Details for Patent: 10,239,867

Which drugs does patent 10,239,867 protect, and when does it expire?

Patent 10,239,867 protects TRIKAFTA (COPACKAGED), ALYFTREK, and SYMDEKO (COPACKAGED), and is included in four NDAs.

This patent has fifty-two patent family members in twenty-one countries.

Summary for Patent: 10,239,867

Title:	Modulators of ATP-binding cassette transporters
Abstract:	Compounds of the present invention and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette ("ABC") transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator ("CFTR"). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.
Inventor(s):	Hadida Ruah; Sara S. (La Jolla, CA), Grootenhuis; Peter D. J. (San Diego, CA), Van Goor; Fredrick (San Diego, CA), Zhou; Jinglan (San Diego, CA), Bear; Brian (Oceanside, CA), Miller; Mark T. (San Diego, CA), McCartney; Jason (Cardiff by the Sea, CA), Numa; Mehdi Michel Jamel (San Diego, CA), Yang; Xiaoqing (San Diego, CA)
Assignee:	Vertex Pharmaceuticals Incorporated (Boston, MA)
Application Number:	15/659,926
Patent Claim Types: see list of patent claims	Use; Composition; Compound;

Analyzing the Scope and Claims of United States Patent 10,239,867

To conduct a detailed analysis of the scope and claims of a specific patent, such as United States Patent 10,239,867, it is crucial to follow a systematic approach. Here’s a comprehensive guide to help you navigate this process.

Understanding the Patent Document

Locating the Patent Document

To start, you need to locate the patent document. This can be done using the USPTO's Patent Public Search tool or other databases like Google Patents or the USPTO's main website[1].

Reading the Patent Abstract and Summary

The abstract and summary sections provide a brief overview of the invention. This helps in understanding the core idea and the main claims of the patent.

Detailed Description of the Invention

The detailed description section elaborates on the invention, including its components, how it works, and any specific embodiments. This section is crucial for understanding the scope of the invention.

Analyzing Patent Claims

Identifying Independent and Dependent Claims

Patent claims are the legal definitions of the invention. Independent claims stand alone and define the invention broadly, while dependent claims build upon the independent claims and provide more specific details. Understanding the relationship between these claims is vital for determining the patent's scope[3].

Claim Construction

Claim construction involves interpreting the language of the claims to determine their meaning and scope. This process can be complex and often requires legal expertise.

Claim Scope and Breadth

The scope and breadth of the claims determine what is protected by the patent. Broader claims may cover a wider range of variations, while narrower claims may be more specific but less encompassing.

Examining Prior Art and References

Prior Art Cited in the Patent

The patent document often includes a list of prior art references cited by the examiner during the patent examination process. These references can help in understanding the state of the art at the time of the invention and how the current patent differs from existing technologies[4].

Common Citation Document (CCD)

For patents that are part of an international patent family, the Common Citation Document (CCD) can provide a consolidated view of prior art cited by multiple patent offices. This helps in assessing the global patent landscape related to the invention[1].

Patent Landscape Analysis

Patent Family and Global Dossier

Analyzing the patent family through tools like the Global Dossier can provide insights into related applications filed in other jurisdictions. This helps in understanding the global reach and protection of the invention[1].

Competitor Patents and Market Analysis

Identifying similar patents held by competitors can help in understanding the competitive landscape. This involves searching patent databases using relevant keywords, classifications, and other search strategies.

Legal and Regulatory Considerations

Patent Office Actions and Examination History

The Patent Examination Data System (PEDS) and other tools can provide access to the examination history of the patent, including office actions and responses. This can offer insights into any challenges faced during the patent application process and how they were addressed[1].

Patent Validity and Enforcement

Understanding the legal status of the patent, including any challenges or litigation, is crucial for assessing its validity and enforceability.

Tools and Resources for Analysis

USPTO Patent Public Search

This tool provides enhanced access to prior art and allows for detailed searches of patent documents, including full-text searches and advanced filtering options[1].

Patent and Trademark Resource Centers (PTRCs)

Local PTRCs offer training and resources for conducting patent searches and can be invaluable for those new to patent research[1].

