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Last Updated: September 27, 2020

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Details for Patent: 8,460,641

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Summary for Patent: 8,460,641
Title:Microemulsion process and composition
Abstract: An oil-in-water microemulsion or sub-micron emulsion composition for dermal delivery of at least one pharmaceutically active ingredient, comprising: a first part including at least one occlusive agent and one or more lipophilic surfactants dispersed throughout a second part including water and at least one hydrophilic surfactant, and a non-surfactant amphiphilic type compound, pharmaceutically active ingredient, and water. It has been found that if a non-surfactant amphiphilic type compound is added together with the second part as would conventionally be the case, a microemulsion or sub-micron emulsion is not formed, by adding the so called third part, phase assembly occurs at a lower temperature than would be expected and moreover, this phase appears to assist in maintaining the microemulsion or sub-micron emulsion characteristics of the formulation during storage at normal temperatures.
Inventor(s): Larm; Maria Graziella (Rosanna, AU), Harding; Ronald (North Warrandyte, AU), Johnston; Michael (Yarraville, AU), Abram; Albert Zorko (Wantirna, AU), Vijayakumar; Prema (Fremont, CA), Sun; Phoebe (Mountain View, CA)
Assignee: Stiefel Research Australia Pty Ltd (Rowville, AU)
Application Number:11/216,668
Patent Claim Types:
see list of patent claims
Composition; Delivery; Use;

Drugs Protected by US Patent 8,460,641

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Mylan OLUX E clobetasol propionate AEROSOL, FOAM;TOPICAL 022013-001 Jan 12, 2007 AB2 RX Yes Yes   Start Trial   Start Trial Y TREATMENT OF CORTICOSTEROID-RESPONSIVE DERMATOSES   Start Trial
Almirall VERDESO desonide AEROSOL, FOAM;TOPICAL 021978-001 Sep 19, 2006 RX Yes Yes   Start Trial   Start Trial Y TREATMENT OF ATOPIC DERMATITIS   Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 8,460,641

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Argentina 051197   Start Trial
Australia 2005279704   Start Trial
Brazil PI0514806   Start Trial
Canada 2578594   Start Trial
Canada 2756674   Start Trial
China 101048136   Start Trial
European Patent Office 1796636   Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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Serving leading biopharmaceutical companies globally:

Colorcon
Johnson and Johnson
Boehringer Ingelheim
McKesson
Medtronic
Harvard Business School

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