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Patent 7,326,708 protects JANUMET XR, JANUMET, JANUVIA, JUVISYNC, and STEGLUJAN, and is included in five NDAs.
Protection for JANUMET XR has been extended six months for pediatric studies, as indicated by the *PED designation in the table below.
This patent has fifty-two patent family members in forty countries.
Summary for Patent: 7,326,708
|Title:||Phosphoric acid salt of a dipeptidyl peptidase-IV inhibitor|
|Abstract:||The dihydrogenphosphate salt of 4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro [1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-- amine is a potent inhibitor of dipeptidyl peptidase-IV and is useful for the prevention and/or treatment of non-insulin dependent diabetes mellitus, also referred to as type 2 diabetes. The invention also relates to a crystalline monohydrate of the dihydrogenphosphate salt as well as a process for its preparation, pharmaceutical compositions containing this novel form and methods of use for the treatment of diabetes, obesity, and high blood pressure.|
|Inventor(s):||Cypes; Stephen Howard (Santa Clara, CA), Chen; Alex Minhua (Metuchen, NJ), Ferlita; Russell R. (Westfield, NJ), Hansen; Karl (Atlantic Highlands, NJ), Lee; Ivan (Piscataway, NJ), Vydra; Vicky K. (Fair Lawn, NJ), Wenslow, Jr.; Robert M. (East Windsor, NJ)|
|Assignee:||Merck & Co., Inc. (Rahway, NJ)|
|Patent Litigation and PTAB cases:||See patent lawsuits and PTAB cases for patent 7,326,708|
Patent Claim Types:|
see list of patent claims
|Compound; Composition; Use; Process;|
|Country||Patent Number||Estimated Expiration||Supplementary Protection Certificate||SPC Country||SPC Expiration|
|Argentina||044705||⤷ Free Forever Trial|
|Argentina||094185||⤷ Free Forever Trial|
|Austria||373003||⤷ Free Forever Trial|
|Australia||2004253889||⤷ Free Forever Trial|
|Brazil||PI0411726||⤷ Free Forever Trial|
|Canada||2529400||⤷ Free Forever Trial|
|China||100430397||⤷ Free Forever Trial|
|>Country||>Patent Number||>Estimated Expiration||>Supplementary Protection Certificate||>SPC Country||>SPC Expiration|