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Verapamil hydrochloride - Generic Drug Details
What are the generic sources for verapamil hydrochloride and what is the scope of verapamil hydrochloride freedom to operate?
Verapamil hydrochloride
is the generic ingredient in seven branded drugs marketed by Mylan, Recro Gainesville, Gd Searle Llc, Mt Adams, Abraxis Pharm, Bedford, Hospira, Intl Medication, Luitpold, Marsam Pharms Llc, Smith And Nephew, Solopak, Amneal Pharms Co, Exela Pharma Scs Llc, Somerset Theraps Llc, Pfizer, Apotex Corp, Cadila Pharms Ltd, Glenmark Generics, Ivax Sub Teva Pharms, Par Pharm, Pliva, Sun Pharm Inds Inc, Actavis Elizabeth, Heritage Pharms Inc, Mutual Pharm, Sun Pharm Industries, Warner Chilcott, Watson Labs, and Yaopharma Co Ltd, and is included in sixty-four NDAs. Additional information is available in the individual branded drug profile pages.There are seventeen drug master file entries for verapamil hydrochloride. Forty-two suppliers are listed for this compound.
Summary for verapamil hydrochloride
| US Patents: | 0 |
| Tradenames: | 7 |
| Applicants: | 30 |
| NDAs: | 64 |
| Drug Master File Entries: | 17 |
| Suppliers / Packagers: | 42 |
| Bulk Api Vendors: | 88 |
| Clinical Trials: | 112 |
| Patent Applications: | 3,767 |
| Formulation / Manufacturing: | see details |
| Patent Litigation and PTAB cases: | See patent lawsuits and PTAB cases for verapamil hydrochloride |
| DailyMed Link: | verapamil hydrochloride at DailyMed |
Pharmacology for verapamil hydrochloride
| Drug Class | Calcium Channel Blocker |
| Mechanism of Action | P-Glycoprotein Inhibitors Calcium Channel Antagonists Cytochrome P450 3A4 Inhibitors Cytochrome P450 3A Inhibitors |
Medical Subject Heading (MeSH) Categories for verapamil hydrochloride
Synonyms for verapamil hydrochloride
| ( inverted question mark)-Verapamil hydrochloride |
| (??)-Verapamil hydrochloride |
| (?)-Verapamil hydrochloride |
| ()-Verapamil hydrochlorid |
| (+-)-5-((3,4-Dimethoxyphenethyl)methylamino)-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile monohydrochloride |
| (+-)-Verapamil hydrochloride |
| (+/-)-VERAPAMIL HYDROCHLORIDE |
| (+/-)-Verapamil hydrochloride, >=99% (titration), powder |
| (+/-)-Verapamil hydrochloride, 99+% |
| (+/-)-Verapamil hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material |
| (+/-)-Verapamil, Hydrochloride |
| (y)-Verapamil hydrochloride |
| 152-11-4 |
| 152V114 |
| 2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methyl-amino]-2-isopropyl-pentanenitrile hydrochloride |
| 2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methyl-amino]-2-propan-2-yl-pentanenitrile hydrochloride |
| 2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile hydrochloride |
| 2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile;hydrochloride |
| 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile hydrochloride |
| 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-isopropylpentanenitrile hydrochloride |
| 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl]methylamino}-2-(methy lethyl)pentanenitrile, chloride |
| 23313-68-0 |
| 36622-29-4 |
| 5-((3,4-dimethoxyphenethyl)(methyl)amino)-2-(3,4-dimethoxyphenyl)-2-isopropylpentanenitrile hydrochloride |
| 5-((3,4-Dimethoxyphenethyl)methylamino)-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile monohydrochloride |
| 5-[(3,4-Dimethoxyphenethyl)methylamino]-2-(3,4-dimethoxy phenyl)-2-isopropylvaleronitrile hydrochloride |
