DrugPatentWatch Database Preview

SAVELLA Drug Profile

« Back to Dashboard

When do Savella patents expire, and when can generic versions of Savella launch?

Savella is a drug marketed by Allergan Sales Llc and is included in one NDA. There are four patents protecting this drug and one Paragraph IV challenge.

This drug has forty-eight patent family members in twenty-six countries.

The generic ingredient in SAVELLA is milnacipran hydrochloride. There are twenty-eight drug master file entries for this compound. Five suppliers are listed for this compound. Additional details are available on the milnacipran hydrochloride profile page.

Summary for SAVELLA

International Patents:	48
US Patents:	4
Applicants:	1
NDAs:	1
Suppliers / Packagers:	4
Bulk Api Vendors:	48
Clinical Trials:	21
Patent Applications:	294
Formulation / Manufacturing:	see details
Drug Prices:	Drug price information for SAVELLA
Patent Litigation and PTAB cases:	See patent lawsuits and PTAB cases for SAVELLA
DailyMed Link:	SAVELLA at DailyMed

See drug prices for SAVELLA

See drug sales revenues for SAVELLA

Recent Clinical Trials for SAVELLA

Identify potential brand extensions & 505(b)(2) entrants

Sponsor	Phase
University of Ottawa	Phase 4
Allergan	Phase 4
Spencer Dorn, MD, MPH	Phase 2

See all SAVELLA clinical trials

Recent Litigation for SAVELLA

Identify potential future generic entrants

District Court Litigation

Case Name	Date
FOREST LABORATORIES HOLDINGS, LTD. v. STRIDES PHARMA GLOBAL PTE LIMITED	2017-10-06
Forest Laboratories Holdings, Ltd. v. Strides Pharma Global PTE Limited	2017-10-05
Forest Laboratories Inc. v. Par Pharmaceutical Inc.	2013-09-23

See all SAVELLA litigation

Pharmacology for SAVELLA

Drug Class	Serotonin and Norepinephrine Reuptake Inhibitor
Mechanism of Action	Norepinephrine Uptake Inhibitors Serotonin Uptake Inhibitors

Synonyms for SAVELLA

(+-)-cis-2-Aminomethyl-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride

(1R-cis)-Milnacipran Hydrochloride

(1R,2S)-2-(aminomethyl)-N,N-diethyl-1-phenyl-cyclopropanecarboxamide hydrochloride

(1R,2S)-2-(aminomethyl)-N,N-diethyl-1-phenylcyclopropane-1-carboxamide hydrochloride

(1R,2S)-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide Hydrochloride

(1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride

(1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide monohydrochloride

(1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide monohydrochloride; F 2207; Midalcipran; Toledomin

(1RS,2SR)-2-(aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride

(1S-cis)-Milnacipran Hydrochloride

(1S,2R)-2-(aminomethyl)-N,N-diethyl-1-phenylcyclopropane-1-carboxamide hydrochloride

(1S,2R)-2-(aminomethyl)-N,N-diethyl-1-phenylcyclopropane-1-carboxamide;hydrochloride

(1S,2R)-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide Hydrochloride

(1S,2R)-Milnacipran Hydrochloride

(Z)-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride

1-Phenyl-1-(diethylaminocarbonyl)-2-(aminomethyl)cyclopropane hydrochloride

101152-94-7

152M947

175131-60-9

175131-61-0

371U2ZK31U

86181-08-0

AB0108218

AB1004578

AC1L4TFV

AC1OCEN6

AK481450

AKOS015950801

AKOS025311514

AN-14832

AOB6178

API0003393

AS-12868

AT-28508

BC219330

BCP05817

C15H22N2O.HCl

CAS-101152-94-7

CCG-101034

CCG-231710

CHEBI:31854

CHEMBL1237129

CHEMBL2105732

cis-(-)-Milnacipran Hydrochloride

cis-(+-)-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide monohydrochloride

cis-(+)-Milnacipran Hydrochloride

cis-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide Hydrochloride

CPD000449266

CS-2010

CS-4972

Cyclopropanecarboxamide, 2-(aminomethyl)-N,N-diethyl-1-phenyl-, (Z)-, monohydrochloride

Cyclopropanecarboxamide, 2-(aminomethyl)-N,N-diethyl-1-phenyl-, monohydrochloride, (1R,2S)-rel-

Cyclopropanecarboxamide, 2-(aminomethyl)-N,N-diethyl-1-phenyl-, monohydrochloride, cis-(+-)-

D01107

D10133

Dalcipran

DSSTox_CID_26785

DSSTox_GSID_46785

DSSTox_RID_81903

DTXSID4046785

F 2207

F 2695 hydrochloride

F-2207

F2207

Fetzima

Fetzima (TN)

HY-B0168A

HY-B0168B

Ixel

J-011063

J10386

Joncia

K-0218

KS-1274

Levomilnacipran HCl

LEVOMILNACIPRAN HYDROCHLORIDE

Levomilnacipran hydrochloride (USAN)

Levomilnacipran hydrochloride [USAN]

LS-58540

LS-58541

M2133

MFCD00901293

Midalcipran hydrochloride

Milnacipran ((1S-cis) hydrochloride)

Milnacipran (hydrochloride)

Milnacipran HCl

Milnacipran hydrochloride

Milnacipran hydrochloride (JAN/USAN)

Milnacipran hydrochloride [USAN]

Milnacipran Hydrochloride 1.0 mg/ml in Methanol (as free base)

Milnacipran hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material

Milnacipran hydrochloride, >=98% (HPLC), solid

MLS000758229

MLS001424149

MolPort-005-940-369

MolPort-019-939-251

NC00284

NCGC00168780-01

rac-Milnacipran Hydrochloride

s3140

SAM001247035

Savella (TN)

SB17448

SC-15864

SCHEMBL1148742

SCHEMBL161558

SMR000449266

SW197664-2

TN-912

Toledomin

Toledomin (TN)

Tox21_112641

UNII-371U2ZK31U

UNII-RNZ43O5WW5 component XNCDYJFPRPDERF-NQQJLSKUSA-N

UNII-RNZ43O5WW5 component XNCDYJFPRPDERF-PBCQUBLHSA-N

Z-2 Aminomethyl-1-phenyl-N,N-diethylcyclopropane-carboxamide hydrochloride

Paragraph IV (Patent) Challenges for SAVELLA

Tradename	Dosage	Ingredient	NDA	Submissiondate
SAVELLA	TABLET;ORAL	milnacipran hydrochloride	022256	2013-01-14

US Patents and Regulatory Information for SAVELLA

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Exclusivity Expiration
Allergan Sales Llc	SAVELLA	milnacipran hydrochloride	TABLET;ORAL	022256-001	Jan 14, 2009		RX	Yes	No
Allergan Sales Llc	SAVELLA	milnacipran hydrochloride	TABLET;ORAL	022256-002	Jan 14, 2009		RX	Yes	No
Allergan Sales Llc	SAVELLA	milnacipran hydrochloride	TABLET;ORAL	022256-001	Jan 14, 2009		RX	Yes	No

International Patents for SAVELLA

Country	Patent Number	Estimated Expiration
World Intellectual Property Organization (WIPO)	03039598
European Patent Office	1928446
Japan	2015134811