Last Updated: June 24, 2026

MIDOL LIQUID GELS Drug Patent Profile


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When do Midol Liquid Gels patents expire, and what generic alternatives are available?

Midol Liquid Gels is a drug marketed by Bionpharma and is included in one NDA.

The generic ingredient in MIDOL LIQUID GELS is ibuprofen. There are sixty-four drug master file entries for this compound. Two hundred and forty-four suppliers are listed for this compound. Additional details are available on the ibuprofen profile page.

DrugPatentWatch® Litigation and Generic Entry Outlook for Midol Liquid Gels

A generic version of MIDOL LIQUID GELS was approved as ibuprofen by CONTRACT PHARMACAL on October 15th, 1986.

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Summary for MIDOL LIQUID GELS
Recent Clinical Trials for MIDOL LIQUID GELS

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SponsorPhase
Gary Van GuilderEARLY_PHASE1
Rutgers, The State University of New JerseyPHASE1
Sakarya UniversityNA

See all MIDOL LIQUID GELS clinical trials

US Patents and Regulatory Information for MIDOL LIQUID GELS

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Bionpharma MIDOL LIQUID GELS ibuprofen CAPSULE;ORAL 021472-001 Oct 18, 2002 OTC Yes Yes ⤷  Start Trial ⤷  Start Trial ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

EU/EMA Drug Approvals for MIDOL LIQUID GELS

Company Drugname Inn Product Number / Indication Status Generic Biosimilar Orphan Marketing Authorisation Marketing Refusal
Recordati Rare Diseases Pedea ibuprofen EMEA/H/C/000549Treatment of a haemodynamically significant patent ductus arteriosus in preterm newborn infants less than 34 weeks of gestational age. Authorised no no no 2004-07-28
>Company >Drugname >Inn >Product Number / Indication >Status >Generic >Biosimilar >Orphan >Marketing Authorisation >Marketing Refusal

International Patents for MIDOL LIQUID GELS

See the table below for patents covering MIDOL LIQUID GELS around the world.

Country Patent Number Title Estimated Expiration
Austria 357229 ⤷  Start Trial
Australia 7094900 ⤷  Start Trial
Australia 780212 ⤷  Start Trial
Canada 2382292 GELS MOUS CONTENANT DE L'IBUPROFENE (IBUPROFEN-CONTAINING SOFTGELS) ⤷  Start Trial
Germany 60034044 ⤷  Start Trial
>Country >Patent Number >Title >Estimated Expiration

Supplementary Protection Certificates for MIDOL LIQUID GELS

Patent Number Supplementary Protection Certificate SPC Country SPC Expiration SPC Description
1781277 PA2024501 Lithuania ⤷  Start Trial PRODUCT NAME: IBUPROFENO IR PARACETAMOLIO DERINYS; REGISTRATION NO/DATE: LT/1/23/5212/001-002 20230726
>Patent Number >Supplementary Protection Certificate >SPC Country >SPC Expiration >SPC Description

Midol Liquid Gels Market Dynamics and Financial Trajectory (2024–2026): Pricing, Share Drivers, and IP/Competition Risks

Last updated: June 8, 2026

Executive summary: Midol Liquid Gels is a low-to-mid price, OTC pain-and-menstrual symptom product where demand is driven by seasonal menstruation cycles, retailer planograms, promo intensity, and formulation-level substitution across competing OTC brands. The category is capacity- and inventory-sensitive around peak months, with margin performance tied to trade terms and promotional cadence rather than patent-led price hold. Because Midol is an OTC brand and “Liquid Gels” is a product format within the Midol line, the relevant dynamics are brand and channel execution plus regulatory/compliance costs, not long-lived exclusivity. Financial trajectory is therefore most plausibly characterized as steady brand-revenue generation with volatility from promotional spend, retailer delistings, and substitute launches in the same OTC segment.


How does the Midol Liquid Gels market perform seasonally and by channel?

Featured snippet answer: Midol Liquid Gels demand tracks menstruation seasonality with peak purchasing in the weeks leading into and during late winter through spring and again into summer-to-back-to-school periods, while channel revenue is typically split between mass and drugstore chains with outsized impact from seasonal endcaps and “event” promotions.

Seasonality patterns

OTC menstrual pain and related symptomatic relief products show demand concentration around predictable consumer purchasing windows:

  • Retail calendars: promotions typically cluster around peak holiday disruption periods and back-to-school seasonality, when shoppers restock OTC symptom relief.
  • Inventory cycles: retailers front-load inventory ahead of peak weeks; sell-through then drives replenishment and promotional intensity.

Channel dynamics

For Midol-branded OTC analgesic formats, channel economics typically hinge on:

  • Mass retailers and club stores: higher volume, lower net price; heavy reliance on trade spend and planogram compliance.
  • Drugstores (pharmacy chains): more frequent SKU-level substitution, stronger role for brand equity and shelf visibility.
  • E-commerce: incremental sales often follow price competitiveness and subscription or bundle behavior; promo-driven supply allocation affects availability.

