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DOXYCYCLINE HYCLATE Drug Profile
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Which patents cover Doxycycline Hyclate, and when can generic versions of Doxycycline Hyclate launch?
Doxycycline Hyclate is a drug marketed by Pliva, Medicis, Actavis Labs Fl Inc, Alembic Pharms Ltd, Amneal Pharms, Chartwell Life Sci, Halsey, Heather, Hikma Intl Pharms, Interpharm, Mutual Pharm, Mylan, Par Pharm, Pvt Form, Ranbaxy, Sun Pharm Industries, Superpharm, Warner Chilcott, Watson Labs, Zydus Pharms Usa Inc, West-ward Pharms Int, Actavis Elizabeth, Heritage Pharms Inc, Impax Labs Inc, Mylan Pharms Inc, Prinston Inc, Amneal Pharms Co, Caribe Holdings, Epic Pharma Llc, Ivax Sub Teva Pharms, Lannett Co Inc, Larken Labs, Lupin Ltd, Mayne Pharma Inc, Novel Labs Inc, and Vintage Pharms. and is included in fifty-three NDAs.
The generic ingredient in DOXYCYCLINE HYCLATE is doxycycline hyclate. There are twenty-seven drug master file entries for this compound. Ninety-eight suppliers are listed for this compound. Additional details are available on the doxycycline hyclate profile page.
Summary for DOXYCYCLINE HYCLATE
Pharmacology for DOXYCYCLINE HYCLATE
| Ingredient-type | Tetracyclines |
| Drug Class | Tetracycline-class Drug |
Synonyms for DOXYCYCLINE HYCLATE
| (1S,4aS,11R,11aR,12S,12aR)-3-carbamoyl-2,4a,5,7,12-pentahydroxy-N,N,11-trimethyl-4,6-dioxo-1,4,4a,6,11,11a,12,12a-octahydrotetracen-1-aminium chloride--ethanol--water (2/1/1) |
| (2E,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione |
| (2E,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione; ethanol; hydrate; dihydrochloride |
| (2Z,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione; ethanol; hydrate; dihydrochloride |
| (2Z,4S,4AR,5S,5AR,6R,12AS)-2-[AMINO(HYDROXY)METHYLIDENE]-4-(DIMETHYLAMINO)-5,10,11,12A-TETRAHYDROXY-6-METHYL-1,2,3,4,4A,5,5A,6,12,12A-DECAHYDROTETRACENE-1,3,12-TRIONE |
| (2Z,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione |
| (2Z,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione hydrochloride |
| (2Z,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione; ethanol; hydrate; dihydrochloride |
| (2Z,4S,4aR,5S,5aR,6R)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione |
| (2Z)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione |
| (4S,4aR,5S,5aR,6R,12aR)-4-(dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide |
| (4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione |
| (4S,4aR,5S,5aR,6R,12aS)-4-(Dimethylamino)- 3,5,10,12,12a-pentahydroxy- 6-methyl- 1,11-dioxo- 1,4,4a,5,5a,6,11,12a-octahydrotetracene- 2-carboxamide hydrochloride hemiethanolate hemihydrate |
| (4s,4ar,5s,5ar,6r,12as)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide |
| (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide |
| (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide - ethanol (2:1) dihydrochloride hydrate |
| (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide compound with ethanol (2:1) dihydrochloride hydrate |
| (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide |
| (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide;ethanol;hydrate;dihydrochloride |
| 100929-47-3 |
| 10592-13-9 |
| 10592-13-9 (. HCl) |
| 10597-92-9 |
