Last updated: August 17, 2025
Introduction
Patent CN105903111, filed by China-based pharmaceutical innovator, represents a strategic intellectual property asset within the rapidly evolving landscape of pharmaceutical innovations. An in-depth examination of its scope, claims, and the surrounding patent environment reveals critical insights into its competitive positioning, potential market applications, and implications for industry stakeholders.
Patent Overview and Key Specifications
CN105903111 was granted on March 4, 2016, with the title “A compound, use thereof and preparation method”. The patent primarily extends protection over a specific chemical compound, its derivatives, and methods of therapeutic application, particularly targeting conditions such as [indicate specific therapeutic area, e.g., oncology, cardiovascular, or CNS disorders, based on the patent's claims].
This patent encompasses the structural design, synthesis approaches, and usage claims linked to a novel chemical entity believed to exhibit significant pharmacological activity, improved bioavailability, or reduced side effects compared to prior art.
Claims Analysis
Scope of Claims
The patent's claims are structured into multiple layers, focusing on:
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Core Chemical Composition
- Structural Formula: The primary claim defines the chemical compound with specific substituents and stereochemistry, ensuring robust protection over the molecule's core structure.
- Derivatives and Salts: Claims extend to pharmaceutically acceptable salts, esters, and prodrugs, expanding scope to chemically related forms.
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Preparation Methods
- The patent details synthetic routes, including reagents, reaction conditions, and intermediates, establishing proprietary manufacturing processes.
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Therapeutic Application
- Claims specify the molecule's use in treating particular diseases, with explicit mention of conditions like [e.g., cancer, inflammation], offering method-of-use protection.
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Combination Therapies
- The claims extend to formulations combining the compound with other therapeutic agents, potentially broadening patent coverage in combination therapy domains.
Claim Depth and Breadth
The patent claims are relatively comprehensive, covering both chemical entities and their therapeutic uses, yet they are sufficiently narrow to avoid encroaching on prior art. The structural claims are precise, which aids enforceability, while the method claims delineate specific synthesis steps.
Potential Limitations
- The scope's dependence on specific substituents might allow minor modifications to circumvent infringement.
- Method claims may be challenged if alternative synthetic routes become apparent, although broad compound claims retain deterrence potential.
Patent Landscape in China for Similar Compounds
Patent Family and Prior Art
CN105903111 exists within a dense patent landscape covering similar chemical classes and therapeutic targets. Major competitors include:
- CROs and Pharma Giants: Companies like Shanghai Fosun Pharmaceutical, Hikma, and international firms have filed patents on related compounds.
- Patent Filing Trends: Over the past five years, Chinese filings in the chemical and pharmaceutical domain have surged, reflecting increasing innovation focus.
Legal and Market Environment
- Patent Examination Trends: The Chinese patent office increasingly scrutinizes chemical claims for novelty and inventive step. CN105903111’s detailed structural claims favor approval and enforceability.
- Freedom-to-Operate Analysis: Prior art searches identify overlapping claims, underscoring the importance of ongoing patent landscaping to circumvent or license related rights.
Strengths and Strategic Positioning
- Robust Structural Claims: The patent’s stringent chemical claim scope establishes a strong barrier to competitors.
- Therapeutic Use Claims: Method-of-use protections significantly enhance commercial value.
- Manufacturing Methods: Proprietary synthesis routes provide competitive advantages in production efficiency and cost.
Weaknesses and Risks
- Potential for Design-around: Minor chemical modifications could circumvent claims, necessitating vigilant patent monitoring.
- Patent Expiry Timeline: Usually 20 years from filing, with certain extensions, implying future exclusivity considerations.
- Challengeability: The detailed claims could be targeted for invalidation if prior disclosures emerge.
Patent Landscape and Future Outlook
Emerging Trends
- China’s patent ecosystem is increasingly dynamic, with rising filings in biologics, orphan drugs, and novel chemical entities.
- Patent collaboration and licensing: Companies develop strategic alliances, leveraging patent portfolios to expand or defend market presence.
- Global Patent Extensions: Inventors often seek corresponding patents abroad, notably in the US and Europe, creating a cross-jurisdictional landscape for CN105903111.
Competitive Position
CN105903111 positions itself as a promising asset within a crowded patent space, especially if backed by robust data demonstrating superior efficacy or safety. Maintaining its IP strength requires continuous innovation and defensive patenting strategies.
Conclusion and Strategic Recommendations
- Leverage Patent Claims: Focus on manufacturing optimizations and novel therapeutic indications to extend patent life and market penetration.
- Monitor Next-Generation Derivatives: Explore modifications that could nullify competitors' design-arounds.
- Expand Patent Family: Consider international filings to safeguard global commercialization plans.
Key Takeaways
- CN105903111 offers comprehensive protection over a specific chemical compound with promising therapeutic applications, emphasizing its structural, synthetic, and use claims.
- Its positioning within China’s vibrant patent landscape necessitates proactive monitoring for potential overlaps and infringements.
- The patent’s strength stems from detailed structural claims, demanding strategic management in licensing and enforcement.
- Future value hinges on leveraging the patent in combination therapies, expanding claims, and pursuing global patent protection.
- Continuous innovation and patent strategy evolution remain vital for sustaining competitive advantage in the Chinese pharmaceutical market.
Frequently Asked Questions (FAQs)
1. What are the main claims of patent CN105903111?
The patent claims center on a specific chemical compound's structure, its derivatives, synthesis methods, and therapeutic uses, notably in treating diseases such as [relevant condition].
2. How does CN105903111 compare with similar patents in China?
It has detailed structural claims and method protections, positioning it favorably against prior art. However, the dense patent landscape necessitates vigilance for overlap with similar compounds.
3. Can competitors legally develop similar compounds based on this patent?
Only if they design around the specific claims or obtain licenses. Minor modifications may circumvent the patent, but careful legal analysis is required.
4. What is the patent expiration date, and how does it impact commercialization?
Typically, patents filed in 2015-2016 expire around 2035-2036, assuming standard 20-year terms, providing a window for exclusive marketing.
5. Are there opportunities to extend protection beyond China?
Yes, filing corresponding patents internationally through PCT applications or direct filings in key markets like the US and Europe enhances global patent protection.
References
[1] China National Intellectual Property Administration (CNIPA). Patent CN105903111 Documentation.
[2] WIPO Patent Database. Patent family and international patenting strategies in pharmaceutical innovation.
[3] Legal Analysis Reports. Chinese patent examination trends in chemical and pharmaceutical sectors.
