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Details for Patent: 10,383,876

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Which drugs does patent 10,383,876 protect, and when does it expire?

Patent 10,383,876 protects ALIQOPA and is included in one NDA.

This patent has fifty-two patent family members in forty-one countries.

Summary for Patent: 10,383,876

Title:	Substituted 2,3-dihydroimidazo[1,2-c]quinazoline salts
Abstract:	The present invention relates:--to 2-amino-N-[7-methoxy-8-(3-morpholin-4-ylpropoxy)-2,3-dihydroimidazo-[1,2-- c]quinazolin-5-yl]pyrimidine-5-carboxamide dihydrochloride salt of formula (II): or a tautomer, solvate or hydrate thereof;--to methods of preparing said dihydrochloride salt;--to said dihydrochloride salt for the treatment and/or prophylaxis of a disease;--to the use of said dihydrochloride salt for the preparation of a medicament for the treatment and/or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, more particularly for the treatment or prophylaxis of a cancer, particularly lung cancer, in particular non-small cell lung carcinoma, colorectal cancer, melanoma, pancreatic cancer, hepatocyte carcinoma, pancreatic cancer, hepatocyte carcinoma or breast cancer;--to a pharmaceutical composition comprising said dihydrochloride salt; and--to a pharmaceutical combination comprising said dihydrochloride salt in combination with one or more further pharmaceutical agents. ##STR00001##
Inventor(s):	Peters; Jan-Georg (Solingen, DE), Militzer; Hans-Christian (Odenthal, DE), Muller; Hartwig (Velbert, DE)
Assignee:	BAYER INTELLECTUAL PROPERTY GMBH (Monheim, DE)
Application Number:	14/009,599
Patent Claim Types: see list of patent claims	Use; Composition; Formulation; Compound; Delivery;

Drugs Protected by US Patent 10,383,876

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
Bayer Healthcare	ALIQOPA	copanlisib dihydrochloride	POWDER;INTRAVENOUS	209936-001	Sep 14, 2017		RX	Yes	Yes			Y	Y

Foreign Priority and PCT Information for Patent: 10,383,876

Foriegn Application Priority Data
Foreign Country	Foreign Patent Number	Foreign Patent Date
	11161111	Apr 5, 2011

PCT Information
PCT Filed	March 29, 2012	PCT Application Number:	PCT/EP2012/055600
PCT Publication Date:	October 11, 2012	PCT Publication Number:	WO2012/136553

International Family Members for US Patent 10,383,876

Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
African Regional IP Organization (ARIPO)	3709
Argentina	085718
Australia	2012238891