Last Updated: October 27, 2026

Details for Patent: 9,943,537


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Which drugs does patent 9,943,537 protect, and when does it expire?

Patent 9,943,537 protects LONSURF and is included in one NDA.

This patent has twenty-six patent family members in nineteen countries.

Summary for Patent: 9,943,537
Title:Antitumor agent and antitumor effect enhancer
Abstract:Provided is a novel method for treating a cancer using an FTD/TPI combination drug, which shows remarkably excellent antitumor effect and small adverse effects.An antitumor agent, in which a combination drug containing trifluridine and tipiracil hydrochloride at a molar ratio of 1:0.5 and an anti-VEGF antibody or anti-EGFR antibody are administered in combination.
Inventor(s):Hiroyuki Okabe
Assignee: Taiho Pharmaceutical Co Ltd
Application Number:US14/916,878
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 9,943,537
Patent Claim Types:
see list of patent claims
Use;

Drugs Protected by US Patent 9,943,537

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Taiho Oncology LONSURF tipiracil hydrochloride; trifluridine TABLET;ORAL 207981-001 Sep 22, 2015 AB RX Yes No ⤷  Start Trial ⤷  Start Trial TREATMENT OF METASTATIC COLORECTAL CANCER WITH BEVACIZUMAB IN PATIENTS PREVIOUSLY TREATED WITH FLUOROPYRIMIDINE-, OXALIPLATIN- AND IRINOTECAN-BASED CHEMOTHERAPY, AN ANTI-VEGF BIOLOGICAL THERAPY, AND IF RAS WILD-TYPE, AN ANTI-EGFR THERAPY ⤷  Start Trial
Taiho Oncology LONSURF tipiracil hydrochloride; trifluridine TABLET;ORAL 207981-002 Sep 22, 2015 AB RX Yes Yes ⤷  Start Trial ⤷  Start Trial TREATMENT OF METASTATIC COLORECTAL CANCER WITH BEVACIZUMAB IN PATIENTS PREVIOUSLY TREATED WITH FLUOROPYRIMIDINE-, OXALIPLATIN- AND IRINOTECAN-BASED CHEMOTHERAPY, AN ANTI-VEGF BIOLOGICAL THERAPY, AND IF RAS WILD-TYPE, AN ANTI-EGFR THERAPY ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 9,943,537

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Australia 2014316030 ⤷  Start Trial
Denmark 3042669 ⤷  Start Trial
European Patent Office 3042669 ⤷  Start Trial
European Patent Office 4201424 ⤷  Start Trial
Spain 2946472 ⤷  Start Trial
Finland 3042669 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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