trintellix Drug Patent Profile
✉ Email this page to a colleague
When do Trintellix patents expire, and what generic alternatives are available?
Trintellix is a drug marketed by Takeda Pharms Usa and is included in one NDA. There are ten patents protecting this drug and one Paragraph IV challenge.
This drug has two hundred and sixteen patent family members in forty-two countries.
The generic ingredient in TRINTELLIX is vortioxetine hydrobromide. There are sixteen drug master file entries for this compound. Two suppliers are listed for this compound. Additional details are available on the vortioxetine hydrobromide profile page.
DrugPatentWatch® Generic Entry Outlook for Trintellix
Trintellix was eligible for patent challenges on September 30, 2017.
There have been twenty-three patent litigation cases involving the patents protecting this drug, indicating strong interest in generic launch. Recent data indicate that 63% of patent challenges are decided in favor of the generic patent challenger and that 54% of successful patent challengers promptly launch generic drugs.
There are two tentative approvals for the generic drug (vortioxetine hydrobromide), which indicates the potential for near-term generic launch.
Indicators of Generic Entry
Summary for trintellix
| International Patents: | 216 |
| US Patents: | 10 |
| Applicants: | 1 |
| NDAs: | 1 |
| Finished Product Suppliers / Packagers: | 2 |
| Raw Ingredient (Bulk) Api Vendors: | 82 |
| Clinical Trials: | 11 |
| Patent Applications: | 78 |
| Formulation / Manufacturing: | see details |
| Drug Prices: | Drug price information for trintellix |
| Drug Sales Revenues: | Drug sales revenues for trintellix |
| Patent Litigation and PTAB cases: | See patent lawsuits and PTAB cases for trintellix |
| What excipients (inactive ingredients) are in trintellix? | trintellix excipients list |
| DailyMed Link: | trintellix at DailyMed |
See drug prices for trintellix
Recent Clinical Trials for trintellix
Identify potential brand extensions & 505(b)(2) entrants
| Sponsor | Phase |
|---|---|
| Seasons Biotechnology (Taizhou) Co., Ltd. | Phase 1 |
| H. Lundbeck A/S | Phase 3 |
| Todd Doyle | Phase 4 |
Anatomical Therapeutic Chemical (ATC) Classes for trintellix
Paragraph IV (Patent) Challenges for TRINTELLIX
| Tradename | Dosage | Ingredient | Strength | NDA | ANDAs Submitted | Submissiondate |
|---|---|---|---|---|---|---|
| TRINTELLIX | Tablets | vortioxetine hydrobromide | 5 mg, 10 mg, 15 mg and 20 mg | 204447 | 15 | 2017-10-02 |
US Patents and Regulatory Information for trintellix
trintellix is protected by ten US patents and three FDA Regulatory Exclusivities.
Patents protecting trintellix
1-[2-(2,4-dimeihylphenylsulfanyl)-phenyl]piperazine as a compound with combined serotonin reuptake, 5-HT3 and 5-HT1A activity for the treatment of cognitive impairment
Patent Number: ⤷ Sign Up
Patent Expiration: ⤷ Sign Up
Phenyl-piperazine derivatives as serotonin reuptake inhibitors
Patent Number: ⤷ Sign Up
Patent Expiration: ⤷ Sign Up
1-[2-(2,4-dimethylphenylsulfanyl)-phenyl] piperazine as a compound with combined serotonin reuptake, 5-HT3 and 5-HT1A activity for the treatment of cognitive impairment
Patent Number: ⤷ Sign Up
Patent Expiration: ⤷ Sign Up
1-[2-(2,4 dimethylphenylsulfanyl)-phenyl]piperazine as a compound with combined serotonin reuptake, 5-HT3 and 5-HT1a activity for the treatment of cognitive impairment
Patent Number: ⤷ Sign Up
Patent Expiration: ⤷ Sign Up
1-[2-(2,4-dimethylphenylsulfanyl)-phenyl]piperazine as a compound with combined serotonin reuptake, 5-HT.sub.3 and 5-HT.sub.1A activity for the treatment of cognitive impairment
