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Serving hundreds of leading biopharmaceutical companies globally:

Cantor Fitzgerald
Boehringer Ingelheim
US Army
Fish and Richardson
Argus Health
QuintilesIMS
Cipla
Harvard Business School
UBS

Generated: April 22, 2018

DrugPatentWatch Database Preview

Details for Patent: 8,642,012

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Summary for Patent: 8,642,012
Title:Methods of treatment using ammonia-scavenging drugs
Abstract: The invention provides a method for determining a dose and schedule and making dose adjustments of PBA prodrugs used to treat nitrogen retention states, or ammonia accumulation disorders, by measuring urinary excretion of phenylacetylglutamine and/or total urinary nitrogen. The invention provides methods to select an appropriate dosage of a PBA prodrug based on the patient's dietary protein intake, or based on previous treatments administered to the patient. The methods are applicable to selecting or modifying a dosing regimen for a subject receiving an orally administered ammonia scavenging drug.
Inventor(s): Scharschmidt; Bruce (South San Francisco, CA)
Assignee: Hyperion Therapeutics, Inc. (South San Francisco, CA)
Application Number:12/350,111
Patent Claim Types:
see list of patent claims
Use;

Drugs Protected by US Patent 8,642,012

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Horizon Theraps Inc RAVICTI glycerol phenylbutyrate LIQUID;ORAL 203284-001 Feb 1, 2013 RX Yes Yes ➤ Sign Up ➤ Sign Up DOSAGE ADJUSTMENT OF A NITROGEN SCAVENGING DRUG IN THE TREATMENT OF A UREA CYCLE DISORDER ➤ Sign Up
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Serving hundreds of leading biopharmaceutical companies globally:

Chinese Patent Office
Accenture
Julphar
Citi
Teva
Deloitte
Harvard Business School
Chubb
QuintilesIMS

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