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VERDESO Drug Profile

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When do Verdeso patents expire, and what generic alternatives are available?

Verdeso is a drug marketed by Aqua Pharms and is included in one NDA. There are five patents protecting this drug.

This drug has forty-seven patent family members in twenty countries.

The generic ingredient in VERDESO is desonide. There are thirty drug master file entries for this compound. Eighteen suppliers are listed for this compound. Additional details are available on the desonide profile page.

Summary for VERDESO

International Patents:	47
US Patents:	5
Applicants:	1
NDAs:	1
Suppliers / Packagers:	1
Bulk Api Vendors:	43
Patent Applications:	4,054
Formulation / Manufacturing:	see details
Patent Litigation and PTAB cases:	See patent lawsuits and PTAB cases for VERDESO
DailyMed Link:	VERDESO at DailyMed

Pharmacology for VERDESO

Drug Class	Corticosteroid
Mechanism of Action	Corticosteroid Hormone Receptor Agonists

Medical Subject Heading (MeSH) Categories for VERDESO

Anti-Inflammatory Agents

Synonyms for VERDESO

(11ss,16alpha)-11,21-Dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione

(1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.0;{2,9}.0;{4,8}.0;{13,18}]icosa-14,17-dien-16-one

(4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-5-hydroxy-6b-(hydroxyacetyl)-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one

11beta,16alpha,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone

11beta,21-dihydroxy-16alpha,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione

11beta,21-dihydroxy-16alpha,17-isopropylidenedioxypregna-1,4-diene-3,20-dione

11beta,21-dihydroxy-16alpha,17alpha-isopropylidenedioxypregna-1,4-diene-3,20-dione

16-alpha-Hydroxyprednisole-16,17-acetonide

16?,17-[1-Methylethylidenebis(oxy)]-11?,21-dihydroxypregna-1,4-diene-3,20-dione

16alpha-hydroxyprednisole-16,17-acetonide

16alpha-hydroxyprednisolone-16alpha,17-acetonide

16alpha,17-[1-Methylethylidenebis(oxy)]-11beta,21-dihydroxypregna-1,4-diene-3,20-dione (Desonide)

16alpha,17alpha-isopropylidenedioxyprednisolone

638-94-8

638D948

AB01274712_02

AB01274712-01

AB2000229

Apolar

AS-13892

budesonide acetonide

C-22009

CAS-638-94-8

CC-26356

CCG-221279

CHEBI:204734

CHEMBL1201109

CS-2228

D 2083

D-2083

D02JNM

D03696

D2083

DB01260

desfluorotriamcinolone acetonide

Desilux

Desonate

Desonida

Desonida [INN-Spanish]

DESONIDE

Desonide (USAN/INN)

Desonide [USAN:INN:BAN]

Desonidum

Desonidum [INN-Latin]

DesOwen

Desowen (TN)

DSSTox_CID_26756

DSSTox_GSID_46756

DSSTox_RID_81880

DTXSID7046756

EINECS 211-351-6

Flusemidon

GTPL7066

Hamiltoderm

HY-B0248

J280872D1O

K016

Locapred

Locapred, Topifug, Tridesilon, Desonide

Locapred;Topifug;Tridesilon

MolPort-003-987-087

NCGC00167983-01

NCGC00274065-01

Prednacinolone

Prednisolone-16,17-acetonide, 16-alpha-hydroxy-

Pregna-1,4-diene-3,20-dione, 11,21-dihydroxy-16,17-((1-methylethylidene)bis(oxy))-, (11beta,16alpha)-

Prenacid

Q-101382

Reticus

s1701

SC-17104

SCHEMBL3631

Sterax

Steroderm

TL8004516

Topifug

Tox21_112603

Tox21_112603_1

Tridesilon

Tridesonit

UNII-J280872D1O

Verdeso (TN)

Verdeso Foam (TN)

WBGKWQHBNHJJPZ-LECWWXJVSA-N

ZINC4212851

Zotinar

US Patents and Regulatory Information for VERDESO

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Exclusivity Expiration
Aqua Pharms	VERDESO	desonide	AEROSOL, FOAM;TOPICAL	021978-001	Sep 19, 2006		RX	Yes	Yes			Y
Aqua Pharms	VERDESO	desonide	AEROSOL, FOAM;TOPICAL	021978-001	Sep 19, 2006		RX	Yes	Yes			Y
Aqua Pharms	VERDESO	desonide	AEROSOL, FOAM;TOPICAL	021978-001	Sep 19, 2006		RX	Yes	Yes			Y
Aqua Pharms	VERDESO	desonide	AEROSOL, FOAM;TOPICAL	021978-001	Sep 19, 2006		RX	Yes	Yes			Y

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Non-Orange Book US Patents for VERDESO

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No.	Title	Estimated Patent Expiration
8,263,580	Vitamin formulation
8,449,867	Microemulsion and sub-micron emulsion process and compositions
8,629,128	Vitamin formulation
8,298,515	Vitamin formulation

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International Patents for VERDESO

Country	Document Number	Estimated Expiration
New Zealand	563560
Australia	2006253913
Russian Federation	2381023
European Patent Office	1796636

Supplementary Protection Certificates for VERDESO

Supplementary Protection Certificate	SPC Country	SPC Expiration	SPC Description
C/GB02/033	United Kingdom		PRODUCT NAME: FORMOTEROL (OPTIONALLY IN THE FORM OF THE FREE BASE OR A PHYSIOLOGICALLY ACCEPTABLE SALT THEREOF, OR A SOLVATE OF SUCH FREE BASE OR SALT ESPECIALLY AS FORMOTEROL FUMARATE DIHYDRATE) AND BUDESONIDE; REGISTERED: SE SE16047, 16048 20000825; UK PL17901/0091 20010515; UK PL17901/0092 20010515