Patent Number: ⤷ Sign Up
Patent Expiration: ⤷ Sign Up
1-[2-(2,4 dimethylphenylsulfanyl)-phenyl]piperazine as a compound with combined serotonin reuptake, 5-HT.sub.3 and 5-HT.sub.1A activity for the treatment of cognitive impairment
Patent Number: ⤷ Sign Up
Patent Expiration: ⤷ Sign Up
1-[2-(2,4 dimethylphenylsulfanyl)-phenyl]piperazine as a compound with combined serotonin reuptake, 5-HT.sub.3 and 5-HT.sub.1A activity for the treatment of cognitive impairment
Patent Number: ⤷ Sign Up
Patent Expiration: ⤷ Sign Up
1-[2-(2,4 dimethylphenylsulfanyl)-phenyl]piperazine as a compound with combined serotonin reuptake, 5-HT3 and 5-HT1a activity for the treatment of cognitive impairment
Patent Number: ⤷ Sign Up
Patent Expiration: ⤷ Sign Up
Therapeutic uses of compounds having combined SERT, 5-HT.sub.3 and 5-HT.sub.1A activity
Patent Number: ⤷ Sign Up
Patent Expiration: ⤷ Sign Up
1-[2-(2,4-dimethylphenylsulfanyl)-phenyl]piperazine as a compound with combined serotonin reuptake, 5-HT.sub.3 and 5-HT.sub.1A activity for the treatment of cognitive impairment
Patent Number: ⤷ Sign Up
Patent Expiration: ⤷ Sign Up
FDA Regulatory Exclusivity protecting trintellix
ADDITION OF CLINICAL INFORMATION OBTAINED FROM A PEDIATRIC TRIAL TO SECTION 8.4 OF THE LABELING
Exclusivity Expiration: ⤷ Sign Up
INFORMATION ADDED TO SECTION 8.4 OF THE LABELING TO DESCRIBE THE RESULTS FROM PEDIATRIC STUDIES
Exclusivity Expiration: ⤷ Sign Up
PEDIATRIC EXCLUSIVITY
Exclusivity Expiration: ⤷ Sign Up
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Exclusivity Expiration |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Takeda Pharms Usa | TRINTELLIX | vortioxetine hydrobromide | TABLET;ORAL | 204447-004 | Sep 30, 2013 | RX | Yes | Yes | ⤷ Sign Up | ⤷ Sign Up | Y | ⤷ Sign Up | |||
| Takeda Pharms Usa | TRINTELLIX | vortioxetine hydrobromide | TABLET;ORAL | 204447-003 | Sep 30, 2013 | DISCN | Yes | No | ⤷ Sign Up | ⤷ Sign Up | Y | ⤷ Sign Up | |||
| Takeda Pharms Usa | TRINTELLIX | vortioxetine hydrobromide | TABLET;ORAL | 204447-004 | Sep 30, 2013 | RX | Yes | Yes | ⤷ Sign Up | ⤷ Sign Up | Y | ⤷ Sign Up | |||
| Takeda Pharms Usa | TRINTELLIX | vortioxetine hydrobromide | TABLET;ORAL | 204447-004 | Sep 30, 2013 | RX | Yes | Yes | ⤷ Sign Up | ⤷ Sign Up | Y | ⤷ Sign Up | |||
| Takeda Pharms Usa | TRINTELLIX | vortioxetine hydrobromide | TABLET;ORAL | 204447-004 | Sep 30, 2013 | RX | Yes | Yes | ⤷ Sign Up | ⤷ Sign Up | ⤷ Sign Up | ||||
| Takeda Pharms Usa | TRINTELLIX | vortioxetine hydrobromide | TABLET;ORAL | 204447-003 | Sep 30, 2013 | DISCN | Yes | No | ⤷ Sign Up | ⤷ Sign Up | Y | ⤷ Sign Up | |||
| >Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Exclusivity Expiration |
Expired US Patents for trintellix
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | Patent No. | Patent Expiration |
|---|---|---|---|---|---|---|---|
| Takeda Pharms Usa | TRINTELLIX | vortioxetine hydrobromide | TABLET;ORAL | 204447-001 | Sep 30, 2013 | ⤷ Sign Up | ⤷ Sign Up |
| Takeda Pharms Usa | TRINTELLIX | vortioxetine hydrobromide | TABLET;ORAL | 204447-002 | Sep 30, 2013 | ⤷ Sign Up | ⤷ Sign Up |
| Takeda Pharms Usa | TRINTELLIX | vortioxetine hydrobromide | TABLET;ORAL | 204447-004 | Sep 30, 2013 | ⤷ Sign Up | ⤷ Sign Up |
| Takeda Pharms Usa | TRINTELLIX | vortioxetine hydrobromide | TABLET;ORAL | 204447-003 | Sep 30, 2013 | ⤷ Sign Up | ⤷ Sign Up |
| >Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >Patent No. | >Patent Expiration |
International Patents for trintellix
When does loss-of-exclusivity occur for trintellix?
