NITROLINGUAL PUMPSPRAY Drug Patent Profile

Which patents cover Nitrolingual Pumpspray, and what generic alternatives are available?

Nitrolingual Pumpspray is a drug marketed by Pohl Boskamp and is included in one NDA. There is one patent protecting this drug and one Paragraph IV challenge.

This drug has seven patent family members in seven countries.

The generic ingredient in NITROLINGUAL PUMPSPRAY is nitroglycerin. There are thirty-six drug master file entries for this compound. Thirty-eight suppliers are listed for this compound. Additional details are available on the nitroglycerin profile page.

DrugPatentWatch^® Litigation and Generic Entry Outlook for Nitrolingual Pumpspray

A generic version of NITROLINGUAL PUMPSPRAY was approved as nitroglycerin by AM REGENT on May 24^th, 1988.

Summary for NITROLINGUAL PUMPSPRAY

International Patents:	7
US Patents:	1
Applicants:	1
NDAs:	1
Finished Product Suppliers / Packagers:	5
Raw Ingredient (Bulk) Api Vendors:	36
Patent Applications:	3,038
Drug Prices:	Drug price information for NITROLINGUAL PUMPSPRAY
DailyMed Link:	NITROLINGUAL PUMPSPRAY at DailyMed

See drug prices for NITROLINGUAL PUMPSPRAY

See drug sales revenues for NITROLINGUAL PUMPSPRAY

Pharmacology for NITROLINGUAL PUMPSPRAY

Drug Class	Nitrate Vasodilator
Physiological Effect	Vasodilation

Paragraph IV (Patent) Challenges for NITROLINGUAL PUMPSPRAY

Tradename	Dosage	Ingredient	Strength	NDA	ANDAs Submitted	Submissiondate
NITROLINGUAL PUMPSPRAY	Sublingual Spray	nitroglycerin	400 mcg/spray, 4.9 g and 12 g bottles	018705	1	2012-04-17

US Patents and Regulatory Information for NITROLINGUAL PUMPSPRAY

NITROLINGUAL PUMPSPRAY is protected by one US patents.

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Exclusivity Expiration
Pohl Boskamp	NITROLINGUAL PUMPSPRAY	nitroglycerin	SPRAY, METERED;SUBLINGUAL	018705-002	Jan 10, 1997	AB	RX	Yes	Yes	7,872,049		Y

Expired US Patents for NITROLINGUAL PUMPSPRAY

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	Patent No.	Patent Expiration
Pohl Boskamp	NITROLINGUAL PUMPSPRAY	nitroglycerin	SPRAY, METERED;SUBLINGUAL	018705-002	Jan 10, 1997	5,186,925

International Patents for NITROLINGUAL PUMPSPRAY

See the table below for patents covering NITROLINGUAL PUMPSPRAY around the world.

Country	Patent Number	Title	Estimated Expiration
Germany	59106106
Spain	2075908
Russian Federation	2010142023	ДЛИТЕЛЬНО СТАБИЛЬНАЯ ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ С АКТИВНЫМ ВЕЩЕСТВОМ ГЛИЦЕРОЛ ТРИНИТРАТОМ

Market Dynamics and Financial Trajectory for Nitrolingual Pumpspray

Introduction

Nitrolingual Pumpspray, a formulation of nitroglycerin, is a crucial medication for the acute relief and prophylaxis of angina pectoris in patients with coronary artery disease. Here, we delve into the market dynamics and financial trajectory of this drug.

Market Overview

The global medical nitroglycerin sprays market, which includes Nitrolingual Pumpspray, is anticipated to experience steady growth over the next decade. As of 2023, the market is projected to reach a valuation of USD 110.9 million, with a forecasted value of USD 163.5 million by 2033, growing at a Compound Annual Growth Rate (CAGR) of 3.9% from 2023 to 2033[1][4].

Key Growth Drivers

Increasing Prevalence of Cardiovascular Diseases

The rising prevalence of angina pectoris and other cardiovascular diseases is a significant driver for the growth of the nitroglycerin sprays market. As lifestyles become more sedentary and stress levels increase, the incidence of cardiovascular conditions is on the rise, propelling the demand for nitroglycerin-based treatments[1][3].

Ease of Use and Accessibility

Nitroglycerin sprays, such as Nitrolingual Pumpspray, are economical and easily accessible, making them a preferred option for patients. This ease of use contributes to the market's growth as more patients opt for these convenient formulations[4].

Prophylactic Use

Nitroglycerin sprays can be used not only to relieve angina attacks but also as a prophylactic measure before engaging in activities that may trigger these attacks. This dual functionality enhances their appeal and drives market growth[2][4].

