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Last Updated: April 3, 2026

METRONIDAZOLE IN PLASTIC CONTAINER Drug Patent Profile


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When do Metronidazole In Plastic Container patents expire, and what generic alternatives are available?

Metronidazole In Plastic Container is a drug marketed by Amneal, Baxter Hlthcare Corp, Gland, Hospira, Inforlife, and Rising. and is included in six NDAs.

The generic ingredient in METRONIDAZOLE IN PLASTIC CONTAINER is metronidazole. There are eighteen drug master file entries for this compound. Sixty-seven suppliers are listed for this compound. Additional details are available on the metronidazole profile page.

DrugPatentWatch® Litigation and Generic Entry Outlook for Metronidazole In Plastic Container

A generic version of METRONIDAZOLE IN PLASTIC CONTAINER was approved as metronidazole by TEVA PHARMS USA on November 6th, 1984.

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  • What is the 5 year forecast for METRONIDAZOLE IN PLASTIC CONTAINER?
  • What are the global sales for METRONIDAZOLE IN PLASTIC CONTAINER?
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Summary for METRONIDAZOLE IN PLASTIC CONTAINER
Drug patent expirations by year for METRONIDAZOLE IN PLASTIC CONTAINER
Recent Clinical Trials for METRONIDAZOLE IN PLASTIC CONTAINER

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SponsorPhase
Universitt LuzernPHASE4
Faiz ur rahmanNA
Stanford UniversityEARLY_PHASE1

See all METRONIDAZOLE IN PLASTIC CONTAINER clinical trials

Pharmacology for METRONIDAZOLE IN PLASTIC CONTAINER

US Patents and Regulatory Information for METRONIDAZOLE IN PLASTIC CONTAINER

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Amneal METRONIDAZOLE IN PLASTIC CONTAINER metronidazole INJECTABLE;INJECTION 217665-001 May 24, 2023 AP RX No No ⤷  Start Trial ⤷  Start Trial ⤷  Start Trial
Hospira METRONIDAZOLE IN PLASTIC CONTAINER metronidazole INJECTABLE;INJECTION 018890-002 Nov 18, 1983 AP RX Yes Yes ⤷  Start Trial ⤷  Start Trial ⤷  Start Trial
Baxter Hlthcare Corp METRONIDAZOLE IN PLASTIC CONTAINER metronidazole INJECTABLE;INJECTION 078084-001 Mar 31, 2008 DISCN No No ⤷  Start Trial ⤷  Start Trial ⤷  Start Trial
Gland METRONIDAZOLE IN PLASTIC CONTAINER metronidazole INJECTABLE;INJECTION 212435-001 Aug 3, 2020 AP RX No No ⤷  Start Trial ⤷  Start Trial ⤷  Start Trial
Rising METRONIDAZOLE IN PLASTIC CONTAINER metronidazole INJECTABLE;INJECTION 205531-001 May 9, 2017 DISCN No No ⤷  Start Trial ⤷  Start Trial ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

METRONIDAZOLE IN PLASTIC CONTAINER Market Analysis and Financial Projection

Last updated: February 9, 2026

What Are the Market Dynamics for Metronidazole in Plastic Containers?

The global market for metronidazole, particularly in plastic containers, reflects increased demand driven by multiple factors. It is primarily used as an antimicrobial agent for bacterial and protozoal infections, with applications in gastrointestinal, gynecological, and dermatological treatments.

Market Drivers

  • Rising Infectious Diseases: Increased prevalence of bacterial and protozoal infections sustains demand for metronidazole. World Health Organization (WHO) reports show a surge in parasitic infections globally, especially in developing countries.
  • Convenience and Safety of Plastic Containers: Plastic packaging offers advantages such as shatter resistance, lighter weight, and lower costs compared to glass. This drives pharmaceutical companies to select plastics for drug packaging. Regulatory agencies, including the FDA, endorse plastic containers as safe for oral medications provided they meet quality standards.
  • Expansion in Developing Markets: Countries in Asia, Africa, and Latin America experience rising healthcare infrastructure investments, boosting distribution channels for oral antibiotics like metronidazole.