Based on analysis by DrugPatentWatch, the following patents block generic entry in the countries listed below:
Argentina
Patent: 1481
Estimated Expiration: ⤷ Sign Up
Patent: 5797
Estimated Expiration: ⤷ Sign Up
Australia
Patent: 07260355
Patent: 1- [2- (2, 4-dimethylphenylsulfanyl) -phenyl] piperazine as a compound with combined serotonin reuptake, 5-HT3 and 5-HT1A activity for the treatment of cognitive impairment
Estimated Expiration: ⤷ Sign Up
Patent: 08228638
Estimated Expiration: ⤷ Sign Up
Austria
Patent: 95745
Estimated Expiration: ⤷ Sign Up
Patent: 40941
Estimated Expiration: ⤷ Sign Up
Brazil
Patent: 0713425
Estimated Expiration: ⤷ Sign Up
Patent: 0808941
Estimated Expiration: ⤷ Sign Up
Patent: 2020011899
Estimated Expiration: ⤷ Sign Up
Patent: 2020011920
Estimated Expiration: ⤷ Sign Up
Canada
Patent: 55212
Patent: 1-[2-(2, 4-DIMETHYLPHENYLSULFANYL)-PHENYL]PIPERAZINE COMME COMPOSE PRESENTANT UNE ACTIVITE SUR LA SEROTONINE, 5-HT3 ET 5-HT1A POUR LE TRAITEMENT DU DEFICIT COGNITIF (1- [2- (2, 4-DIMETHYLPHENYLSULFANYL) -PHENYL] PIPERAZINE AS A COMPOUND WITH COMBINED SEROTONIN REUPTAKE, 5-HT3 AND 5-HT1A ACTIVITY FOR THE TREATMENT OF COGNITIVE IMPAIRMENT)
Estimated Expiration: ⤷ Sign Up
Patent: 84571
Estimated Expiration: ⤷ Sign Up
Chile
Patent: 08000795
Estimated Expiration: ⤷ Sign Up
Patent: 11001610
Estimated Expiration: ⤷ Sign Up
China
Patent: 1472906
Patent: 1- [2- (2, 4-dimethylphenylsulfanyl) -phenyl] piperazine as a compound with combined serotonin reuptake, 5-HT3 and 5-HT1A activity for the treatment of cognitive impairment
Estimated Expiration: ⤷ Sign Up
Patent: 1636161
Patent: 1- [2-(2,4-dimethylphenylsulfanyl)-phenyl] piperazine as a compound with combined serotonin reuptake, 5-ht3 and 5-ht1a activity for the treatment of pain or residual symptoms in depression relating to
Estimated Expiration: ⤷ Sign Up
Patent: 2614179
Patent: 1- [2- (2,4-dimethylphenylsulfanyl)-phenyl] piperazine as a compound with combined serotonin reuptake, 5-ht3 and 5-ht1a activity for the treatment of cognitive impairment
Estimated Expiration: ⤷ Sign Up
Patent: 2617513
Patent: 1- [2- (2,4-dimethylphenylsulfanyl)-phenyl] piperazine as a compound with combined serotonin reuptake, 5-HT3 AND 5-HT1A activity for the treatment of cognitive impairment
Estimated Expiration: ⤷ Sign Up
Patent: 3948597
Patent: 1-[2-(2,4-dimethylphenylsulfanyl)phenyl]piperazine used for treatment of pain or depression residual symptoms related with sleep and cognition
Estimated Expiration: ⤷ Sign Up
Colombia
Patent: 20962
