DrugPatentWatch Database Preview

IBUPROFEN - Generic Drug Details

  Purchase this report

or, see our see our flat-rate plans

« Back to Dashboard

What are the generic drug sources for ibuprofen and what is the scope of ibuprofen patent protection?

Ibuprofen is the generic ingredient in forty-four branded drugs marketed by Pfizer, Amneal Pharms, Ascent Pharms Inc, Bionpharma Inc, Contract Pharmacal, Humanwell Puracap, Marksans Pharma, P And L Dev Llc, Sofgen Pharms, Strides Pharma, Bayer, Cumberland Pharms, J And J Consumer Inc, L Perrigo Co, Tris Pharma Inc, Mcneil, Wyeth Cons, Moberg Pharma North, Perrigo, Abbott, Actavis Mid Atlantic, Arise Pharms, Aurobindo Pharma Ltd, Hi-tech Pharmacal, Perrigo R And D, Taro, Mcneil Consumer, Mcneil Ped, Lederle, Basf, Alra, Pliva, Aiping Pharm Inc, Amneal Pharms Ny, Ani Pharms Inc, Aurolife Pharma Llc, Avema Pharma, Dr Reddys La, Dr Reddys Labs Inc, Granules India, Granules India Ltd, Halsey, Ivax Sub Teva Pharms, Leiner, LNK, Merro Pharm, Mylan, Mylan Pharms Inc, Northstar Hlthcare, OHM, Ohm Labs, Par Pharm, Purepac Pharm, Sandoz, Sun Pharm Industries, Superpharm, Teva, Vintage Pharms, Watson Labs, Bristol Myers, Exela Pharma Science, Recordati Rare, Pfizer Cons Hlthcare, Forest Labs, Actavis Elizabeth, Barr Labs Inc, and Dr Reddys Labs Ltd, and is included in two hundred and nine NDAs. There are fifteen patents protecting this compound. Additional information is available in the individual branded drug profile pages.

Ibuprofen has fifty-five patent family members in seventeen countries.

There are sixty-four drug master file entries for ibuprofen. Two hundred and sixty-six suppliers are listed for this compound.

Summary for IBUPROFEN

International Patents:	55
US Patents:	15
Tradenames:	44
Applicants:	67
NDAs:	209
Drug Master File Entries:	64
Suppliers / Packagers:	266
Bulk Api Vendors:	131
Clinical Trials:	524
Patent Applications:	7,287
Formulation / Manufacturing:	see details
DailyMed Link:	IBUPROFEN at DailyMed

Pharmacology for IBUPROFEN

Ingredient-type	Nonsteroidal Anti-inflammatory Compounds
Drug Class	Nonsteroidal Anti-inflammatory Drug
Mechanism of Action	Cyclooxygenase Inhibitors

