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Last Updated: December 12, 2025

Acetic acid, glacial; aluminum acetate - Generic Drug Details


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What are the generic sources for acetic acid, glacial; aluminum acetate and what is the scope of freedom to operate?

Acetic acid, glacial; aluminum acetate is the generic ingredient in three branded drugs marketed by Bausch And Lomb, Pharmafair, and Bayer Pharms, and is included in three NDAs. Additional information is available in the individual branded drug profile pages.

Summary for acetic acid, glacial; aluminum acetate
US Patents:0
Tradenames:3
Applicants:3
NDAs:3
DailyMed Link:acetic acid, glacial; aluminum acetate at DailyMed

US Patents and Regulatory Information for acetic acid, glacial; aluminum acetate

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Pharmafair BOROFAIR acetic acid, glacial; aluminum acetate SOLUTION/DROPS;OTIC 088606-001 Aug 21, 1985 DISCN No No ⤷  Get Started Free ⤷  Get Started Free ⤷  Get Started Free
Bayer Pharms DOMEBORO acetic acid, glacial; aluminum acetate SOLUTION/DROPS;OTIC 084476-001 Approved Prior to Jan 1, 1982 DISCN Yes No ⤷  Get Started Free ⤷  Get Started Free ⤷  Get Started Free
Bausch And Lomb ACETIC ACID 2% IN AQUEOUS ALUMINUM ACETATE acetic acid, glacial; aluminum acetate SOLUTION/DROPS;OTIC 040063-001 Feb 25, 1994 DISCN No No ⤷  Get Started Free ⤷  Get Started Free ⤷  Get Started Free
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

Market Dynamics and Financial Trajectory for Acetic Acid, Glacial; Aluminum Acetate

Last updated: July 27, 2025

Introduction

The pharmaceutical sector relies heavily on a diverse array of chemicals, including acetic acid, glacial; aluminum acetate, which serve vital roles in formulation, manufacturing, and therapeutic applications. Understanding the market dynamics and financial development of these chemicals is crucial for stakeholders, from manufacturers to investors, seeking informed decisions in a competitive environment. This analysis examines the global trends, supply and demand factors, regulatory landscape, and financial trajectories influencing acetic acid, glacial; aluminum acetate, grounded in recent industry data.

Overview of Acetic Acid, Glacial; Aluminum Acetate

Acetic Acid, Glacial is a concentrated form of acetic acid (around 99-100%), characterized by its purity and clarity at room temperature. It is extensively employed in pharmaceutical manufacturing as a solvent, pH regulator, and raw material for synthesizing other compounds, notably aluminum acetate. Aluminum Acetate is a medicinal compound with a topical application for skin conditions, making pharmaceutical-grade aluminum acetate vital for skincare, wound care, and dermatological treatments.

Market Dynamics

Global Supply and Demand Framework

The pharmaceutical chemical sector has witnessed substantial growth, propelled by aging populations, increased chronic disease prevalence, and ongoing innovation in drug formulations. Acetic acid’s pharmaceutical-grade segment benefits from expanding use in drug synthesis, with the global market valued at approximately USD 1.2 billion in 2022, growing at a compound annual growth rate (CAGR) of roughly 4% (source [1]).

The demand for aluminum acetate remains comparatively niche, but steady, driven by dermatological and topical formulations. The demand correlates with the broader dermatology market, projected to reach USD 22.4 billion by 2028 at a CAGR of 4.21% (source [2]). The increasing preference for minimally invasive and topical treatments sustains steady consumption.

Production and Supply Considerations

Major industrial producers of acetic acid include China, the United States, and South Korea, accounting for roughly 60% of global output, primarily via methanol carbonylation, as per IHS Markit ([3]). The raw material costs, especially methanol prices, significantly influence production margins.

Aluminum acetate production depends on the availability of high-purity aluminum hydroxide and acetic acid. Supply chain disruptions, such as those caused by geopolitical tensions or pandemic-related logistics, have impacted raw material sourcing, influencing availability and pricing.

Pricing Trends

Acetic acid prices have been volatile, influenced by methanol prices, capacity utilization, environmental regulations, and global economic conditions. For example, in 2022, acetic acid spot prices increased by approximately 7% due to elevated methanol costs and supply constraints. Aluminum acetate's pricing remains relatively stable, often embedded within finished pharmaceutical products, with minor fluctuations influenced by raw material costs and regulatory compliance expenses.

Regulatory and Quality Standards

Stringent regulations surrounding pharmaceutical-grade chemicals impact production and market access. Regulatory compliance, including FDA approvals and Good Manufacturing Practices (GMP), elevates manufacturing costs but enhances market trust.

Market Challenges and Opportunities

Challenges:

  • Environmental regulations leading to the phased-out use of certain production methods.
  • Supply chain vulnerabilities affecting raw material availability.
  • Pricing pressures driven by commoditization and competition.

