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Serving leading biopharmaceutical companies globally:

McKinsey
AstraZeneca
US Department of Justice
Julphar
Dow
UBS
Citi
Chinese Patent Office
Express Scripts
Fish and Richardson

Generated: February 24, 2018

DrugPatentWatch Database Preview

Details for Patent: 7,495,103

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Which drugs does patent 7,495,103 protect, and when does it expire?

Patent 7,495,103 protects KALYDECO and ORKAMBI and is included in three NDAs.

This patent has ninety patent family members in twenty-five countries.
Summary for Patent: 7,495,103
Title:Modulators of ATP-binding cassette transporters
Abstract: The present invention relates to modulators of ATP-Binding Cassette ("ABC") transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
Inventor(s): Hadida-Ruah; Sara (La Jolla, CA), Hazelwood; Anna (San Diego, CA), Grootenhuis; Peter (San Diego, CA), Van Goor; Fred (San Diego, CA), Singh; Ashvani (San Diego, CA), Zhou; Jinglan (San Diego, CA), McCartney; Jason (Cardiff-by-the-Sea, CA)
Assignee: Vertex Pharmaceuticals Incorporated (Cambridge, MA)
Application Number:11/165,818
Patent Claim Types:
see list of patent claims
Compound; Composition;

Drugs Protected by US Patent 7,495,103

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Vertex Pharms Inc KALYDECO ivacaftor GRANULE;ORAL 207925-001 Mar 17, 2015 RX Yes No ➤ Try a Free Trial ➤ Try a Free Trial Y Y ➤ Try a Free Trial
Vertex Pharms Inc KALYDECO ivacaftor GRANULE;ORAL 207925-002 Mar 17, 2015 RX Yes Yes ➤ Try a Free Trial ➤ Try a Free Trial Y Y ➤ Try a Free Trial
Vertex Pharms KALYDECO ivacaftor TABLET;ORAL 203188-001 Jan 31, 2012 RX Yes Yes ➤ Try a Free Trial ➤ Try a Free Trial Y Y ➤ Try a Free Trial
Vertex Pharms Inc ORKAMBI ivacaftor; lumacaftor TABLET;ORAL 206038-002 Sep 28, 2016 RX Yes No ➤ Try a Free Trial ➤ Try a Free Trial Y Y ➤ Try a Free Trial
Vertex Pharms Inc ORKAMBI ivacaftor; lumacaftor TABLET;ORAL 206038-001 Jul 2, 2015 RX Yes Yes ➤ Try a Free Trial ➤ Try a Free Trial Y Y ➤ Try a Free Trial
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Non-Orange Book US Patents Family Members for Patent 7,495,103

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
2,014,187,770 ➤ Try a Free Trial
8,354,427 Modulators of ATP-binding cassette transporters ➤ Try a Free Trial
8,829,204 Modulators of ATP-binding cassette transporters ➤ Try a Free Trial
8,614,327 Modulators of ATP-binding cassette transporters ➤ Try a Free Trial
8,741,925 Modulators of ATP-binding cassette transporters ➤ Try a Free Trial
9,090,619 Modulators of ATP-binding cassette transporters ➤ Try a Free Trial
8,802,700 Modulators of ATP-Binding Cassette transporters ➤ Try a Free Trial
8,629,162 Modulators of ATP-binding cassette transporters ➤ Try a Free Trial
8,101,767 Modulators of ATP-binding cassette transporters ➤ Try a Free Trial
8,324,242 Modulators of ATP-binding cassette transporters ➤ Try a Free Trial
Patent No. Title Estimated Patent Expiration

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International Patents Family Members for US Patent 7,495,103

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Australia 2005258320 ➤ Try a Free Trial
Australia 2010249302 ➤ Try a Free Trial
Australia 2010251787 ➤ Try a Free Trial
Australia 2010251789 ➤ Try a Free Trial
Australia 2010327993 ➤ Try a Free Trial
Australia 2013204751 ➤ Try a Free Trial
Brazil PI0511321 ➤ Try a Free Trial
Canada 2571949 ➤ Try a Free Trial
Canada 2783314 ➤ Try a Free Trial
Canada 2810655 ➤ Try a Free Trial
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Fish and Richardson
Harvard Business School
Julphar
UBS
US Army
Express Scripts
Teva
Colorcon
Queensland Health

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

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