International Patent Databases

Databases from other international intellectual property offices, such as the European Patent Office (EPO) and the World Intellectual Property Organization (WIPO), can provide a broader view of the global patent landscape[1].

Key Takeaways

• Detailed Reading: Thoroughly read the patent document, focusing on the abstract, summary, detailed description, and claims.
• Claim Analysis: Understand the independent and dependent claims and their relationships.
• Prior Art: Review the prior art cited in the patent and use tools like the CCD for a comprehensive view.
• Global Landscape: Analyze the patent family and global dossier to understand the international scope.
• Legal Considerations: Examine office actions, examination history, and any legal challenges to the patent.
• Tools and Resources: Utilize the USPTO Patent Public Search, PTRCs, and international patent databases for a thorough analysis.

FAQs

Q: How do I locate a specific patent document?

A: You can use the USPTO's Patent Public Search tool or other databases like Google Patents to locate a specific patent document by its patent number.

Q: What is the difference between independent and dependent claims?

A: Independent claims stand alone and define the invention broadly, while dependent claims build upon the independent claims and provide more specific details.

Q: How can I determine the scope of a patent claim?

A: Claim construction involves interpreting the language of the claims to determine their meaning and scope. This often requires legal expertise.

Q: What is the Common Citation Document (CCD)?

A: The CCD consolidates prior art cited by multiple patent offices for a patent family, providing a single point of access to citation data.

Q: Where can I find training and resources for conducting patent searches?

A: Local Patent and Trademark Resource Centers (PTRCs) offer training and resources for conducting patent searches.

Sources

1. USPTO - Search for Patents: https://www.uspto.gov/patents/search
2. U.S. Patent and Trademark Office (USPTO) | USAGov: https://www.usa.gov/agencies/u-s-patent-and-trademark-office
3. Patent Claims Research Dataset - USPTO: https://www.uspto.gov/ip-policy/economic-research/research-datasets/patent-claims-research-dataset
4. United States Patent - googleapis.com: https://patentimages.storage.googleapis.com/0b/09/83/6ac173df846860/US10987348.pdf

Drugs Protected by US Patent 10,239,867

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
Vertex Pharms Inc	TRIKAFTA (COPACKAGED)	elexacaftor, ivacaftor, tezacaftor; ivacaftor	GRANULES;ORAL	217660-001	Apr 26, 2023		RX	Yes	No			Y	Y		TREATMENT OF CYSTIC FIBROSIS IN PATIENTS AGED 2 TO
Vertex Pharms Inc	TRIKAFTA (COPACKAGED)	elexacaftor, ivacaftor, tezacaftor; ivacaftor	GRANULES;ORAL	217660-002	Apr 26, 2023		RX	Yes	Yes			Y	Y		TREATMENT OF CYSTIC FIBROSIS IN PATIENTS AGED 2 TO
Vertex Pharms Inc	ALYFTREK	deutivacaftor; tezacaftor; vanzacaftor calcium	TABLET;ORAL	218730-001	Dec 20, 2024		RX	Yes	No			Y	Y		TREATMENT OF CYSTIC FIBROSIS IN PATIENTS AGED 6 YEARS AND OLDER WHO HAVE AT LEAST ONE F508DEL MUTATION OR ANOTHER RESPONSIVE MUTATION IN THE CFTR GENE WITH AN EFFECTIVE AMOUNT OF VANZACAFTOR, TEZACAFTOR, AND DEUTIVACAFTOR
Vertex Pharms Inc	ALYFTREK	deutivacaftor; tezacaftor; vanzacaftor calcium	TABLET;ORAL	218730-002	Dec 20, 2024		RX	Yes	Yes			Y	Y		TREATMENT OF CYSTIC FIBROSIS IN PATIENTS AGED 6 YEARS AND OLDER WHO HAVE AT LEAST ONE F508DEL MUTATION OR ANOTHER RESPONSIVE MUTATION IN THE CFTR GENE WITH AN EFFECTIVE AMOUNT OF VANZACAFTOR, TEZACAFTOR, AND DEUTIVACAFTOR

International Family Members for US Patent 10,239,867

Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
Australia	2007235260
Brazil	PI0710965
Canada	2648719
Canada	2869945