You are 3 steps away
from making better decisions

Serving leading biopharmaceutical companies globally:

Express Scripts
Johnson and Johnson
McKesson
Harvard Business School
McKinsey
Colorcon

Last Updated: May 30, 2020

DrugPatentWatch Database Preview

CALCIPOTRIENE - Generic Drug Details

» See Plans and Pricing

« Back to Dashboard

What are the generic drug sources for calcipotriene and what is the scope of freedom to operate?

Calcipotriene is the generic ingredient in three branded drugs marketed by Mayne Pharma, Glenmark Pharms, Tolmar, Leo Pharma As, Glenmark Pharms Inc, Acp Nimble, Fougera Pharms, Hi Tech Pharma, Novel Labs Inc, and Leo Pharm, and is included in twelve NDAs. There are two patents protecting this compound and one Paragraph IV challenge. Additional information is available in the individual branded drug profile pages.

Calcipotriene has twenty-eight patent family members in thirteen countries.

There are twelve drug master file entries for calcipotriene. Fourteen suppliers are listed for this compound.

Drug Prices for CALCIPOTRIENE

See drug prices for CALCIPOTRIENE

Recent Clinical Trials for CALCIPOTRIENE

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
University of Alabama at BirminghamPhase 4
Eli Lilly and CompanyPhase 4
Tulane UniversityEarly Phase 1

See all CALCIPOTRIENE clinical trials

Recent Litigation for CALCIPOTRIENE

Identify potential future generic entrants

District Court Litigation
Case NameDate
LEO Pharma A/S v. Tolmar Inc.2010-08-25
LEO Pharma A/S v. Tolmar Inc.2010-04-06
Bone Care International LLC v. Pentech Pharmaceuticals, Inc.2008-02-21

See all CALCIPOTRIENE litigation

Pharmacology for CALCIPOTRIENE
Synonyms for CALCIPOTRIENE
(1?,3?,5Z,7E,22E,24S)-24-Cyclopropyl-9,10-secochola-5,7,10(19),22-tetraene-1,3,24-triol
(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(E,2R,5S)-5-cyclopropyl-5-hydroxypent-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol
(1S,3R,5Z,7E,14beta,17alpha,22E,24S)-26,27-cyclo-9,10-secocholesta-5,7,10,22-tetraene-1,3,24-triol
(1S,3R,5Z,7E,22E,24S)-26,27-cyclo-9,10-secocholesta-5,7,10,22-tetraene-1,3,24-triol hydrate
(1S,5Z,7Z,17ALPHA,22E)-24-CYCLOPROPYL-9,10-SECOCHOLA-5,7,10,22-TETRAENE-1,3,24-TRIOL; 1-ALPHA,24S-(OH)2-22-ENE-26,27-DEHYDROVITAMIN D3
(22E)-(24S)-1alpha,24-dihydroxy-26,27-cyclo-22,23-didehydrovitamin D3 / (22E)-(24S)-1alpha,24-dihydroxy-26,27-cyclo-22,23-didehydrocholecalciferol / Calcipotriol
(5Z,7E,22E,24S)-24-Cyclopropyl-9,10-secochola-5,7,10(19),22-tetraene-1alpha,3beta,24-triol
(5Z,7E,22E,24S)-24-Cyclopropyl-9,10-secochola-5,7,10(19),22-tetraene-1alpha,3beta,24-triol hydrate
(5Z,7E,22E)-(1S,3R,24S)-26,27-cyclo-9,10-seco-5,7,10(19),22-cholestatetraene-1,3,24-triol
(5Z,7E,24S)-26,27-Cyclo-9,10-secocholesta-5,7,10(19),22-tetraene-1alpha,3beta,24-triol
112828-00-9
112965-21-6
143NQ3779B
147657-22-5
1652AH
1s19
24207-EP2275420A1
24207-EP2295055A2
24207-EP2295416A2
24207-EP2298748A2
24207-EP2298764A1
24207-EP2298765A1
24207-EP2305640A2
24207-EP2305642A2
24207-EP2308861A1
24207-EP2311453A1
24207-EP2314590A1
828C009
9,10-Secochola-5,7,10(19),22-tetraene-1,3,24-triol, 24-cyclopropyl-, (1alpha,3beta,5Z,7E,22E,24S)-
AB00698343-05
AKOS015855239
AKOS025312514
AS-56390
BDBM50369964
BMS-181161
C27H40O3.H2O
Calcipotriene (USAN)
Calcipotriene [USAN]
CALCIPOTRIENE HYDRATE
Calcipotriene monohydrate
Calcipotriol
Calcipotriol (JAN)
Calcipotriol (monohydrate)
Calcipotriol [INN]
Calcipotriol hydrate
Calcipotriol hydrate (JAN)
Calcipotriol hydrate, >=98% (HPLC)
Calcipotriol monohydrate
Calciptriol
Calcitrene
CAS-112965-21-6
CCG-100949
CCRIS 7700
CHEBI:50749
CHEBI:90861
CHEMBL1200666
CPD000466353
CS-0387
CS-0812
D01125
D10198
Daivonex
DB02300
Divonex
Dovonex
Dovonex (TN)
DSSTox_CID_26648
DSSTox_GSID_46648
DSSTox_RID_81793
DTXSID0046648
Epitope ID:114242
GTPL2778
HMS2051N11
HMS2089J08
HMS3269P03
HMS3413D04
HMS3677D04
HMS3713K08
HY-10001
HY-10001A
LMST03020106
LWQQLNNNIPYSNX-UROSTWAQSA-N
MC 903
MC-903
MC903
MFCD10567086
MLS000759467
MLS001424130
NC00199
NCGC00167465-01
NCGC00167465-02
O763
PRI 2201
PRI-2201
Psorcutan
PubChem18810
PubChem19334
Q155683
Q27162836
s3739
S7499TYY6G
SCHEMBL2853
SCHEMBL465450
SMR000466353
Sorilux
SR-01000762910
SR-01000762910-3
SR-01000762910-4
STF-115469
Tox21_112469
Tox21_112469_1
U-0267
UNII-143NQ3779B
UNII-S7499TYY6G
W-5148
W-5449
ZINC3921872
Paragraph IV (Patent) Challenges for CALCIPOTRIENE
Tradename Dosage Ingredient NDA Submissiondate
DOVONEX CREAM;TOPICAL calcipotriene 020554 2009-12-02
DOVONEX SOLUTION;TOPICAL calcipotriene 020611 2006-05-19