Estimated Expiration: ⤷ Sign Up
Croatia
Patent: 0110058
Estimated Expiration: ⤷ Sign Up
Patent: 0120173
Estimated Expiration: ⤷ Sign Up
Cyprus
Patent: 11183
Estimated Expiration: ⤷ Sign Up
Patent: 12635
Estimated Expiration: ⤷ Sign Up
Denmark
Patent: 44043
Estimated Expiration: ⤷ Sign Up
Patent: 42193
Estimated Expiration: ⤷ Sign Up
Eurasian Patent Organization
Patent: 5287
Patent: 1-[2-(2,4-ДИМЕТИЛФЕНИЛСУЛЬФАНИЛ)ФЕНИЛ]ПИПЕРАЗИН В КАЧЕСТВЕ СОЕДИНЕНИЯ С СОЧЕТАНИЕМ АКТИВНОСТИ В ОТНОШЕНИИ ПОВТОРНОГО ЗАХВАТА СЕРОТОНИНА, 5-НТИ 5-НТДЛЯ ЛЕЧЕНИЯ КОГНИТИВНОГО НАРУШЕНИЯ (1- [2- (2, 4-DIMETHYLPHENYLSULFANYL) -PHENYL] PIPERAZINE AS A COMPOUND WITH COMBINED SEROTONIN REUPTAKE, 5-HTAND 5-HTACTIVITY FOR THE TREATMENT OF COGNITIVE IMPAIRMENT)
Estimated Expiration: ⤷ Sign Up
Patent: 7058
Estimated Expiration: ⤷ Sign Up
Patent: 0970018
Patent: 1-[2-(2,4-ДИМЕТИЛФЕНИЛСУЛЬФАНИЛ)ФЕНИЛ]ПИПЕРАЗИН В КАЧЕСТВЕ СОЕДИНЕНИЯ С СОЧЕТАНИЕМ АКТИВНОСТИ В ОТНОШЕНИИ ПОВТОРНОГО ЗАХВАТА СЕРОТОНИНА, 5-НТ3 И 5-НТ1А ДЛЯ ЛЕЧЕНИЯ КОГНИТИВНОГО НАРУШЕНИЯ
Estimated Expiration: ⤷ Sign Up
Patent: 0970870
Estimated Expiration: ⤷ Sign Up
European Patent Office
Patent: 44043
Patent: 1-[2-(2, 4-DIMETHYLPHENYLSULFANYL)-PHENYL]PIPERAZINE COMME COMPOSE PRESENTANT UNE ACTIVITE SUR LA SEROTONINE, 5-HT3 ET 5-HT1A POUR LE TRAITEMENT DU DEFICIT COGNITIF (1- Ý[- (2, 4-DIMETHYLPHENYLSULFANYL) -PHENYL]PIPERAZINE AS A COMPOUND WITH COMBINED SEROTONIN REUPTAKE, 5-HT3 AND 5-HT1A ACTIVITY FOR THE TREATMENT OF COGNITIVE IMPAIRMENT)
Estimated Expiration: ⤷ Sign Up
Patent: 42193
Patent: 1-[2-(2,4-DIMÉTHYLPHÉNYLSULFANYL)PHÉNYL]PIPÉRAZINE EN TANT QUE COMPOSÉ AVEC ACTIVITÉ COMBINÉ DU RECAPTAGE DE LA SEROTONINE, 5-HT3 ET 5-HT1A POUR LE TRAITEMENT DE LA DOLEUR OU DE SYMPTÔMES RÉSIDUELLES EN DEPRESSION CONCERNANT LE SOMMEIL ET LA COGNITION (1-[2-(2,4-DIMETHYLPHENYLSULFANYL)PHENYL]PIPERAZINE AS A COMPOUND WITH COMBINED SEROTONIN REUPTAKE, 5-HT3 AND 5-HT1A ACTIVITY FOR THE TREATMENT OF PAIN OR RESIDUAL SYMPTOMS IN DEPRESSION RELATING TO SLEEP AND COGNITION)
Estimated Expiration: ⤷ Sign Up
Patent: 39201
Estimated Expiration: ⤷ Sign Up
Finland
Patent: 44043
Estimated Expiration: ⤷ Sign Up
Germany
Patent: 2008004643
Estimated Expiration: ⤷ Sign Up
Hong Kong
Patent: 34483
Patent: 1- [2- (2, 4-DIMETHYLPHENYLSULFANYL)-PHENYL] PIPERAZINE AS A COMPOUND WITH COMBINED SEROTONIN REUPTAKE, 5-HT3 AND 5-HT1A ACTIVITY FOR THE TREATMENT OF COGNITIVE IMPAIRMENT
Estimated Expiration: ⤷ Sign Up
Patent: 71951
Estimated Expiration: ⤷ Sign Up
Patent: 72014
Estimated Expiration: ⤷ Sign Up
