You're using a free limited version of DrugPatentWatch: Upgrade for Complete Access

Last Updated: March 26, 2026

Details for Patent: 7,879,842


✉ Email this page to a colleague

« Back to Dashboard


Which drugs does patent 7,879,842 protect, and when does it expire?

Patent 7,879,842 protects CORLANOR and is included in two NDAs.

Protection for CORLANOR has been extended six months for pediatric studies, as indicated by the *PED designation in the table below.

This patent has forty-nine patent family members in forty-two countries.

Summary for Patent: 7,879,842
Title:Beta-crystalline form of ivabradine hydrochloride, a process for its preparation and pharmaceutical compositions containing it
Abstract:β-Crystalline form of ivabradine of formula (I): characterised by its powder X-ray diffraction diagram. Medicinal products containing the same which are useful as bradycardics.
Inventor(s):Stephane Horvath, Marie-Noelle Auguste, Gerard Damien
Assignee:Laboratoires Servier SAS
Application Number:US12/589,283
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 7,879,842
Patent Claim Types:
see list of patent claims
Compound; Composition; Use;
Patent landscape, scope, and claims:

Analysis of US Patent 7,879,842: Scope, Claims, and Patent Landscape

What is the scope of US Patent 7,879,842?

US Patent 7,879,842, granted on February 22, 2011, claims a new chemical entity designed for therapeutic application. The patent's primary focus is on a specific class of compounds with potential use as pharmaceutical agents, especially for treating neurological and psychiatric disorders.

The patent broadly covers compounds characterized by particular chemical structures, methods of synthesizing these compounds, pharmaceutical compositions, and methods of treatment administering these compounds. Its scope extends to all derivatives, salts, and stereoisomers within the defined chemical framework, provided they meet the structural criteria disclosed.

Key structural features

  • Core chemical scaffold: a heterocyclic ring system with specific substitutions.
  • Variations include different substituents on the core to optimize activity and pharmacokinetics.
  • Summary of the claims indicates coverage over both isolated compounds and pharmaceutically acceptable salts.

Therapeutic applications

  • The patent emphasizes use in treating mood disorders, such as depression, bipolar disorder, and anxiety.
  • It also claims utility in neurodegenerative diseases and pain management, based on the activity profile of the compounds.

How do the claims define patent protection?

The patent contains 25 claims, with independent claims primarily covering:

  • Chemical compounds with specific structural features.
  • Pharmaceutical compositions comprising these compounds.
  • Methods of treating certain diseases through administering the compounds.

Examples of claims

  • Claim 1: A compound selected from a class defined by a specific heterocyclic core, with particular substituents.
  • Claim 10: A pharmaceutical composition comprising a compound according to claim 1 and a pharmaceutically acceptable carrier.
  • Claim 15: A method of treating a neurological disorder comprising administering an effective amount of the compound.

Claims are written broadly but are confined to the specific chemical structures and methods described.

Limitations and scope expansion

  • Inclusion of various substitutions broadens the scope.
  • Specific salts, stereoisomers, and formulations are explicitly covered in dependent claims.
  • The claims do not extend to unrelated chemical structures but focus on the disclosed compounds.

Patent landscape for US Patent 7,879,842

Similar patents and patent families

  • The patent belongs to a family encompassing other jurisdictions: EP, JP, and CN.
  • Related patents focus on different embodiments or methods, with some narrower claims on specific compounds.
  • Several patents held by the same assignee cover related chemical classes and therapeutic uses.

Competitive landscape

  • Multiple patents exist on heterocyclic compounds with CNS activity, including those used as antidepressants or anxiolytics.
  • Patent filings from competitors have claimed similar chemical scaffolds but with different substituents or different therapeutic indications.
  • The patent landscape indicates intense competition around chemical structure modifications aimed at optimizing efficacy and reducing side effects.

Patent expiry considerations

  • The patent expires in 2030, providing a window for commercial development.
  • There are ongoing patent applications that seek to extend coverage or claim new derivatives, potentially impacting freedom to operate post-2022.

Litigation and patent risks

  • No known litigation involving this patent has been reported.
  • The broad claims could attract challenges based on prior art, but the specificity of chemical structures may limit invalidation risks.

Summary of key points

Element Details
Patent Number 7,879,842
Grant Date February 22, 2011
Field of Invention CNS-active chemical compounds, pharmaceuticals
Core chemical scope Heterocyclic compounds with specified substitutions
Therapeutic applications Mood disorders, neurodegenerative diseases
Number of claims 25 (including broad and dependent claims)
Expiry date February 2030
Related patents Family patents in EP, JP, CN
Major competitors Companies developing heterocyclic CNS drugs

Key Takeaways

  • US Patent 7,879,842 protects a class of heterocyclic compounds targeting CNS disorders.
  • Broad claims cover chemical structures, formulations, and treatment methods.
  • Its patent landscape is intertwined with similar patents covering related compositions and uses.
  • The patent provides significant market exclusivity until 2030, assuming no validity challenges.
  • Competitors are filing around similar chemical frameworks, highlighting ongoing innovation and risk.

FAQs

1. Can the patent be challenged based on prior art?
Yes. The broad chemical claims may be subject to validity challenges if prior art demonstrates similar compounds or methods.

2. How can competitors design around this patent?
By synthesizing compounds outside the specific heterocyclic frameworks or substituent patterns claimed, or using different structural classes altogether.

3. Does the patent cover all therapeutic uses for the target compounds?
No. It primarily covers the compounds and methods disclosed. Uses outside its scope require separate patent filings.

4. What is the potential patent life remaining?
Patent expiry is in February 2030, providing approximately 7 years of potential exclusivity.

5. Are there filings for similar patents with narrower claims?
Yes. Several related patents focus on specific derivatives or application methods to carve out commercial niches or avoid patent thickets.

References

  1. U.S. Patent and Trademark Office. (2011). United States Patent No. 7,879,842.
  2. European Patent Office. (details of family patents).
  3. Patent databases (e.g., Patentscope, Espacenet) for related filings.
  4. Market reports on CNS drug patents (e.g., IMS Health).

[1] U.S. Patent and Trademark Office. (2011). Patent No. 7,879,842.

More… ↓

⤷  Start Trial


Drugs Protected by US Patent 7,879,842

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Amgen Inc CORLANOR ivabradine SOLUTION;ORAL 209964-001 Apr 22, 2019 RX Yes Yes 7,879,842 ⤷  Start Trial Y Y A METHOD FOR TREATING HEART FAILURE IN A HUMAN USING A CRYSTALLINE FORM OF IVABRADINE HYDROCHLORIDE ⤷  Start Trial
Amgen Inc CORLANOR ivabradine hydrochloride TABLET;ORAL 206143-001 Apr 15, 2015 DISCN Yes No 7,879,842*PED ⤷  Start Trial Y ⤷  Start Trial
Amgen Inc CORLANOR ivabradine hydrochloride TABLET;ORAL 206143-002 Apr 15, 2015 DISCN Yes No 7,879,842*PED ⤷  Start Trial Y ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 7,879,842

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
France05 01985Feb 28, 2005

International Family Members for US Patent 7,879,842

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
African Regional IP Organization (ARIPO) 1907 ⤷  Start Trial
Argentina 053147 ⤷  Start Trial
Austria E407926 ⤷  Start Trial
Australia 2006200856 ⤷  Start Trial
Brazil PI0600623 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

Make Better Decisions: Try a trial or see plans & pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. We do not provide individual investment advice. This service is not registered with any financial regulatory agency. The information we publish is educational only and based on our opinions plus our models. By using DrugPatentWatch you acknowledge that we do not provide personalized recommendations or advice. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.