US Patents and Regulatory Information for CALCIPOTRIENE

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Glenmark Pharms Inc CALCIPOTRIENE calcipotriene OINTMENT;TOPICAL 090633-001 Mar 24, 2010 RX No Yes   Start Trial   Start Trial   Start Trial
Leo Pharm DOVONEX calcipotriene SOLUTION;TOPICAL 020611-001 Mar 3, 1997 DISCN Yes No   Start Trial   Start Trial   Start Trial
Mayne Pharma SORILUX calcipotriene AEROSOL, FOAM;TOPICAL 022563-001 Oct 6, 2010 RX Yes Yes   Start Trial   Start Trial Y   Start Trial
Fougera Pharms CALCIPOTRIENE calcipotriene SOLUTION;TOPICAL 078305-001 May 6, 2008 AT RX No No   Start Trial   Start Trial   Start Trial
Glenmark Pharms CALCIPOTRIENE calcipotriene CREAM;TOPICAL 205772-001 Jun 9, 2015 AB RX No No   Start Trial   Start Trial   Start Trial
Novel Labs Inc CALCIPOTRIENE calcipotriene SOLUTION;TOPICAL 207163-001 Dec 26, 2017 AT RX No No   Start Trial   Start Trial   Start Trial
Acp Nimble CALCIPOTRIENE calcipotriene SOLUTION;TOPICAL 078468-001 Mar 24, 2011 AT RX No No   Start Trial   Start Trial   Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

Expired US Patents for CALCIPOTRIENE

Applicant Tradename Generic Name Dosage NDA Approval Date Patent No. Patent Expiration
Leo Pharma As DOVONEX calcipotriene CREAM;TOPICAL 020554-001 Jul 22, 1996   Start Trial   Start Trial
Leo Pharma As DOVONEX calcipotriene CREAM;TOPICAL 020554-001 Jul 22, 1996   Start Trial   Start Trial
Leo Pharm DOVONEX calcipotriene SOLUTION;TOPICAL 020611-001 Mar 3, 1997   Start Trial   Start Trial
Leo Pharm DOVONEX calcipotriene SOLUTION;TOPICAL 020611-001 Mar 3, 1997   Start Trial   Start Trial
Leo Pharma As DOVONEX calcipotriene OINTMENT;TOPICAL 020273-001 Dec 29, 1993   Start Trial   Start Trial
Leo Pharma As DOVONEX calcipotriene CREAM;TOPICAL 020554-001 Jul 22, 1996   Start Trial   Start Trial
Leo Pharm DOVONEX calcipotriene SOLUTION;TOPICAL 020611-001 Mar 3, 1997   Start Trial   Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >Patent No. >Patent Expiration

Make Better Decisions: Try a trial or see plans & pricing

Serving leading biopharmaceutical companies globally:

Express Scripts
Johnson and Johnson
McKesson
Harvard Business School
McKinsey
Colorcon

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.