Israel
Patent: 5511
Patent: 1- [2-(2, 4-דימתילפנילסולפניל)-פניל]פיפרזין כתרכובת גבישית ושימושו להכנת תרופה לטיפול בליקוי קוגניטיבי (1-[2-(2,4-dimethylphenylsulfanyl)-phenyl] piperazine which compound is crystalline and use thereof for the preparation of a medicament for treatment of cognitive impairment)
Estimated Expiration: ⤷ Sign Up
Patent: 0956
Patent: 1-[2-(2,4-דימתילפנילסולפניל)-פניל]פיפרזין לטיפול בכאב (1-[2-(2,4-dimethylphenylsulfanyl)-phenyl]piperazine for use in the treatment of pain)
Estimated Expiration: ⤷ Sign Up
Japan
Patent: 90013
Estimated Expiration: ⤷ Sign Up
Patent: 71790
Estimated Expiration: ⤷ Sign Up
Patent: 02929
Estimated Expiration: ⤷ Sign Up
Patent: 63609
Estimated Expiration: ⤷ Sign Up
Patent: 01742
Estimated Expiration: ⤷ Sign Up
Patent: 24082
Estimated Expiration: ⤷ Sign Up
Patent: 79035
Estimated Expiration: ⤷ Sign Up
Patent: 09541216
Estimated Expiration: ⤷ Sign Up
Patent: 10090165
Patent: 1-[2-(2,4-DIMETHYLPHENYLSULFANYL)-PHENYL]PIPERAZINE AS COMPOUND WITH COMBINED SEROTONIN REUPTAKE, 5-HT3 AND 5-HT1A ACTIVITY FOR TREATMENT OF COGNITIVE IMPAIRMENT
Estimated Expiration: ⤷ Sign Up
Patent: 10521501
Estimated Expiration: ⤷ Sign Up
Patent: 13056933
Patent: 1-[2-(2,4-DIMETHYLPHENYLSULFANYL)-PHENYL] PIPERAZINE AS COMPOUND WITH COMBINED SEROTONIN REUPTAKE, 5-HT3 AND 5-HT1A ACTIVITY FOR TREATMENT OF COGNITIVE IMPAIRMENT
Estimated Expiration: ⤷ Sign Up
Patent: 15157872
Estimated Expiration: ⤷ Sign Up
Patent: 17008086
Estimated Expiration: ⤷ Sign Up
Patent: 18199689
Estimated Expiration: ⤷ Sign Up
Patent: 20152732
Estimated Expiration: ⤷ Sign Up
Patent: 23009175
Estimated Expiration: ⤷ Sign Up
Malaysia
Patent: 0448
Patent: 1- [2-(2,4-DIMETHYLPHENYLSULFANYL)-PHENYL] PIPERAZINE AS A COMPOUND WITH COMBINED SEROTONIN REUPTAKE, 5-HT3 AND 5-HT1A ACTIVITY FOR THE TREATMENT OF PAIN OR RESIDUAL SYMPTOMS IN DEPRESSION RELATING TO SLEEP AND COGNITION
Estimated Expiration: ⤷ Sign Up
Patent: 0647
Patent: 1-[2-(2,4-DIMETHYLPHENYLSULFANYL)-PHENYL] PIPERAZINE AS A COMPOUND WITH COMBINED SEROTONIN REUPTAKE, 5-HT3 AND 5-HT1A ACTIVITY FOR THE TREATMENT OF COGNITIVE IMPAIRMENT
Estimated Expiration: ⤷ Sign Up
Mexico
Patent: 08016141
Patent: 1-[2-(2,4-DIMETILFENILSULFANIL)-FENIL] PIPERAZINA COMO UN COMPUESTO CON ACTIVIDAD COMBINADA DE RECAPTACIÓN DE SEROTONINA, 5-HT3 Y 5-HT1A.PARA EL TRATAMIENTO DE DAÑO COGNITIVO. (1- [2- (2, 4-DIMETHYLPHENYLSULFANYL) -PHENYL] PIPERAZINE AS A COMPOUND WITH COMBINED SEROTONIN REUPTAKE, 5-HT3 AND 5-HT1A ACTIVITY FOR THE TREATMENT OF COGNITIVE IMPAIRMENT.)
