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Generated: December 12, 2018

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DIHYDROERGOTAMINE MESYLATE - Generic Drug Details

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What are the generic sources for dihydroergotamine mesylate and what is the scope of dihydroergotamine mesylate freedom to operate?

Dihydroergotamine mesylate is the generic ingredient in four branded drugs marketed by Valeant, Hikma Pharms, Paddock Llc, Sagent Pharms, West-ward Pharms Int, and Novartis, and is included in seven NDAs. Additional information is available in the individual branded drug profile pages.

There are six drug master file entries for dihydroergotamine mesylate. Seven suppliers are listed for this compound.

Pharmacology for DIHYDROERGOTAMINE MESYLATE
Medical Subject Heading (MeSH) Categories for DIHYDROERGOTAMINE MESYLATE
Synonyms for DIHYDROERGOTAMINE MESYLATE
(10alphaH)-5'alpha-benzyl-12'-hydroxy-2'-methyl-3',6',18-trioxo-9,10-dihydroergotaman mesylate
(10alphaH)-5'alpha-benzyl-12'-hydroxy-2'-methyl-3',6',18-trioxo-9,10-dihydroergotaman methanesulfonate
(2R,4R,7R)-N-[(1S,2S,4R,7S)-7-BENZYL-2-HYDROXY-4-METHYL-5,8-DIOXO-3-OXA-6,9-DIAZATRICYCLO[7.3.0.0(2),?]DODECAN-4-YL]-6-METHYL-6,11-DIAZATETRACYCLO[7.6.1.0(2),?.0(1)(2),(1)?]HEXADECA-1(16),9,12,14-TETRAENE-4-CARBOXAMIDE; METHA
(4R,7R)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.0^{2,6}]dodecan-4-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(15),9,12(16),13-tetraene-4-carboxamide; metha
(4R,7R)-N-[(1S,2S,4R,7S)-7-BENZYL-2-HYDROXY-4-METHYL-5,8-DIOXO-3-OXA-6,9-DIAZATRICYCLO[7.3.0.0(2),?]DODECAN-4-YL]-6-METHYL-6,11-DIAZATETRACYCLO[7.6.1.0(2),?.0(1)(2),(1)?]HEXADECA-1(16),9,12,14-TETRAENE-4-CARBOXAMIDE; METHANES
(6aR,9R,10aR)-N-[(2R,5S,10aS,10bS)-5-Benzyl-10b-hydroxy-2-methyl-3,6-dioxooctahydro-8H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl]-7-methyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxa
(6aR,9R)-N-((2R,5S,10aS,10bS)-5-benzyl-10b-hydroxy-2-methyl-3,6-dioxooctahydro-8H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl)-7-methyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxamide methanesulfonate
11032-41-0
511-12-6 (Parent)
6190-39-2
81AXN7R2QT
9,10-Dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)ergotaman-3',6',18-trione mesylate
9,10-Dihydroergotamine mesylate
9,10-dihydroergotamine methanesulfonate
910882-41-6
AC1L2FO7
AC1LAOVT
AC1Q6WD6
ADYPXRFPBQGGAH-UMYZUSPBSA-N
AKOS024282478
AN-21195
ANW-42737
C33H37N5O5.CH4O3S
CCG-39548
CHEBI:59756
CHEMBL1200517
CHEMBL1396675
CS-2903
CTK8B3562
D 2763
D.H.E. 45
D02211
D0SP3D
D2633
DETMS
DHE-45
Dihydergot
Dihydroergotamine (mesylate)
Dihydroergotamine for peak identification, European Pharmacopoeia (EP) Reference Standard
Dihydroergotamine mesilate
Dihydroergotamine mesilate (JP17)
Dihydroergotamine mesilate, European Pharmacopoeia (EP) Reference Standard
Dihydroergotamine mesylate (USP)
Dihydroergotamine mesylate [USAN:USP]
Dihydroergotamine mesylate [USAN]
Dihydroergotamine mesylate, United States Pharmacopeia (USP) Reference Standard
Dihydroergotamine methanesulfonate
Dihydroergotamine methanesulfonate salt
Dihydroergotamine methanesulfonate salt, powder
Dihydroergotamine monomethanesulfonate
DIHYDROERGOTAMINE; METHANESULFONIC ACID
Dihydroergotoxin
DIHYDROERGOTOXINE
Dihytamine
DR003475
DR003476
EINECS 228-235-6
Ergoloid dihydroergotoxine
Ergoloid Mesylates (dihydroergotoxine)
Ergotaman-3',6',18-trione, 9,10-dihydro-12'-hydroxy- 2'-methyl-5'-(phenylmethyl)-, (5'?,10?)-, monomethanesulfonate (salt)
Ergotamine, 9,10-dihydro-, monomethanesulfonate (salt)
Ergotamine, dihydro, methanesulfonate (salt)
Ergotoman-3',6',18-trione,9,10-dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)-, (5'alpha)-, monomethanesulfonate (salt)
EU-0100357
HMS1920G16
HMS2094K05
HMS2231H03
HMS3261G15
HMS3266C22
HMS3369K10
HMS501N14
HY-B0670A
I14-101170
LP00357
LS-64558
MFCD00058615
mide methanesulfonate
MLS002153175
MLS002207048
MolPort-003-666-163
MT 300
N-{7-BENZYL-2-HYDROXY-4-METHYL-5,8-DIOXO-3-OXA-6,9-DIAZATRICYCLO[7.3.0.0(2),?]DODECAN-4-YL}-6-METHYL-6,11-DIAZATETRACYCLO[7.6.1.0(2),?.0(1)(2),(1)?]HEXADECA-1(16),9,12,14-TETRAENE-4-CARBOXAMIDE; METHANESULFONIC ACID
NCGC00261042-01
Neomigran
NSC-759848
NSC759848
Pharmakon1600-01500248
PL001844
PL041420
PL057923
Prestwick_746
rboxamide methanesulfonate(salt)
SCHEMBL40843
SCHEMBL40844
SMR001230668
SPECTRUM1500248
SR-01000075382
SR-01000075382-1
ST056346
Tox21_500357
TR-021291
TRA0034972
UNII-81AXN7R2QT
Z1544404034

