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Generated: May 25, 2018

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Desmopressin acetate - Generic Drug Details

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What are the generic drug sources for desmopressin acetate and what is the scope of desmopressin acetate patent protection?

Desmopressin acetate
is the generic ingredient in ten branded drugs marketed by Ferring Pharms Inc, Bedford, Hospira, Sagent Pharms, Sun Pharm Inds Ltd, Teva Pharms Usa, Ferring, Sun Pharm Inds, Bausch And Lomb, Apotex Inc, Sun Pharma Global, Zydus Pharms Usa Inc, Avadel Speclt, Actavis Labs Fl Inc, Glenmark Pharms Ltd, Heritage Pharma, Impax Labs Inc, and Mylan Pharms Inc, and is included in twenty-six NDAs. There are four patents protecting this compound. Additional information is available in the individual branded drug profile pages.

Desmopressin acetate has eighty-nine patent family members in thirty countries.

There are twenty drug master file entries for desmopressin acetate. Twenty-seven suppliers are listed for this compound.
Synonyms for desmopressin acetate
(2S)-N-[(2R)-1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-
(Deamino-Cys1,D-Arg8)-Vasopressin
(DEAMINO-CYS1,D-ARG8)-VASOPRESSIN ACETATE
(DEAMINO-CYS1,D-ARG8)-VASOPRESSIN ACETATE SALT
(S)-1-((4R,7S,10S,13S,16S)-7-(2-Amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)-N-((R)-1-((2-amino-2-oxoethyl)amino)-5-g
(S)-1-((4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)-N-((R)-1-(2-amino-2-oxoethylamino)-5-gua
1-(3-Mercaptopropanoic Acid)-8-d-arginine Vasopressin Monoacetate
1-(3-mercaptopropanoic acid)-8-D-arginine vasopression monoacetate trihydrate
1-(3-Mercaptopropanoic acid)-8-D-argininevasopressin monoacetate (salt), trihydrate
1-(3-Mercaptopropionic acid)-8-D-arginine vasopression monoacetate
1-(3-mercaptopropionic acid)-8-D-arginine vasopression monoacetate trihydrate
1-(3-mercaptopropionic acid)-8-D-arginine-vasopressin
1-(3-Mercaptopropionic acid)-8-D-arginine-vasopressin diacetate
1-(3-Mercaptopropionic acid)-8-D-arginine-vasopressin monoacetate (salt) trihydrate
1-(7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)-N-(1-((2-amino-2-o
1-{[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-prolyl-D-arginylglycinamide
1-{[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-prolyl-D-arginylglycinamide acetate--wa
1-{[7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}prolyl-n5-(diaminomethylidene)ornithylglycinamide acetate(1:1)
1-{[7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}prolyl-n5-(diaminomethylidene)ornithylglycinamide acetate(1:2)
1-Deamino-8-D-arginine vasopressin
1-deamino-8-D-arginine vasopressin acetate trihydrate
1-Deamino-8-D-arginine-vasopressin diacetate
1-Desamino-8-D-arginine vasopressin
1-desamino-8-D-arginine vasopressin acetate trihydrate
16679-58-6
16679-58-6 (Parent)
16789-98-3
1K12647SFC
2-({1-[13-BENZYL-10-(2-CARBAMOYLETHYL)-7-(CARBAMOYLMETHYL)-16-[(4-HYDROXYPHENYL)METHYL]-6,9,12,15,18-PENTAOXO-1,2-DITHIA-5,8,11,14,17-PENTAAZACYCLOICOSANE-4-CARBONYL]PYRROLIDIN-2-YL}FORMAMIDO)-N-(CARBAMOYLMETHYL)-5-[(DIAMINOM
242K8LE2BC
3-MERCAPTOPROPIONYL-TYR-PHE-GLN-ASN-CYS-PRO-D-ARG-GLY-NH2 (DISULFIDE BOND) ACETATE SALT
3-MERCAPTOPROPIONYL-TYR-PHE-GLN-ASN-CYS-PRO-D-ARG-GLY-NH2 ACETATE SALT (DISULFIDE BOND)
3576AH
3577AH
357D862
62288-83-9
62288-83-9 (monoacetate)
