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Generated: May 24, 2019

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QBRELIS Drug Profile

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Which patents cover Qbrelis, and what generic alternatives are available?

Qbrelis is a drug marketed by Silvergate Pharms and is included in one NDA. There are four patents protecting this drug.

This drug has six patent family members in six countries.

The generic ingredient in QBRELIS is lisinopril. There are twenty-one drug master file entries for this compound. Seventy-eight suppliers are listed for this compound. Additional details are available on the lisinopril profile page.

Drug patent expirations by year for QBRELIS
Pharmacology for QBRELIS
Medical Subject Heading (MeSH) Categories for QBRELIS
Synonyms for QBRELIS
(2S)-1-[(2S)-6-amino-2-[[(1S)-1-carboxy-3-phenyl-propyl]amino]hexanoyl]proline;hydrate
(2S)-1-[(2S)-6-amino-2-[[(1S)-1-carboxy-3-phenyl-propyl]amino]hexanoyl]pyrrolidine-2-carboxylic acid
(2S)-1-[(2S)-6-amino-2-[[(1S)-1-carboxy-3-phenyl-propyl]amino]hexanoyl]pyrrolidine-2-carboxylic acid dihydrate
(2S)-1-[(2S)-6-amino-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]-1-oxohexyl]-2-pyrrolidinecarboxylic acid
(2S)-1-[(2S)-6-amino-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]-1-oxohexyl]-2-pyrrolidinecarboxylic acid;hydrate
(2S)-1-[(2S)-6-amino-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]hexanoyl]pyrrolidine-2-carboxylic acid;dihydrate
(2S)-1-[(2S)-6-amino-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]hexanoyl]pyrrolidine-2-carboxylic acid;hydrate
(2S)-1-[(2S)-6-amino-2-[[(2S)-1-hydroxy-1-oxo-4-phenylbutan-2-yl]amino]hexanoyl]pyrrolidine-2-carboxylic acid
(2S)-1-[(2S)-6-amino-2-[[(2S)-1-hydroxy-1-oxo-4-phenylbutan-2-yl]amino]hexanoyl]pyrrolidine-2-carboxylic acid dihydrate
(2S)-1-[(2S)-6-amino-2-{[(1S)-1-carboxy-3-phenylpropyl]amino}hexanoyl]pyrrolidine-2-carboxylic acid
(2S)-1-[(2S)-6-azanyl-2-[[(2S)-1-oxidanyl-1-oxidanylidene-4-phenyl-butan-2-yl]amino]hexanoyl]pyrrolidine-2-carboxylic acid
(2S)-1-[(2S)-6-azanyl-2-[[(2S)-1-oxidanyl-1-oxidanylidene-4-phenyl-butan-2-yl]amino]hexanoyl]pyrrolidine-2-carboxylic acid;hydrate
(S)-1-((S)-6-Amino-2-(((S)-1-carboxy-3-phenylpropyl)amino)hexanoyl)pyrrolidine-2-carboxylic acid
(S)-1-((S)-6-amino-2-((S)-1-carboxy-3-phenylpropylamino)hexanoyl)pyrrolidine-2-carboxylic acid
(S)-1-(N(2)-(1-carboxy-3-phenylpropyl)-L-lysyl)-L-proline
(S)-1-(N(2)-(1-carboxy-3-phenylpropyl)-L-lysyl)-L-proline dihydrate
(S)-1-(N(sup 2)-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline
(S)-1-(N(sup 2)-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline dihydrate
(S)-1-(N2-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline
(S)-1-(N2-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline dihydrate
(S)-1-[N2-(1-carboxy-3-phenylpropyl)-L-lysyl]-L-proline
(S)-1-[N2-(1-Carboxy-3-phenylpropyl)-lysyl-proline dihydrate
(S)-Lisinopril
[N2-[(S)-1-CARBOXY-3-PHENYLPROPYL]-L-LYSYL-L-PROLINE
1-(N(sup 2)-((S)-1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline dihydrate
1-(N2-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline
1-[Nalpha-[(S)-1-Carboxy-3-phenylpropyl]-L-lysyl]-L-proline
1835AH
2517AH
54256-EP2270011A1
54256-EP2272834A1
54256-EP2277879A1
54256-EP2287165A2
54256-EP2287166A2
54256-EP2292228A1
54256-EP2292620A2
54256-EP2298742A1
54256-EP2298776A1
54256-EP2298779A1
54256-EP2301923A1
54256-EP2301929A1
54256-EP2301931A1
54256-EP2301935A1
54256-EP2305648A1
54256-EP2305674A1
54256-EP2308562A2
547L983
76547-98-3
76547-98-3 (parent cpd)
77726-95-5
7Q3P4BS2FD
82009-35-6 (sulfate (1:2))
83915-83-7
83915-83-7 (Parent)
915L837
A838743
AB00052250_14
AB00052250_15
AB00052250-13
AB04852
AB1004847
AC-6226
AC1NSFPC
AC1NSFPF
Acerbon
Acercomp
AK322582
AKOS015836369
AKOS015894970
AKOS015950799
Alapril
Amicor
AN-36890
AN-6585
API0005525
AX8136408
BCP9000856
BDBM50367879
BDBM66979
BIDD:GT0755
BPBio1_000290
BRD-K67966701-335-03-5
BRN 4276619
BSPBio_000262
C21H31N3O5
C21H31N3O5.2H2O
Carace
CAS-83915-83-7
CCG-220301
CCG-39190
CCRIS 3568
CHEBI:43755
CHEBI:6503
CHEMBL1237
CHEMBL419213
cid_22887897
Cipral
Cipril
Coric
CPD000544473
CS-2443
CS-2444
CTK5F1429
D00362
D08131
DB00722
Diroton
DivK1c_001037
DL-434
Doneka
DSSTox_CID_25600
DSSTox_GSID_45600
DSSTox_RID_80993
DTXSID2045600
DTXSID6040537
E7199S1YWR
EINECS 278-488-1
FT-0627878
GTPL6360
H528
Hipril
HMS1568N04
HMS1921B14
HMS2090O14
HMS2092L21
HMS2095N04
HMS2850N20
HMS3712N04
HMS503O15
HSDB 6852
HY-18206
HY-18206A
I06-1895
ICI-209K
IDI1_001037
Inhibril
Inopril
Irumed
KBio1_001037
KBio2_000977
KBio2_003545
KBio2_006113
KBio3_002002
KBioGR_001599
KBioSS_000977
KM1776
KS-00000GHQ
KS-1078
KSC651I2T
L-Proline, 1-(N(sup 2)-(1-carboxy-3-phenylpropyl)-L-lysyl)-, (S)-
L-Proline, 1-(N(sup 2)-(1-carboxy-3-phenylpropyl)-L-lysyl)-, dihydrate, (S)-
L-Proline, 1-(N2-(1-carboxy-3-phenylpropyl)-L-lysyl)-
L-Proline, 1-(N2-(1-carboxy-3-phenylpropyl)-L-lysyl)-, (S)-
L-Proline, 1-(N2-(1-carboxy-3-phenylpropyl)-L-lysyl)-, dihydrate, (S)-
L-Proline, N2-((1S)-1-carboxy-3-phenylpropyl)-L-lysyl-
L-Proline, N2-[(1S)-1-carboxy-3-phenylpropyl]-L-lysyl-, dihydrate
L-Proline,1-(N2(1-carboxy-3-phenylpropyl)-L-lysyl)-dihydrate,(S)
L0220
Laaven
Linopril
Linvas
Lipril
Lisinal
lisinopril
Lisinopril (anhydrous)
Lisinopril (dihydrate)
Lisinopril (INN)
Lisinopril (USP)
Lisinopril (Zestril)
Lisinopril [INN]
Lisinopril [USAN:INN:BAN:JAN]
Lisinopril [USAN:USP:INN:BAN:JAN]
Lisinopril anhydrous
Lisinopril dihydrate