Opportunities:

  • Growing demand for topical dermatological treatments.
  • Advancements in green chemistry, offering eco-friendly production techniques.
  • Expanding pharmaceutical formulations incorporating acetic acid derivatives.

Financial Trajectory

Revenue and Profitability Outlook

The financial trajectory for acetic acid, glacial, and aluminum acetate remains positive, driven by rising pharmaceutical consumption. Projected revenues for the acetic acid segment are expected to reach USD 1.35 billion by 2025, representing a CAGR of approximately 4%. Margins are contingent on raw material costs; firms adopting more sustainable, cost-effective production methods can achieve improved profitability.

In niche markets such as aluminum acetate, revenues are comparatively modest but will benefit from increased dermatological treatment demand. Industry players with proprietary formulations and expanded regional footprints are likely to outperform.

Investment and Capital Expenditure

Investments in capacity expansion, especially in regions with favorable regulatory environments, are ongoing. For example, recent capital expenditures in China aim to increase acetic acid capacity by approximately 300,000 metric tons annually over the next two years ([4]).

Environmental compliance investments, such as emission controls and process upgrades, are increasingly prioritized, influencing short-term costs but supporting long-term financial stability.

Emerging Market Dynamics

Growing demand from Asian markets, particularly China and India, is forecasted to significantly influence market growth. These regions are characterized by their large pharmaceutical manufacturing bases and expanding healthcare infrastructure. Conversely, regulatory hurdles and geopolitical tensions may pose risks to supply chain stability.

Financial Risks and Mitigation

Price volatility of raw materials, regulatory changes, and environmental policies pose financial risks. Firms adopting strategic sourcing, vertical integration, and biotechnological innovations are better positioned to mitigate these risks. Diversification of product portfolio and geographical expansion also provide buffers against regional disruptions.

Strategic Outlook and Future Trends

The trajectory suggests steady growth driven by pharmaceutical industry expansion, technological advances, and regional market maturation. Green chemistry initiatives—aimed at reducing environmental impact—are expected to influence production economics positively. Digitalization and automation in manufacturing processes will further optimize costs and quality control.

Consolidation and M&A activities are likely to intensify, with larger chemical producers acquiring specialized firms to expand their product portfolios and geographic reach. Investment in R&D for novel formulations incorporating acetic acid derivatives is anticipated to unlock new revenue streams.

Key Takeaways

  • The global acetic acid market in pharmaceuticals is projected to grow at around 4% annually, driven by increasing drug synthesis demands and dermatological applications.
  • Supply chain stability and raw material costs significantly influence pricing and profitability; regions like China dominate production capacity.
  • Aluminum acetate remains a niche but stable segment, with growth driven by dermatology market expansion.
  • Regulatory compliance and environmental sustainability are critical factors that shape production costs and industry competitiveness.
  • Strategic investments in capacity, green chemistry, and market expansion will underpin financial growth and resilience.

Conclusion

The market dynamics for acetic acid (glacial) and aluminum acetate are characterized by steady growth, influenced by supply-demand shifts, regulatory landscapes, and technological advancements. Financially, the sector presents promising trajectories, provided firms effectively navigate raw material costs, environmental policies, and regional market opportunities. Stakeholders investing in or sourcing these chemicals must prioritize supply chain robustness, innovation, and regulatory compliance to capitalize on the projected growth and sustain competitive advantage.


FAQs

1. What factors most influence the price fluctuations of pharmaceutical-grade acetic acid?
Raw material costs, especially methanol prices, environmental compliance costs, production capacity utilization, and geopolitical factors significantly impact acetic acid pricing.

2. How is environmental regulation impacting acetic acid manufacturing?
Stricter environmental standards are prompting manufacturers to upgrade facilities, adopt greener technologies, and mitigate emissions, often increasing operational costs but fostering sustainable growth.

3. What are the main applications of aluminum acetate in pharmaceuticals?
Primarily used in topical formulations for skin conditions such as eczema, dermatitis, and minor wounds, leveraging its astringent and anti-inflammatory properties.

4. Which regions are leading in the production of pharmaceutical-grade acetic acid?
China, the United States, and South Korea dominate due to large-scale capacity and technological expertise.

5. What growth opportunities exist for companies handling acetic acid in emerging markets?
Expanding pharmaceutical manufacturing infrastructure, rising healthcare spending, and increasing prevalence of dermatological conditions present significant growth prospects.


References

[1] MarketWatch, "Global Acetic Acid Market," 2022.
[2] Grand View Research, "Dermatology Market Size," 2023.
[3] IHS Markit, "Chemical Industry Reports," 2022.
[4] Industry Today, "Capacity Expansions in China," 2023.

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