Market Challenges

Side Effects and Resistance

Despite the benefits, nitroglycerin sprays come with potential side effects, such as migraines, which can restrain market growth. Additionally, the resistance of nitroglycerin to microvascular angina and its impact on blood pressure are significant challenges that need to be addressed[1][4].

Regional Market Analysis

The market for nitroglycerin sprays is diverse and spans several regions:

North America

In the United States, the market is expected to grow at a CAGR of 4.1% from 2023 to 2033, reaching a valuation of USD 63.1 million by 2033. Canada also shows a positive growth trend, albeit at a slightly lower CAGR[1].

Europe

Countries like Germany and the United Kingdom are significant contributors to the European market. Germany, for instance, is expected to see a CAGR of 4.3% from 2023 to 2033, with a forecasted valuation of USD 11.5 million by 2033[1].

Asia Pacific

The Asia Pacific region, particularly China, is expected to grow at a CAGR of 4.0% from 2023 to 2033, reaching a valuation of USD 11.1 million by 2033. This region's growth is driven by increasing awareness of cardiovascular health and advancements in healthcare infrastructure[1].

Competitive Landscape

The market for nitroglycerin sprays is competitive, with several key players investing in research and development, mergers and acquisitions, and innovative production methods.

Key Players

• G-Pohl-Boskamp GmbH & Co.: A German pharmaceutical manufacturer known for its Nitrolingual Pumpspray, available in 60 and 200 metered sprays per container[4].
• Perrigo: Received FDA approval for a generic version of Nitrolingual Pumpspray in 2013, expanding the market's competitive landscape[5].

Financial Performance

Historical Data

The global medical nitroglycerin sprays market recorded a valuation of USD 106.3 million in 2022, with a CAGR of 3.8% from 2018 to 2022[1].

Forecast

By 2033, the market is expected to reach USD 163.5 million, growing at a CAGR of 3.9% from 2023 to 2033. This growth is driven by increasing demand for nitroglycerin-based treatments and the expanding reach of these products in various regions[1][4].

Impact of COVID-19

The COVID-19 pandemic initially disrupted the global supply chain and manufacturing processes, leading to a temporary decrease in production and availability of nitroglycerin API. However, as the pandemic progressed, the demand for nitroglycerin API surged, particularly in the healthcare sector, leading to a gradual recovery of the market[3].

Future Outlook

The nitroglycerin sprays market is poised for continued growth, driven by ongoing research and development, increasing investments in healthcare infrastructure, and growing awareness about cardiovascular health. Despite challenges such as side effects and resistance, the market is expected to stabilize and continue its growth trajectory[1][3][4].

Key Takeaways

• The global medical nitroglycerin sprays market is expected to grow at a CAGR of 3.9% from 2023 to 2033.
• The market is driven by the increasing prevalence of cardiovascular diseases and the ease of use of nitroglycerin sprays.
• Regional markets, such as North America, Europe, and Asia Pacific, are expected to contribute significantly to the market's growth.
• Key players are investing in R&D and innovative production methods to gain a competitive edge.
• The market faced temporary disruptions due to COVID-19 but has shown a gradual recovery.

FAQs

What is the primary use of Nitrolingual Pumpspray?

Nitrolingual Pumpspray is primarily used for the acute relief and prophylaxis of angina pectoris in patients with coronary artery disease.

What is the expected CAGR of the global medical nitroglycerin sprays market from 2023 to 2033?

The global medical nitroglycerin sprays market is expected to grow at a CAGR of 3.9% from 2023 to 2033[1][4].

Which regions are expected to contribute significantly to the market's growth?

North America, Europe, and the Asia Pacific region are expected to be significant contributors to the market's growth[1].

What are the major challenges facing the nitroglycerin sprays market?

The market faces challenges such as side effects like migraines and resistance to microvascular angina, which can impact blood pressure[1][4].

How did the COVID-19 pandemic affect the nitroglycerin API market?

The COVID-19 pandemic initially disrupted the supply chain but later led to a surge in demand for nitroglycerin API, particularly in the healthcare sector, resulting in a gradual market recovery[3].

Sources

1. Future Market Insights: Medical Nitroglycerin Sprays Market Share & Forecast to 2033.
2. FDA: 208424Orig1s000 - accessdata.fda.gov.
3. Cognitive Market Research: Nitroglycerin API market.
4. PharmiWeb: Global Medical Nitroglycerin Sprays Market to Grow at 3.9% CAGR.
5. Perrigo: FDA Final Approval For Generic Version Of Nitrolingual Spray.