Lisinopril dihydrate, British Pharmacopoeia (BP) Reference Standard
Lisinopril dihydrate, European Pharmacopoeia (EP) Reference Standard
Lisinopril for peak identification, European Pharmacopoeia (EP) Reference Standard
Lisinopril for system suitability A, European Pharmacopoeia (EP) Reference Standard
Lisinopril hydrate (JP17)
lisinopril-dihydrat
Lisinopril, >=98% (HPLC)
Lisinopril, Pharmaceutical Secondary Standard; Certified Reference Material
Lisinopril, United States Pharmacopeia (USP) Reference Standard
Lisinoprilum
Lisinoprilum [Latin]
Lisipril
Lisitec
Lisopril
Lisoril
Lispril
Listril
Lizinopril
Lizonoton
Longes
Loril
LPR
LS-118899
LS-118900
Lysinopril
lysinopryl
MCULE-7813362088
MFCD01698825
MK 521
MK 522
MK-521
MLS001306436
MLS001306481
MLS002154258
MolPort-002-507-428
MolPort-005-933-636
N-(1(S)-Carboxy-3-phenylpropyl)-L-lysyl-L-proline
N-[N2 -(1(S)-carboxy-3-phenylpropyl)-L-lysyl]-L-proline
N-[N2 (1(S)-carboxy-3-phenylpropyl)-L-lysyl]-L-proline
N(2)-[(1S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-proline
N(2)-[(1S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-proline dihydrate
N2-((S)-1-Carboxy-3-phenylpropyl)-L-lysyl-L-proline
N2-[(1S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-proline
Nanopril
NCGC00017141-01
NCGC00179623-01
NCGC00179623-04
NINDS_001037
Noperten
Novatec
NSC-751176
NSC-758151
NSC751176
NSC758151
Optimon
Pharmakon1600-01501217
Presiten
Prestwick_613
Prestwick0_000301
Prestwick1_000301
Prestwick2_000301
Prestwick3_000301
Prinil
Prinivil
Prinivil (TN)
Prinvil
Ranolip
Renacor
RLAWWYSOJDYHDC-BZSNNMDCSA-N
s2076
SAM002589993
SBI-0051692.P002
SC-18165
SC-25401
SCHEMBL15680
SCHEMBL542591
Sinopril
Sinopryl
Skopryl
SMR000544473
SMR001233519
SPBio_001351
SPBio_002481
Spectrum_000497
SPECTRUM1501217
Spectrum2_001456
Spectrum3_000941
Spectrum4_001040
Spectrum5_000995
SR-01000801314
SR-01000801314-3
SR-05000001786
SR-05000001786-1
ST24047491
Tensopril
Tensyn
Tersif
TL8005499
Tox21_110798
Tox21_110798_1
UNII-7Q3P4BS2FD
UNII-E7199S1YWR
Vitopril
Vivatec
Z2786051707
Zestril
Zestril (TN)
ZINC3812863

US Patents and Regulatory Information for QBRELIS

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Silvergate Pharms QBRELIS lisinopril SOLUTION;ORAL 208401-001 Jul 29, 2016 RX Yes Yes ➤ Sign Up ➤ Sign Up ➤ Sign Up
Silvergate Pharms QBRELIS lisinopril SOLUTION;ORAL 208401-001 Jul 29, 2016 RX Yes Yes ➤ Sign Up ➤ Sign Up ➤ Sign Up
Silvergate Pharms QBRELIS lisinopril SOLUTION;ORAL 208401-001 Jul 29, 2016 RX Yes Yes ➤ Sign Up ➤ Sign Up Y ➤ Sign Up
Silvergate Pharms QBRELIS lisinopril SOLUTION;ORAL 208401-001 Jul 29, 2016 RX Yes Yes ➤ Sign Up ➤ Sign Up Y ➤ Sign Up
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration

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