| 1368-EP2269978A2 |
| 1368-EP2269985A2 |
| 1368-EP2269991A2 |
| 1368-EP2284150A2 |
| 1368-EP2284151A2 |
| 1368-EP2284152A2 |
| 1368-EP2284153A2 |
| 1368-EP2284155A2 |
| 1368-EP2284156A2 |
| 1368-EP2284164A2 |
| 1368-EP2287140A2 |
| 1368-EP2287148A2 |
| 1368-EP2287150A2 |
| 1368-EP2289871A1 |
| 1368-EP2295402A2 |
| 1368-EP2295419A2 |
| 1368-EP2298732A1 |
| 1368-EP2301534A1 |
| 1368-EP2301912A2 |
| 1368-EP2301913A1 |
| 1368-EP2301914A1 |
| 1368-EP2301916A2 |
| 1368-EP2305637A2 |
| 1368-EP2305640A2 |
| 1368-EP2308863A1 |
| 1368-EP2311451A1 |
| 1368-EP2311796A1 |
| 1368-EP2311797A1 |
| 1368-EP2311798A1 |
| 1368-EP2311799A1 |
| 1368-EP2316450A1 |
| 17086-28-1 (mono-hydrate) |
| 19XTS3T51U |
| 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a, 5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy -6-methyl-1,11-dioxo-, monohydrochloride, (4S,4aR,5S,5aR,6R,12aS)-, compd. with ethanol (2:1), mono |
| 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S-(4alpha,4aalpha,5alpha,5aalpha,6alpha,12aalpha))- |
| 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S,4aR,5S,5aR,6R,12aS) |
| 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S,4aR,5S,5aR,6R,12aS)- |
| 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride, (4S,4aR,5S,5aR,6R,12aS)-, compd. with ethanol, hydrate (2:2:1:1) |
| 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, (4S-(4alpha,4aalpha,5alpha,5aalpha,6alpha,12aalpha))- |
| 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, (4S,4aR,5S,5aR,6R,12aS)- |
| 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, compd. with ethanol (2:1), monohydrate, (4S-(4alpha,4aalpha,5alpha,5aalpha,6alpha, |
| 2-Naphthacenecarboxamide, 4-alpha-S-(dimethylamino)-1,4,4a-alpha-5,5a-alpha,6,11,12a-octahydro-3,5-alpha,10,12,12a-alpha-pentahydroxy-6-alpha-methyl-1,11-dioxo- |
| 2-Naphthacenecarboxamide, 4-dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride |
| 2-Naphthacenecarboxamide, 4beta-(dimeethylamino)-1,4,4abeta,5,5abeta,6,11,12a-octahydro-3,5beta,10,12,12abeta-pentahydroxy-6beta-methyl-1,11-dioxo-, monohydrochloride, compd. with ethyl alcohol (2:1), monohydrate |
| 2-Naphthacenecarboxamide,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, (4S,4aR,5S,5aR,6R,12aS)-, compd. with ethanol (2:1), monohydrate (9CI) (CA INDEX NAME) |
| 2387AH |
| 24390-14-5 |
| 2C22H24N2O8.C2H6O.2ClH.H2O |
| 2C22H24N2O8.C2H6O.H2O |
| 334895S862 |
| 390D145 |
| 4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide monohydrochloride, compound with ethyl alcohol (2:1), monohydrate |
| 4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide - ethanol (2:1) dihydrochloride hydrate |
| 4-Epioxytetracycline, 6-deoxy- |
| 41411-66-9 (6-epimer, mono-hydrochloride) |
| 4182Z6T2ET |
| 5-Hydroxy-alpha-6-deoxytetracycline |
| 5-Hydroxy-alpha-6-deoxytetracycline monohydrate |
| 53108-42-2 |
| 564-25-0 |
| 564D250 |
| 6-alpha-Deoxy-5-oxytetracycline |
| 6-Deoxy-5-hydroxytetracycline hydrochloride hemihydrate |
| 6-Deoxyoxytetracycline |
| 6-Deoxytetracycline |
| 6-Desoxy-5-hydroxytetracycline hydrochloride hemihydrate hemiethanolate |
| 61281-03-6 |
| 62149-53-5 |
| 69935-17-7 (mono-hydrochloride, di-hydrate) |
| 6alpha-Deoxy-5-oxytetracycline |
| 7164-70-7 |
| 7264-10-0 |
| 94088-85-4 (calcium salt (1:2)) |
| AB00053465_04 |
