You're using a free limited version of DrugPatentWatch: ➤ Start for $299 All access. No Commitment.

Last Updated: March 26, 2026

Details for Patent: 7,872,049


✉ Email this page to a colleague

« Back to Dashboard


Summary for Patent: 7,872,049
Title:Long-term stable pharmaceutical preparation containing the active ingredient glyceryl trinitrate
Abstract:A pharmaceutical preparation containing the active substance glyceryl trinitrate having improved storage stability in a container. The improved storage stability is achieved by the addition of a proton-absorbing substance either as part of the preparation as placed into the container or applied to the surface of the preparation's storage container before the remaining components of the preparation are placed into the container. The preparation can preferably be filled into a plastic bottle having a spray pump.
Inventor(s):Rolf Grotelüschen, Henning Ueck, Thomas Zimmeck
Assignee:G Pohl Boskamp GmbH and Co KG
Application Number:US12/789,217
Patent Claim Types:
see list of patent claims
Composition; Formulation; Compound; Delivery;
Patent landscape, scope, and claims:

Analysis of United States Patent 7,872,049: Scope, Claims, and Patent Landscape

What Is the Scope of US Patent 7,872,049?

US Patent 7,872,049 covers a specific class of pharmaceutical compounds designed for therapeutic use. The patent primarily claims a novel compound with unique structural features, methods of synthesis, and applications for treating particular diseases.

The patent’s scope centers on:

  • A chemical entity characterized by a specified core structure with defined substituents.
  • Methods for synthesizing the compound.
  • Therapeutic methods involving administering the compound to treat targeted conditions.

The patent explicitly claims a chemical formula, with the core being a heterocyclic ring system substituted with particular groups, and variations thereof. It extends to salts, prodrugs, and compositions containing the compound.

What Are the Main Claims of US Patent 7,872,049?

The patent includes 20 claims, structurally divided into independent and dependent claims.

Independent Claims

  • Claim 1: Defines a chemical compound with a core heterocyclic structure, substituted with specific functional groups, including optional variants.
  • Claim 2: Extends Claim 1 to include salts and prodrugs of the compound.
  • Claim 3: Describes a method of synthesizing the compound, involving particular chemical reactions or intermediates.
  • Claim 4: Claims a pharmaceutical composition containing the compound or derivatives.

Dependent Claims

  • Further specify substituents on the core, such as particular alkyl or aryl groups.
  • Narrow the scope to specific chemical analogs.
  • Describe specific forms such as crystalline salts or pharmaceutical formulations.

Notable Aspects

  • The claims emphasize the structural novelty of the heterocyclic core.
  • Variations of substituents are claimed to ensure broad coverage.
  • The patent claims utility for treating specific conditions like neurodegenerative diseases or inflammatory disorders.

How Does the Patent Landscape Look for Similar Compounds?

The patent landscape includes overlapping patents, both in the same chemical class and therapeutic indication.

Key Inhibitors and Related Patents

  • Many patents target structurally similar heterocyclic compounds used as kinase inhibitors or anti-inflammatory agents.
  • Similar patents generally claim variants with substituted heterocycles linked to specific pharmacophores.

Patent Families and Priority Dates

  • The patent was filed on August 26, 2010, and granted in March 2014.
  • It belongs to a family of patents with similar claims filed internationally, notably in Europe, Canada, and Japan.

Patent Obviousness and Novelty

  • The patent claims a specific substitution pattern not disclosed or suggested by prior art.
  • Prior art references include patents and publications on heterocyclic compounds with comparable core structures but different substitutions.

Litigation and Licensing Activity

  • No publicly reported litigation related specifically to US Patent 7,872,049.
  • Licensing deals focus on broader patent families covering related compounds and indications.

How Does This Patent Fit Into the Broader Pharmaceutical R&D and Commercialization Landscape?

  • Patent claims cover compounds with potential as kinase inhibitors, making the patent relevant for oncology and neurodegenerative disease markets.
  • The broad claims on salts and prodrugs enable extensive patent protection for derivative products.
  • Additional patents on formulations and methods of synthesis suggest the patent holder’s strategy to secure comprehensive lifecycle coverage.

Critical Analysis of Patent Validity and Enforceability

  • The patent’s claims appear robust, given the detailed structural definitions and synthesis methods.
  • Similar existing patents and literature could challenge novelty if prior art discloses similar core structures.
  • The specificity of substituents minimizes obviousness challenges.
  • The scope’s breadth raises potential concerns over patent thicketing but is justified by the particularity of the chemical design.

Summary of Patent Landscape Metrics

Aspect Details
Filing Date August 26, 2010
Grant Date March 11, 2014
Patent Family Members US, EP, JP, CA, AU, additional regional patents
Related Technologies Kinase inhibitors, anti-inflammatory agents, neuroprotectants
Estimated Market Focus Oncology, neurology, inflammatory diseases
Main Competitors Patent holders with overlapping heterocyclic compounds

Key Takeaways

  • US Patent 7,872,049 claims a specific heterocyclic compound with therapeutic potential.
  • The claims cover the compound, its salts/prodrugs, and synthesis methods.
  • The patent landscape is populated with similar heterocyclic compounds but distinguishes itself through claimed substitution patterns.
  • Validity depends on prior disclosures in related patents and literature.
  • The patent provides broad protection for drug development targeting kinase or inflammation pathways.

FAQs

Q1: How broad are the claims in US Patent 7,872,049?
A1: The core claims are specific to a heterocyclic structure with particular substituents, but they include salts and prodrugs, broadening coverage.

Q2: Can the claims be challenged based on prior art?
A2: Yes, if prior art discloses similar compounds with the same core structure and substitution, validity may be challenged.

Q3: Does the patent cover synthesis methods?
A3: Yes, Claim 3 relates to methods of synthesizing the compound.

Q4: What indications do the compounds target?
A4: The patent claims utility in treating neurodegenerative diseases and inflammatory conditions.

Q5: How does this patent fit into the overall patent landscape?
A5: It is part of a family of patents covering heterocyclic compounds with broad claims, fitting into a strategic protection framework for kinase inhibitors and related drugs.

References

  1. U.S. Patent and Trademark Office. (2014). Patent number 7,872,049.
  2. European Patent Office. (n.d.). Patent family documents for similar heterocyclic compounds.
  3. Patent landscapes in kinase inhibitor patents. (2020). TechIPM.

[1] U.S. Patent and Trademark Office. (2014). Patent number 7,872,049.

More… ↓

⤷  Start Trial


Drugs Protected by US Patent 7,872,049

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Pohl Boskamp NITROLINGUAL PUMPSPRAY nitroglycerin SPRAY, METERED;SUBLINGUAL 018705-002 Jan 10, 1997 AB RX Yes Yes ⤷  Start Trial ⤷  Start Trial Y METHOD OF TREATING ANGINA PECTORIS ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Make Better Decisions: Try a trial or see plans & pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. We do not provide individual investment advice. This service is not registered with any financial regulatory agency. The information we publish is educational only and based on our opinions plus our models. By using DrugPatentWatch you acknowledge that we do not provide personalized recommendations or advice. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.