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Generated: June 21, 2018

DrugPatentWatch Database Preview

Metolazone - Generic Drug Details

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What are the generic drug sources for metolazone and what is the scope of metolazone freedom to operate?

Metolazone
is the generic ingredient in four branded drugs marketed by Gd Searle Llc, Mylan, Roxane, Sandoz, Teva, Watson Labs, and Lannett Co Inc, and is included in eleven NDAs. Additional information is available in the individual branded drug profile pages.

There are nine drug master file entries for metolazone. Eleven suppliers are listed for this compound.
Pharmacology for metolazone
Drug ClassThiazide-like Diuretic
Physiological EffectIncreased Diuresis
Medical Subject Heading (MeSH) Categories for metolazone
Synonyms for metolazone
(non-labelled)Metolazone-d7
17560-51-9
2-Methyl-3-o-tolyl-6-sulfamyl-7-chloro-1,2,3,4-tetrahydro-4-quinazolinone
4CA-0814
5-25-09-00212 (Beilstein Handbook Reference)
560M519
56436-31-8
56436-32-9
6-Quinazolinesulfonamide, 1,2,3,4-tetrahydro-7-chloro-2-methyl-4-oxo-3-o-tolyl-
6-Quinazolinesulfonamide, 7-chloro-1,2,3,4-tetrahydro- 2-methyl-3-(2-methylphenyl)-4-oxo-
6-Quinazolinesulfonamide, 7-chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-
6-Quinazolinesulfonamide, 7-chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-, (-)-
6-Quinazolinesulfonamide, 7-chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-, (+)-
6-Quinazolinesulfonamide, 7-chloro-1,2,3,4-tetrahydro-2-methyl-4-oxo-3-o-tolyl-
7-Chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-6-quinazolinesulfonamide
7-Chloro-1,2,3,4-tetrahydro-2-methyl-4-oxo-3-o-tolyl-6-quinazolinesulfonamide
7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2-dihydroquinazoline-6-sulfonamide
7-Chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4-tetrahydro-6-quinazolinesulfonamide #
7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide
7-chloro-2-methyl-3-(o-tolyl)-4-oxo-1,2-dihydroquinazoline-6-sulfonamide
7-Chloro-2-methyl-4-oxo-3-(o-tolyl)-1,2,3,4-tetrahydroquinazoline-6-sulfonamide
7-Chloro-2-methyl-4-oxo-3-(o-tolyl)-1,2,3,4-tetrahydroquizoline-6-sulfomide
AB00052055
AB00052055_09
AB00052055_10
AB00052055-08
AB0012835
AB2000160
ABP000634
AC1L1HKJ
AK-61046
AKOS015897109
AN-11710
ANW-46001
API0003352
AQCHWTWZEMGIFD-UHFFFAOYSA-N
AS-13016
AX8140044
BCP9000920
BCPP000166
BDBM25899
BPBio1_000138
BRD-A61793559-001-05-7
BRN 0965506
BSPBio_000124
BSPBio_002422
C-21013
CAS-17560-51-9
CC-30932
CCG-39450
CHEBI:64354
CHEMBL878
CS-2150
CTK8B4741
D00431
D01WLC
DB00524
Diulo
DivK1c_000275
DR001977
DSSTox_CID_25167
DSSTox_GSID_45167
DSSTox_RID_80717
DTXSID6045167
EBD54305
EINECS 241-539-3
FT-0628932
GTPL4838
H024
HE318837
HMS1568G06
HMS1922L16
HMS2093P14
HMS2095G06
HMS2230J15
HMS3261J22
HMS3373C11
HMS3655M09
HMS500N17
HSDB 3367
HY-B0209
IDI1_000275
KB-249688
KBio1_000275
KBio2_000936
KBio2_003504
KBio2_006072
KBioGR_000897
KBioSS_000936
KS-00000ZJQ
KS-5139
LP00610
LS-140226
Metalazone
Metalozone
Metenix
Metolazon
Metolazona
Metolazona [INN-Spanish]
Metolazone (JAN/USP/INN)
metolazone (product)
Metolazone (Zaroxolyn)
Metolazone [USAN:BAN:INN:JAN]
Metolazone for system suitability, European Pharmacopoeia (EP) Reference Standard
Metolazone, (-)-
Metolazone, (+)-
Metolazone, >=98% (HPLC), solid
Metolazone, European Pharmacopoeia (EP) Reference Standard
Metolazone, United States Pharmacopeia (USP) Reference Standard
Metolazone(Zaroxolyn)
Metolazone(Zaroxolyn)/
Metolazonum
Metolazonum [INN-Latin]
metozalone
MFCD00069304
Microx
MLS002153316
MLS002154200
MolPort-003-666-780
Mykrox
Mykrox (TN)
Mykrox, Zaroxolyn, Diulo, Metolazone
Mykrox;Zaroxolyn;Diulo;Zaroxolyn
NCGC00093985-01
NCGC00093985-02
NCGC00093985-03
NCGC00093985-04
NCGC00093985-05
NCGC00093985-06
NCGC00093985-07
NCGC00093985-08
NCGC00093985-10
NCGC00093985-11
NCGC00261295-01
NINDS_000275
NM7V2Y3G0U
NN9U607695
NSC-759581
NSC759581
Oldren
OR285762
Pharmakon1600-02300325
Prestwick_333
Prestwick0_000112
Prestwick1_000112
Prestwick2_000112
Prestwick3_000112
Q-201399
s1610
SBI-0051460.P002
SCHEMBL40558
SMR001230730
SPBio_001842
SPBio_002063
Spectrum_000456
Spectrum2_001741
SPECTRUM2300325
Spectrum4_000229
Spectrum5_001237
SR 720-22
SR-05000001765
SR-05000001765-7
SR-720-22
SR72022
ST24029920
TC-134746
Tox21_110186
Tox21_110186_1
Tox21_113526
Tox21_500610
UNII-NM7V2Y3G0U
UNII-NN9U607695
Xuret
Zaroxolyn
Zaroxolyn (TN)

US Patents and Regulatory Information for metolazone

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Mylan METOLAZONE metolazone TABLET;ORAL 076698-003 Oct 19, 2004 AB RX No No ➤ Sign Up ➤ Sign Up ➤ Sign Up
Roxane METOLAZONE metolazone TABLET;ORAL 076482-002 Apr 29, 2004 DISCN No No ➤ Sign Up ➤ Sign Up ➤ Sign Up
Lannett Co Inc ZAROXOLYN metolazone TABLET;ORAL 017386-003 Approved Prior to Jan 1, 1982 AB RX Yes Yes ➤ Sign Up ➤ Sign Up ➤ Sign Up
Lannett Co Inc ZAROXOLYN metolazone TABLET;ORAL 017386-002 Approved Prior to Jan 1, 1982 AB RX Yes Yes ➤ Sign Up ➤ Sign Up ➤ Sign Up
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Farmers Insurance
Fuji
Deloitte
McKinsey
Harvard Business School
Merck
Express Scripts
Covington
UBS

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