What matters most for revenue growth

Midol Liquid Gels growth is typically strongest when three operational levers align:

  • Shelf presence: consistent “Liquid Gels” facings and adjacency to competing menstrual OTC formats.
  • Promo timing: price/multibuy offers aligned to peak symptom incidence.
  • Substitution control: convincing differentiation versus tablet, caplet, and alternative “fast relief” formats inside the same OTC analgesic segment.

What pricing and gross margin dynamics drive Midol Liquid Gels profitability?

Featured snippet answer: Midol Liquid Gels profitability is driven by net price after trade terms and promo, not by unit cost alone. Promotional intensity and retailer mix determine the margin swing year-to-year.

Net price drivers (OTC brand model)

  • Retailer trade spend: slotting, category management, and incremental shelf promotion reduce gross-to-net.
  • Promotional depth: mass retailers frequently compress net pricing during high-volume periods.
  • Mix shift between formats: Liquid Gels can outperform tablets/caplets when “fast-acting” or “gentler” claims resonate, but that depends on retail promotion strategy.

Cost structure

OTC brand profitability is usually affected by:

  • Manufacturing throughput and packaging costs: “liquid gel” manufacturing is cost-sensitive to raw material volatility and packaging grade.
  • Quality/compliance: GMP and post-market surveillance costs scale with SKU complexity.
  • Trade and logistics: seasonal demand spikes increase distribution inefficiency risk.

Financial trajectory implication

Absent a patent-protected premium pricing regime (OTC brand context), the long-run direction of profits tends to follow:

  • Brand health and velocity: if Liquid Gels retain share during peak periods, the company can sustain higher net pricing.
  • Promo spend discipline: if promotional intensity increases, revenue can remain stable while operating margin compresses.

How competitive is the Midol Liquid Gels space versus other OTC menstrual pain products?

Featured snippet answer: Competition is dominated by OTC analgesic brands and private label across “menstrual pain relief” and adjacent “period cramps” symptom segments, with substitution primarily driven by perceived speed of relief, pill format preference, and retailer promotion.

Key substitute vectors

  • Formulation/format: caplets/tablets vs liquid gels; capsule familiarity reduces friction for some shoppers.
  • Perceived onset: “fast relief” positioning can shift preference even when active ingredient logic overlaps.
  • Retailer brand ecosystems: private label often undercuts on price during promo windows.

Competitive landscape structure

The competitive set typically falls into:

  • Brand-to-brand competition within the menstrual symptom shelf
  • Private label substitution under retailer house brands
  • Cross-category substitution from general OTC pain products used off-label for menstrual discomfort (depending on consumer behavior and labeling familiarity)

How competition changes financial outcomes

When competitors increase promotion or add similar “quick relief” SKUs:

  • Midol Liquid Gels net price declines
  • Marketing and trade spend rises to defend share
  • Gross margin compresses
  • Operating income becomes promo-driven rather than volume-driven

What patents protect Midol Liquid Gels, and how does that affect exclusivity and pricing?

Featured snippet answer: Midol Liquid Gels is an OTC product, so pricing power is largely brand- and channel-based rather than enforceable “in-use” exclusivity from a robust patent estate. Any remaining IP relevance typically comes from formulation and method patents that are not equivalent to Rx-style long exclusivity.

OTC reality check for exclusivity

  • OTC products commonly face earlier generic entry or compounding competition depending on active ingredient and dosage form history.
  • For “Liquid Gels,” differentiation can be tied to formulation/process claims, but practical pricing depends more on brand equity and retailer assortment.

Patent estate relevance for the financial trajectory

Where patent coverage exists and is enforced:

  • it can slow direct format-copying and support a premium; where it is weak or non-exclusivity dominated:
  • the financial trajectory is shaped by retailer selection and promotional cadence.

No verified, specific patent numbers, assignees, or expiration dates for “MIDOL LIQUID GELS” are provided in the available source set for this response.


When does Midol Liquid Gels lose exclusivity, and does that create a generic entry risk?

Featured snippet answer: The practical generic entry risk for Midol Liquid Gels is tied to whether regulators and manufacturers can lawfully market alternative equivalents in the same OTC segment; exclusivity timelines for a specific OTC “Liquid Gels” SKU typically do not create a single, discrete “loss” event comparable to Hatch-Waxman Rx exclusivity.

Generic entry mechanics in OTC segments

  • Regulatory pathway and labeling equivalence determine whether an alternative product can replace Midol’s share.
  • Shelf acceptance and retailer procurement often determine whether a “legal generic” becomes a commercial threat.
  • Price elasticity in OTC menstrual pain categories is generally high, so replacement can be rapid if retailer support shifts.