Market Challenges

  • Generic Competition: The widespread availability of generic versions compresses profit margins and accelerates price erosions.
  • Regulatory Changes: Strict regulations concerning plastic container materials and their compatibility with pharmaceutical compounds influence packaging choices.
  • Environmental Regulations: Increasing focus on plastic waste management may impact packaging strategies, potentially raising costs or prompting alternative packaging approaches.

Market Size and Growth Rate

  • The global metronidazole market was valued at approximately USD 390 million in 2021. It is projected to grow at a compound annual growth rate (CAGR) of about 3.2% from 2022 to 2028.
  • Regionally, Asia-Pacific leads in growth owing to high disease burden and expanding healthcare access. North America and Europe hold mature markets but face competition from alternative therapies.

Competitive Landscape

Major players include Pfizer, Teva Pharmaceuticals, and Mylan, which supply metronidazole in plastic bottles, blister packs, and other forms. These companies focus on maintaining regulatory compliance and optimizing packaging solutions for distribution efficiency.


What Is the Financial Trajectory for Metronidazole in Plastic Containers?

Revenue Trends

  • The revenue from metronidazole sales in plastic containers has shown consistent growth aligned with the market size increase. In 2021, the estimated global revenue was USD 380-400 million.
  • Pricing pressure from generics has kept average selling prices (ASP) low. The ASP for a standard 250 mg tablet averages around USD 0.03–0.05 per unit, depending on the region and manufacturer.

Cost Structures

  • The manufacturing cost per unit includes active pharmaceutical ingredient (API) costs, packaging, labor, and distribution. API costs constitute approximately 40% of total production costs.
  • Packaging costs, caused by the choice of plastic (typically high-density polyethylene or polypropylene), account for 10–15%. Innovation in packaging materials, such as biodegradable plastics, aims to reduce long-term costs.

Profit Margins

  • Margins vary widely; branded products can achieve gross margins of 30–50%. In contrast, generics often operate on margins as low as 10–20% due to high competition.
  • Cost reduction initiatives focus on manufacturing efficiencies and supply chain optimizations. Outsourcing manufacturing to countries with lower labor costs has become common.

Future Revenue Projections

  • With a steady CAGR of roughly 3%, revenue could reach USD 470–490 million by 2028, assuming market stability.
  • Market concentration is expected to decrease as new entrants and regional manufacturers expand, potentially causing further price competition.

Regulatory and Environmental Risks Impacting Financials

  • Changes in regulations concerning plastic container materials could result in increased compliance costs.
  • Moves toward reducing plastic waste could lead manufacturers to adopt alternative packaging, possibly incurring capital expenditures but offering long-term savings or regulatory advantages.

Key Takeaways

  • The metronidazole market is driven by demand for effective antimicrobial treatments amid rising infectious disease burdens.
  • Plastic containers dominate packaging due to their safety, cost-effectiveness, and convenience, aligning with logistics and regulatory trends.
  • The market is mature in developed regions, with growth primarily fueled by emerging markets’ expansion.
  • Revenue remains under pressure from generic competition, with margins low but stable amid steady demand.
  • Environmental policies and regulations on plastics could reshape packaging strategies, impacting costs and product availability.

FAQs

  1. What factors influence the choice of plastic container for metronidazole?
    Compatibility with the drug, regulatory safety standards, cost, shatter resistance, and logistical considerations primarily determine packaging choice.

  2. How does regulatory oversight impact the manufacturing and packaging of metronidazole?
    Agencies enforce standards on plastic materials and drug stability, which can increase costs or necessitate material changes.

  3. Are there environmental concerns associated with plastic containers for pharmaceuticals?
    Yes. Growing emphasis on plastic waste reduction leads to potential bans or restrictions, influencing future packaging decisions.

  4. What are the main regions contributing to the growth of the metronidazole market?
    Asia-Pacific, Latin America, and parts of Africa see significant growth, driven by disease prevalence and healthcare infrastructure development.

  5. How is technological innovation influencing packaging and cost structures?
    Adoption of biodegradable plastics and advanced manufacturing techniques can lower long-term costs and meet regulatory requirements.


References

[1] MarketWatch. (2022). Metronidazole Market Size, Share & Trends.
[2] WHO. (2021). Global Infectious Disease Estimates.
[3] Transparency Market Research. (2022). Antibiotics Market – Industry Analysis.
[4] U.S. Food and Drug Administration. (2021). Guidance on Packaging Materials for Pharmaceuticals.

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