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Verapamil hydrochloride - Generic Drug Details

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What are the generic sources for verapamil hydrochloride and what is the scope of verapamil hydrochloride freedom to operate?

Verapamil hydrochloride is the generic ingredient in seven branded drugs marketed by Mylan, Recro Gainesville, Gd Searle Llc, Mt Adams, Abraxis Pharm, Bedford, Hospira, Intl Medication, Luitpold, Marsam Pharms Llc, Smith And Nephew, Solopak, Exela Pharma Scs Llc, Somerset Theraps Llc, Pfizer, Apotex Corp, Cadila Pharms Ltd, Glenmark Generics, Ivax Sub Teva Pharms, Par Pharm, Pliva, Sun Pharm Inds Inc, Actavis Elizabeth, Heritage Pharms Inc, Mutual Pharm, Sun Pharm Industries, Warner Chilcott, Watson Labs, and Yaopharma Co Ltd, and is included in sixty-three NDAs. Additional information is available in the individual branded drug profile pages.

There are seventeen drug master file entries for verapamil hydrochloride. Thirty-nine suppliers are listed for this compound.

Summary for verapamil hydrochloride

US Patents:	0
Tradenames:	7
Applicants:	29
NDAs:	63
Drug Master File Entries:	17
Suppliers / Packagers:	39
Bulk Api Vendors:	80
Clinical Trials:	107
Patent Applications:	3,684
Formulation / Manufacturing:	see details
Patent Litigation and PTAB cases:	See patent lawsuits and PTAB cases for verapamil hydrochloride
DailyMed Link:	verapamil hydrochloride at DailyMed

Pharmacology for verapamil hydrochloride

Drug Class	Calcium Channel Blocker
Mechanism of Action	Calcium Channel Antagonists Cytochrome P450 3A4 Inhibitors Cytochrome P450 3A Inhibitors P-Glycoprotein Inhibitors

Medical Subject Heading (MeSH) Categories for verapamil hydrochloride

Anti-Arrhythmia Agents

Calcium Channel Blockers

Vasodilator Agents

Synonyms for verapamil hydrochloride

( inverted question mark)-Verapamil hydrochloride

(??)-Verapamil hydrochloride

(?)-Verapamil hydrochloride

(+-)-5-((3,4-Dimethoxyphenethyl)methylamino)-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile monohydrochloride

(+-)-Verapamil hydrochloride

(+/-)-VERAPAMIL HYDROCHLORIDE

(+/-)-Verapamil hydrochloride, >=99% (titration), powder

(+/-)-Verapamil hydrochloride, pharmaceutical secondary standard; traceable to USP and PhEur

(+/-)-Verapamil, Hydrochloride

(S)-(-)-Verapamil Hydrochloride

(y)-Verapamil hydrochloride

152-11-4

152V114

2-(3,4-dimethoxyphenyl)-5-[[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino]-2-isopropylpentanenitrile hydrochloride

2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methyl-amino]-2-isopropyl-pentanenitrile hydrochloride

2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methyl-amino]-2-propan-2-yl-pentanenitrile hydrochloride

2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile hydrochloride

2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile;hydrochloride

2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile hydrochloride

2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-isopropylpentanenitrile hydrochloride

2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl]methylamino}-2-(methy lethyl)pentanenitrile, chloride

23313-68-0

36622-29-4

38176-10-2

5-((3,4-dimethoxyphenethyl)(methyl)amino)-2-(3,4-dimethoxyphenyl)-2-isopropylpentanenitrile hydrochloride

5-((3,4-Dimethoxyphenethyl)methylamino)-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile monohydrochloride

5-[(3,4-Dimethoxyphenethyl)methylamino]-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile Hydrochloride

54236-EP2305219A1

54236-EP2308562A2

A816666

AB0018370

AC-16228

AC-8483

AC1L1Y4V

AC1Q3CE8

Akilen

AKOS005267117

AN-7969

Anpec

API0024301

Apo-Verap

ARONIS24174

Arpamyl LP

AS-16018

BBC/320

BC210130

Benzeneacetonitrile, alpha-(3-((2-(3,4-dimethoxyphenyl)ethyl)methylamino)propyl)-3,4-dimethoxy-alpha-(1-methylethyl)-, monohydrochloride

Benzeneacetonitrile, alpha-(3-((2-(3,4-dimethoxyphenyl)ethyl)methylamino)propyl)-3,4-dimethoxy-alpha-(1-methylethyl)-, monohydrochloride, (+-)-

Benzeneacetonitrile,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-.alpha.-(1-methylethyl)-, monohydrochloride

Berkatens

BG0353

BIV1326

C27H38N2O4.HCl

C27H39ClN2O4

Calan (TN)

Calan SR

Calaptin

Calaptin 240 SR

Calcan hydrochloride

Cardiabeltin

Cardiagutt

Cardibeltin

Cardioprotect

CAS-152-11-4

Caveril

CC-35585

CCG-39491

CHEMBL1280

Civicor

Civicor Retard

Coraver

Cordilox SR

Corpamil

Covera

Covera-HS

Covera-hs (TN)