| 5-[(3,4-Dimethoxyphenethyl)methylamino]-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile Hydrochloride |
| 54236-EP2305219A1 |
| 54236-EP2308562A2 |
| A816666 |
| AB0018370 |
| AC-16228 |
| AC-8483 |
| AC1L1Y4V |
| AC1Q3CE8 |
| Akilen |
| AKOS005267117 |
| AN-7969 |
| Anpec |
| API0024301 |
| Apo-Verap |
| ARONIS24174 |
| Arpamyl LP |
| AS-16018 |
| BBC/320 |
| BC210130 |
| BCP06465 |
| Benzeneacetonitrile, alpha-(3-((2-(3,4-dimethoxyphenyl)ethyl)methylamino)propyl)-3,4-dimethoxy-alpha-(1-methylethyl)-, monohydrochloride |
| Benzeneacetonitrile, alpha-(3-((2-(3,4-dimethoxyphenyl)ethyl)methylamino)propyl)-3,4-dimethoxy-alpha-(1-methylethyl)-, monohydrochloride, (+-)- |
| Benzeneacetonitrile,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-.alpha.-(1-methylethyl)-, monohydrochloride |
| Berkatens |
| BG0353 |
| BIV1326 |
| C27H38N2O4.HCl |
| C27H39ClN2O4 |
| Calan (TN) |
| Calan SR |
| Calaptin |
| Calaptin 240 SR |
| Calcan hydrochloride |
| Cardiabeltin |
| Cardiagutt |
| Cardibeltin |
| Cardioprotect |
| CAS-152-11-4 |
| Caveril |
| CC-35585 |
| CCG-39491 |
| CHEMBL1280 |
| Civicor |
| Civicor Retard |
| Coraver |
| Cordilox |
| Cordilox SR |
| Corpamil |
| Covera |
| Covera-HS |
| Covera-hs (TN) |
| CS-1685 |
| D-365 hydrochloride |
| D00619 |
| Dignover |
| Dilacoran HTA |
| DOQPXTMNIUCOSY-UHFFFAOYSA-N |
| DSSTox_CID_14095 |
| DSSTox_GSID_34095 |
| DSSTox_RID_79114 |
| DTXSID2034095 |
| Durasoptin |
| EINECS 205-800-5 |
| Elthon |
| EN300-124002 |
| EU-0101237 |
| Flamon |
| FT-0603360 |
| FT-0655647 |
| Geangin |
| Harteze |
| Hexasoptin |
| Hexasoptin Retard |
| HMS1568M04 |
| HMS1922J16 |
| Hormitol |
| HSDB 3928 |
| HY-A0064 |
| I06-0615 |
| Ikacor |
| Ikapress |
| IN1425 |
| Inselon |
| Iproveratril hydrochloride |
| Isoptin Retard |
| Isoptin SR |
| Isoptino |
| Isotopin hydrochloride |
| Izoptin |
| Jenapamil |
| K-4825 |
| Lekoptin |
| Lodixal |
| LP01237 |
| LS-161199 |
| LU 20175 |
| Magotiron |
| Manidon |
| Manidon Retard |
| MFCD00055208 |
| MLS000069485 |
| MLS001055442 |
| MLS002222213 |
| MolPort-002-915-466 |
| NCGC00024710-03 |
| NCGC00094479-01 |
| NCGC00094479-02 |
| NCGC00094479-03 |
| NCGC00094479-04 |
| NCGC00094479-05 |
| NCGC00258732-01 |
| NCGC00261922-01 |
| Novapamyl LP |
| Novo-Veramil |
| NSC 135784 |
| NSC 272366 |
| NSC-272366 |
| NSC-657799 |
| NSC-759589 |
| NSC272366 |
| NSC657799 |
| NSC759589 |
| Nu-Verap |
| Opera_ID_1210 |
| Ormil |
| Pharmakon1600-02300307 |
| Praecicor |
| Prestwick_440 |
| Q-201923 |
| Quasar |
| R853 |
| Rapam |
| Robatelan |
| s4202 |
| SC-18887 |
| SCHEMBL33296 |
| SMR000059109 |
| SPECTRUM2300307 |
| SR-01000000050 |
| SR-01000000050-11 |
| SR-01000000050-2 |
| SR-01000000050-4 |
| ST066908 |
| ST24050346 |
| SW196662-4 |
| Tox21_201180 |
| Tox21_501237 |
| Univer |
| Univex |
| V 4629 |
| Valeronitrile, 5-((3,4-dimethoxyphenethyl)methylamino)-2-(3,4-dimethoxyphenyl)-2-isopropyl-, monohydrochloride |
| Valeronitrile, 5-((3,4-dimethoxyphenethyl)methylamino)-2-(3,4-dimethoxyphenyl)-2-isopropyl-,monohydrochloride |
| Vasolan (TN) |
| Vasomil |
| Vasopten |
| Vera-Sanorania |
| Verabeta |
| Veracaps SR |
| Veracor |
| Verahexal |
| Veraloc |
| Veramex |
| Veramil |
| Verapamil (hydrochloride) |
| Verapamil Acis |
| Verapamil AL |
| Verapamil Atid |
| Verapamil Basics |
| Verapamil chloridrate |
| Verapamil Ebewe |
| Verapamil HCl |
| Verapamil Henning |
