DrugPatentWatch Database Preview
Diltiazem hydrochloride - Generic Drug Details
see a sample report or, see our see our flat-rate plans
What are the generic drug sources for diltiazem hydrochloride and what is the scope of diltiazem hydrochloride freedom to operate?
Diltiazem hydrochloride
is the generic ingredient in eleven branded drugs marketed by Valeant Intl, Biovail, Actavis Labs Fl Inc, Allergan Sales Llc, Apotex, Actavis Elizabeth, Mylan, Nesher Pharms, Par Pharm, Sandoz, Sun Pharm Inds Ltd, Sun Pharma Global, Teva, Valeant Pharms North, Zydus Pharms Usa Inc, Apotex Inc, Biovail Labs Intl, Akorn Inc, Athenex Inc, Hikma Farmaceutica, Hospira, Intl Medication, Mylan Labs Ltd, Teva Pharms Usa, West-ward Pharms Int, Apothecon, Chartwell Molecules, Ivax Sub Teva Pharms, and Teva Pharms, and is included in forty-nine NDAs. There are two patents protecting this compound and two Paragraph IV challenges. Additional information is available in the individual branded drug profile pages.Diltiazem hydrochloride has twenty-two patent family members in eleven countries.
There are twenty-six drug master file entries for diltiazem hydrochloride. Forty-five suppliers are listed for this compound.
Summary for diltiazem hydrochloride
| International Patents: | 22 |
| US Patents: | 2 |
| Tradenames: | 11 |
| Applicants: | 29 |
| NDAs: | 49 |
| Drug Master File Entries: | 26 |
| Suppliers / Packagers: | 45 |
| Bulk Api Vendors: | 78 |
| Clinical Trials: | 76 |
| Patent Applications: | 3,660 |
| Formulation / Manufacturing: | see details |
| Patent Litigation and PTAB cases: | See patent lawsuits and PTAB cases for diltiazem hydrochloride |
| DailyMed Link: | diltiazem hydrochloride at DailyMed |
Pharmacology for diltiazem hydrochloride
| Drug Class | Calcium Channel Blocker |
| Mechanism of Action | Calcium Channel Antagonists |
Synonyms for diltiazem hydrochloride
| (+)-5-(2-(Dimethylamino)ethyl)-cis-2,3-dihydro-3-hydroxy-2-(p-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one acetate (ester) monohydrochloride |
| (+)-5-(2-(dimethylamino)ethyl)-cis-2,3-dihydro-3-hydroxy-2-(p-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one acetate ester monohydrochloride |
| (+)-cis-Diltiazem hydrochloride |
| (+)-cis-Diltiazem hydrochloride, >=99% (HPLC) |
| (2S-cis)-3-(Acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one hydrochloride |
| (2S-cis)-3-Acetoxy-5-(2-(dimethylamino)ethyl)-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one monohydrochloride |
| (2S-trans)-Diltiazem Hydrochloride |
| (2S,3S)-(+)-3-Acetoxy-2,3-dihydro-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one Hydrochloride |
| (2S,3S)-(+)-cis-3-Acetoxy-5-(2-dimethylaminoethyl)-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one hydrochloride |
| (2S,3S)-5-(2-(dimethylamino)ethyl)-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl acetate hydrochloride |
| (2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate hydrochloride |
