha,6alpha,12aalpha))- |
2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S,4aR,5S,5aR,6R,12aS) |
2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S,4aR,5S,5aR,6R,12aS)- |
2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride, (4S,4aR,5S,5aR,6R,12aS)-, compd. with ethanol, hydrate (2:2:1:1) |
2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, (4S-(4alpha,4aalpha,5alpha,5aalpha,6alpha,12aalpha))- |
2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, (4S,4aR,5S,5aR,6R,12aS)- |
2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, compd. with ethanol (2:1), monohydrate, (4S-(4alpha,4aalpha,5alpha,5aalpha,6alpha, |
2-Naphthacenecarboxamide, 4-alpha-S-(dimethylamino)-1,4,4a-alpha-5,5a-alpha,6,11,12a-octahydro-3,5-alpha,10,12,12a-alpha-pentahydroxy-6-alpha-methyl-1,11-dioxo- |
2-Naphthacenecarboxamide, 4-dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride |
2-Naphthacenecarboxamide, 4beta-(dimeethylamino)-1,4,4abeta,5,5abeta,6,11,12a-octahydro-3,5beta,10,12,12abeta-pentahydroxy-6beta-methyl-1,11-dioxo-, monohydrochloride, compd. with ethyl alcohol (2:1), monohydrate |
2-Naphthacenecarboxamide,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, (4S,4aR,5S,5aR,6R,12aS)-, compd. with ethanol (2:1), monohydrate (9CI) (CA INDEX NAME) |
2387AH |
24390-14-5 |
2C22H24N2O8.C2H6O.2ClH.H2O |
2C22H24N2O8.C2H6O.H2O |
334895S862 |
390D145 |
4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide monohydrochloride, compound with ethyl alcohol (2:1), monohydrate |
4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide - ethanol (2:1) dihydrochloride hydrate |
4-Epioxytetracycline, 6-deoxy- |
41411-66-9 (6-epimer, mono-hydrochloride) |
4182Z6T2ET |
5-Hydroxy-alpha-6-deoxytetracycline |
5-Hydroxy-alpha-6-deoxytetracycline monohydrate |
53108-42-2 |
564-25-0 |
564D250 |
6-alpha-Deoxy-5-oxytetracycline |
6-Deoxy-5-hydroxytetracycline hydrochloride hemihydrate |
6-Deoxyoxytetracycline |
6-Deoxytetracycline |
6-Desoxy-5-hydroxytetracycline hydrochloride hemihydrate hemiethanolate |
61281-03-6 |
62149-53-5 |
69935-17-7 (mono-hydrochloride, di-hydrate) |
6alpha-Deoxy-5-oxytetracycline |
7164-70-7 |
7264-10-0 |
94088-85-4 (calcium salt (1:2)) |
AB00053465_04 |
AB00053465_05 |
AB00053465-03 |
AB08 (*Fosfatex) |
AC-12044 |
AC-6017 |
AC1L1WYQ |
AC1NQXW7 |
AC1NQZPV |
AC1NTTH2 |
AC1NUYS5 |
AC1NUYS8 |
Acticlate |
Acticlate CAP |
AK321970 |
AK322076 |
AKOS015900372 |
AKOS015924649 |
AKOS025310153 |
AKOS025402170 |
alpha-6-Deoxy-5-hydroxytetracycline |
alpha-6-Deoxyoxytetracycline |
alpha-6-Deoxyoxytetracycline monohydrate |
alpha-6-Tetracycline monohydrate |
alpha-Doxycycline |
Alti-Doxycycline |
Ambap100929-47-3 |
AN-18097 |
Anhydrous doxycycline |
API0002491 |
API0002492 |
Apo-Doxy |
AS-13499 |
Atridox |
Azudoxat |
BCBcMAP01_000024 |
Biocamycin |
bis((4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide) ethanol hydrate dihydrochloride |
BMY 28689 |
BMY-28689 |
BMY28689 |