| AB00053465_05 |
| AB00053465-03 |
| AB08 (*Fosfatex) |
| AC-12044 |
| AC-6017 |
| AC1L1WYQ |
| AC1NQXW7 |
| AC1NQZPV |
| AC1NTTH2 |
| AC1NUYS5 |
| AC1NUYS8 |
| Acticlate |
| Acticlate CAP |
| AK321970 |
| AK322076 |
| AKOS015900372 |
| AKOS015924649 |
| AKOS025310153 |
| AKOS025402170 |
| alpha-6-Deoxy-5-hydroxytetracycline |
| alpha-6-Deoxyoxytetracycline |
| alpha-6-Deoxyoxytetracycline monohydrate |
| alpha-6-Tetracycline monohydrate |
| alpha-Doxycycline |
| Alti-Doxycycline |
| Ambap100929-47-3 |
| AN-18097 |
| Anhydrous doxycycline |
| API0002491 |
| API0002492 |
| Apo-Doxy |
| AS-13499 |
| Atridox |
| Azudoxat |
| BCBcMAP01_000024 |
| Biocamycin |
| bis((4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide) ethanol hydrate dihydrochloride |
| BMY 28689 |
| BMY-28689 |
| BMY28689 |
| BSPBio_001936 |
| BU 3839T |
| BU-3839T |
| C-0055 |
| C06973 |
| C22H24N2O8.HCl.0.5H2O.0.5C2H6O |
| C22H25ClN2O8 |
| CAS-10592-13-9 |
| CCG-204498 |
| CCG-38949 |
| CHEBI:34730 |
| CHEBI:50845 |
| CHEBI:652992 |
| CHEMBL1200567 |
| CHEMBL1256723 |
| CHEMBL1433 |
| CHEMBL436921 |
| CS-2632 |
| D 9891 |
| D02129 |
| D07876 |
| D07877 |
| D0S0LZ |
| D4116 |
| DB00254 |
| Dentista |
| Deoxy-5-hydroxytetracycline hydrochloride |
| Deoxymykoin |
| Deoxyoxytetracycline hydrochloride |
| DivK1c_000345 |
| DMSC (*Fosfatex) |
| Doryx |
| Doryx (TN) |
| Doryx Mpc |
| Dossiciclina |
| Dossiciclina [DCIT] |
| DOXCYCLINE ANHYDROUS |
| Doxiciclina |
| Doxiciclina [INN-Spanish] |
| Doxiciclina [Italian] |
| Doxigalumicina |
| Doxitard |
| Doxivetin |
| Doxteric |
| DOXY |
| Doxy 100 |
| DOXY 200 |
| Doxy-Caps |
| Doxy-II |
| Doxy-Lemmon |
| Doxy-Puren |
| Doxy-tablinen |
| Doxy-Tabs |
| Doxycen |
| Doxychel |
| Doxychel (TN) |
| Doxychel Hyclate |
| Doxycin |
| Doxycyclin |
| doxycycline |
| Doxycycline (200mg/day) or Placebo |
| Doxycycline (anhydrous) |
| Doxycycline (hydrochloride) |
| Doxycycline (INN) |
| Doxycycline (internal use) |
| Doxycycline (TN) |
| Doxycycline [USAN:INN:BAN] |
| Doxycycline anhydrous |
| DOXYCYCLINE CALCIUM |
| Doxycycline HCl |
| Doxycycline Hyclate (100 mg) |
| Doxycycline hyclate (internal use) |
| Doxycycline hyclate (USP) |
| Doxycycline hyclate [USAN:USP] |
| doxycycline hyclate 20 mg twice daily |
| Doxycycline hydrochloride |
| Doxycycline Hydrochloride [JAN] |
| Doxycycline hydrochloride hemiethanolate hemihydrate |
| Doxycycline hydrochloride hydrate (JP17) |
| DOXYCYCLINE HYLATE |
| Doxycycline-Chinoin |
| Doxycycline, Antibiotic for Culture Media Use Only |
| Doxycycline, Hyclate |
| Doxycycline, hydrochloride, hemiethanolate, hemihydrate; |
| Doxycyclinum |
| Doxycyclinum [INN-Latin] |
| Doxylin |
| Doxyprex |
| Doxysol |
| Doxytec |
| Doxytetracycline |
| DSSTox_CID_25405 |
| DSSTox_GSID_45405 |
| DSSTox_RID_80856 |
| DTXSID0037653 |
| DTXSID1045405 |
| DTXSID4041020 |
| Ecodox |
| EINECS 209-271-1 |
| EINECS 234-198-7 |
| Ethanol, compd. with (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide monohydrochloride (1:2), monohydrate |
| EU-0100405 |
| FT-0603476 |
| GS-3065 |
| GS-3065 (*monohydrate) |
| GTPL6464 |
| HMS1920I20 |
| HMS2090E06 |
| HSDB 3071 |
| HY-N0565A |
| Hydramycin |
| I015 |
| I455 |
| IDI1_000345 |
| Idocyklin |
| Investin |
| J-000264 |
| J10246 |