Medical Subject Heading (MeSH) Categories for IBUPROFEN

Analgesics, Non-Narcotic

Anti-Inflammatory Agents, Non-Steroidal

Cyclooxygenase Inhibitors

Synonyms for IBUPROFEN

.alpha.-(4-Isobutylphenyl)propionic acid

.alpha.-(p-isobutylphenyl)propionic acid

.alpha.-2-(p-Isobutylphenyl)propionic acid

.alpha.-Methyl-4-(2-methylpropyl)benzeneacetic acid

( inverted exclamation markA)-Ibuprofen

( inverted question mark)-Ibuprofen

(? inverted exclamation markA)-2-(4-Isobutylphenyl)Propanoic Acid

(?)-Ibuprofen

(.+-.)-2-(p-Isobutylphenyl)propionic acid

(.+-.)-p-Isobutylhydratropic acid

(.+/-.)-2-(p-Isobutylphenyl)propionic acid

(.+/-.)-p-Isobutylhydratropic acid

(+-)-2-(p-Isobutylphenyl)propionic acid

(+-)-alpha-Methyl-4-(2-methylpropyl)benzeneacetic acid

(+-)-Ibuprofen

(+-)-Ibuprophen

(+-)-p-Isobutylhydratropic acid

(+) ibuprofen

(+/-)-2-(4-Isobutylphenyl)Propanoic Acid

(+/-)-2-(p-isobutylphenyl)propionic acid

(+/-)-alpha-methyl-4-(2-methylpropyl)benzeneacetic acid

(+/-)-Ibuprofen

(+/-)-p-Isobutylhydratropic acid

(4-Isobutylphenyl)-alpha-methylacetic acid

(A+/-)-Ibuprofen

(r/s)-alpha-methyl-4-isobutylphenylacetic acid

(RS)-2-(4-(2-Methylpropyl)phenyl)propanoic acid

(RS)-Ibuprofen

(S)-4-Isobutyl-alpha-methylphenylacetic acid

(y)-Ibuprofen

[(+/-)-2-(4-Isobutylphenyl)-propionic Acid

139466-08-3

15687-27-1

2-(4-Isobutyl-phenyl)-propionic acid

2-(4-isobutylphenyl) propanoic acid

2-(4-isobutylphenyl) propionic acid

2-(4-isobutylphenyl)-propionic acid

2-(4-isobutylphenyl)-propionoic acid

2-(4-Isobutylphenyl)propanoic acid

2-(4-Isobutylphenyl)propanoicAcid

2-(4-ISOBUTYLPHENYL)PROPIONIC ACID

2-(4'-isobutylphenyl)-propionic acid

2-(4'-isobutylphenyl)propionic acid

2-(p-Isobutylphenyl)propionic acid

2-[4-(2-methylpropyl)phenyl]propanoic acid

2-p-isobutylphenylpropionic acid

31121-93-4 (hydrochloride salt)

4-Isobutyl-.alpha.-methylphenylacetic acid

4-Isobutyl-alpha-methylphenylacetic acid

4-Isobutylhydratropic acid

4-Isobutylphenyl)-.alpha.-methylacetic acid

58560-75-1

687I271

79261-49-7 (potassium salt)

A831926

AB00052020_18

AB00052020_19

AB00052020-16

AB00052020-17

AB1009266

AC-11312

AC1L1GGE

AC1Q1P84

AC1Q1P85

ACHES-N-PAIN

Acide (isobutyl-4 phenyl)-2 propionique

Acide (isobutyl-4-phenyl)-2 propionique

Acide (isobutyl-4-phenyl)-2 propionique [French]

ACMC-209df0

ACMC-209ks2

Act-3

Act-3 (TN)

ACT03248

Actiprofen

Adex 200

Adran

Advil

Advil (TN)

Advil Cold & Sinus (Salt/Mix)

Advil Liqui-Gels

Advil migraine

Advil Migraine Liqui-Gels

Advil, Children's

AK-47272

Ak+C2278tren

AKOS003237488

AKOS016340658

Aktre (TN)

Aktren

Alaxan

Alaxan (TN)

ALBB-025647

Algofen

Algoflex (TN)

Alivium

Alivium (TN)

alpha-(4-isobutylphenyl)-propionic acid

alpha-(4-Isobutylphenyl)propionate

alpha-(4-Isobutylphenyl)propionic acid

alpha-(p-isobutylphenyl)-propionic acid

alpha-(p-isobutylphenyl)propionic acid

alpha-Methyl-4-(2-methylpropyl)benzeneacetic acid

alpha-Methyl-4-(isobutyl)phenylacetic acid

alpha-Methyl-4-[2-methylpropyl] benzeneacetic Acid

alpha-p-Isobutylphenylpropionate

alpha-p-Isobutylphenylpropionic acid

Am-Fam 400

AM20060782

Amelior

Amersol

Amibufen

AN-18584

Anafen

Anco

Andran

Anflagen

Antagil

Antalfene

Antarene

Antiflam

ANW-21658

Apo-Ibuprofen

Apsifen

Apsifen-F

ARONIS23835

Arthrofen (TN)

Artofen

Artril

Artril 300

Balkaprofen

Bayer Select Pain Relief

BB 0258487

BB_SC-1358

BBL010660

BDBM50009859

Benzeneacetic acid, ?-methyl-4-(2-methylpropyl)-

Benzeneacetic acid, .alpha.-methyl-4-(2-methylpropyl)-

Benzeneacetic acid, .alpha.-methyl-4-(2-methylpropyl), (.+/-.)-

Benzeneacetic acid, alpha-methyl-4-(2-methylpropyl)-

Benzeneacetic acid, alpha-methyl-4-(2-methylpropyl), (+-)-

Benzeneacetic acid, alpha-methyl-4-(2-methylpropyl), (+/-)-

Betaprofen

BIDD:GT0050

Bloom

Bluton

Bonifen (TN)

