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Generated: April 23, 2018

DrugPatentWatch Database Preview

CARDENE Drug Profile

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When do Cardene patents expire, and when can generic versions of Cardene launch?

Cardene is a drug marketed by Chiesi Usa Inc and is included in three NDAs. There are four patents protecting this drug and five Paragraph IV challenges.

The generic ingredient in CARDENE is nicardipine hydrochloride. There are eleven drug master file entries for this compound. Ten suppliers are listed for this compound. Additional details are available on the nicardipine hydrochloride profile page.
Drug patent expirations by year for CARDENE
Medical Subject Heading (MeSH) Categories for CARDENE
Synonyms for CARDENE
1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid methyl 2-[methyl(phenylmethyl)amino]ethyl ester hydrochloride
1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)methyl-2-[methyl(phenylmethyl)amino]-3,5-pyridinedicarboxylic acid ethyl ester hydrochloride
1,4-Dihydro-2,6-dimethyl-4-[3-nitrophenyl]methyl-2-[methyl- (phenyl-methl)amino]-3,5- pyridinedicarboxylic acid ethyl ester
1,4-Dihydro-2,6-dimethyl-4-[3-nitrophenyl]methyl-2-[methyl-(phenyl-methl)amino]-3,5-pyridinedicarboxylic acid ethyl ester
2-(benzyl-methyl-amino)ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride
2-(Benzyl(methyl)amino)ethyl methyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)pyridine-3,5-dicarboxylate hydrochloride
2-(benzylmethylamino)ethl methyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate monohydrochloride
2-(Benzylmethylamino)ethyl methyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylatemonohydrochloride
2-(Benzylmethylamino)ethyl methyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate monohydrochloride
2-(N-benzyl-N-methylamino)ethyl methyl 2,6-dimethyl-4-(m-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride
2-[benzyl(methyl)amino]ethyl-methyl-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridin-3,5-dicarboxylathydrochlorid
2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid O3-methyl ester O5-[2-[methyl-(phenylmethyl)amino]ethyl] ester hydrochloride
3-(2-(benzyl(methyl)amino)ethyl) 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride
3-{2-[benzyl(methyl)amino]ethyl} 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride
3,5-pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-methyl 5-[2-[methyl(phenylmethyl)amino]ethyl] ester, hydrochloride (1:1)
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, methyl 2-(methyl(phenylmethyl)amino)ethyl ester, monohydrochloride
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-, 2-(benzylmethylamino)ethyl methyl ester, monohydrochloride
4- ?CHLORO- DIFLUORO- METHOXY) ? PHENYLAMINE
5-O-[2-[benzyl(methyl)amino]ethyl] 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride
5-O-[2-[benzyl(methyl)amino]ethyl] 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate;hydrochloride
527N843
54527-84-3
69441-18-5
A830225
AC1L253M
AC1Q67X4
AIKVCUNQWYTVTO-UHFFFAOYSA-N
AKOS015994734
AN-40518
Angioglebil
ANW-42546
BC201356
BCP9000988
Bionicard
C25H27N3O6.HCl
Cardene In 0.83% Sodium Chloride In Plastic Container
Cardene In 0.86% Sodium Chloride In Plastic Container
Cardene In 4.8% Dextrose In Plastic Container
Cardene In 5.0% Dextrose In Plastic Container
Cardene SR
CAS-54527-84-3
CCG-39033
CCRIS 8508
CHEBI:7551
CHEMBL1200326
CHEMBL3199626
CPD004727071
CS-3684
CTK2F3563
D00617
Dafil
Dagan
DSSTox_CID_26992
DSSTox_GSID_46992
DSSTox_RID_82040
DTXSID9046992
EBD48801
EINECS 259-198-4
EINECS 274-007-4
EU-0100809
FT-0082866
FT-0630671
HMS1569M07
HMS1921H21
HY-12515A
KS-1276
Lincil
Loxen
LP00809
LS-131264
MFCD00057327
MLS000069782
MLS001146898
MLS002153279
MLS002153794
MolPort-003-666-362
N 7510
N0635
NC00578
NCGC00094142-01
NCGC00094142-02
NCGC00094142-03
NCGC00094142-04
NCGC00094142-05
NCGC00256289-01
NCGC00261494-01
NE54503
Nerdipine
Nicardil
Nicardipine (Hydrochloride)
Nicardipine for system suitability, European Pharmacopoeia (EP) Reference Standard
Nicardipine HCl
NICARDIPINE HYDROCHLORIDE
Nicardipine hydrochloride (JP17/USAN)
Nicardipine hydrochloride [USAN:JAN]
Nicardipine hydrochloride, European Pharmacopoeia (EP) Reference Standard
Nicardipine hydrochloride, powder, >=98%
Nicardipine hydrochloride, United States Pharmacopeia (USP) Reference Standard
nicardipine;
Nicardipinehydrochloride
Nicodel
NSC-757855
NSC757855
O3-methyl O5-[2-[methyl-(phenylmethyl)amino]ethyl] 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride
O5-[2-[benzyl(methyl)amino]ethyl] O3-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride
Opera_ID_357
Perdipina
Perdipine
Perpidine
Pharmakon1600-01501135
Prestwick_590
RS-69216
RS-69216-XX-07-0
RS-69216-XX-07-O
s4181
SAM002564254
SAM002643513
SCHEMBL41845
SMR000058487
SPECTRUM1501135
SR-01000075333
SR-01000075333-1
TN-901
Tox21_301832
Tox21_500809
TR-019279
W-105615
YC 93
YC-93
YC-93 hydrochloride