Estimated Expiration: ⤷ Sign Up
Patent: 09009672
Estimated Expiration: ⤷ Sign Up
Morocco
Patent: 575
Patent: 1-[2-(2, 4-DIMÉTHYLPHÉNYLSULFANYL)-PHÉNYL]PIPÉRAZINE COMME COMPOSÉ PRÉSENTANT UNE ACTIVITÉ SUR LA SÉROTONINE, 5-HT3 ET 5-HT1A POUR LE TRAITEMENT DU DÉFICIT COGNITIF
Estimated Expiration: ⤷ Sign Up
New Zealand
Patent: 2986
Patent: 1- [2- (2, 4-DIMETHYLPHENYLSULFANYL) -PHENYL] PIPERAZINE AS A COMPOUND WITH COMBINED SEROTONIN REUPTAKE, 5-HT3 AND 5-HT1A ACTIVITY FOR THE TREATMENT OF COGNITIVE IMPAIRMENT
Estimated Expiration: ⤷ Sign Up
Patent: 9721
Patent: 1-[2-(2,4-dimethylphenylsulfanyl)-phenyl] piperazine as a compound with combined serotonin reuptake, 5-HT3 and 5-HT1A activity for the treatment of pain or residual symptoms in depression relating to sleep and cognition
Estimated Expiration: ⤷ Sign Up
Norway
Patent: 3929
Estimated Expiration: ⤷ Sign Up
Patent: 090229
Estimated Expiration: ⤷ Sign Up
Poland
Patent: 44043
Estimated Expiration: ⤷ Sign Up
Patent: 42193
Estimated Expiration: ⤷ Sign Up
Portugal
Patent: 44043
Estimated Expiration: ⤷ Sign Up
Patent: 42193
Estimated Expiration: ⤷ Sign Up
Serbia
Patent: 560
Patent: 1-[2-(2,4-DIMETILFENILSULFANIL)FENIL]PIPERAZIN KAO JEDINJENJE SA KOMBINOVANOM AKTIVNOŠĆU VEZANOM ZA PONOVNO PREUZIMANJE SEROTONINA I 5-HT3 I 5HT1A AKTIVNOŠĆU, ZA LEČENJE BOLA ILI REZIDUALNIH SIMPTOMA U DEPRESIJI VEZANIH ZA SAN I KOGNICIJU (1-[2-(2,4-DIMETHYLPHENYLSULFANYL)PHENYL]PIPERAZINE AS A COMPOUND WITH COMBINED SEROTONIN REUPTAKE, 5-HT3 AND 5-HT1A ACTIVITY FOR THE TREATMENT OF PAIN OR RESIDUAL SYMPTOMS IN DEPRESSION RELATING TO SLEEP AND COGNITION)
Estimated Expiration: ⤷ Sign Up
Patent: 205
Patent: 1-[2-(2,4-DIMETILFENILSULFANIL)-FENIL]PIPERAZIN KAO JEDINJENJE SA KOMBINOVANOM AKTIVNOŠĆU PONOVNOG UZIMANJA SEROTONINA, 5-HT3 I 5-HT1A, ZA TRETMAN KOGNITIVNIH OŠTEĆENJA (1-[2-(2,4-DIMETHYLPHENYLSULFANYL)-PHENYL]PIPERAZINE AS A COMPOUND WITH COMBINED SEROTONIN REUPTAKE, 5-HT3 AND 5-HT1A ACTIVITY FOR THE TREATMENT OF COGNITIVE IMPAIRMENT)
Estimated Expiration: ⤷ Sign Up
Slovenia
Patent: 44043
Estimated Expiration: ⤷ Sign Up
Patent: 42193
Estimated Expiration: ⤷ Sign Up
South Africa
Patent: 0810017
Patent: 1- [2- (2, 4-Dimethylphenylsulfanyl) -phenyl] piperazine as a compound with combined serotonin Reuptake, 5-HT3 and 5-HT1A activity for the treatment of cognitive impairment
Estimated Expiration: ⤷ Sign Up
South Korea
Patent: 1445514
Estimated Expiration: ⤷ Sign Up
