Unlock all Features See Plans and Pricing

Serving leading biopharmaceutical companies globally:

Colorcon
Mallinckrodt
Moodys
AstraZeneca
Baxter
Express Scripts

Last Updated: December 3, 2022

Evolocumab - Biologic Drug Details


✉ Email this page to a colleague

« Back to Dashboard

▶ Start for $1
Remove trial restrictions


Recent Clinical Trials for evolocumab

Identify potential brand extensions & biosimilar entrants

SponsorPhase
Hamad Medical CorporationPhase 4
National Natural Science Foundation of ChinaN/A
Nanjing Medical UniversityN/A

See all evolocumab clinical trials

Recent Litigation for evolocumab

Identify key patents and potential future biosimilar entrants

District Court Litigation
Case NameDate
Amgen Inc. v. Sanofi2017-01-11
Amgen Inc. v. Sanofi2014-11-16

See all evolocumab litigation

Pharmacology for evolocumab
Mechanism of ActionPCSK9 Inhibitors
Established Pharmacologic ClassPCSK9 Inhibitor
Chemical StructureAntibodies, Monoclonal
Note on Biologic Patents

Matching patents to biologic drugs is far more complicated than for small-molecule drugs.

DrugPatentWatch employs three methods to identify biologic patents:

  1. Brand-side disclosures in response to biosimilar applications
  2. These patents were identified from disclosures by the brand-side company, in response to a potential biosimilar seeking to launch. They have a high certainty of blocking biosimilar entry. The expiration dates listed are not estimates — they're expiration dates as indicated by the brand-side company.

  3. General brand-side disclosures
  4. These patents were identified from searching drug labels and other general disclosures from the brand-side company. This list may exclude some of the patents which block biosimilar launch, and some of these patents listed may not actually block biosimilar launch. The expiration dates listed for these patents are estimates, based on the grant date of the patent.

  5. Patents from broad patent text search
  6. For completeness, these patents were identified by searching the patent literature for mentions of the branded or ingredient name of the drug. Some of these patents protect the original drug, whereas others may protect follow-on inventions or even inventions casually mentioning the drug. The expiration dates listed for these patents are estimates, based on the grant date of the patent.

1) High Certainty: US Patents for evolocumab Derived from Brand-Side Litigation

No patents found based on brand-side litigation

2) High Certainty: US Patents for evolocumab Derived from Company Disclosures

These patents were obtained from company disclosures
Applicant Tradename Biologic Ingredient Dosage Form BLA Patent No. Estimated Patent Expiration Source
Amgen, Inc. REPATHA evolocumab Injection 125522 See Plans and Pricing 2027-08-23 Company disclosures
Amgen, Inc. REPATHA evolocumab Injection 125522 See Plans and Pricing 2027-08-23 Company disclosures
Amgen, Inc. REPATHA evolocumab Injection 125522 See Plans and Pricing 2027-08-23 Company disclosures
Amgen, Inc. REPATHA evolocumab Injection 125522 See Plans and Pricing 2027-08-23 Company disclosures
Amgen, Inc. REPATHA evolocumab Injection 125522 See Plans and Pricing 2027-08-23 Company disclosures
Amgen, Inc. REPATHA evolocumab Injection 125522 See Plans and Pricing 2027-08-23 Company disclosures
Amgen, Inc. REPATHA evolocumab Injection 125522 See Plans and Pricing 2027-08-23 Company disclosures
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Patent No. >Estimated Patent Expiration >Source

3) Low Certainty: US Patents for evolocumab Derived from Patent Text Search

These patents were obtained by searching patent claims

Supplementary Protection Certificates for evolocumab

Supplementary Protection Certificate SPC Country SPC Expiration SPC Description
300827 Netherlands See Plans and Pricing PRODUCT NAME: ALIROCUMAB; REGISTRATION NO/DATE: EU/1/15/1031 20150925
SPC/GB16/034 United Kingdom See Plans and Pricing PRODUCT NAME: EVOLOCUMAB; REGISTERED: UK EU/1/15/1016 20150721
2016/025 Ireland See Plans and Pricing PRODUCT NAME: EVOLOCUMAB; NAT REGISTRATION NO/DATE: EU/1/15/1016/001 - EU/1/15/1016/005 20150717;
16C0025 France See Plans and Pricing PRODUCT NAME: EVOLOCUMAB; REGISTRATION NO/DATE: EU/1/15/1016 20150721
2016010 Norway See Plans and Pricing PRODUCT NAME: EVOLOCUMAB; REG. NO/DATE: EU/1/15/1016 20150805
300818 Netherlands See Plans and Pricing PRODUCT NAME: EVOLOCUMAB; REGISTRATION NO/DATE: EU/1/15/1016 20150721
CA 2016 00027 Denmark See Plans and Pricing PRODUCT NAME: EVOLOCUMAB; REG. NO/DATE: EU/1/15/1016 20150721
>Supplementary Protection Certificate >SPC Country >SPC Expiration >SPC Description

Make Better Decisions: Try a trial or see plans & pricing

Serving leading biopharmaceutical companies globally:

Medtronic
Johnson and Johnson
Colorcon
Harvard Business School
Merck
McKinsey

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.