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QVAR 80 Drug Profile

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Which patents cover Qvar 80, and what generic alternatives are available?

Qvar 80 is a drug marketed by Teva Branded Pharm and is included in one NDA. There are four patents protecting this drug.

This drug has one hundred and seventy-five patent family members in twenty-four countries.

The generic ingredient in QVAR 80 is beclomethasone dipropionate. There are twenty drug master file entries for this compound. Five suppliers are listed for this compound. Additional details are available on the beclomethasone dipropionate profile page.

Summary for QVAR 80

International Patents:	175
US Patents:	4
Applicants:	1
NDAs:	1
Suppliers / Packagers:	5
Bulk Api Vendors:	45
Patent Applications:	4,451
Formulation / Manufacturing:	see details
DailyMed Link:	QVAR 80 at DailyMed

Pharmacology for QVAR 80

Drug Class	Corticosteroid
Mechanism of Action	Corticosteroid Hormone Receptor Agonists

Synonyms for QVAR 80

(11beta,16beta)-9-chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione

(11beta,16beta)-9-chloro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-diene-17,21-diyl dipropanoate

[(8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(2-propanoyloxyacetyl)-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate

[2-[(8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-propanoyloxy-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] propanoate

[2-[(8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-propanoyloxy-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] propanoate

2-[(1R,2S,10S,11S,13S,14R,15S,17S)-1-chloro-17-hydroxy-2,13,15-trimethyl-5-oxo-14-(propanoyloxy)tetracyclo[8.7.0.0;{2,7}.0;{11,15}]heptadeca-3,6-dien-14-yl]-2-oxoethyl propanoate

2-[(1R,2S,10S,11S,13S,14R,15S,17S)-1-CHLORO-17-HYDROXY-2,13,15-TRIMETHYL-5-OXO-14-(PROPANOYLOXY)TETRACYCLO[8.7.0.0(2),?.0(1)(1),(1)?]HEPTADECA-3,6-DIEN-14-YL]-2-OXOETHYL PROPANOATE

32278-EP2281815A1

32278-EP2295408A1

32278-EP2301933A1

32278-EP2305640A2

32278-EP2311827A1

34135-07-4

534B098

5534-09-8

5B307S63B2

9-AE-11|A,17,21-EyoC>>u-16|A-(1/4)x>>uOEthcThorn-1,4- paragraph signthornI(c)-3,20- paragraph signthornI feminine-17,21- paragraph signthorn+/-uEao yen

9-Chloro-11.beta.,17,21-trihydroxy-16.beta.-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate

9-Chloro-11|A,17,21-trihydroxy-16|A-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate

9-Chloro-11beta-hydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate

9-Chloro-11beta, 17,21-trihydroxy-16 beta-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate

9-Chloro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate

9-chloro-16beta-methyl-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-dipropionate

AB1009261

AC-2159

AC1L2IWA

AC1Q62MZ

Aerobec

AKOS015951275

Alanase

Aldecin

Aldecina

Aldecine

Ambap5534-09-8

AN-14214

API0001601

Atomase

B4464

Beclacin

Beclate

Beclazone

Beclazone 250

Beclocort Nasel

Becloforte

Beclomet

Beclomet Nasal

Beclometasone 17,21-dipropionate

Beclometasone dipropionate

Beclometasone dipropionate (JP17)

Beclometasone dipropionate for peak identification, European Pharmacopoeia (EP) Reference Standard

Beclometasone dipropionate for system suitability, European Pharmacopoeia (EP) Reference Standard

Beclometasone dipropionato

BECLOMETHASONE DIPROPIONATE

Beclomethasone dipropionate (USP)

Beclomethasone dipropionate [USAN:USP]

Beclomethasone dipropionate [USAN]

BECLOMETHASONE DIPROPIONATE MONOHYDRATE

Beclomethasone dipropionate, analytical standard, for drug analysis

Beclomethasone dipropionate, anhydrous, European Pharmacopoeia (EP) Reference Standard

Beclomethasone Dipropionate, pharmaceutical secondary standard, traceable to USP, PhEur, BP

Beclomethasone dipropionate, United States Pharmacopeia (USP) Reference Standard

Beclorhinol

Becloturmant

Beclovent

Beclovent (TN)