62357-86-2
62357-86-2 (monoacetate trihydrate)
679D586
789D983
8-d-Arginine-1-(3-mercapto-propanoic Acid)vasopresin Monoacetate
A810919
A833738
ABP000576
AC1L21V2
AC1L21V5
AC1L506T
AC1NSJXN
AC1Q5SZE
AC1Q5T0K
acetic acid; 1-[7-(2-amino-2-oxo-ethyl)-10-(3-amino-3-oxo-propyl)-13-benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[1-[(2-amino-2-oxo-ethyl)carbamoyl]-4-gu
acetic acid; N-[1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-1-[[7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-13-(phenylmethyl)-1,2-dithia-5
acetic acid; N-[1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-1-[7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,
Adiuretin
ADIURETIN ACETATE
Adiuretin SD
ADIURETIN SD ACETATE
AKOS015994650
AKOS025311518
AKOS030485983
AKOS030573306
AM000474
AM000514
AM010547
AN-7545
BDBM50205308
C46H64N14O12S2
C46H64N14O12S2.C2H4O2
C46H64N14O12S2.C2H4O2.3H2O
CAS-62288-83-9
CD-644
CHEBI:4450
CHEBI:59728
CHEMBL1200556
CHEMBL1429
CHEMBL2138698
CHEMBL2358584
CONCENTRAID
CS-0952
CTK8F9082
D02235
DDAVP
DDAVP (NEEDS NO REFRIGERATION)
DDAVP (TN)
DDAVP ACETATE
DDAVP ACETATE SALT
DDAVP Nasal Spray
DDAVP Rhinal Tube
Deamino Arginine Vasopressin
DEAMINO ARGININE VASOPRESSIN ACETATE
Deamino-8-D-arginine, l-, vasopressin
Demopressin acetate
Desamino-8-D-arginine vasopressin, l-
Desmopresina
Desmopresina [INN-Spanish]
DESMOPRESINA ACETATE
DESMOPRESSIN
Desmopressin (Acetate)
Desmopressin [INN:BAN]
Desmopressin acetate (needs NO refrigeration)
Desmopressin acetate (USAN)
Desmopressin acetate [USAN:JAN]
Desmopressin acetate [USAN:USP:JAN]
Desmopressin acetate anhydrous
Desmopressin acetate hydrate
Desmopressin acetate hydrate (JAN)
DESMOPRESSIN ACETATE PRESERVATIVE FREE
DESMOPRESSIN ACETATE SALT
Desmopressin acetate trihydrate
Desmopressin Acetate(1:2)
Desmopressin Acetate(STIMATE, DDAVP)/
Desmopressin diacetate
Desmopressin diacetate anhydrous
Desmopressin monoacetate
Desmopressine
Desmopressine [INN-French]
DESMOPRESSINE ACETATE
Desmopressinum
Desmopressinum [INN-Latin]
DESMOPRESSINUM ACETATE
Desmospray
DSSTox_CID_26864
DSSTox_GSID_46864
DSSTox_RID_81971
DTXSID4046864
EINECS 240-726-7
ENR1LLB0FP
FT-0603106
FT-0624526
FT-0653786
FT-0688024
H661
HS-2010
HY-17370
KS-00002WUQ
KW-8008
LS-161413
Minirin
MINIRIN ACETATE
Minirine
minirinmelt
Minirinmelt (TN)
MLSVJHOYXJGGTR-IFHOVBQLSA-N
MolPort-006-069-425
N-[1-[(2-azanyl-2-oxidanylidene-ethyl)amino]-5-[bis(azanyl)methylideneamino]-1-oxidanylidene-pentan-2-yl]-1-[[7-(2-azanyl-2-oxidanylidene-ethyl)-10-(3-azanyl-3-oxidanylidene-propyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-p
NCGC00181133-01
NCGC00181133-02
NCGC00263573-01
NFLWUMRGJYTJIN-PNIOQBSNSA-N
Octim
Octostim
Presinex
SC-18848
SCH2CH2CO-TYR-PHE-GLN-ASN-CYS-PRO-D-ARG-GLY-NH2 ACETATE
SCHEMBL1172203
SCHEMBL14027607
SCHEMBL204511
Stimate
Stimate (TN)
STIMATE ACETATE
Stimate injection
Stimate Nasal Spray
Tox21_112740
Tox21_112740_1
UNII-1K12647SFC
UNII-242K8LE2BC
UNII-ENR1LLB0FP
UNII-XB13HYU18U
VA10693
Vasopressin, 1-(3-mercaptopropanoic acid)-8-D-arginine-
Vasopressin, 1-(3-mercaptopropanoic acid)-8-D-arginine-, diacetate (salt)
Vasopressin, 1-(3-mercaptopropanoic acid)-8-D-arginine-, monoacetate (salt)
Vasopressin, 1-(3-mercaptopropanoic acid)-8-D-arginine-, monoacetate (salt), trihydrate
W-5074
XB13HYU18U
xoethyl)amino)-5-((diaminomethylene)amino)-1-oxopentan-2-yl)pyrrolidine-2-carboxamide diacetate