| (2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2H,3H-benzo[b]1,4 -thiazaperhydroepin-3-yl acetate, chloride |
| [(2S,3S)-5-(2-dimethylaminoethyl)-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate hydrochloride |
| [(2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate;hydrochloride |
| 1,5-Benzothiazepin-4(5H)-one, 2,3-dihydro-3-(acetyloxy)-5-(2-(dimethylamino)ethyl)-2-(4-methoxyphenyl)-, monohydrochloride, cis-(+)- |
| 1,5-Benzothiazepin-4(5H)-one, 3-(acetyloxy)-5-(2-(dimethylamino)ethyl)-2,3-dihydro-2-(4-methoxyphenyl)-, monohydrochloride, (+)-cis- |
| 103532-26-9 |
| 2-[(2S,3S)-3-(acetyloxy)-2-(4-methoxyphenyl)-4-oxo-3,4-dihydro-1,5-benzothiazepin-5(2H)-yl]-N,N-dimethylethanaminium chloride |
| 286D225 |
| 33286-22-5 |
| 38411-61-9 |
| AB2000340 |
| AC-15189 |
| AC1L1Y1J |
| AC1Q3C2G |
| AC1Q3EQ4 |
| Acetic acid (2S,3S)-5-(2-dimethylamino-ethyl)-2-(4-methoxy-phenyl)-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]thiazepin-3-yl ester; hydrochloride |
| ACT02682 |
| Adizem-CD |
| AK162004 |
| AKOS015961992 |
| Altiazem |
| Altiazem Retard |
| Altiazem RR |
| Anginyl |
| Angiotrofin |
| Angiotrofin Retard |
| Angitil |
| Angizem |
| Anzem |
| Apo-diltiazem |
| AS-13703 |
| BC208729 |
| Bi-Tildiem |
| BIM-0050315.0001 |
| BNP-32762 |
| Britiazim |
| Bruzem |
| C22H26N2O4S.HCl |
| Calcicard |
| Calnurs |
| Cardiazem |
| Cardil Retard |
| Cardizem (TN) |
| Cardizem CD |
| Cardizem LA |
| Cardizem Retard |
| Cardizem SR |
| Cardizem XL |
| Cardizem;Tiazac |
| Carex |
| Cartia XT |
| Cartia XT (TN) |
| Carzem |
| Carzen |
| CCG-220134 |
| CCG-221631 |
| CHEBI:645509 |
| CHEMBL1697 |
| Cirilen |
| Cirilen AP |
| cis-(+)-3-acetoxy-2,3-dihydro-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-1,5-benzothiazepine-4(5H)-one hydrochloride |
| cis-(1)-3-Acetoxy-5-(2-(dimethylamino)ethyl)-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one monohydrochloride |
| Citizen |
| Clarute |
| Coras |
| Corazet |
| CPD000058375 |
| CRD 401 |
| CRD-401 |
| CS-2339 |
| CTK8E8855 |
| D 2521 |
| D00616 |
| D3662 |
| Dazil |
| Deltazen |
| Diacor |
| Diatal |
| Dil-Sonaramia |
| Dilacor XR (TN) |
| Dilacor XR Extended Release Capsules |
| Diladel |
| Dilatam |
| Dilatam 120 |
| Dilatame |
| Dilcard |
| Dilem |
| Dilfar |
| Dilgard |
| Dilicardin |
| Dilpral |
| Dilrene |
| Dilsal |
| Dilso |
| Dilt-CD (TN) |
| Dilt-XR |
| Diltahexal |
| Diltam |
| Diltan |
| Diltan SR |
| Diltelan |
| Dilthiazem hydrochloride |
| Dilthiazemhydrochloride |
| Diltia XT |
| Diltiasyn |
| Diltiazem (hydrochloride) |
| Diltiazem AWD |
| Diltiazem Basics |
| Diltiazem chloridrate |
| Diltiazem Eu Rho |
| Diltiazem for system suitability, European Pharmacopoeia (EP) Reference Standard |
| Diltiazem GNR |
| Diltiazem HCl |
| Diltiazem HCl (Tiazac) |
| Diltiazem Henning |
| Diltiazem hydrochloride (JP17/USP) |
| Diltiazem hydrochloride [USAN:JAN] |
| Diltiazem hydrochloride [USAN:USP:JAN] |
| Diltiazem Hydrochloride 1.0 mg/ml in Acetonitrile (as free base) |
| Diltiazem hydrochloride solution, 1.0 mg/mL in acetonitrile (as free base), ampule of 1 mL, certified reference material |