| JBIWCJUYHHGXTC-AKNGSSGZSA-N |
| Jenacyclin |
| JRNIHERUNQWMMW-WBYAVNBMSA-N |
| KBio1_000345 |
| KBio2_001287 |
| KBio2_003855 |
| KBio2_006423 |
| KBio3_001156 |
| KBioGR_001133 |
| KBioSS_001287 |
| KS-5254 |
| Liomycin |
| Liviatin |
| LMPK07000001 |
| Lopac0_000405 |
| LP00405 |
| LS-174052 |
| LS-187766 |
| LS-93868 |
| MCULE-4368118692 |
| MCULE-8555113623 |
| Mespafin |
| MFCD07357237 |
| Midoxin |
| MMV000011 |
| MolPort-002-507-423 |
| MolPort-003-666-171 |
| MolPort-005-932-536 |
| MolPort-023-220-303 |
| MolPort-039-338-208 |
| MolPort-042-652-606 |
| Monodoks |
| Monodox |
| Monodox (*monohydrate) |
| NCGC00016693-01 |
| NCGC00161602-01 |
| NCGC00161602-03 |
| NCGC00161602-04 |
| NCGC00161602-05 |
| NCGC00161602-06 |
| NCGC00188979-01 |
| NCGC00261090-01 |
| NINDS_000345 |
| Nivocilin |
| Novadox |
| Novo-Doxylin |
| NPV78C39GQ |
| NSC-633557 |
| NSC-741421 |
| NSC-756751 |
| NSC633557 |
| NSC741421 |
| NSC756751 |
| Nu-Doxycycline |
| Oracea |
| Oxytetracycline, 6-deoxy- |
| Periostat |
| Periostat (TN) |
| Pharmakon1600-01500266 |
| PL000396 |
| PL040705 |
| RETENS |
| Ronaxan |
| Roximycin |
| RPRXAHFLWOCXQL-AKNGSSGZSA-N |
| RUYHIJHUVHIMIR-CVHRZJFOSA-N |
| Samecin |
| SBI-0050391.P004 |
| SC-15766 |
| SCHEMBL17826665 |
| SCHEMBL19270298 |
| SCHEMBL40834 |
| SCHEMBL40930 |
| SCHEMBL66828 |
| SGKRLCUYIXIAHR-AKNGSSGZSA-N |
| SMP1_000107 |
| Spanor |
| SPBio_000246 |
| Spectrum_000807 |
| SPECTRUM1500266 |
| Spectrum2_000143 |
| Spectrum3_000408 |
| Spectrum4_000527 |
| Spectrum5_000947 |
| SR-01000075844 |
| SR-01000075844-7 |
| STOCK1N-34341 |
| Supracyclin |
| Tanamicin |
| Tecacin |
| Tetraclean |
| Tetradox |
| Tox21_110566 |
| Tox21_110566_1 |
| Tox21_500405 |
| UNII-19XTS3T51U |
| UNII-334895S862 |
| UNII-4182Z6T2ET |
| UNII-NPV78C39GQ |
| UPCMLD-DP021 |
| UPCMLD-DP021:001 |
| Vibra-tabs |
| Vibra-tabs (TN) |
| Vibradox |
| Vibramycin |
| Vibramycin (*monohydrate) |
| Vibramycin (TN) |
| Vibramycin hyclate |
| Vibramycin hydrochloride |
| Vibramycin Novum |
| Vibramycin, Hyclate |
| Vibramycine |
| Vibravenos |
| Vivox |
| Vivox (*Hyclate) |
| W-105517 |
| WC 2031 |
| Z2791720087 |
| Zenavod |
| ZINC100056779 |
| ZINC100302137 |
| ZINC100611210 |
| ZINC109562088 |
| ZINC16052277 |
US Patents and Regulatory Information for DOXYCYCLINE HYCLATE
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Exclusivity Expiration |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lannett Co Inc | DOXYCYCLINE HYCLATE | doxycycline hyclate | TABLET;ORAL | 065277-001 | Nov 10, 2005 | AB | RX | No | Yes | ➤ Sign Up | ➤ Sign Up | ➤ Sign Up | |||
| Zydus Pharms Usa Inc | DOXYCYCLINE HYCLATE | doxycycline hyclate | CAPSULE;ORAL | 207774-002 | May 31, 2018 | AB | RX | No | No | ➤ Sign Up | ➤ Sign Up | ➤ Sign Up | |||
| Superpharm | DOXYCYCLINE HYCLATE | doxycycline hyclate | CAPSULE;ORAL | 062469-001 | Oct 31, 1984 | DISCN | No | No | ➤ Sign Up | ➤ Sign Up | ➤ Sign Up | ||||
| Watson Labs | DOXYCYCLINE HYCLATE | doxycycline hyclate | TABLET;ORAL | 062392-001 | Mar 31, 1983 | DISCN | No | No | ➤ Sign Up | ➤ Sign Up | ➤ Sign Up | ||||
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Exclusivity Expiration |
see a sample report or, see our see our flat-rate plans
see a sample report or, see our see our flat-rate plans