Patent: 1459168
Estimated Expiration: ⤷ Sign Up
Patent: 1627901
Estimated Expiration: ⤷ Sign Up
Patent: 090028712
Patent: 1-[2-(2,4-DIMETHYLPHENYLSULFANYL)-PHENYL]PIPERAZINE AS A COMPOUND WITH COMBINED SEROTONIN REUPTAKE, 5-HT3 AND 5-HT1A ACTIVITY FOR THE TREATMENT OF COGNITIVE IMPAIRMENT
Estimated Expiration: ⤷ Sign Up
Patent: 090125251
Patent: 1-[2-(2,4-DIMETHYLPHENYLSULFANYL)-PHENYL]PIPERAZINE AS A COMPOUND WITH COMBINED SEROTONIN REUPTAKE, 5-HT3 AND 5-HT1A ACTIVITY FOR THE TREATMENT OF PAIN OR RESIDUAL SYMPTOMS IN DEPRESSION RELATING TO SLEEP AND COGNITION
Estimated Expiration: ⤷ Sign Up
Patent: 130079619
Patent: 1-[2-(2,4-DIMETHYLPHENYLSULFANYL)-PHENYL]PIPERAZINE AS A COMPOUND WITH COMBINED SEROTONIN REUPTAKE, 5-HT3 AND 5-HT1A ACTIVITY FOR THE TREATMENT OF COGNITIVE IMPAIRMENT
Estimated Expiration: ⤷ Sign Up
Patent: 130133078
Patent: 1-[2-(2,4-DIMETHYLPHENYLSULFANYL)-PHENYL]PIPERAZINE AS A COMPOUND WITH COMBINED SEROTONIN REUPTAKE, 5-HT3 AND 5-HT1A ACTIVITY FOR THE TREATMENT OF COGNITIVE IMPAIRMENT
Estimated Expiration: ⤷ Sign Up
Spain
Patent: 55434
Estimated Expiration: ⤷ Sign Up
Patent: 79200
Estimated Expiration: ⤷ Sign Up
Patent: 32102
Estimated Expiration: ⤷ Sign Up
Taiwan
Patent: 43091
Estimated Expiration: ⤷ Sign Up
Patent: 0817340
Estimated Expiration: ⤷ Sign Up
Patent: 0848411
Estimated Expiration: ⤷ Sign Up
Tunisia
Patent: 08460
Patent: 1- [2- (2, 4-DIMETHYLPHENYLSULFANYL) -PHENYL] PIPERAZINE AS A COMPOUND WITH COMBINED SEROTONIN REUPTAKE, 5-HT3 AND 5-HT1A ACTIVITY FOR THE TREATMENT OF COGNITIVE IMPAIRMENT
Estimated Expiration: ⤷ Sign Up
Ukraine
Patent: 250
Estimated Expiration: ⤷ Sign Up
Patent: 392
Patent: 1-[2-(2,4-ДИМЕТИЛФЕНИЛСУЛЬФАНИЛ)ФЕНИЛ]ПИПЕРАЗИН КАК СОЕДИНЕНИЕ С КОМБИНИРОВАННОЙ АКТИВНОСТЬЮ В ОТНОШЕНИИ ОБРАТНОГО ЗАХВАТА СЕРОТОНИНА, 5-НТ3 И 5-НТ1A ДЛЯ ЛЕЧЕНИЯ БОЛИ;1-[2-(2,4-ДИМЕТИЛФЕНІЛСУЛЬФАНІЛ)ФЕНІЛ]ПІПЕРАЗИН ЯК СПОЛУКА З КОМБІНОВАНОЮ АКТИВНІСТЮ СТОСОВНО ЗВОРОТНОГО ЗАХОПЛЕННЯ СЕРОТОНІНУ, 5-HT3 ТА 5-HT1A ДЛЯ ЛІКУВАННЯ БОЛЮ (1-[2-(2,4-DIMETHYLPHENYLSULFANYL)-PHENYL]PIPERAZINE AS A COMPOUND WITH COMBINED SEROTONIN REUPTAKE, 5-HT3 AND 5-HT1A ACTIVITY FOR THE TREATMENT OF PAIN)
Estimated Expiration: ⤷ Sign Up
Generics may enter earlier, or later, based on new patent filings, patent extensions, patent invalidation, early generic licensing, generic entry preferences, and other factors.
See the table below for additional patents covering trintellix around the world.