| Diltiazem hydrochloride, European Pharmacopoeia (EP) Reference Standard |
| Diltiazem hydrochloride, United States Pharmacopeia (USP) Reference Standard |
| Diltiazem Merck |
| Diltiazem MSD |
| Diltiazem Stada |
| Diltiazem UPSA |
| Diltiazem Verla |
| Diltiazem-Cophar |
| Diltiazem-GRY |
| Diltiazem-Isis |
| Diltiazem-Mepha |
| Diltiazem, Hydrochloride |
| Diltikor |
| Diltime |
| Dilzem |
| Dilzem Retard |
| Dilzem RR |
| Dilzene |
| Dilzereal 90 Retard |
| Dilzicardin |
| Dinisor |
| Dinisor Retard |
| Doclis |
| Dodexen |
| Dodexen A.P |
| Dodexen A.P. |
| Dolizem |
| DOV diltiazem |
| DTXSID8040147 |
| Dyalac |
| EINECS 251-443-3 |
| EINECS 253-918-0 |
| Entrydil |
| Etizen |
| Etyzen |
| EU-0100327 |
| Farmabes |
| FT-0625017 |
| FT-0667217 |
| Gadoserin |
| Hart |
| HDRXZJPWHTXQRI-BHDTVMLSSA-N |
| HE005229 |
| Helsibon |
| Herben |
| Herbesser |
| Herbesser 180 SR |
| Herbesser 60 |
| Herbesser 90 SR |
| Hesor |
| HMS1568K10 |
| HY-14656 |
| Incoril |
| Iski |
| Iski-90 SR |
| J-019130 |
| J10138 |
| Jsp006114 |
| Kaltiazen |
| Kardil |
| KS-5089 |
| Lacerol |
| Levozem |
| Longazem |
| LP00327 |
| LS-40513 |
| Lytelsen |
| Masdil |
| Metazem |
| MFCD00069252 |
| Milptin |
| Miocardie |
| MK-793 |
| MLS000028432 |
| MLS001148257 |
| MLS002222179 |
| MolPort-003-931-523 |
| Mono-Tildiem |
| Myonil |
| Myonil Retard |
| NC00558 |
| NCGC00093768-01 |
| NCGC00261012-01 |
| NE54505 |
| Novo-Diltazem |
| OLH94387TE |
| Opera_ID_79 |
| Oxycardil |
| Pazeadin |
| Pentilzeno |
| Poltiazem |
| Presoken |
| Presokin A. P |
| Presokin A. P. |
| Prestwick_176 |
| RG 83606 |
| RG 83606 HCl |
| RG-83606 |
| RT-014406 |
| s1865 |
| SAM002564204 |
| SC-18679 |
| SCHEMBL15457 |
| Slozem |
| Slozen |
| SLV-324 |
| SMR000058375 |
| SR-01000075327 |
| SR-01000075327-1 |
| ST24046586 |
| ST50320016 |
| Surazem |
| Syn-Diltiazem |
| Tazem |
| Taztia XT |
| Tiadil |
| Tiaves |
| Tiazac |
| Tiazac extended release |
| Tilazem |
| Tilazem 90 |
| Tilazem AS 60 |
| Tilazem AS 90 |
| Tildiem |
| Tildiem CR |
| Tildiem LA |
| Tildiem Retard |
| Tox21_500327 |
| Trumsal |
| Ubicor |
| Uni Masdil |
| Uni-Masdil |
| UNII-OLH94387TE |
| VEN-307 |
| Viazem SR |
| Viazem XL |
| WL Diltiazem |
| Zildem |
| Zilden |
| Ziruvate |
US Patents and Regulatory Information for diltiazem hydrochloride
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Exclusivity Expiration |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sun Pharm Inds Ltd | DILTIAZEM HYDROCHLORIDE | diltiazem hydrochloride | CAPSULE, EXTENDED RELEASE;ORAL | 203023-003 | Jun 8, 2017 | AB3 | RX | No | No | ➤ Sign Up | ➤ Sign Up | ➤ Sign Up | |||
| Apotex Inc | DILTZAC | diltiazem hydrochloride | CAPSULE, EXTENDED RELEASE;ORAL | 076395-004 | Feb 1, 2006 | AB4 | RX | No | No | ➤ Sign Up | ➤ Sign Up | ➤ Sign Up | |||
| Valeant Pharms North | TIAZAC | diltiazem hydrochloride | CAPSULE, EXTENDED RELEASE;ORAL | 020401-003 | Sep 11, 1995 | AB4 | RX | Yes | No | ➤ Sign Up | ➤ Sign Up | ➤ Sign Up | |||