BR-47272

BRD-A17655518-001-02-0

BRN 2049713

Brofen

Brufanic

Brufen

Brufen (TN)

Brufen 400

Brufen Retard

Bruflam

Brufort

BSPBio_002170

Buburone

Bufeno

Bufigen

Bugesic (TN)

Bukrefen

Bupron

Buracaps

Burana

Burana (TN)

Butacortelone

Butylenin

C01588

C13H18O2

Caldolor

Caldolor (TN)

Calprofen (TN)

Cambridge id 5152402

Cap-Profen

Carol

CAS-15687-27-1

CBMicro_005634

CCG-38947

CCRIS 3223

CDT-ibuprofen

Cesra

CHEBI:5855

CHEMBL521

Children's Advil

CHILDREN'S ADVIL-FLAVORED

Children's Elixsure

Children's Elixsure IB

Children's Elixsure IB (Salt/Mix)

Children's Ibuprofen

Children's Motrin

Citalgan

Cobo

Codral

Codral Period Pain

Combiflam

Combunox (Salt/Mix)

CPD000058184

CS-1931

CTK3J2010

Cunil

D00126

D03SHR

D0R1QE

Daiprophen

Dalsy

Dalsy (TN)

Dansida

DB01050

Deep Relief

Dentigoa

Dibufen

Dignoflex

Dismenol (TN)

Diverin (TN)

DivK1c_000887

Dolgin

Dolgirid

Dolgit

Dolgit (TN)

Dolibu

Dolmaral

DOLO PUREN

Dolo-Dolgit

Dolo-Spedifen (TN)

Dolocyl

Dolofen

Dolofen-F

Dolofin

Dolofort

Dolofort (TN)

Dologel

Dolomax

Doloraz (TN)

Doloren

Dolormin

Dolormin (TN)

Doltibil

Dolven

Donjust B

Dorival

Dorival (TN)

DR000342

Drin

DSSTox_CID_732

DSSTox_GSID_20732

DSSTox_RID_75759

DTXSID5020732

Duafen

Dularbuprofen

Duobrus

Dura-Ibu

duralbuprofen

Dysdolen

Easifon

Ebufac

Ebufac (TN)

EC 239-784-6

EINECS 239-784-6

Emflam

Emflam-200

EmuProfen (TN)

Epitope ID:139973

Epobron

Eputex

Ergix

Espidifen (TN)

Esprenit

EU-0100691

Eve (TN)

Exneural

Faspic

Femadon

Femafen

Femapirin

Femidol

Fenbid

Fenbid (TN)

Fenbid Spansule

Fendol

Fenpaed (TN)

Fenspan

Fibraflex

Finalflex (TN)

FT-0601629

FT-0655194

Galprofen (TN)

Gelufene

Genpril

Gofen

Grefen

GTPL2713

Gynofug

Haltran

Hedex (TN)

HEFNNWSXXWATRW-UHFFFAOYSA-

HEFNNWSXXWATRW-UHFFFAOYSA-N

Hemagene Tailleur

Herron Blue (TN)

HMS1920F15

HMS2089P05

HMS2091N03

HMS2230N04

HMS3259G05

HMS3262K03

HMS3372M09

HMS3649M11

HMS3651A15

HMS502M09

HSDB 3099

HY-78131

Hydratropic acid, p-isobutyl-

I 4883

I-profen (TN)

I01-7039

I0415

IB-100

Ibalgin (TN)

Ibol

Ibren

Ibu

Ibu-Attritin

IBU-Ratiopharm (TN)

Ibu-slo

Ibu-slow

Ibu-Tab

Ibu-Tab 200

Ibu-Vivimed (TN)

Ibubest

Ibubeta

Ibucasen

Ibudol

Ibudolor

Ibufen

IBUFEN (TN)

Ibuflamar

Ibufug

Ibugel

Ibugel (TN)

Ibugen

Ibugesic

Ibuhexal

IbuHEXAL (TN)

Ibulagic

Ibular

Ibulav

Ibuleve

Ibuleve (TN)

Ibulgan

Ibum (TN)

Ibumax (TN)

Ibumed

Ibumerck

Ibumetin

Ibumetin (TN)

Ibup

Ibupirac

Ibupril

Ibuprin

Ibuprocin

Ibuprofen - Adooq Bioscience

Ibuprofen (Advil)

