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Generated: June 24, 2018

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Timolol - Generic Drug Details

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What are the generic sources for timolol and what is the scope of timolol freedom to operate?

Timolol
is the generic ingredient in eight branded drugs marketed by Oak Pharms Inc, Akorn, Sandoz Inc, Valeant Pharms Llc, Bausch And Lomb, Apotex Inc, Fdc Ltd, Fougera, Hi Tech Pharma, Pacific Pharma, Wockhardt, Aton, Merck, Mylan, Quantum Pharmics, Teva, Usl Pharma, Watson Labs, and Yaopharma Co Ltd, and is included in forty-five NDAs. There are three patents protecting this compound. Additional information is available in the individual branded drug profile pages.

There are fifteen drug master file entries for timolol. Three suppliers are listed for this compound. There is one tentative approval for this compound.
Pharmacology for timolol
Medical Subject Heading (MeSH) Categories for timolol
Synonyms for timolol
(-)-3-Morpholino-4-(3-tert-butylamino-2-hydroxypropoxy)-1,2,5-thiadiazole
(-)-Timolol
(2S)-1-((1,1-dimethylethyl)amino)-3-((4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl)oxy)-2-propanol
(2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol
(2S)-1-(tert-butylamino)-3-{[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy}propan-2-ol
(2S)-1-[(1,1-dimethylethyl)amino]-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol
(2S)-3-[(tert-butyl)amino]-1-(4-morpholin-4-yl(1,2,5-thiadiazol-3-yl)oxy)propa n-2-ol
(S)-1-(1,1-(Dimethylethyl)amino)-3-((4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl)oxy)-2-propanol
(S)-1-(tert-Butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-ol
(S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol
(S)-1-tert-Butylamino-3-(4-morpholin-4-yl-[1,2,5]thiadiazol-3-yloxy)-propan-2-ol
(S)-timolol
(S)-timolol (anhydrous)
1-(tert-butylamino)-3-[4-(1,4-oxazinan-4-yl)-1,2,5-thiadiazol-3-yloxy]-(2S)-propan-2-ol
131628-37-0
194288-09-0
2-Propanol, 1-((1,1-dimethylethyl)amino)-3-((4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl)oxy)-, (2S)-
2-Propanol, 1-((1,1-dimethylethyl)amino)-3-((4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl)oxy)-, (S)-
2-Propanol, 1-[(1,1-dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-, (2S)-
2-Propanol,1-[(1,1-dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-,(2S)-
26839-75-8
26921-17-5 (maleate (1:1) salt)
5JKY92S7BR
839T758
AB00513729
AB00513729-17
AC1L1PYN
AC1Q59QM
AKOS015969764
API0004422
Apo-Timol
Apo-Timol (TN)
Apo-Timop
Apo-Timop (TN)
Aquanil
ARONIS24479
arutimol
BBC/645
BDBM50292219
Betim
Betimol
Betimol (TN)
BIDD:GT0073
BLJRIMJGRPQVNF-JTQLQIEISA-N
Blocadren
Blocadren (TN)
BPBio1_001008
BRD-K08806317-050-03-6
BSPBio_000916
C-19486
C07141
CAS-26839-75-8
CAS-26921-17-5
CC-35068
CHEBI:9599
CHEMBL499
CTK4F8602
D05UVD
D08600
DB00373
DSSTox_CID_3674
DSSTox_GSID_23674
DSSTox_RID_77140
DTXSID4023674
EINECS 248-032-6
FT-0630529
Gen-Timolol (TN)
GTPL565
HE061310
HE330337
HMS2089I11
HMS3259C20
HSDB 6533
Istalol
Istalol (TN)
L-714,465
L-Timolol
Lopac-T-6394
Lopac0_001189
LS-122231
MK-950
MolPort-006-125-123
NC00592
NCGC00016038-01
NCGC00016038-02
NCGC00016798-01
NCGC00016798-02
NCGC00016798-03
NCGC00016798-05
NCGC00016798-06
NCGC00016798-07
NCGC00016798-08
NCGC00016798-09
NCGC00016798-11
NCGC00022033-02
NCGC00022033-04
NCGC00022033-05
Novo-Timol
Nu-Timolol
Nu-Timolol (TN)
Oprea1_640981
Optimol
Phoxal-timolol
Phoxal-timolol (TN)
PMS-Timolol (TN)
Prestwick0_000948
Prestwick1_000948
Prestwick2_000948
Prestwick3_000948
Proflax
S-(-)-3-(3-tert-Butylamino-2-hydroxypropoxy)-4-morpholino-1,2,5-thiadiazole
S(-)-Timolol maleate
SCHEMBL4912
SPBio_003075
ST072193
Temserin
Tenopt
TIM
Tim-AK
Tim-AK (TN)
Timacar
Timacor
Timolol (INN)
Timolol (TN)
Timolol [USAN:INN]
Timolol [USAN]
Timolol anhydrous
Timolol GFS
Timolol maleate
Timolol Maleate, (1:1) Salt
Timololo
Timololum
Timololum [INN-Latin]
Timopic
Timoptic
Timoptic (TN)
Timoptic OcuDose
Timoptic OcuDose. (TN)
Timoptic-XE
Timoptic-XE (TN)
Timoptol
Tocris-0649
Tox21_110614
Tox21_110614_1
UNII-5JKY92S7BR
W-107148
ZINC2176
Tentative approvals for TIMOLOL
Applicant Application No. Strength Dosage Form
➤ Try a Free Trial➤ Try a Free Trial0.5%SOLUTION;OPHTHALMIC

US Patents and Regulatory Information for timolol

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Valeant Pharms Llc TIMOPTIC-XE timolol maleate SOLUTION, GEL FORMING/DROPS;OPHTHALMIC 020330-001 Nov 4, 1993 AB RX Yes Yes ➤ Try a Free Trial ➤ Try a Free Trial ➤ Try a Free Trial
Akorn TIMOLOL MALEATE timolol maleate SOLUTION/DROPS;OPHTHALMIC 074465-001 Mar 25, 1997 DISCN No No ➤ Try a Free Trial ➤ Try a Free Trial ➤ Try a Free Trial
Sandoz Inc TIMOLOL MALEATE timolol maleate SOLUTION/DROPS;OPHTHALMIC 074262-001 Apr 28, 1995 AT1 RX No Yes ➤ Try a Free Trial ➤ Try a Free Trial ➤ Try a Free Trial
Bausch And Lomb TIMOLOL MALEATE timolol maleate SOLUTION/DROPS;OPHTHALMIC 074776-001 Mar 25, 1997 AT1 RX No No ➤ Try a Free Trial ➤ Try a Free Trial ➤ Try a Free Trial
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration

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Expired US Patents for timolol

Applicant Tradename Generic Name Dosage NDA Approval Date Patent No. Patent Expiration
Oak Pharms Inc BETIMOL timolol SOLUTION/DROPS;OPHTHALMIC 020439-001 Mar 31, 1995 ➤ Try a Free Trial ➤ Try a Free Trial
Oak Pharms Inc BETIMOL timolol SOLUTION/DROPS;OPHTHALMIC 020439-002 Mar 31, 1995 ➤ Try a Free Trial ➤ Try a Free Trial
Applicant Tradename Generic Name Dosage NDA Approval Date Patent No. Patent Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Teva
Johnson and Johnson
Chinese Patent Office
US Army
UBS
Baxter
Colorcon
Farmers Insurance
Deloitte

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