BSPBio_001936 |
BU 3839T |
BU-3839T |
C-0055 |
C06973 |
C22H24N2O8.HCl.0.5H2O.0.5C2H6O |
C22H25ClN2O8 |
CAS-10592-13-9 |
CCG-204498 |
CCG-38949 |
CHEBI:34730 |
CHEBI:50845 |
CHEBI:652992 |
CHEMBL1200567 |
CHEMBL1256723 |
CHEMBL1433 |
CHEMBL436921 |
CS-2632 |
D 9891 |
D02129 |
D07876 |
D07877 |
D0S0LZ |
D4116 |
DB00254 |
Dentista |
Deoxy-5-hydroxytetracycline hydrochloride |
Deoxymykoin |
Deoxyoxytetracycline hydrochloride |
DivK1c_000345 |
DMSC (*Fosfatex) |
Doryx |
Doryx (TN) |
Doryx Mpc |
Dossiciclina |
Dossiciclina [DCIT] |
DOXCYCLINE ANHYDROUS |
Doxiciclina |
Doxiciclina [INN-Spanish] |
Doxiciclina [Italian] |
Doxigalumicina |
Doxitard |
Doxivetin |
Doxteric |
DOXY |
Doxy 100 |
DOXY 200 |
Doxy-Caps |
Doxy-II |
Doxy-Lemmon |
Doxy-Puren |
Doxy-tablinen |
Doxy-Tabs |
Doxycen |
Doxychel |
Doxychel (TN) |
Doxychel Hyclate |
Doxycin |
Doxycyclin |
doxycycline |
Doxycycline (200mg/day) or Placebo |
Doxycycline (anhydrous) |
Doxycycline (hydrochloride) |
Doxycycline (INN) |
Doxycycline (internal use) |
Doxycycline (TN) |
Doxycycline [USAN:INN:BAN] |
Doxycycline anhydrous |
DOXYCYCLINE CALCIUM |
Doxycycline HCl |
Doxycycline Hyclate (100 mg) |
Doxycycline hyclate (internal use) |
Doxycycline hyclate (USP) |
Doxycycline hyclate [USAN:USP] |
doxycycline hyclate 20 mg twice daily |
Doxycycline hydrochloride |
Doxycycline Hydrochloride [JAN] |
Doxycycline hydrochloride hemiethanolate hemihydrate |
Doxycycline hydrochloride hydrate (JP17) |
DOXYCYCLINE HYLATE |
Doxycycline-Chinoin |
Doxycycline, Antibiotic for Culture Media Use Only |
Doxycycline, Hyclate |
Doxycycline, hydrochloride, hemiethanolate, hemihydrate; |
Doxycyclinum |
Doxycyclinum [INN-Latin] |
Doxylin |
Doxyprex |
Doxysol |
Doxytec |
Doxytetracycline |
DSSTox_CID_25405 |
DSSTox_GSID_45405 |
DSSTox_RID_80856 |
DTXSID0037653 |
DTXSID1045405 |
DTXSID4041020 |
Ecodox |
EINECS 209-271-1 |
EINECS 234-198-7 |
Ethanol, compd. with (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide monohydrochloride (1:2), monohydrate |
EU-0100405 |
FT-0603476 |
GS-3065 |
GS-3065 (*monohydrate) |
GTPL6464 |
HMS1920I20 |
HMS2090E06 |
HSDB 3071 |
HY-N0565A |
Hydramycin |
I015 |
I455 |
IDI1_000345 |
Idocyklin |
Investin |
J-000264 |
J10246 |
JBIWCJUYHHGXTC-AKNGSSGZSA-N |
Jenacyclin |
JRNIHERUNQWMMW-WBYAVNBMSA-N |
KBio1_000345 |
KBio2_001287 |
KBio2_003855 |
KBio2_006423 |
KBio3_001156 |
KBioGR_001133 |
KBioSS_001287 |
KS-5254 |
Liomycin |
Liviatin |
LMPK07000001 |
Lopac0_000405 |
LP00405 |
LS-174052 |
LS-187766 |
LS-93868 |
MCULE-4368118692 |
MCULE-8555113623 |
Mespafin |
MFCD07357237 |
Midoxin |
MMV000011 |
MolPort-002-507-423 |
MolPort-003-666-171 |
MolPort-005-932-536 |
MolPort-023-220-303 |
MolPort-039-338-208 |
MolPort-042-652-606 |
Monodoks |
Monodox |
Monodox (*monohydrate) |
NCGC00016693-01 |
NCGC00161602-01 |
NCGC00161602-03 |
NCGC00161602-04 |
NCGC00161602-05 |
NCGC00161602-06 |
NCGC00188979-01 |
NCGC00261090-01 |
NINDS_000345 |
Nivocilin |
Novadox |
