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Generated: March 20, 2019

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Spironolactone - Generic Drug Details

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What are the generic sources for spironolactone and what is the scope of spironolactone freedom to operate?

Spironolactone is the generic ingredient in three branded drugs marketed by Cmp Dev Llc, Gd Searle Llc, Accord Hlthcare, Actavis Elizabeth, Amneal Pharms, Ascot, Aurobindo Pharma Ltd, Casi Pharms Inc, Ivax Pharms, Jubilant Generics, Lederle, Mutual Pharm, Mylan, Oxford Pharms, Purepac Pharm, Sun Pharm Industries, Superpharm, Upsher Smith, Vangard, Warner Chilcott, Watson Labs, and Zydus Pharms Usa Inc, and is included in twenty-five NDAs. There is one patent protecting this compound. Additional information is available in the individual branded drug profile pages.

Spironolactone has one patent family member in one country.

There are sixteen drug master file entries for spironolactone. Fifty-one suppliers are listed for this compound.

Pharmacology for spironolactone
Medical Subject Heading (MeSH) Categories for spironolactone
Synonyms for spironolactone
(1'S,2R,2'R,9'R,10'R,11'S,15'S)-9'-(acetylsulfanyl)-2',15'-dimethylspiro[oxolane-2,14'-tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan]-6'-ene-5,5'-dione
(1'S,2R,2'R,9'R,10'R,11'S,15'S)-9'-(acetylsulfanyl)-2',15'-dimethylspiro[oxolane-2,14'-tetracyclo[8.7.0.0;{2,7}.0;{11,15}]heptadecan]-6'-ene-5,5'-dione
(7?,17?)-7-(Acetylthio)-17-hydroxy-3-oxopregn-4-ene-21-carboxylic acid ?-lactone
082S250
1050678-93-7
1436392-20-9
17-alpha-Pregn-4-ene-21-carboxylic acid, 17-hydroxy-7-alpha-mercapto-3-oxo-, gamma-lactone acetate
17-HYDROXY-7ALPHA-MERCAPTO-3-OXO-17ALPHA-PREGN-4-ENE-21- CARBOXYLIC ACID
17-HYDROXY-7ALPHA-MERCAPTO-3-OXO-17ALPHA-PREGN-4-ENE-21- CARBOXYLIC ACID, GAMMA-LACTONE ACETATE
17-Hydroxy-7alpha-mercapto-3-oxo-17alpha-pregn-4-ene-21-carboxylic acid, gamma-lactone acetate
17.alpha.-Pregn-4-ene-21-carboxylic acid, .gamma.-lactone acetate
17.alpha.-Pregn-4-ene-21-carboxylic acid, .gamma.-lactone, acetate
17alpha-Pregn-4-ene-21-carboxylic acid, 17-hydroxy-7alpha-mercapto-3-oxo-, gamma-lactone, acetate
2'',15''-dimethyl-5,5''-dioxo-(9''R)-spiro[tetrahydrofuran-2,14''-tetracyclo[8.7.0.02,7.011,15]heptadec-6''-ene]-9-yl ethanethioate
2'',15''-dimethyl-5,5''-dioxospiro[tetrahydrofuran-2,14''-tetracyclo[8.7.0.02,7.011,15]heptadec-6''-ene]-9-yl ethanethioate
2'',15''-dimethyl-5,5''-dioxospiro[tetrahydrofuran-2,14''-tetracyclo[8.7.0.02,7.011,15]heptadec-6''-ene]-9-yl ethanethioate(Spiranolactone)
27O7W4T232
2oax
3-(3-Keto-7-alpha-acetylthio-17-beta-hydroxy-4-androsten-17-alpha-yl)propionic acid lactone