Ibuprofen (Dolgesic)

Ibuprofen (JP17/USP/INN)

Ibuprofen [USAN:BAN:INN:JAN]

Ibuprofen [USAN:USP:INN:BAN:JAN]

Ibuprofen 1.0 mg/ml in Methanol

Ibuprofen for peak identification, European Pharmacopoeia (EP) Reference Standard

Ibuprofen I.V. Solution

ibuprofen lysine salt

IBUPROFEN USP GRADE

Ibuprofen-Zinc

IBUPROFEN, (+-)-

Ibuprofen, >=98% (GC)

Ibuprofen, British Pharmacopoeia (BP) Reference Standard

Ibuprofen, European Pharmacopoeia (EP) Reference Standard

Ibuprofen, meets USP testing specifications

Ibuprofen, pharmaceutical secondary standard; traceable to USP, PhEur, BP

Ibuprofen, United States Pharmacopeia (USP) Reference Standard

Ibuprofen, Vetec(TM) reagent grade, 97%

Ibuprofen, VETRANAL(TM), analytical standard

Ibuprofene

Ibuprofene [INN-French]

Ibuprofeno

Ibuprofeno [INN-Spanish]

Ibuprofenum

Ibuprofenum [INN-Latin]

Ibuprohm

Ibuprom (TN)

Ibuprophen

Ibuprosyn (TN)

Ibuprox

Ibusal

Ibutid

Ibux

Ibux (TN)

Ibuxin (TN)

IDI1_000887

Ifen

Inabrin

InChI=1/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15)

Inflam

Inoven

IP 82

IP-82

IP82

Ipren

Ipren (TN)

Irfen

Isobutylpropanoicphenolic acid

Isodol

J-009349

J10135

Jenaprofen

Junifen

Junior Strength Advil

Junior Strength Ibuprofen

Junior Strength Motrin

KB-222912

KBio1_000887

KBio2_001329

KBio2_003897

KBio2_006465

KBio3_001390

KBioGR_000389

KBioSS_001329

Kesan

Kontagripp Mono

Kratalgin

Kratalgin (TN)

KS-00000CJ0

KS-000047NV

KS-5029

KSC492A1B

Lamidon

Lebrufen

Librofem

Lidifen

Liptan

Lopac0_000691

Lopane

LP00691

LS-7454

M-4957

Malafene

Manypren

MCULE-9475454445

Medicol (TN)

Medipren

Melfen

Mensoton

MFCD00010393

Midol

Midol 200

Midol IB Cramp Relief

Midol Liquid Gels

MLS000069733

MLS001146965

MolPort-001-791-802

Moment

Moment (TN)

Motrin

Motrin (TN)

Motrin IB

Motrin IB Gelcaps

Motrin IB Gelcaps (Salt/Mix)

MOTRIN MIGRAINE PAIN

Mynosedin

N4,N4' -Di(naphthalen-1-yl)-N4,N4' -bis(4-vinylphenyl)biphenyl-4,4'-diamine

Nagifen-D

Napacetin

Narfen

Narfen (TN)

NC00458

NCGC00015529-04

NCGC00015529-05

NCGC00015529-06

NCGC00015529-07

NCGC00015529-08

NCGC00015529-09

NCGC00015529-10

NCGC00015529-12

NCGC00015529-13

NCGC00015529-14

NCGC00015529-15

NCGC00015529-18

NCGC00089819-02

NCGC00089819-03

NCGC00089819-04

NCGC00089819-05

NCGC00089819-06

NCGC00089819-07

NCGC00256416-01

NCGC00258935-01

NCGC00261376-01

NCI60_002065

Neo-Helvagit

Neo-Mindol

Neobrufen

Neobrufen (TN)

Neofen (TN)

Nerofen

NINDS_000887

Noalgil

Nobafon

Nobfelon

Nobfen

Nobgen

Noritis

Norton

Norvectan (TN)

Novadol

Novo Dioxadol

Novo-Profen

Novogent

Novogent N

Novoprofen

NSC 256857

NSC-256857

NSC-757073

NSC256857

NSC757073

Nuprilan

Nuprin

Nuprin (TN)

Nureflex (TN)

Nurofen

Nurofen (TN)