US Patents and Regulatory Information for CARDENE

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Chiesi Usa Inc CARDENE nicardipine hydrochloride CAPSULE;ORAL 019488-001 Dec 21, 1988 DISCN No No ➤ Try a Free Trial ➤ Try a Free Trial ➤ Try a Free Trial
Chiesi Usa Inc CARDENE IN 5.0% DEXTROSE IN PLASTIC CONTAINER nicardipine hydrochloride INJECTABLE;INTRAVENOUS 019734-005 Nov 7, 2008 DISCN Yes No ➤ Try a Free Trial ➤ Try a Free Trial Y ➤ Try a Free Trial
Chiesi Usa Inc CARDENE IN 0.83% SODIUM CHLORIDE IN PLASTIC CONTAINER nicardipine hydrochloride INJECTABLE;INTRAVENOUS 019734-004 Nov 7, 2008 RX Yes Yes ➤ Try a Free Trial ➤ Try a Free Trial Y ➤ Try a Free Trial
Chiesi Usa Inc CARDENE IN 0.83% SODIUM CHLORIDE IN PLASTIC CONTAINER nicardipine hydrochloride INJECTABLE;INTRAVENOUS 019734-004 Nov 7, 2008 RX Yes Yes ➤ Try a Free Trial ➤ Try a Free Trial ➤ Try a Free Trial
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration

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Expired US Patents for CARDENE

Applicant Tradename Generic Name Dosage NDA Approval Date Patent No. Patent Expiration
Chiesi Usa Inc CARDENE nicardipine hydrochloride INJECTABLE;INJECTION 019734-001 Jan 30, 1992 ➤ Try a Free Trial ➤ Try a Free Trial
Chiesi Usa Inc CARDENE nicardipine hydrochloride INJECTABLE;INJECTION 019734-001 Jan 30, 1992 ➤ Try a Free Trial ➤ Try a Free Trial
Chiesi Usa Inc CARDENE nicardipine hydrochloride CAPSULE;ORAL 019488-001 Dec 21, 1988 ➤ Try a Free Trial ➤ Try a Free Trial
Chiesi Usa Inc CARDENE nicardipine hydrochloride INJECTABLE;INJECTION 019734-001 Jan 30, 1992 ➤ Try a Free Trial ➤ Try a Free Trial
Applicant Tradename Generic Name Dosage NDA Approval Date Patent No. Patent Expiration

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Paragraph IV (Patent) Challenges for CARDENE
Drugname Dosage Strength RLD Submissiondate
➤ Subscribe Injection 0.1 mg/mL, 200 mL and0.2mg/mL, 200 mL ➤ Subscribe 2013-06-20
➤ Subscribe Injection 0.1 mg/mL, 200 mL and0.2mg/mL, 200 mL ➤ Subscribe 2013-06-20
➤ Subscribe Injection 0.1 mg/mL, 200 mL and0.2mg/mL, 200 mL ➤ Subscribe 2013-06-20
➤ Subscribe Injection 0.1 mg/mL, 200 mL and0.2mg/mL, 200 mL ➤ Subscribe 2013-06-20
➤ Subscribe Injection 2.5 mg/mL, 10 mL Ampoules ➤ Subscribe 2006-12-27

For more information try a trial or see the plans and pricing

Serving hundreds of leading biopharmaceutical companies globally:

Express Scripts
Farmers Insurance
Citi
Johnson and Johnson
Argus Health
US Department of Justice
Fish and Richardson
Covington
Accenture

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