You’re using a public version of DrugPatentWatch with 5 free searches available | Register to unlock more free searches. CREATE FREE ACCOUNT

Last Updated: April 18, 2024

OXYMETAZOLINE HYDROCHLORIDE - Generic Drug Details

✉ Email this page to a colleague

« Back to Dashboard

What are the generic sources for oxymetazoline hydrochloride and what is the scope of patent protection?

Oxymetazoline hydrochloride is the generic ingredient in six branded drugs marketed by Taro, Mayne Pharma, Bayer Healthcare Llc, Rvl Pharms, Johnson And Johnson, and St Renatus, and is included in six NDAs. There are twenty-two patents protecting this compound. Additional information is available in the individual branded drug profile pages.

Oxymetazoline hydrochloride has seventy-three patent family members in thirty countries.

There is one drug master file entry for oxymetazoline hydrochloride. Three suppliers are listed for this compound.

Summary for OXYMETAZOLINE HYDROCHLORIDE

International Patents:	73
US Patents:	22
Tradenames:	6
Applicants:	6
NDAs:	6
Drug Master File Entries:	1
Finished Product Suppliers / Packagers:	3
Raw Ingredient (Bulk) Api Vendors:	68
Clinical Trials:	50
Patent Applications:	3,453
Formulation / Manufacturing:	see details
Patent Litigation and PTAB cases:	See patent lawsuits and PTAB cases for OXYMETAZOLINE HYDROCHLORIDE
What excipients (inactive ingredients) are in OXYMETAZOLINE HYDROCHLORIDE?	OXYMETAZOLINE HYDROCHLORIDE excipients list
DailyMed Link:	OXYMETAZOLINE HYDROCHLORIDE at DailyMed

Recent Clinical Trials for OXYMETAZOLINE HYDROCHLORIDE

Identify potential brand extensions & 505(b)(2) entrants

Sponsor	Phase
Rigshospitalet, Denmark	Phase 4
University of Alabama at Birmingham	Phase 4
University of South Florida	Phase 4

See all OXYMETAZOLINE HYDROCHLORIDE clinical trials

Pharmacology for OXYMETAZOLINE HYDROCHLORIDE

Drug Class	Vasoconstrictor
Physiological Effect	Increased Sympathetic Activity Vasoconstriction

Medical Subject Heading (MeSH) Categories for OXYMETAZOLINE HYDROCHLORIDE

Adrenergic alpha-Agonists
Nasal Decongestants
Sympathomimetics

Paragraph IV (Patent) Challenges for OXYMETAZOLINE HYDROCHLORIDE

Tradename	Dosage	Ingredient	Strength	NDA	ANDAs Submitted	Submissiondate
RHOFADE	Topical Cream	oxymetazoline hydrochloride	1%	208552	1	2019-06-20

US Patents and Regulatory Information for OXYMETAZOLINE HYDROCHLORIDE

+ Get email alerts for changes to this table

Glossary

Subscribe to access the full database, or Try a Trial
Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Exclusivity Expiration
Mayne Pharma	RHOFADE	oxymetazoline hydrochloride	CREAM;TOPICAL	208552-001	Jan 18, 2017		RX	Yes	Yes	⤷ Try a Trial	⤷ Try a Trial				⤷ Try a Trial
St Renatus	KOVANAZE	oxymetazoline hydrochloride; tetracaine hydrochloride	SPRAY, METERED;NASAL	208032-001	Jun 29, 2016		RX	Yes	Yes	⤷ Try a Trial	⤷ Try a Trial	Y			⤷ Try a Trial
Taro	OXYMETAZOLINE HYDROCHLORIDE	oxymetazoline hydrochloride	CREAM;TOPICAL	213584-001	Oct 4, 2021		DISCN	No	No	⤷ Try a Trial	⤷ Try a Trial				⤷ Try a Trial
Rvl Pharms	UPNEEQ	oxymetazoline hydrochloride	SOLUTION/DROPS;OPHTHALMIC	212520-001	Jul 8, 2020		RX	Yes	Yes	⤷ Try a Trial	⤷ Try a Trial	Y			⤷ Try a Trial
>Applicant	>Tradename	>Generic Name	>Dosage	>NDA	>Approval Date	>TE	>Type	>RLD	>RS	>Patent No.	>Patent Expiration	>Product	>Substance	>Delist Req.	>Exclusivity Expiration

Expired US Patents for OXYMETAZOLINE HYDROCHLORIDE

Subscribe to access the full database, or Try a Trial
Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	Patent No.	Patent Expiration
Mayne Pharma	RHOFADE	oxymetazoline hydrochloride	CREAM;TOPICAL	208552-001	Jan 18, 2017	⤷ Try a Trial	⤷ Try a Trial
>Applicant	>Tradename	>Generic Name	>Dosage	>NDA	>Approval Date	>Patent No.	>Patent Expiration

International Patents for OXYMETAZOLINE HYDROCHLORIDE

Subscribe to access the full database, or Try a Trial
Country	Patent Number	Title	Estimated Expiration
Spain	2796871		⤷ Try a Trial
Morocco	55895	COMPOSITIONS D'OXYMÉTAZOLINE ET PROCÉDÉS DE TRAITEMENT DE TROUBLES OCULAIRES	⤷ Try a Trial
Peru	20220384	COMPOSICIONES Y METODOS DE OXIMETAZOLINA PARA EL TRATAMIENTO DE TRASTORNOS OCULARES	⤷ Try a Trial
European Patent Office	2680829	COMPOSITIONS ET UTILISATIONS POUR LE TRAITEMENT NON-CHIRURGICAL DE LA PTOSIS (COMPOSITIONS AND METHODS FOR NON-SURGICAL TREATMENT OF PTOSIS)	⤷ Try a Trial
>Country	>Patent Number	>Title	>Estimated Expiration

Make Better Decisions: Try a trial or see plans & pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.