Implication for financial trajectory

  • Near-term financial performance is more likely to be challenged by promo and assortment shifts than by a single “patent cliff.”
  • A sharp revenue drop is more plausible if Midol’s listing status is reduced or if competitors gain front-of-shelf positions with aggressive pricing.

No verified Orange Book listing, FDA exclusivity record, or specific patent expiration timetable for “Midol Liquid Gels” is included in the available source set for this response.


What is the FDA and Orange Book status of Midol Liquid Gels?

Featured snippet answer: As an OTC product, Midol Liquid Gels is not managed under the same Orange Book exclusivity framework as an Rx NDA/BLA, so the most relevant regulatory footprint for “market access” is OTC monograph compliance and labeling rules rather than Orange Book listings.

What this means for competitive entry

  • If compliant with OTC regulations and labeling requirements, products can enter as alternatives even without patent-driven barriers.
  • Brand differentiation is protected most effectively through formulation IP enforcement (if any) and trademark/brand equity, not exclusivity listings.

No verified FDA Orange Book entries for “Midol Liquid Gels” are included in the available source set for this response.


How do formulations and dosage form choices affect substitution and earnings?

Featured snippet answer: Switching between dosage forms (liquid gels vs caplets/tablets) impacts consumer preference and retailer positioning more than it changes fundamental category demand. Earnings are therefore sensitive to whether the brand maintains the “format preference” advantage during peak months.

Liquid gels as a commercial lever

Liquid gels can win share when consumers perceive:

  • easier swallowing
  • faster onset
  • better tolerance or comfort Retailers can convert that perception into higher turnover by placing liquid gels in key high-traffic planogram locations.

Formulation-related cost and stability

Liquid gel manufacturing adds:

  • packaging specifications
  • fill accuracy and viscosity control
  • higher QA intensity for gel integrity

Earnings sensitivity

  • If input costs rise faster than the brand can pass them via net price, margin compresses.
  • If promotional intensity rises to defend shelf, margin compresses further.

What patent litigation, Paragraph IV challenges, or settlements affect Midol Liquid Gels?

Featured snippet answer: No verified patent litigation record, Paragraph IV challenges, or settlement details for “Midol Liquid Gels” are available in the provided source set for this response.

Why Rx-style litigation frameworks may not apply

Paragraph IV and Hatch-Waxman litigation typically attaches to Rx ANDAs with Orange Book-listed patents. For an OTC brand product line, disputes tend to be less frequent and more often focus on:

  • trademark/labeling
  • formulation/IP claims
  • regulatory compliance or enforcement

No verified litigation docket references are included in the available source set for this response.


How do licensing and manufacturing scale influence Midol Liquid Gels financial trajectory?

Featured snippet answer: For OTC brands, financial trajectory depends on manufacturing scale stability, supply chain reliability, and trade terms that influence net price. Licensing and toll manufacturing can help smooth supply risk but can compress margins if reliance increases.

Supply chain factors

  • seasonal demand spikes
  • packaging lead times
  • gel-formulation stability
  • distribution throughput

Manufacturing/IP barriers

Even when formulation IP exists, the biggest barrier in practice is:

  • whether contract manufacturers can produce reliably to brand specifications
  • whether retailers accept the product under comparable terms

Company and revenue exposure: what portion of Midol’s business depends on Liquid Gels?

Featured snippet answer: Liquid Gels is a format within the Midol brand portfolio; its revenue exposure is significant during peak menstrual symptom seasons but typically does not drive the full enterprise revenue line. The revenue sensitivity is concentrated around assortment decisions and promotional calendars.

No verified segment reporting that isolates “Midol Liquid Gels” revenues is included in the available source set for this response.


Key Takeaways

  • Midol Liquid Gels is a seasonal, OTC brand product where revenue and profit are driven primarily by promo intensity, retailer shelf execution, and format substitution dynamics.
  • Unlike Rx products, the financial trajectory is not dominated by a single exclusivity timeline or Paragraph IV-style generic entry cliff.
  • The most meaningful downside risks to financial performance are delisting, reduced facings, promo escalation by competitors, and net price compression.
  • The main upside lever is maintaining Liquid Gels “format preference” and winning peak-season planogram placements that sustain sell-through and reduce reliance on deep discounting.

FAQs

  1. What retail promo calendars matter most for Midol Liquid Gels sell-through?
  2. How does substitution from tablets/caplets to liquid gels change Midol’s unit economics?
  3. What OTC competitors typically pressure net pricing in period-cramp relief categories?
  4. How do supply disruptions around gel filling or packaging affect seasonal revenue?
  5. What regulatory or labeling changes most often impact menstrual symptom OTC brands?

References (APA)

  1. No cited sources were provided in the available source set for this response.

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