3-(3-Keto-7.alpha.-acetylthio-17.beta.-hydroxy-4-androsten-17.alpha.-yl)propionic acid lactone
3'-(3-Oxo-7-alpha-acetylthio-17-beta-hydroxyandrost-4-en-17-beta-yl)propionic acid lactone
3vhu
4-18-00-01601 (Beilstein Handbook Reference)
4-Pregnen-21-oic acid-17|A-ol-3-one-7|A-thiol |A-lactone 7-acetate; 7|A-(Acetylthio)-17|A-hydroxy-3-oxopregn-4-ene-21-carboxylic acid |A-lactone
4-Pregnen-21-oic acid-17alpha-ol-3-one-7alpha-thiol gamma-lactone 7-acetate
496916-40-6
52-01-7
7-.alpha.-(acetylthio)-17-.alpha.-hydroxy-3-oxopregn-4-ene-21-carboxylic acid, .gamma.-lactone
7-alpha-(acetylthio)-17-alpha-hydroxy-3-oxopregn-4-ene-21-carboxylic acid, gamma-lactone
7-alpha-(acetylthio)-17-alpha-hydroxy-3-oxopregn-4-ene-21-carboxylic acid, gamma-lactone (9CI)
7-alpha-Acetylthio-3-oxo-17-alpha-pregn-4-ene-21,17-beta-carbolactone
7080-EP2269989A1
7080-EP2270011A1
7080-EP2272841A1
7080-EP2295406A1
7080-EP2298772A1
7080-EP2298776A1
7080-EP2301936A1
7080-EP2308562A2
7080-EP2308839A1
7alpha-(acetylsulfanyl)-3-oxo-17alpha-pregn-4-ene-21,17-carbolactone
7alpha-(Acetylthio)-17alpha-hydroxy-3-oxopregn-4-ene-21-carboxylic acid gamma-lactone
AB00513806
AB01275520_02
AB01275520-01
AB1009415
Abbolactone
AC-4214
AC1L1L8Q
Acelat
ACT02596
AK546740
AKOS015896401
Aldace
Aldactide
Aldactone
Aldactone (TN)
Aldactone A
Alderon
Aldopur
Almatol
Altex
Aquareduct
BC204094
BDBM50228080
Berlactone
BIDD:PXR0071
BPBio1_000194
BRD-K90027355-001-03-4
BRD-K90027355-001-19-0
BRN 0057767
BSPBio_000176
C07310
C24H32O4S
Carospir
CAS-52-01-7
CCG-220128
CHEBI:9241
CHEMBL1393
CPD000471892
CS-2670
D00443
DB00421
Deverol
Diatense
Diatensec
Dira
DSSTox_CID_14186
DSSTox_GSID_34186
DSSTox_RID_79120
DTXSID6034186
Duraspiron
EINECS 200-133-6
EN300-123035
Espironolactona
Espironolactona [INN-Spanish]
Euteberol
GAMMA-LACTONE ACETATE
GTPL2875
H490
HMS1568I18
HMS2090N21
HMS2095I18
HMS2236E06
HMS3259G11
HMS3712I18
HSDB 3184
HY-B0561
I06-1970
KS-00000FA6
KS-5234
Lacalmin
Lacdene
Laractone
LS-118614
LXMSZDCAJNLERA-ZHYRCANASA-N
MCULE-4394091100
Melarcon
MFCD00082250
MLS001074672
MLS001333253
MLS001333254
MLS002153245
MLS002207058
MLS002548846
MolPort-033-355-721
NC00482
NCGC00015948-02
NCGC00164397-01
NCGC00164397-02
NCGC00164397-03
NCGC00164397-05
NCGC00255229-01
Nefurofan
NSC 150399
NSC-150399
NSC150399
Osyrol
Pregn-4-ene-21-carboxylic acid, .gamma.-lactone, (7.alpha.,17.alpha.)-
Pregn-4-ene-21-carboxylic acid, 7-(acetylthio)-17-hydroxy-3-oxo-, gamma-lactone, (7alpha,17alpha)-
Prestwick0_000128
Prestwick1_000128
Prestwick2_000128
Prestwick3_000128
Q-201737
S-((7R,8R,9S,10R,13S,14S,17R)-10,13-dimethyl-3,5'-dioxo-1,2,3,4',5',6,7,8,9,10,11,12,13,14,15,16-hexadecahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-7-yl) ethanethioate
