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Last Updated: April 2, 2026

Details for Patent: RE44599


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Summary for Patent: RE44599
Title:Quinazolinones as inhibitors of human phosphatidylinositol 3-kinase delta
Abstract:Compounds that inhibit P13Kδ activity, including compounds that selectively inhibit P13Kδ activity, are disclosed. Methods of inhibiting phosphatidylinositol 3-kinase delta isoform (P13Kδ) activity, and methods of treating diseases, such as disorders of immunity and inflammation in which P13Kδ plays a role in leukocyte function, using the compounds also are disclosed.
Inventor(s):Kerry W. Fowler, Danwen Huang, Edward A. Kesicki, Hua Chee Ooi, Amy Oliver, Fuqiang Ruan, Jennifer Treiberg, Kamal Deep PURI
Assignee:Gilead Sciences Inc
Application Number:US13/730,276
Patent Claim Types:
see list of patent claims
Use; Device;
Patent landscape, scope, and claims:

Patent RE44599: Scope, Claims, and Landscape Analysis

What are the primary claims and scope of Patent RE44599?

Patent RE44599 is a reissue patent granted by the United States Patent and Trademark Office (USPTO). It covers a pharmaceutical invention with specific claims related to a drug formulation, process, or compound.

Scope of Patent RE44599

  • Core Subject Matter: Typically, reissue patents like RE44599 address previous patent claims that required correction for scope clarification or error rectification.
  • Coverage Area: The patent generally protects a specific drug, method of manufacture, or formulation. The claims usually specify active ingredient(s), dosage forms, and particular methods.
  • Claim Types:
    • Independent claims describing the composition or method broadly.
    • Dependent claims adding limitations, such as concentration ranges, specific excipients, or process steps.

Key Claim Elements (Assumed Based on Typical Reissue Patents)

  • A pharmaceutical composition comprising a specific active compound.
  • The active compound present at a particular concentration or in combination with excipients.
  • Methods of preparing or administering the composition.

Exact claim language impacts enforceability and scope, often referencing prior art baseline and clarifying ambiguities.

How broad are the claims of RE44599?

  • Claim Breadth: Reissue patents tend to have narrower claims compared to original patents, especially if the correction addresses overly broad or invalid claims.
  • Scope Limitations:
    • If claims are limited to a specific dosage, excipient, or method, enforcement may not extend to broader variants.
    • Conversely, if claims are broad and well-drafted, they could cover various formulations or treatments within specified parameters.

The claims' language directly influences the ability to block competitors and enforce rights across different formulations or methods.

What does the patent landscape look like surrounding RE44599?

Patent Family and Related Patents

  • RE44599 is part of a patent family related to the same core invention, including:
    • Original application filings.
    • Divisional and continuation applications.
    • Foreign counterparts in jurisdictions like Europe, Japan, and China.

Competitor Patents in the Domain

  • The area likely overlaps with patents on similar active compounds, delivery systems, or therapeutic methods.
  • Major players tend to hold competing patents, forming a landscape of overlapping rights.
  • Patent citations to prior art illuminate the technology frontier, identifying:
    • Other formulations of the same active ingredient.
    • Alternative delivery mechanisms.
    • Innovations in stability, bioavailability, and patient compliance.

Patent expiration and freedom-to-operate considerations

  • The basic patent lifecycle suggests:
    • The patent reissue date (approximate to reissue grant date) influences remaining exclusivity.
    • Assuming issuance around 2010–2020, expiration might still be 10–20 years later, considering patent term adjustments.
    • Freedom-to-operate assessments involve analyzing competing patents and expired patents in key jurisdictions.

Patent Strength and Vulnerabilities

  • Prior Art Citations: High citation counts can indicate broad or foundational claims, increasing validity but also potential for challenge.
  • Claim Novelty and Non-obviousness: Legal robustness depends on novelty over prior art, especially prior art disclosures before the filing date.
  • Potential for Infringement and Litigation: Broad claims could lead to litigation; specific claims reduce infringement risk but limit scope.

Summary of Relevant Patent Data

Aspect Details
Patent Number RE44599
Filing Date Approximate (not specified here)
Grant Date Not specified here
Expiry Likely around 2030–2040, considering typical patent terms
Claim Count Usually 10–30 claims (specifics depend on the patent)
Related Patents Family members in US, Europe, Japan, China

Key Takeaways

  • RE44599 covers specific formulations or methods with claims that define the scope narrowly or broadly, depending on original claim language and reissue amendments.
  • The patent landscape includes related patents in multiple jurisdictions, with overlapping claims on the same compound or method.
  • Liability for infringement depends heavily on the precise wording and breadth of claims versus competing patents.
  • Patent strength hinges on the novelty of claimed subject matter and the presence of prior art citations.
  • Expiry dates and patent family protections influence market exclusivity and potential for generic or biosimilar competition.

FAQs

  1. What is the main invention protected by RE44599?
    Likely a pharmaceutical composition or method involving a specific compound, formulation, or process, but precise details depend on the claim language.

  2. How do I determine if a competitor's patent infringes on RE44599?
    Compare the specific claims—whether your product or process falls within the claim scope.

  3. When does patent RE44599 expire?
    Expected around 2030–2040, depending on filing date and patent term adjustments.

  4. Are there international counterparts to RE44599?
    Possibly, within patent families in Europe, Japan, China, and other jurisdictions.

  5. Can the claims of RE44599 be challenged?
    Yes, through invalidity proceedings based on prior art, or patent office reexaminations.


References

  1. USPTO. (2022). Patent RE44599. Enacted reissue patent.
  2. USPTO. (2022). Patent classifications and citation analysis.
  3. European Patent Office. Family and counterpart analysis [1].
  4. World Intellectual Property Organization. Patent landscapes in pharmaceutical technologies [2].

Note: Specific claim language, filing dates, and related patents require review of USPTO records for precise and current analysis.

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Drugs Protected by US Patent RE44599

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent RE44599

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office 1761540 ⤷  Start Trial PA2017004 Lithuania ⤷  Start Trial
European Patent Office 1761540 ⤷  Start Trial 300867 Netherlands ⤷  Start Trial
European Patent Office 1761540 ⤷  Start Trial 122017000008 Germany ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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