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CORLANOR Drug Profile

Which patents cover Corlanor, and what generic alternatives are available?

Corlanor is a drug marketed by Amgen Inc and is included in one NDA. There are four patents protecting this drug.

This drug has ninety-six patent family members in forty-two countries.

The generic ingredient in CORLANOR is ivabradine hydrochloride. There are five drug master file entries for this compound. One supplier is listed for this compound. Additional details are available on the ivabradine hydrochloride profile page.

Summary for CORLANOR

International Patents:	96
US Patents:	4
Applicants:	1
NDAs:	1
Suppliers / Packagers:	1
Bulk Api Vendors:	103
Clinical Trials:	5
Patent Applications:	293
Drug Prices:	Drug price information for CORLANOR
DailyMed Link:	CORLANOR at DailyMed

Drug patent expirations by year for CORLANOR

Generic Entry Opportunity Date for CORLANOR

Generic Entry Date for CORLANOR^: ➤ Sign Up* Constraining patent/regulatory exclusivity: ➤ Sign Up NDA: 206143 Dosage: TABLET;ORAL

^*The generic entry opportunity date is the latter of the last compound-claiming patent and the last regulatory exclusivity protection. Many factors can influence early or later generic entry. This date is provided as a rough estimate of generic entry potential and should not be used as an independent source.

Pharmacology for CORLANOR

Drug Class	Hyperpolarization-activated Cyclic Nucleotide-gated Channel Blocker
Mechanism of Action	Hyperpolarization-activated Cyclic Nucleotide-gated Channel Antagonists

Synonyms for CORLANOR

(S)-3-(3-(((3,4-Dimethoxybicyclo(4.2.0)octa-1,3,5-trien-7-yl)methyl)methylamino)propyl)-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one
148870-61-5
155974-00-8
185824-EP2276742A1
2H-3-Benzazepin-2-one, 3-(3-(((3,4-dimethoxybicyclo(4.2.0)octa-1,3,5-trien-7-yl)methyl)methylamino)propyl)-1,3,4,5-tetrahydro-7,8-dimethoxy-, (S)-
3-(3-((((7S)-3,4-Dimethoxybicyclo(4.2.0)octa-1,3,5-trien-7-yl)methyl)methylamino)propyl)-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one
3-[3-({[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}(methyl)amino)propyl]-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one
3-[3-[[(7S)-3,4-dimethoxy-7-bicyclo[4.2.0]octa-1,3,5-trienyl]methyl-methyl-amino]propyl]-7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-one
3-[3-[[(7S)-3,4-dimethoxy-7-bicyclo[4.2.0]octa-1,3,5-trienyl]methyl-methylamino]propyl]-7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-one
3-[3-[[(8S)-3,4-dimethoxy-8-bicyclo[4.2.0]octa-1,3,5-trienyl]methyl-methylamino]propyl]-7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-one
3-{3-[{[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}(methyl)-amino]propyl}-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one
3-{3-[{[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}(methyl)amino]-propyl}-7.8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one
3-{3-[{[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}(methyl)amino]propyl}-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one
3H48L0LPZQ
7-(3-((((R)-4,5-dimethoxy-1,2-dihydrocyclobutabenzen-1-yl)methyl)(methyl)amino)propyl)-2,3-dimethoxy-8,9-dihydro-5H-benzo[7]annulen-6(7H)-one
7,8-Dimethoxy-3-(3-(((4,5-dimethoxybenzocyclobutan-1-yl)methyl)methylamino)propyl)-1,3,4,5-tetrahydro-2H-benzazepin-2-one
AB01566878_01
AC-8848
AC1L31ZF
ACRHBAYQBXXRTO-OAQYLSRUSA-N
AJ-45658
AKOS015896494
AN-5299
API0006402
BDBM50326992
C27H36N2O5
CHEBI:85966
CHEMBL471737
coraxan
Corlentor
D07165
D0S9QA
DB09083
DTXSID2048240
FT-0697755
GTPL2357
HE069588
HE314684
Ivabradin
Ivabradina
Ivabradine
Ivabradine (USAN/INN)
Ivabradine [INN]
Ivabradine [USAN:INN:BAN]
Ivabradinum
LS-28023
MolPort-003-986-484
Procoralan
S 16257
S 16257-2
S-16257
S-16257-2
S-16260-2
SC-83347
SCHEMBL23472
TL8001175
UNII-3H48L0LPZQ
UNII-C8ADC441ME component ACRHBAYQBXXRTO-OAQYLSRUSA-N
V0092
ZINC3805768

US Patents and Regulatory Information for CORLANOR

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Glossary

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Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Exclusivity Expiration
Amgen Inc	CORLANOR	ivabradine hydrochloride	TABLET;ORAL	206143-001	Apr 15, 2015		RX	Yes	No	➤ Sign Up	➤ Sign Up	Y	Y		➤ Sign Up
Amgen Inc	CORLANOR	ivabradine hydrochloride	TABLET;ORAL	206143-002	Apr 15, 2015		RX	Yes	Yes	➤ Sign Up	➤ Sign Up	Y	Y		➤ Sign Up
Amgen Inc	CORLANOR	ivabradine hydrochloride	TABLET;ORAL	206143-001	Apr 15, 2015		RX	Yes	No	➤ Sign Up	➤ Sign Up	Y	Y		➤ Sign Up
Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Exclusivity Expiration

International Patents for CORLANOR

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Country	Document Number	Estimated Expiration
Germany	602006002624	➤ Sign Up
World Intellectual Property Organization (WIPO)	2006092493	➤ Sign Up
European Patent Office	1695965	➤ Sign Up
Country	Document Number	Estimated Expiration

Summary for CORLANOR

Generic Entry Opportunity Date for CORLANOR

Pharmacology for CORLANOR

Synonyms for CORLANOR

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