Novo-Doxylin |
NPV78C39GQ |
NSC-633557 |
NSC-741421 |
NSC-756751 |
NSC633557 |
NSC741421 |
NSC756751 |
Nu-Doxycycline |
Oracea |
Oxytetracycline, 6-deoxy- |
Periostat |
Periostat (TN) |
Pharmakon1600-01500266 |
PL000396 |
PL040705 |
RETENS |
Ronaxan |
Roximycin |
RPRXAHFLWOCXQL-AKNGSSGZSA-N |
RUYHIJHUVHIMIR-CVHRZJFOSA-N |
Samecin |
SBI-0050391.P004 |
SC-15766 |
SCHEMBL17826665 |
SCHEMBL19270298 |
SCHEMBL40834 |
SCHEMBL40930 |
SCHEMBL66828 |
SGKRLCUYIXIAHR-AKNGSSGZSA-N |
SMP1_000107 |
Spanor |
SPBio_000246 |
Spectrum_000807 |
SPECTRUM1500266 |
Spectrum2_000143 |
Spectrum3_000408 |
Spectrum4_000527 |
Spectrum5_000947 |
SR-01000075844 |
SR-01000075844-7 |
STOCK1N-34341 |
Supracyclin |
Tanamicin |
Tecacin |
Tetraclean |
Tetradox |
Tox21_110566 |
Tox21_110566_1 |
Tox21_500405 |
UNII-19XTS3T51U |
UNII-334895S862 |
UNII-4182Z6T2ET |
UNII-NPV78C39GQ |
UPCMLD-DP021 |
UPCMLD-DP021:001 |
Vibra-tabs |
Vibra-tabs (TN) |
Vibradox |
Vibramycin |
Vibramycin (*monohydrate) |
Vibramycin (TN) |
Vibramycin hyclate |
Vibramycin hydrochloride |
Vibramycin Novum |
Vibramycin, Hyclate |
Vibramycine |
Vibravenos |
Vivox |
Vivox (*Hyclate) |
W-105517 |
WC 2031 |
Z2791720087 |
Zenavod |
ZINC100056779 |
ZINC100302137 |
ZINC100611210 |
ZINC109562088 |
ZINC16052277 |
US Patents and Regulatory Information for DOXYCYCLINE HYCLATE
Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Exclusivity Expiration |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ranbaxy | DOXYCYCLINE HYCLATE | doxycycline hyclate | CAPSULE;ORAL | 062479-001 | Dec 23, 1983 | DISCN | No | No | ➤ Try a Free Trial | ➤ Try a Free Trial | ➤ Try a Free Trial | ||||
Teva | DOXY-LEMMON | doxycycline hyclate | TABLET;ORAL | 062581-001 | Mar 15, 1985 | DISCN | No | No | ➤ Try a Free Trial | ➤ Try a Free Trial | ➤ Try a Free Trial | ||||
Mayne Pharma | DORYX MPC | doxycycline hyclate | TABLET, DELAYED RELEASE;ORAL | 050795-007 | May 20, 2016 | DISCN | Yes | No | ➤ Try a Free Trial | ➤ Try a Free Trial | Y | ➤ Try a Free Trial | |||
Mayne Pharma Inc | DOXYCYCLINE HYCLATE | doxycycline hyclate | TABLET;ORAL | 208765-002 | Jun 14, 2017 | AB | RX | No | No | ➤ Try a Free Trial | ➤ Try a Free Trial | ➤ Try a Free Trial | |||
Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Exclusivity Expiration |
Non-Orange Book US Patents for DOXYCYCLINE HYCLATE
For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.
The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.
Patent No. | Title | Estimated Patent Expiration |
---|---|---|
2,016,151,395 | ➤ Try a Free Trial | |
Patent No. | Title | Estimated Patent Expiration |
International Patents for DOXYCYCLINE HYCLATE
Country | Document Number | Estimated Expiration |
---|---|---|
Australia | 2005299253 | ➤ Try a Free Trial |
World Intellectual Property Organization (WIPO) | 2006045152 | ➤ Try a Free Trial |
Country | Document Number | Estimated Expiration |
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