You’re using a public version of DrugPatentWatch with 5 free searches available | Register to unlock more free searches. CREATE FREE ACCOUNT

Last Updated: April 26, 2024

Patent: 10,058,630

✉ Email this page to a colleague

« Back to Dashboard

Summary for Patent: 10,058,630

Title:	Methods for inhibiting stenosis, obstruction, or calcification of a stented heart valve or bioprosthesis
Abstract:	Methods for inhibiting stenosis, obstruction and/or calcification of a heart valve following implantation in a vessel having a wall are disclosed. In one aspect the method includes providing a bioprosthetic heart valve mounted on an elastical stent; treating the bioprosthetic heart valve with a tissue fixative; coating the stent and the bioprosthetic valve with a coating composition including one or more therapeutic agents; implanting the bioprosthetic valve into the vessel in a diseased natural valve site; eluting the coating composition from the bioprosthetic valve; and inhibiting stenosis, obstruction and/or calcification of the bioprosthetic heart valve by preventing the attachment of stem cells to the bioprosthetic heart valve, the stem cells circulating external and proximate to the bioprosthetic heart valve by activating nitric oxide production (i) in the circulating stem cells, (ii) in an endothelial cell lining covering the bioprosthetic heart valve tissue, (iii) or both.
Inventor(s):	Rajamannan; Nalini M. (Chicago, IL)
Assignee:	CONCIEVALVE, LLC (Minneapolis, MN)
Application Number:	15/601,236
Patent Claims:	see list of patent claims

Details for Patent 10,058,630

Glossary

Subscribe to access the full database, or Try a Trial
Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Jubilant Hollisterstier Llc	N/A	positive skin test control-histamine	Injection	103891	03/13/1924	⤷ Try a Trial	2032-10-22
Amgen, Inc.	PROLIA	denosumab	Injection	125320	06/01/2010	⤷ Try a Trial	2032-10-22
Amgen, Inc.	XGEVA	denosumab	Injection	125320	11/18/2010	⤷ Try a Trial	2032-10-22
Amgen, Inc.	REPATHA	evolocumab	Injection	125522	08/27/2015	⤷ Try a Trial	2032-10-22
Amgen, Inc.	REPATHA	evolocumab	Injection	125522	07/08/2016	⤷ Try a Trial	2032-10-22
Regeneron Pharmaceuticals, Inc.	PRALUENT	alirocumab	Injection	125559	07/24/2015	⤷ Try a Trial	2032-10-22
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

Make Better Decisions: Try a trial or see plans & pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.