Beconase

Beconase AQ

Benconase

BPBio1_000957

BRD-K97810537-001-03-7

BSPBio_000869

C07813

C28H37ClO7

CAS-5534-09-8

CCG-220855

CHEBI:3002

CHEMBL1200500

Clenil

Clenil-A

CPD001233361

CS-1503

CTK8F7938

D00689

DSSTox_CID_28656

DSSTox_GSID_48730

DSSTox_RID_82926

DTXSID3048730

EINECS 226-886-0

Entyderma

GTPL5894

HMS1570L11

HMS2097L11

HMS2235O23

HMS3259H03

HY-13571A

Inalone O

Inalone R

Korbutone

KUVIULQEHSCUHY-XYWKZLDCSA-N

KW-053

LS-118439

Menaderm

MFCD00135613

MLS002154034

MolPort-003-983-412

NC00610

NCGC00094596-03

NCGC00179392-01

PL000448

Pregna-1-4-diene-3,20-dione, 9-chloro-16-beta-methyl-11-beta,17,21-trihydroxy-,17,21-dipropionate

Pregna-1,4-diene-3,20-dione, 9-chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)-, (11.beta.,16.beta.)-

Pregna-1,4-diene-3,20-dione, 9-chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)-, (11beta,16beta)-

Pregna-1,4-diene-3,20-dione, 9-chloro-16-beta-methyl-11-beta,17,21-trihydroxy-, 17,21-dipropionate

Prestwick_990

Prestwick0_000855

Prestwick1_000855

Prestwick2_000855

Prestwick3_000855

Propaderm

Propaderm Forte

Propionic acid beclomethasone

QNASL

Qnasl (TN)

Qvar

QVAR 40

Respocort

Rhino Clenil

Rhinosol

Rino-clenil

s3078

Sanasthmax

Sanasthmyl

SCH 18020W

SCHEMBL6890

SMR001233361

SPBio_002790

Spir

ST24046007

Tox21_113168

Turbinal

UNII-5B307S63B2

Vancenase

Vanceril

Vanceril (TN)

Vanceril Double Strength

Ventolair

Viarox

W-5080

ZINC3938744

US Patents and Regulatory Information for QVAR 80

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Exclusivity Expiration
Teva Branded Pharm	QVAR 80	beclomethasone dipropionate	AEROSOL, METERED;INHALATION	020911-001	Sep 15, 2000		DISCN	Yes	No			Y
Teva Branded Pharm	QVAR 80	beclomethasone dipropionate	AEROSOL, METERED;INHALATION	020911-001	Sep 15, 2000		DISCN	Yes	No			Y
Teva Branded Pharm	QVAR 80	beclomethasone dipropionate	AEROSOL, METERED;INHALATION	020911-001	Sep 15, 2000		DISCN	Yes	No			Y
Teva Branded Pharm	QVAR 80	beclomethasone dipropionate	AEROSOL, METERED;INHALATION	020911-001	Sep 15, 2000		DISCN	Yes	No			Y

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Expired US Patents for QVAR 80

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	Patent No.	Patent Expiration
Teva Branded Pharm	QVAR 80	beclomethasone dipropionate	AEROSOL, METERED;INHALATION	020911-001	Sep 15, 2000
Teva Branded Pharm	QVAR 80	beclomethasone dipropionate	AEROSOL, METERED;INHALATION	020911-001	Sep 15, 2000
Teva Branded Pharm	QVAR 80	beclomethasone dipropionate	AEROSOL, METERED;INHALATION	020911-001	Sep 15, 2000
Teva Branded Pharm	QVAR 80	beclomethasone dipropionate	AEROSOL, METERED;INHALATION	020911-001	Sep 15, 2000
Teva Branded Pharm	QVAR 80	beclomethasone dipropionate	AEROSOL, METERED;INHALATION	020911-001	Sep 15, 2000
Teva Branded Pharm	QVAR 80	beclomethasone dipropionate	AEROSOL, METERED;INHALATION	020911-001	Sep 15, 2000
Teva Branded Pharm	QVAR 80	beclomethasone dipropionate	AEROSOL, METERED;INHALATION	020911-001	Sep 15, 2000

Non-Orange Book US Patents for QVAR 80

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No.	Title	Estimated Patent Expiration
9,731,087	Dose counter for inhaler having a bore and shaft arrangement
9,737,674	Dose counters for inhalers, inhalers and methods of assembly thereof
8,978,966	Dose counters for inhalers, inhalers and methods of assembly thereof
9,526,850	Dose counters for inhalers, inhalers and methods of assembly thereof
9,174,013	Dose counters for inhalers, inhalers and methods of assembly thereof
9,533,111	Dose counters for inhalers, inhalers and methods of assembly thereof
9,108,010	Dose counters for inhalers, inhalers and methods of assembly thereof

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International Patents for QVAR 80

Country	Document Number	Estimated Expiration
Hong Kong	1221920
World Intellectual Property Organization (WIPO)	2011144326
Croatia	P20150102
Hong Kong	1222811
South Africa	201307996
Eurasian Patent Organization	201300234
Denmark	2514465