S-(2''R,7R,8R,9S,10R,13S,14S)-10,13-dimethyl-3,5''-dioxo-1,2,3,4'',5'',6,7,8,9,10,11,12,13,14,15,16-hexadecahydro-3''H-spiro[cyclopenta[a]phenanthrene-17,2''-furan]-7-yl ethanethioate
S-[(7R,8R,9S,10R,13S,14S,17R)-10,13-dimethyl-3,5'-dioxo-1,2,3,4',5',6,7,8,9,10,11,12,13,14,15,16-hexadecahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-7-yl] ethanethioate
S-[(7R,8R,9S,10R,13S,14S,17R)-10,13-dimethyl-3,5'-dioxospiro[2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-17,2'-oxolane]-7-yl] ethanethioate
S0260
s4054
Sagisal
SC 15983
SC 9420
SC-15112
SC-9420
SCHEMBL20939
Sincomen
SMR000471892
SNL
SPBio_002115
Spiractin
Spiranolactone
Spiresis
Spiretic
Spiridon
Spiro-Tablinen
Spiro(17H-cyclopenta(a)phenanthrene-17,2'(5'H)-furan), pregn-4-ene-21-carboxylic acid deriv
Spiro(17H-cyclopenta(a)phenauthrene-17,2'-(3'H)-furan)
Spiro[17H-cyclopenta[a]phenauthrene-17,2'-(3'H)-furan]
Spiroctan
Spiroctanie
Spiroderm
Spirolactone
Spirolakton
Spirolang
Spirolone
Spirone
Spironocompren
Spironolactone (JP17/USP/INN)
Spironolactone [BAN:INN:JAN]
Spironolactone [INN:BAN:JAN]
Spironolactone [USP:INN:BAN:JAN]
Spironolactone 1.0 mg/ml in Acetonitrile
Spironolactone A
Spironolactone for system suitability, European Pharmacopoeia (EP) Reference Standard
Spironolactone, 97.0-103.0%
Spironolactone, 99%
Spironolactone, European Pharmacopoeia (EP) Reference Standard
Spironolactone, United States Pharmacopeia (USP) Reference Standard
Spironolactonum
Spironolactonum [INN-Latin]
spironolattone
Spironolattone [DCIT]
spirotone
Sprioderm
SR-01000765419
SR-01000765419-2
SR-05000000452
SR-05000000452-2
Supra-puren
Suracton
Tox21_113047
Tox21_302154
UNII-27O7W4T232
Uractone
Urusonin
Veroshpiron
Verospiron
Verospirone
Verospirone Opianin
WLN: L E5 B666 FX OV MUTJ A1 E1 KSV1 F-& CT5VOXTJ
Xenalon
Z1551900341
ZINC3861599

US Patents and Regulatory Information for spironolactone

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Warner Chilcott SPIRONOLACTONE spironolactone TABLET;ORAL 087952-001 Nov 18, 1982 DISCN No No ➤ Try a Free Trial ➤ Try a Free Trial ➤ Try a Free Trial
Mylan SPIRONOLACTONE spironolactone TABLET;ORAL 040424-003 Aug 20, 2001 AB RX No No ➤ Try a Free Trial ➤ Try a Free Trial ➤ Try a Free Trial
Actavis Elizabeth SPIRONOLACTONE spironolactone TABLET;ORAL 040353-002 Jul 29, 1999 AB RX No No ➤ Try a Free Trial ➤ Try a Free Trial ➤ Try a Free Trial
Actavis Elizabeth SPIRONOLACTONE spironolactone TABLET;ORAL 040353-001 Jul 29, 1999 AB RX No No ➤ Try a Free Trial ➤ Try a Free Trial ➤ Try a Free Trial
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration

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