US Patents and Regulatory Information for desmopressin acetate

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Ferring Pharms Inc DDAVP desmopressin acetate SPRAY, METERED;NASAL 017922-002 Feb 6, 1989 DISCN Yes No ➤ Try a Free Trial ➤ Try a Free Trial ➤ Try a Free Trial
Sagent Pharms DESMOPRESSIN ACETATE desmopressin acetate INJECTABLE;INJECTION 204695-001 Aug 22, 2017 AP RX No No ➤ Try a Free Trial ➤ Try a Free Trial ➤ Try a Free Trial
Ferring Pharms Inc STIMATE desmopressin acetate SPRAY, METERED;NASAL 020355-001 Mar 7, 1994 DISCN No No ➤ Try a Free Trial ➤ Try a Free Trial ➤ Try a Free Trial
Ferring DESMOPRESSIN ACETATE desmopressin acetate TABLET;ORAL 021795-002 May 8, 2008 DISCN No No ➤ Try a Free Trial ➤ Try a Free Trial ➤ Try a Free Trial
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration

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Expired US Patents for desmopressin acetate

Applicant Tradename Generic Name Dosage NDA Approval Date Patent No. Patent Expiration
Ferring Pharms Inc DDAVP desmopressin acetate TABLET;ORAL 019955-002 Sep 6, 1995 ➤ Try a Free Trial ➤ Try a Free Trial
Ferring Pharms Inc DDAVP desmopressin acetate SOLUTION;NASAL 017922-001 Approved Prior to Jan 1, 1982 ➤ Try a Free Trial ➤ Try a Free Trial
Ferring Pharms Inc DDAVP desmopressin acetate INJECTABLE;INJECTION 018938-001 Mar 30, 1984 ➤ Try a Free Trial ➤ Try a Free Trial
Ferring Pharms Inc DDAVP desmopressin acetate INJECTABLE;INJECTION 018938-001 Mar 30, 1984 ➤ Try a Free Trial ➤ Try a Free Trial
Applicant Tradename Generic Name Dosage NDA Approval Date Patent No. Patent Expiration

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Non-Orange Book US Patents for desmopressin acetate

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
8,143,225 Pharmaceutical compositions including low dosages of desmopressin ➤ Try a Free Trial
7,560,429 Orodispersible dosage forms of desmopressin acetate ➤ Try a Free Trial
9,504,647 Pharmaceutical formulations of desmopressin ➤ Try a Free Trial
9,220,747 Methods using desmopressin acetate in orodispersible form ➤ Try a Free Trial
Patent No. Title Estimated Patent Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Julphar
Covington
McKinsey
Healthtrust
US Army
Chinese Patent Office
Baxter
Cipla
Fish and Richardson

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