| Verapamil Hydrochloride (Isoptin, Iproveratril, Calan) |
| Verapamil hydrochloride (JP17/USP) |
| Verapamil hydrochloride [USAN:JAN] |
| Verapamil hydrochloride [USAN:USP:JAN] |
| Verapamil Hydrochloride 1.0 mg/ml in Methanol (as free base) |
| Verapamil hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material |
| Verapamil hydrochloride, European Pharmacopoeia (EP) Reference Standard |
| Verapamil hydrochloride, United States Pharmacopeia (USP) Reference Standard |
| Verapamil Hydrochloride,(S) |
| Verapamil Injection |
| Verapamil MSD |
| Verapamil NM |
| Verapamil NM Pharma |
| Verapamil Nordic |
| Verapamil PB |
| Verapamil Riker |
| Verapamil SR |
| Verapamil Verla |
| Verapamil-AbZ |
| Verapamil, HCl |
| Verapamyl hydrochloride |
| Verapin |
| Verapress 240 SR |
| Verasal |
| Verasifar |
| Veratensin |
| Verdilac |
| Verelan (TN) |
| Verelan SR |
| Veroptinstada |
| Verpamil |
| Vetrimil |
| Vortac |
| Z2210978706 |
| ZX-AFC000544 |
| ZX-AS004533 |
US Patents and Regulatory Information for verapamil hydrochloride
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Exclusivity Expiration |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ivax Sub Teva Pharms | VERAPAMIL HYDROCHLORIDE | verapamil hydrochloride | TABLET, EXTENDED RELEASE;ORAL | 073568-001 | Jul 31, 1992 | AB | RX | No | No | ➤ Sign Up | ➤ Sign Up | ➤ Sign Up | |||
| Bedford | VERAPAMIL HYDROCHLORIDE | verapamil hydrochloride | INJECTABLE;INJECTION | 072888-001 | Jul 28, 1995 | DISCN | No | No | ➤ Sign Up | ➤ Sign Up | ➤ Sign Up | ||||
| Ivax Sub Teva Pharms | VERAPAMIL HYDROCHLORIDE | verapamil hydrochloride | TABLET, EXTENDED RELEASE;ORAL | 073568-002 | Oct 10, 1997 | AB | RX | No | No | ➤ Sign Up | ➤ Sign Up | ➤ Sign Up | |||
| Luitpold | VERAPAMIL HYDROCHLORIDE | verapamil hydrochloride | INJECTABLE;INJECTION | 070225-001 | Nov 12, 1985 | DISCN | No | No | ➤ Sign Up | ➤ Sign Up | ➤ Sign Up | ||||
| Recro Gainesville | VERELAN PM | verapamil hydrochloride | CAPSULE, EXTENDED RELEASE;ORAL | 020943-001 | Nov 25, 1998 | AB | RX | Yes | No | ➤ Sign Up | ➤ Sign Up | ➤ Sign Up | |||
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Exclusivity Expiration |
Expired US Patents for verapamil hydrochloride
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | Patent No. | Patent Expiration |
|---|---|---|---|---|---|---|---|
| Gd Searle Llc | COVERA-HS | verapamil hydrochloride | TABLET, EXTENDED RELEASE;ORAL | 020552-002 | Feb 26, 1996 | ➤ Sign Up | ➤ Sign Up |
| Gd Searle Llc | COVERA-HS | verapamil hydrochloride | TABLET, EXTENDED RELEASE;ORAL | 020552-001 | Feb 26, 1996 | ➤ Sign Up | ➤ Sign Up |
| Gd Searle Llc | COVERA-HS | verapamil hydrochloride | TABLET, EXTENDED RELEASE;ORAL | 020552-002 | Feb 26, 1996 | ➤ Sign Up | ➤ Sign Up |
| Gd Searle Llc | COVERA-HS | verapamil hydrochloride | TABLET, EXTENDED RELEASE;ORAL | 020552-002 | Feb 26, 1996 | ➤ Sign Up | ➤ Sign Up |
| Gd Searle Llc | COVERA-HS | verapamil hydrochloride | TABLET, EXTENDED RELEASE;ORAL | 020552-002 | Feb 26, 1996 | ➤ Sign Up | ➤ Sign Up |
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | Patent No. | Patent Expiration |
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Preferred Citation:
Friedman, Yali. "DrugPatentWatch" DrugPatentWatch, thinkBiotech, 2019, www.DrugPatentWatch.com.
Friedman, Yali. "DrugPatentWatch" DrugPatentWatch, thinkBiotech, 2019, www.DrugPatentWatch.com.
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