US Patents and Regulatory Information for DIHYDROERGOTAMINE MESYLATE

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Valeant MIGRANAL dihydroergotamine mesylate SPRAY, METERED;NASAL 020148-001 Dec 8, 1997 RX Yes Yes ➤ Sign Up ➤ Sign Up ➤ Sign Up
Hikma Pharms DIHYDROERGOTAMINE MESYLATE dihydroergotamine mesylate INJECTABLE;INJECTION 206621-001 Sep 15, 2017 AP RX No No ➤ Sign Up ➤ Sign Up ➤ Sign Up
Paddock Llc DIHYDROERGOTAMINE MESYLATE dihydroergotamine mesylate INJECTABLE;INJECTION 040475-001 Apr 28, 2003 AP RX No No ➤ Sign Up ➤ Sign Up ➤ Sign Up
Valeant D.H.E. 45 dihydroergotamine mesylate INJECTABLE;INJECTION 005929-001 Approved Prior to Jan 1, 1982 AP RX Yes Yes ➤ Sign Up ➤ Sign Up ➤ Sign Up
Sagent Pharms DIHYDROERGOTAMINE MESYLATE dihydroergotamine mesylate INJECTABLE;INJECTION 207264-001 Jul 11, 2018 AP RX No No ➤ Sign Up ➤ Sign Up ➤ Sign Up
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration

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Expired US Patents for DIHYDROERGOTAMINE MESYLATE

Applicant Tradename Generic Name Dosage NDA Approval Date Patent No. Patent Expiration
Valeant MIGRANAL dihydroergotamine mesylate SPRAY, METERED;NASAL 020148-001 Dec 8, 1997 ➤ Sign Up ➤ Sign Up
Valeant MIGRANAL dihydroergotamine mesylate SPRAY, METERED;NASAL 020148-001 Dec 8, 1997 ➤ Sign Up ➤ Sign Up
Valeant MIGRANAL dihydroergotamine mesylate SPRAY, METERED;NASAL 020148-001 Dec 8, 1997 ➤ Sign Up ➤ Sign Up
Applicant Tradename Generic Name Dosage NDA Approval Date Patent No. Patent Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Cipla
Deloitte
Federal Trade Commission
Boehringer Ingelheim
Johnson and Johnson
Accenture
US Army
Chubb
Dow

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