Nurofen Meltlets

Opera_ID_554

Optifen

Opturem

OR209164

OR289785

Oralfene

Orbifen (TN)

Ostarin

Ostofen

Ozonol

p-Isobutyl-2-phenylpropionate

p-Isobutyl-2-phenylpropionic acid

p-isobutyl-hydratropic acid

p-Isobutylhydratropate

p-Isobutylhydratropic acid

Paduden

Panafen

Panafen (TN)

Pantrop

Para-Isobutylhydratropic Acid

Paxofen

Pedea

Pedia-Profen

PediaProfen

Pediatric Advil

Perifar (TN)

Perofen

Perrigo ibuprofen

Pharmakon1600-01500347

Proartinal

Profen

Profin (TN)

Proflex

Propanoic acid, 2-(4-isobutylphenyl)

Provon

PubChem16054

Quadrax

R.D. 13621

Racemic ibuprofen

Rafen

Ranofen

Ratiodolor (TN)

RD 13621

Rebugen

Relcofen

Retard (TN)

Rhinadvil

Rimafen (TN)

Rofen

Roidenin

RP26239

RTR-006580

Rufen

Rufin

Rupan

s1638

Sadefen

Salivia

Salprofen

Salvarina (TN)

SAM002264619

SBB064160

SBI-0050669.P004

SC-18867

SCHEMBL3001

Schmerz-Dolgit

Seclodin

Sednafen

Seklodin

Seskafen

Sine-Aid IB Caplets (Salt/Mix)

Siyafen

SMR000058184

Solpaflex

Solpaflex (TN)

Solufen

SPBio_000178

Spectrum_000849

SPECTRUM1500347

Spectrum2_000129

Spectrum3_000465

Spectrum4_000015

Spectrum5_000862

Spedifen (TN)

Speedpain NANO (TN)

Spidifen (TN)

SR-01000000214

SR-01000000214-13

SR-01000000214-2

ST-1482

ST024750

ST24032335

Stelar

STK177358

Sugafen

Suprafen

Suspren

Syntofene

Tab-Profen

Tabalon

Tabalon 400

Tatanal

Tempil

TL8001184

Tofen

Togal N

Tonal

Tox21_110170

Tox21_110170_1

Tox21_201384

Tox21_302829

Tox21_500691

TR-006580

TRA0047278

Trauma-Dolgit Gel

Trendar

U 18573

U-18,573

U-18573

UCB 79171

Unipron

Upfen

Upfen (TN)

Uprofen

Urem

VUFB 9649

WLN: QVY&R DIY

Z1695709473

Zafen

ZAG-1701

Zofen

US Patents and Regulatory Information for IBUPROFEN

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Exclusivity Expiration
Mcneil	IBUPROFEN	ibuprofen	TABLET;ORAL	070476-001	Jun 16, 1986		DISCN	No	No
Watson Labs	IBUPROFEN	ibuprofen	TABLET;ORAL	071547-001	Jul 2, 1987		DISCN	No	No
Aiping Pharm Inc	IBUPROFEN	ibuprofen	TABLET;ORAL	202413-002	Nov 23, 2016	AB	RX	No	No
Ohm Labs	IBUPROHM COLD AND SINUS	ibuprofen; pseudoephedrine hydrochloride	TABLET;ORAL	074567-001	Apr 17, 2001		OTC	No	No

  Purchase this report

or, see our see our flat-rate plans

Expired US Patents for IBUPROFEN

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	Patent No.	Patent Expiration
J And J Consumer Inc	CHILDREN'S MOTRIN	ibuprofen	SUSPENSION;ORAL	020516-001	Jun 16, 1995
J And J Consumer Inc	CHILDREN'S MOTRIN	ibuprofen	TABLET, CHEWABLE;ORAL	020601-001	Nov 15, 1996
J And J Consumer Inc	JUNIOR STRENGTH MOTRIN	ibuprofen	TABLET, CHEWABLE;ORAL	020601-003	Nov 15, 1996
J And J Consumer Inc	CHILDREN'S MOTRIN	ibuprofen	SUSPENSION/DROPS;ORAL	020603-001	Jun 10, 1996

  Purchase this report

or, see our see our flat-rate plans

International Patents for IBUPROFEN

Country	Document Number	Estimated Expiration
Japan	2012523377
Australia	2010274030
Canada	2754922
South Korea	20140014350