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Last Updated: August 1, 2021

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Details for Patent: 8,268,847


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Which drugs does patent 8,268,847 protect, and when does it expire?

Patent 8,268,847 protects OPSUMIT and is included in one NDA.

This patent has thirty-two patent family members in twenty-seven countries.

Summary for Patent: 8,268,847
Title:Therapeutic compositions comprising a specific endothelin receptor antagonist and a PDE5 inhibitor
Abstract: The invention relates to a product containing the compound of formula (I) below ##STR00001## or a pharmaceutically acceptable salt of this compound, in combination with at least one compound having PDE5-inhibitory properties, or a pharmaceutically acceptable salt thereof, for therapeutic use, simultaneously, separately or over a period of time, in the treatment of a disease wherein vasoconstriction is involved.
Inventor(s): Clozel; Martine (Binningen, CH)
Assignee: Actelion Pharmaceuticals, Ltd. (Allschwil, CH)
Application Number:12/439,290
Patent Claim Types:
see list of patent claims
Use; Compound; Composition;

Drugs Protected by US Patent 8,268,847

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Actelion OPSUMIT macitentan TABLET;ORAL 204410-001 Oct 18, 2013 AB RX Yes Yes ⤷  Try it Free ⤷  Try it Free METHOD OF TREATING PULMONARY HYPERTENSION COMPRISING ADMINISTERING MACITENTAN IN COMBINATION WITH A COMPOUND HAVING PHOSPHODIESTERASE-5 INHIBITORY PROPERTIES ⤷  Try it Free
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 8,268,847

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
PCT/IB2006/052999Aug 29, 2006
PCT/IB2006/053857Oct 19, 2006
PCT Information
PCT FiledAugust 28, 2007PCT Application Number:PCT/IB2007/053448
PCT Publication Date:March 06, 2008PCT Publication Number: WO2008/026156

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Serving leading biopharmaceutical companies globally:

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