Generated: December 10, 2017
DrugPatentWatch Database Preview
Details for Patent: 8,642,012
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Which drugs does patent 8,642,012 protect, and when does it expire?
Summary for Patent: 8,642,012
|Title:||Methods of treatment using ammonia-scavenging drugs|
|Abstract:|| The invention provides a method for determining a dose and schedule and making dose adjustments of PBA prodrugs used to treat nitrogen retention states, or ammonia accumulation disorders, by measuring urinary excretion of phenylacetylglutamine and/or total urinary nitrogen. The invention provides methods to select an appropriate dosage of a PBA prodrug based on the patient's dietary protein intake, or based on previous treatments administered to the patient. The methods are applicable to selecting or modifying a dosing regimen for a subject receiving an orally administered ammonia scavenging drug.|
|Inventor(s):|| Scharschmidt; Bruce (South San Francisco, CA) |
|Assignee:|| Hyperion Therapeutics, Inc. (South San Francisco, CA) |
Patent Claim Types:|
see list of patent claims
International Patent Family for Patent: 8,642,012
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