CS-1685

D-365 hydrochloride

D00619

Dignover

Dilacoran HTA

DOQPXTMNIUCOSY-UHFFFAOYSA-N

DSSTox_CID_14095

DSSTox_GSID_34095

DSSTox_RID_79114

DTXSID2034095

Durasoptin

EINECS 205-800-5

Elthon

EN300-124002

EU-0101237

Falicard

Finoptin

Flamon

FT-0603360

FT-0655647

Geangin

Harteze

Hexasoptin

Hexasoptin Retard

HMS1568M04

HMS1922J16

Hormitol

HSDB 3928

HY-A0064

I06-0615

Ikacor

Ikapress

IN1425

Inselon

Iproveratril hydrochloride

Isoptin Retard

Isoptin SR

Isoptine

Isoptino

Isotopin hydrochloride

Izoptin

Jenapamil

K-4825

Lekoptin

Lodixal

LP01237

LS-161199

LU 20175

Magotiron

Manidon

Manidon Retard

MFCD00055208

MLS000069485

MLS001055442

MLS002222213

MolPort-002-915-466

NCGC00024710-03

NCGC00094479-01

NCGC00094479-02

NCGC00094479-03

NCGC00094479-04

NCGC00094479-05

NCGC00258732-01

NCGC00261922-01

Novapamyl LP

Novo-Veramil

NSC 135784

NSC 272366

NSC-272366

NSC-657799

NSC-759589

NSC272366

NSC657799

NSC759589

Nu-Verap

Opera_ID_1210

OR075078

OR245357

Ormil

Pharmakon1600-02300307

Praecicor

Prestwick_440

Q-201923

Quasar

R(+)-VERAPAMIL

R853

Rapam

Robatelan

s4202

SC-18887

SCHEMBL33296

SMR000059109

SPECTRUM2300307

ST066908

ST24050346

Tox21_201180

Tox21_501237

Univex

V 4629

Valeronitrile, 5-((3,4-dimethoxyphenethyl)methylamino)-2-(3,4-dimethoxyphenyl)-2-isopropyl-, monohydrochloride

Valeronitrile, 5-((3,4-dimethoxyphenethyl)methylamino)-2-(3,4-dimethoxyphenyl)-2-isopropyl-,monohydrochloride

Vasolan (TN)

Vasomil

Vasopten

Vera-Sanorania

VERA? HYDROCHLORIDE

Verabeta

Veracaps SR

Veracor

Verahexal

Veraloc

Veramex

Veramil

Verapamil (hydrochloride)

Verapamil Acis

Verapamil AL

Verapamil Atid

Verapamil Basics

Verapamil chloridrate

Verapamil Ebewe

Verapamil HCl

Verapamil Henning

Verapamil Hydrochloride (Isoptin, Iproveratril, Calan)

Verapamil hydrochloride (JP17/USP)

Verapamil hydrochloride [USAN:JAN]

Verapamil hydrochloride [USAN:USP:JAN]

Verapamil Hydrochloride 1.0 mg/ml in Methanol (as free base)

Verapamil hydrochloride, European Pharmacopoeia (EP) Reference Standard

Verapamil hydrochloride, United States Pharmacopeia (USP) Reference Standard

Verapamil Injection

Verapamil MSD

Verapamil NM

Verapamil NM Pharma

Verapamil Nordic

Verapamil PB

Verapamil Riker

Verapamil SR

Verapamil Verla

Verapamil-AbZ

VERAPAMILHYDROCHLORIDE

Verapamyl hydrochloride

Verapin

Verapress 240 SR

Verasal

Verasifar

Veratensin

Verdilac

Verelan (TN)

Verelan SR

Veroptinstada

Verpamil

Vetrimil

Vortac

Z2210978706

ZX-AFC000544

ZX-AS004533

US Patents and Regulatory Information for verapamil hydrochloride

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Exclusivity Expiration
Hospira	VERAPAMIL HYDROCHLORIDE	verapamil hydrochloride	SOLUTION;INTRAVENOUS	070737-002	May 6, 1987	AP	RX	No	Yes
Mylan	VERAPAMIL HYDROCHLORIDE	verapamil hydrochloride	CAPSULE, EXTENDED RELEASE;ORAL	075138-001	Apr 20, 1999	AB	RX	No	No
Watson Labs	VERAPAMIL HYDROCHLORIDE	verapamil hydrochloride	TABLET;ORAL	072799-001	Apr 28, 1989		DISCN	No	No
Hospira	VERAPAMIL HYDROCHLORIDE	verapamil hydrochloride	INJECTABLE;INJECTION	070577-001	Feb 2, 1987		DISCN	No	No

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Expired US Patents for verapamil hydrochloride

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	Patent No.	Patent Expiration
Gd Searle Llc	COVERA-HS	verapamil hydrochloride	TABLET, EXTENDED RELEASE;ORAL	020552-001	Feb 26, 1996
Gd Searle Llc	COVERA-HS	verapamil hydrochloride	TABLET, EXTENDED RELEASE;ORAL	020552-002	Feb 26, 1996
Gd Searle Llc	COVERA-HS	verapamil hydrochloride	TABLET, EXTENDED RELEASE;ORAL	020552-001	Feb 26, 1996
Gd Searle Llc	COVERA-HS	verapamil hydrochloride	TABLET, EXTENDED RELEASE;ORAL	020552-002	Feb 26, 1996

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