Last Updated: September 24, 2026

Details for Patent: 10,208,307


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Which drugs does patent 10,208,307 protect, and when does it expire?

Patent 10,208,307 protects AMVUTTRA and is included in one NDA.

This patent has sixty-three patent family members in thirty-seven countries.

Summary for Patent: 10,208,307
Title:Transthyretin (TTR) iRNA compositions and methods of use thereof for treating or preventing TTR-associated diseases
Abstract:The present invention provides iRNA agents, e.g., double stranded iRNA agents, that target the transthyretin (TTR) gene and methods of using such iRNA agents for treating or preventing TTR-associated diseases.
Inventor(s):Tracy Zimmermann, Amy Chan, Vasant Jadhav, Martin Maier, Kallanthottathil G. Rajeev
Assignee: Alnylam Pharmaceuticals Inc
Application Number:US15/221,651
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 10,208,307
Patent Claim Types:
see list of patent claims
Use; Composition; Formulation; Dosage form;

Drugs Protected by US Patent 10,208,307

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Alnylam Pharms Inc AMVUTTRA vutrisiran sodium SOLUTION;SUBCUTANEOUS 215515-001 Jun 13, 2022 RX Yes Yes ⤷  Start Trial ⤷  Start Trial Y Y AMVUTTRA IS INDICATED FOR THE TREATMENT OF THE POLYNEUROPATHY OF HEREDITARY TRANSTHYRETIN-MEDIATED AMYLOIDOSIS IN ADULTS ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 10,208,307

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office 3329002 ⤷  Start Trial 301216 Netherlands ⤷  Start Trial
European Patent Office 3329002 ⤷  Start Trial PA2023505 Lithuania ⤷  Start Trial
European Patent Office 3329002 ⤷  Start Trial 7/2023 Austria ⤷  Start Trial
European Patent Office 3329002 ⤷  Start Trial 2023C/507 Belgium ⤷  Start Trial
European Patent Office 3329002 ⤷  Start Trial LUC00297 Luxembourg ⤷  Start Trial
European Patent Office 3329002 ⤷  Start Trial CA 2023 00008 Denmark ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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