➤ Get the DrugPatentWatch Daily Briefing

Get Daily Updates on Generic Entry, Litigation, Biosimilars, and more …

Serving leading biopharmaceutical companies globally:

Mallinckrodt
Boehringer Ingelheim
McKinsey
McKesson
Colorcon
Express Scripts

Last Updated: July 26, 2021

DrugPatentWatch Database Preview

Patent: 10,058,630

➤ Get the DrugPatentWatch Daily Briefing

« Back to Dashboard

Summary for Patent: 10,058,630
Title:Methods for inhibiting stenosis, obstruction, or calcification of a stented heart valve or bioprosthesis
Abstract: Methods for inhibiting stenosis, obstruction and/or calcification of a heart valve following implantation in a vessel having a wall are disclosed. In one aspect the method includes providing a bioprosthetic heart valve mounted on an elastical stent; treating the bioprosthetic heart valve with a tissue fixative; coating the stent and the bioprosthetic valve with a coating composition including one or more therapeutic agents; implanting the bioprosthetic valve into the vessel in a diseased natural valve site; eluting the coating composition from the bioprosthetic valve; and inhibiting stenosis, obstruction and/or calcification of the bioprosthetic heart valve by preventing the attachment of stem cells to the bioprosthetic heart valve, the stem cells circulating external and proximate to the bioprosthetic heart valve by activating nitric oxide production (i) in the circulating stem cells, (ii) in an endothelial cell lining covering the bioprosthetic heart valve tissue, (iii) or both.
Inventor(s): Rajamannan; Nalini M. (Chicago, IL)
Assignee: CONCIEVALVE, LLC (Minneapolis, MN)
Application Number:15/601,236
Patent Claims:see list of patent claims

Details for Patent 10,058,630

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Sanofi Aventis PRALUENT alirocumab INJECTABLE;INJECTION 125559 002 2017-04-24 ⤷  Free Forever Trial CONCIEVALVE, LLC (Minneapolis, MN) 2032-10-22 RX Orphan search
Sanofi Aventis PRALUENT alirocumab INJECTABLE;INJECTION 125559 001 2017-04-24 ⤷  Free Forever Trial CONCIEVALVE, LLC (Minneapolis, MN) 2032-10-22 RX Orphan search
Amgen Inc REPATHA evolocumab INJECTABLE;INJECTION 125522 001 2016-07-08 ⤷  Free Forever Trial CONCIEVALVE, LLC (Minneapolis, MN) 2032-10-22 RX Orphan search
Amgen XGEVA denosumab INJECTABLE; SUBCUTANEOUS 125320 002 2010-06-01 ⤷  Free Forever Trial CONCIEVALVE, LLC (Minneapolis, MN) 2032-10-22 RX Orphan search
Amgen PROLIA denosumab INJECTABLE; SUBCUTANEOUS 125320 001 2010-06-01 ⤷  Free Forever Trial CONCIEVALVE, LLC (Minneapolis, MN) 2032-10-22 RX Orphan search
Jubilant Hollisterstier Llc POSITIVE SKIN TEST CONTROL - HISTAMINE histamine INJECTION 103891 1 1995-06-15 ⤷  Free Forever Trial CONCIEVALVE, LLC (Minneapolis, MN) 2032-10-22 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

International Patent Family for US Patent 10,058,630

Country Patent Number Estimated Expiration
World Intellectual Property Organization (WIPO) 2014066365 ⤷  Free Forever Trial
World Intellectual Property Organization (WIPO) 2015061431 ⤷  Free Forever Trial
World Intellectual Property Organization (WIPO) 2016168587 ⤷  Free Forever Trial
World Intellectual Property Organization (WIPO) 2017196844 ⤷  Free Forever Trial
World Intellectual Property Organization (WIPO) 2017196851 ⤷  Free Forever Trial
World Intellectual Property Organization (WIPO) 2018004871 ⤷  Free Forever Trial
>Country >Patent Number >Estimated Expiration

Make Better Decisions: Try a trial or see plans & pricing

Serving leading biopharmaceutical companies globally:

Mallinckrodt
Boehringer Ingelheim
McKinsey
Dow
Baxter
Harvard Business School

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.