| Actavis Labs Fl Inc | TAZTIA XT | diltiazem hydrochloride | CAPSULE, EXTENDED RELEASE;ORAL | 075401-001 | Apr 10, 2003 | AB4 | RX | No | No | ➤ Sign Up | ➤ Sign Up | ➤ Sign Up | |||
| Nesher Pharms | DILTIAZEM HYDROCHLORIDE | diltiazem hydrochloride | CAPSULE, EXTENDED RELEASE;ORAL | 076563-005 | Sep 12, 2006 | DISCN | No | No | ➤ Sign Up | ➤ Sign Up | ➤ Sign Up | ||||
| Biovail | DILTIAZEM HYDROCHLORIDE | diltiazem hydrochloride | CAPSULE, EXTENDED RELEASE;ORAL | 074845-001 | Sep 15, 1999 | DISCN | No | No | ➤ Sign Up | ➤ Sign Up | ➤ Sign Up | ||||
| Actavis Labs Fl Inc | CARTIA XT | diltiazem hydrochloride | CAPSULE, EXTENDED RELEASE;ORAL | 074752-002 | Jul 9, 1998 | AB3 | RX | No | No | ➤ Sign Up | ➤ Sign Up | ➤ Sign Up | |||
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Exclusivity Expiration |
see a sample report or, see our see our flat-rate plans
Expired US Patents for diltiazem hydrochloride
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | Patent No. | Patent Expiration |
|---|---|---|---|---|---|---|---|
| Valeant Intl | CARDIZEM CD | diltiazem hydrochloride | CAPSULE, EXTENDED RELEASE;ORAL | 020062-005 | Aug 24, 1999 | ➤ Sign Up | ➤ Sign Up |
| Valeant Intl | CARDIZEM LA | diltiazem hydrochloride | TABLET, EXTENDED RELEASE;ORAL | 021392-006 | Feb 6, 2003 | ➤ Sign Up | ➤ Sign Up |
| Valeant Intl | CARDIZEM CD | diltiazem hydrochloride | CAPSULE, EXTENDED RELEASE;ORAL | 020062-002 | Dec 27, 1991 | ➤ Sign Up | ➤ Sign Up |
| Valeant Intl | CARDIZEM | diltiazem hydrochloride | TABLET;ORAL | 018602-003 | Dec 8, 1986 | ➤ Sign Up | ➤ Sign Up |
| Valeant Intl | CARDIZEM CD | diltiazem hydrochloride | CAPSULE, EXTENDED RELEASE;ORAL | 020062-003 | Dec 27, 1991 | ➤ Sign Up | ➤ Sign Up |
| Valeant Intl | CARDIZEM CD | diltiazem hydrochloride | CAPSULE, EXTENDED RELEASE;ORAL | 020062-002 | Dec 27, 1991 | ➤ Sign Up | ➤ Sign Up |
| Valeant Intl | CARDIZEM LA | diltiazem hydrochloride | TABLET, EXTENDED RELEASE;ORAL | 021392-005 | Feb 6, 2003 | ➤ Sign Up | ➤ Sign Up |
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | Patent No. | Patent Expiration |
see a sample report or, see our see our flat-rate plans
International Patents for diltiazem hydrochloride
| Country | Document Number | Estimated Expiration |
|---|---|---|
| World Intellectual Property Organization (WIPO) | 0141744 | ➤ Sign Up |
| Canada | 2348953 | ➤ Sign Up |
| Austria | 293438 | ➤ Sign Up |
| Germany | 60019550 | ➤ Sign Up |
| Austria | 430561 | ➤ Sign Up |
| Australia | 6566700 | ➤ Sign Up |
| World Intellectual Property Organization (WIPO) | 0121155 | ➤ Sign Up |
| Country | Document Number | Estimated Expiration |
For more information try a trial or see the plans and pricing
Serving hundreds of leading biopharmaceutical companies globally:
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.
Copyright 2002-2018 thinkBiotech LLC
ISSN: 2162-2639
Privacy and Cookies
Terms & Conditions
Site Map
ISSN: 2162-2639
Privacy and Cookies
Terms & Conditions
Site Map
Follow DrugPatentWatch: