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Lisinopril - Generic Drug Details
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What are the generic drug sources for lisinopril and what is the scope of lisinopril freedom to operate?
Lisinopril
is the generic ingredient in four branded drugs marketed by Silvergate Pharms, Accord Hlthcare, Apotex Inc, Aurobindo, Casi Pharms Inc, Hikma Intl Pharms, Invagen Pharms, Ivax Sub Teva Pharms, Lupin, Mylan, Prinston Inc, Sandoz, Sun Pharm Inds Ltd, Teva, Watson Labs, Wockhardt, Merck, and Alvogen Malta, and is included in twenty-one NDAs. There are three patents protecting this compound. Additional information is available in the individual branded drug profile pages.Lisinopril has one patent family member in one country.
There are twenty-one drug master file entries for lisinopril. Eighty suppliers are listed for this compound.
Summary for lisinopril
| International Patents: | 1 |
| US Patents: | 3 |
| Tradenames: | 4 |
| Applicants: | 18 |
| NDAs: | 21 |
| Drug Master File Entries: | 21 |
| Suppliers / Packagers: | 80 |
| Bulk Api Vendors: | 57 |
| Clinical Trials: | 94 |
| Patent Applications: | 6,462 |
| Formulation / Manufacturing: | see details |
| Drug Prices: | Drug price information for lisinopril |
| Patent Litigation and PTAB cases: | See patent lawsuits and PTAB cases for lisinopril |
| DailyMed Link: | lisinopril at DailyMed |
Pharmacology for lisinopril
| Drug Class | Angiotensin Converting Enzyme Inhibitor |
| Mechanism of Action | Angiotensin-converting Enzyme Inhibitors |
Medical Subject Heading (MeSH) Categories for lisinopril
Synonyms for lisinopril
| (2S)-1-[(2S)-6-amino-2-[[(1S)-1-carboxy-3-phenyl-propyl]amino]hexanoyl]proline;hydrate |
| (2S)-1-[(2S)-6-amino-2-[[(1S)-1-carboxy-3-phenyl-propyl]amino]hexanoyl]pyrrolidine-2-carboxylic acid |
| (2S)-1-[(2S)-6-amino-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]-1-oxohexyl]-2-pyrrolidinecarboxylic acid |
| (2S)-1-[(2S)-6-amino-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]-1-oxohexyl]-2-pyrrolidinecarboxylic acid;hydrate |
| (2S)-1-[(2S)-6-amino-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]hexanoyl]pyrrolidine-2-carboxylic acid;hydrate |
| (2S)-1-[(2S)-6-amino-2-[[(2S)-1-hydroxy-1-oxo-4-phenylbutan-2-yl]amino]hexanoyl]pyrrolidine-2-carboxylic acid |
| (2S)-1-[(2S)-6-amino-2-{[(1S)-1-carboxy-3-phenylpropyl]amino}hexanoyl]pyrrolidine-2-carboxylic acid |
| (2S)-1-[(2S)-6-azanyl-2-[[(2S)-1-oxidanyl-1-oxidanylidene-4-phenyl-butan-2-yl]amino]hexanoyl]pyrrolidine-2-carboxylic acid |
| (2S)-1-[(2S)-6-azanyl-2-[[(2S)-1-oxidanyl-1-oxidanylidene-4-phenyl-butan-2-yl]amino]hexanoyl]pyrrolidine-2-carboxylic acid;hydrate |
| (S)-1-((S)-6-Amino-2-(((S)-1-carboxy-3-phenylpropyl)amino)hexanoyl)pyrrolidine-2-carboxylic acid |
| (S)-1-(N(2)-(1-carboxy-3-phenylpropyl)-L-lysyl)-L-proline |
| (S)-1-(N(sup 2)-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline |
| (S)-1-(N2-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline |
| (S)-1-(N2-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline dihydrate |
| (S)-1-[(S)-6-AMINO-2-((S)-1-CARBOXY-3-PHENYL-PROPYLAMINO)-HEXANOYL]-PYRROLIDINE-2-CARBOXYLIC ACID |
| (S)-1-[N2-(1-carboxy-3-phenylpropyl)-L-lysyl]-L-proline dihydrate |
| (S)-1-[N2-(1-Carboxy-3-phenylpropyl)-lysyl-proline dihydrate |
| (S)-NALPHA-(1-CARBOXY-3-PHENYLPROPYL)-LYS-PRO |
| [N2-[(S)-1-CARBOXY-3-PHENYLPROPYL]-L-LYSYL-L-PROLINE |
| 1-(N2-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline |
| 1-[Nalpha-[(S)-1-Carboxy-3-phenylpropyl]-L-lysyl]-L-proline |
| 1835AH |
| 2517AH |
| 54256-EP2270011A1 |
| 54256-EP2272834A1 |
| 54256-EP2277879A1 |
| 54256-EP2287165A2 |
| 54256-EP2287166A2 |
| 54256-EP2292228A1 |
| 54256-EP2292620A2 |
| 54256-EP2298742A1 |
| 54256-EP2298776A1 |
| 54256-EP2298779A1 |
| 54256-EP2301923A1 |
| 54256-EP2301929A1 |
| 54256-EP2301931A1 |
| 54256-EP2301935A1 |
| 54256-EP2305648A1 |
| 54256-EP2305674A1 |
| 54256-EP2308562A2 |
| 547L983 |
| 76547-98-3 |
| 77726-95-5 |
| 7Q3P4BS2FD |
| 83915-83-7 |
| 83915-83-7 (Parent) |
| A838743 |
| AB00052250_14 |
| AB00052250_15 |
| AB00052250-13 |
| AB04852 |
| AC1NSFPF |
| Acerbon |
| Acercomp |
| AK322582 |
| AKOS015836369 |
| AKOS015894970 |
| Alapril |
| Amicor |
| AN-36890 |
| anhydrous lisinopril |
| BB_NC-1454 |
| BCP9000856 |
| BDBM50367879 |
| BDBM66979 |
| BIDD:GT0755 |
| BPBio1_000290 |
| BRD-K67966701-335-03-5 |
| BRN 4276619 |
| BSPBio_000262 |
| C21H31N3O5 |
| Carace |
| CCG-39190 |
| CCRIS 3568 |
| CHEBI:43755 |
| CHEMBL1237 |
| cid_22887897 |
| Cipral |
| Coric |
| CPD000544473 |
| CS-2443 |
| CTK5F1429 |
| D07HGR |
| D08131 |
| DB00722 |
| Diroton |
| DivK1c_001037 |
| DL-434 |
| Doneka |
| DTXSID6040537 |
| EINECS 278-488-1 |
| FT-0627878 |
| GTPL6360 |
| Hipril |
| Hipril (TN) |
| HMS1921B14 |
| HMS2090O14 |
| HMS2092L21 |
| HMS2850N20 |
| HMS503O15 |
| HSDB 6852 |
| HY-18206 |
| I06-1895 |
| ICI-209K |
| IDI1_001037 |
| Inhibril |
| Inopril |
| Irumed |
| KBio1_001037 |
| KBio2_000977 |
| KBio2_003545 |
| KBio2_006113 |
| KBio3_002002 |
| KBioGR_001599 |
| KBioSS_000977 |
| KM1776 |
| KS-00000GHQ |
| KSC651I2T |
| L-Proline, 1-(N(sup 2)-(1-carboxy-3-phenylpropyl)-L-lysyl)-, (S)- |
| L-Proline, 1-(N2-(1-carboxy-3-phenylpropyl)-L-lysyl)- |
| L-Proline, 1-(N2-(1-carboxy-3-phenylpropyl)-L-lysyl)-, (S)- |
| L-Proline, N2-((1S)-1-carboxy-3-phenylpropyl)-L-lysyl- |
| L0220 |
| Laaven |
| Linopril |
| Linvas |
| Lipril |
| Lisinal |
| Lisinopril (anhydrous) |
| Lisinopril (INN) |
| Lisinopril (Zestril) |
| Lisinopril [INN] |
| Lisinopril anhydrous |
| Lisinopril hydrate |
| Lisinoprilum |
| Lisinoprilum [Latin] |
| Lisipril |
| Lisitec |
| Lisopril |
| Lisoril |
| Lispril |
| Listril |
| Lizinopril |
| Lizonoton |
| Longes |
| Loril |
| LPR |
| LS-118899 |
| Lysinopril |
| lysinopryl |
| MCULE-7813362088 |
| MFCD01698825 |
| MK 521 |
| MK 522 |
| MK-521 |
| MLS001306436 |
| MLS001306481 |
| MLS002154258 |
| MolPort-002-507-428 |
| N-(1(S)-Carboxy-3-phenylpropyl)-L-lysyl-L-proline |
| N-[N2 -(1(S)-carboxy-3-phenylpropyl)-L-lysyl]-L-proline |
| N-[N2 (1(S)-carboxy-3-phenylpropyl)-L-lysyl]-L-proline |
| N(2)-[(1S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-proline |
| N2-((S)-1-Carboxy-3-phenylpropyl)-L-lysyl-L-proline |
| N2-[(1S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-proline |
| Nanopril |
| NCGC00179623-01 |
| NINDS_001037 |
| Noperten |
| Novatec |
| NSC-751176 |
| NSC-758151 |
| NSC751176 |
| NSC758151 |
| Optimon |
| Pharmakon1600-01501217 |
| Presiten |
| Prestwick0_000301 |
| Prestwick1_000301 |
| Prestwick2_000301 |
| Prestwick3_000301 |
| Prinil |
| Prinivil |
| Prinivil (TN) |
| Prinvil |
| Qbrelis |
| RLAWWYSOJDYHDC-BZSNNMDCSA-N |
| s2076 |
| SAM002589993 |
| SBI-0051692.P002 |
| SC-18165 |
| SCHEMBL15680 |
| Sinopril |
| Sinopryl |
| Skopryl |
| SMR000544473 |
| SMR001233519 |
| SPBio_001351 |
| SPBio_002481 |
| Spectrum_000497 |
| SPECTRUM1501217 |
| Spectrum2_001456 |
| Spectrum3_000941 |
| Spectrum4_001040 |
| Spectrum5_000995 |
| SR-05000001786 |
| SR-05000001786-1 |
| Tensopril |
| Tensopril (TN) |
| Tensyn |
| Tersif |
| TL8005499 |
| UNII-7Q3P4BS2FD |
| Vitopril |
| Vivatec |
| Z2786051707 |
| Zestril |
| Zestril (TN) |
| ZINC3812863 |
US Patents and Regulatory Information for lisinopril
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Exclusivity Expiration |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sandoz | LISINOPRIL | lisinopril | TABLET;ORAL | 075999-004 | Jul 1, 2002 | DISCN | No | No | ➤ Sign Up | ➤ Sign Up | ➤ Sign Up | ||||
| Casi Pharms Inc | LISINOPRIL | lisinopril | TABLET;ORAL | 075994-002 | Jul 1, 2002 | AB | RX | No | No | ➤ Sign Up | ➤ Sign Up | ➤ Sign Up | |||
| Lupin | LISINOPRIL | lisinopril | TABLET;ORAL | 077321-006 | Sep 9, 2005 | AB | RX | No | No | ➤ Sign Up | ➤ Sign Up | ➤ Sign Up | |||
| Watson Labs | LISINOPRIL | lisinopril | TABLET;ORAL | 076059-002 | Jul 1, 2002 | AB | RX | No | No | ➤ Sign Up | ➤ Sign Up | ➤ Sign Up | |||
| Sandoz | LISINOPRIL | lisinopril | TABLET;ORAL | 075999-006 | Jul 1, 2002 | DISCN | No | No | ➤ Sign Up | ➤ Sign Up | ➤ Sign Up | ||||
| Ivax Sub Teva Pharms | LISINOPRIL | lisinopril | TABLET;ORAL | 075752-002 | Jul 1, 2002 | AB | RX | No | No | ➤ Sign Up | ➤ Sign Up | ➤ Sign Up | |||
| Merck | PRINIVIL | lisinopril | TABLET;ORAL | 019558-003 | Dec 29, 1987 | AB | RX | No | No | ➤ Sign Up | ➤ Sign Up | ➤ Sign Up | |||
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Exclusivity Expiration |
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Expired US Patents for lisinopril
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | Patent No. | Patent Expiration |
|---|---|---|---|---|---|---|---|
| Alvogen Malta | ZESTRIL | lisinopril | TABLET;ORAL | 019777-005 | Apr 29, 1993 | ➤ Sign Up | ➤ Sign Up |
| Merck | PRINIVIL | lisinopril | TABLET;ORAL | 019558-006 | Jan 28, 1994 | ➤ Sign Up | ➤ Sign Up |
| Alvogen Malta | ZESTRIL | lisinopril | TABLET;ORAL | 019777-001 | May 19, 1988 | ➤ Sign Up | ➤ Sign Up |
| Alvogen Malta | ZESTRIL | lisinopril | TABLET;ORAL | 019777-004 | May 19, 1988 | ➤ Sign Up | ➤ Sign Up |
| Merck | PRINIVIL | lisinopril | TABLET;ORAL | 019558-002 | Dec 29, 1987 | ➤ Sign Up | ➤ Sign Up |
| Alvogen Malta | ZESTRIL | lisinopril | TABLET;ORAL | 019777-003 | May 19, 1988 | ➤ Sign Up | ➤ Sign Up |
| Alvogen Malta | ZESTRIL | lisinopril | TABLET;ORAL | 019777-002 | May 19, 1988 | ➤ Sign Up | ➤ Sign Up |
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | Patent No. | Patent Expiration |
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International Patents for lisinopril
| Country | Document Number | Estimated Expiration |
|---|---|---|
| World Intellectual Property Organization (WIPO) | 2017075368 | ➤ Sign Up |
| Country | Document Number | Estimated Expiration |
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