| Country | Patent Number | Title | Estimated Expiration |
|---|---|---|---|
| Canada | 2462110 | DERIVES DE PHENYL-PIPERAZINE EN TANT QU'INHIBITEURS DU RECAPTAGE DE LA SEROTONINE (PHENYL-PIPERAZINE DERIVATIVES AS SEROTONIN REUPTAKE INHIBITORS) | ⤷ Sign Up |
| Iceland | 7164 | ⤷ Sign Up | |
| Ukraine | 101341 | ТЕРАПЕВТИЧЕСКИЕ ПРИМЕНЕНИЯ СОЕДИНЕНИЙ, КОТОРЫЕ ИМЕЮТ КОМБИНИРОВАННУЮ АКТИВНОСТЬ В ОТНОШЕНИИ SERT, 5-НТ3 И 5-НТ1A;ТЕРАПЕВТИЧНІ ЗАСТОСУВАННЯ СПОЛУК, ЩО МАЮТЬ КОМБІНОВАНУ АКТИВНІСТЬ СТОСОВНО SERT, 5-HT3 ТА 5-HT1A (Normal;heading 1;heading 2;heading 3;THERAPEUTIC USES OF COMPOUNDS HAVING COMBINED SERT, 5-HT3 AND 5-HT1A ACTIVITY) | ⤷ Sign Up |
| China | 1561336 | ⤷ Sign Up | |
| Hong Kong | 1172014 | 作為用於治療認知損傷的、具有結合的對血清素再吸收、 活性的化合物的 -二甲基苯基硫烷基 -苯基 哌嗪 (1- [2- (2, 4-DIMETHYLPHENYLSULFANYL) -PHENYL] PIPERAZINE AS A COMPOUND WITH COMBINED SEROTONIN REUPTAKE, 5-HT3 AND 5-HT1A ACTIVITY FOR THE TREATMENT OF COGNITIVE IMPAIRMENT 5-HT3 5-HT1A 1-[2-(24-)-]) | ⤷ Sign Up |
| South Korea | 101536023 | ⤷ Sign Up | |
| >Country | >Patent Number | >Title | >Estimated Expiration |
Supplementary Protection Certificates for trintellix
| Patent Number | Supplementary Protection Certificate | SPC Country | SPC Expiration | SPC Description |
|---|---|---|---|---|
| 1436271 | 14C0033 | France | ⤷ Sign Up | PRODUCT NAME: VORTIOXETINE OU L'UN DE SES SELS D'ADDITION D'ACIDE PHARMACEUTIQUEMENT ACCEPTABLES; REGISTRATION NO/DATE: EU/1/13/891 20131218 |
| 1436271 | CR 2014 00030 | Denmark | ⤷ Sign Up | PRODUCT NAME: VORTIOXETIN ELLER FARMACEUTISK ACCEPTABLE SYREADDITIONSSALTE DERAF, HERUNDER VORTIOXETINHYDROBROMID; REG. NO/DATE: EU/1/13/891 20131218 |
| 1436271 | 302 50003-2014 | Slovakia | ⤷ Sign Up | OWNER(S): H. LUNDBECK A/S, VALBY, DK |
| 1436271 | C 2014 023 | Romania | ⤷ Sign Up | PRODUCT NAME: VORTIOXETINA SAU O SARE DE ADITIE ACIDA A ACESTEIAACCEPTABILA FARMACEUTIC1-[2-(2,4-DIMETILFENILSULFANIL)FENIL]PIPERAZINA; NATIONAL AUTHORISATION NUMBER: EU/1/13/891; DATE OF NATIONAL AUTHORISATION: 20131218; NUMBER OF FIRST AUTHORISATION IN EUROPEAN ECONOMIC AREA (EEA): EU/1/13/891; DATE OF FIRST AUTHORISATION IN EEA: 20131218 |
| 1436271 | 2014C/036 | Belgium | ⤷ Sign Up | PRODUCT NAME: VORTIOXETINE; AUTHORISATION NUMBER AND DATE: EU/1/13/891 20131220 |
| 1436271 | PA2014013,C1436271 | Lithuania | ⤷ Sign Up | PRODUCT NAME: VORTIOKSETINAS ARBA JO FARMACINIU POZIURIU PRIIMTINA RUGSTIES PRISIJUNGIMO DRUSKA; REGISTRATION NO/DATE: EU/1/13/891 20131218 |
| >Patent Number | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration | >SPC Description |
Make Better Decisions: Try a trial or see plans & pricing
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.
ISSN: 2162-2639
Privacy and Cookies
Terms & Conditions
Site Map
DrugPatentWatch Alternatives
LOE / Major Patent Expirations 2024 - 2025
NCE-1 Patent Challenge Dates 2024 - 2025
Trigger-based marketing for the life sciences
Get DrugPatentWatch Business Intelligence Reports at Amazon.com
DrugChatter - AI-based answers to questions about drugs
RxJam - HIPAA-ready chat for life sciences
Friedman, Yali. "DrugPatentWatch" DrugPatentWatch, thinkBiotech, 2024, www.DrugPatentWatch.com.
See Primary Research Papers Citing DrugPatentWatch
Follow DrugPatentWatch:
