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Generated: December 10, 2018

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ZERVIATE Drug Profile

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When do Zerviate patents expire, and what generic alternatives are available?

Zerviate is a drug marketed by Eyevance Pharms and is included in one NDA. There are four patents protecting this drug.

This drug has thirteen patent family members in five countries.

The generic ingredient in ZERVIATE is cetirizine hydrochloride. There are thirty-nine drug master file entries for this compound. One hundred and sixty-one suppliers are listed for this compound. Additional details are available on the cetirizine hydrochloride profile page.

Summary for ZERVIATE
International Patents:13
US Patents:4
Applicants:1
NDAs:1
Bulk Api Vendors: 173
Patent Applications: 4,029
Formulation / Manufacturing:see details
DailyMed Link:ZERVIATE at DailyMed
Drug patent expirations by year for ZERVIATE
Medical Subject Heading (MeSH) Categories for ZERVIATE
Synonyms for ZERVIATE
(+-)-(2-(4-(p-Chloro-alpha-phenylbenzyl)-1-piperazinyl)ethoxy)acetic acid, dihydrochloride
(+) {2-[4-(alpha-phenyl-p-chlorobenzyl)-piperazine-1-yl] -ethoxy}-acetic acid dihydrochloride
(+/-)-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl] ethoxy]acetic acid, dihydrochloride
(+/-){2-[4-(alpha-phenyl-p-chlorobenzyl)-piperazin-1-yl]-ethoxy}-acetic acid dihydrochloride
(2-(4-((4-Chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)acetic acid
(2-(4-((4-Chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)acetic acid dihydrochloride
(2-{4-[(4-Chloro-phenyl)-phenyl-methyl]-piperazin-1-yl}-ethoxy)-acetic acid
(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid
(2-{4-[(4-Chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid (2HCl)
(R) -2-[2-[4-[(4-Chlorophenyl) Phenylmethyl] Piperazin-1-yl]Ethoxy]Acetic Acid Dihydrochloride
(R)-2-(2-(4-((4-Chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)acetic acid dihydrochloride
(RS)-{2-[4-(alpha-phenyl-p-chlorobenzyl)-piperazin-1-yl]ethoxy }-acetic acid dihydrochloride
(RS)-{2-[4-(alpha-phenyl-p-chlorobenzyl)-piperazin-1-yl]ethoxy}-acetic acid dihydrochloride
[(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethyl)oxy]acetic acid
[2-[4-[(4-Chlorophenyl)-phenyl methyl]-1-piperazinyl] ethoxy] acetic acid
[2-[4-[(4-chlorophenyl)phenylmethyl] 1-piperazinyl]-ethoxy] acetic acid
[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]-ethoxy]acetic acid
[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]acetic acid
[2-[4-[(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]acetic acid dihydrochloride
[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]aceticaciddihydrochloride
110271-EP2284166A1
110271-EP2298415A1
130018-82-5
2-(2-(4-((4-Chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)acetic acid
2-(2-(4-((4-Chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)acetic acid dihydrochloride
2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)acetic acid hydrochloride
2-(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid
2-(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazino}ethoxy)acetic acid
2-(2-{4-[(4-chlorophenyl)phenylmethyl]piperazinyl}ethoxy)acetic acid
2-[2-[4-[(4-chlorophenyl)-phenyl-methyl]piperazin-1-yl]ethoxy]acetic acid
2-[2-[4-[(4-chlorophenyl)-phenyl-methyl]piperazin-1-yl]ethoxy]acetic acid dihydrichloride
2-[2-[4-[(4-chlorophenyl)-phenyl-methyl]piperazin-1-yl]ethoxy]acetic acid dihydrochloride
2-[2-[4-[(4-chlorophenyl)-phenyl-methyl]piperazin-1-yl]ethoxy]ethanoic acid dihydrochloride
2-[2-[4-[(4-chlorophenyl)-phenylmethyl]-1-piperazinyl]ethoxy]acetic acid dihydrochloride
2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]acetic acid
2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]acetic acid dihydrochloride
2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]acetic acid;dihydrochloride
2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]acetic acid
24161-EP2272832A1
24161-EP2281815A1
24161-EP2295409A1
24161-EP2301933A1
24161-EP2305640A2
24161-EP2311827A1
24161-EP2314590A1
2469AC
798544-25-9
81C510
83881-51-0
83881-51-0 (Parent)
83881-52-1
83881-52-1 (di-hydrochloride)
881C510
881C521
A10107
A840675
AB0008484
AB0019096
AB1009381
AC-1600
AC-5545
AC1L1E7T
AC1L1IJL
AC1Q768B
Acetic acid, (2-(4-((4-chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)-
Acetic acid, (2-(4-((4-chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)-, dihydrochloride
Acetic acid, (2-(4-((4-chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)-, dihydrochloride, (+-)-
Acetic acid, [2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-
ACETIC ACID,[2-[4-[(R)-(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINYL]ETHOXY]-,MONOHYDROCHLORIDE
AK-57294
AK108356
AK307945
AKOS000280979
AKOS003589059
AKOS016002146
AKOS016340521
AKOS021729457
Alercet
Alergex
Alerid
Alerlisin
Alertisin
Allergy relief
Alleroff
AN-10906
AN-14770
AN-15756
ANW-58920
ANW-69482
API0001938
API0025650
Apo-Cetirizine
AX8022801
AX8041242
AX8323094
BB_SC-2161
BBL009968
BDBM22890
Benaday
BG0436
BPBio1_000469
BRD-A42571354-300-05-4
BSPBio_000425
BSPBio_002302
C-5854
C07778
C21H25ClN2O3
C21H25ClN2O3.2HCl
C21H26Cl2N2O3
C21H27Cl3N2O3
CAS-83881-52-1
CC0153
CC0256
CCG-213404
Cetalerg
Ceterifug
Ceti TAD
Ceti-Puren
Cetiderm
Cetiderm (TN)
Cetidura
Cetil von ct
CetiLich
Cetirigamma
Cetirizin
Cetirizin AZU
Cetirizin Basics
Cetirizin dihydrochloride, >=98.0% (HPLC)
Cetirizina
Cetirizina [Spanish]
cetirizine
Cetirizine (dihydrochloride)
Cetirizine (INN)
Cetirizine [INN:BAN]
Cetirizine 2HCl
Cetirizine Di
Cetirizine diHCl
Cetirizine dihydrochloride
Cetirizine Dihydrochloride 1.0 mg/ml in Water (as free base)
Cetirizine dihydrochloride solution, 1.0 mg/mL in acetonitrile: water (9:1) (as free base), ampule of 1 mL, certified reference material
Cetirizine dihydrochloride, >=98% (HPLC)
Cetirizine dihydrochloride, European Pharmacopoeia (EP) Reference Standard
Cetirizine dihydrochloride, United States Pharmacopeia (USP) Reference Standard
Cetirizine for peak identification, European Pharmacopoeia (EP) Reference Standard
Cetirizine HCl
CETIRIZINE HYDROCHLORIDE
Cetirizine hydrochloride (JP17/USAN)
Cetirizine hydrochloride [USAN:USP]
Cetirizine hydrochloride [USAN]
Cetirizine Hydrochloride Allergy
Cetirizine Hydrochloride Hives
Cetirizine Hydrochloride, pharmaceutical secondary standard;traceable to USP, PhEur, BP
CETIRIZINE HYDROCHLORIDE/ CETIRIZINE DIHYDROCHLORIDE
cetirizinedihydrochloride
CetirizineHydrochloride
cetirizinhydrochlorid
Cetirizinum
Cetirizinum [Latin]
Cetirlan
Cetriler
Cetrine
Cetrizide
Cetrizine Dihcl
Cetrizine Hcl
Cetryn
Cetzine
Cezin
CHEBI:3561
CHEBI:3562
CHEMBL1000
CHEMBL1201113
CHEMBL1607273
Children's Cetirizine hydrochloride allergy
Children's Cetirizine hydrochloride hives relief
Children's Zyrtec
Children's Zyrtec Allergy
Children's Zyrtec Hives Relief
CPD001453715
CS-0886
CS-1798
CTK7J5576
CTK8B7912
CTK8C2999
CUSPGNDCPOVPBA-UHFFFAOYSA-N
D00664
D07662
D0DK8V
DB00341
DR002244
DSSTox_CID_24268
DSSTox_GSID_44268
DSSTox_RID_80138
DTXSID2044268
DTXSID4022787
EN300-52521
Formistin
FT-0603000
FT-0603001
FT-0654660
GTPL1222
HE180669
HE180670
HE180671
HE392232
HE395488
Hitrizin Film Tablet
HMS1539O07
HMS1569F07
HMS1922H04
HMS3259D06
HMS3370I19
HMS3393N10
HSDB 7739
HY-17042
HY-17042A
I06-0389
I06-0454
I14-0479
J-005737
J10151
KB-220360
KS-000015AD
KS-1042
L000655
LP00362
LS-11409
LS-11411
MCULE-8668839822
MFCD00800721
MFCD00941428
MLS000551288
MLS002222268
MolPort-000-832-941
MolPort-002-506-309
MolPort-003-939-603
NC00696
NCGC00016949-01
NCGC00095180-01
NCGC00095180-02
NCGC00167781-01
NCGC00167781-02
NCGC00167781-03
NCGC00167781-04
NCGC00167781-07
NCGC00255965-01
NCGC00261047-01
NCGC00263567-01
NSC-759102
NSC759102
P 071
P-071
PGLIUCLTXOYQMV-UHFFFAOYSA-N
Pharmakon1600-01505371
Prestwick_841
Prestwick0_000503
Prestwick1_000503
Prestwick2_000503
Prestwick3_000503
Reactine
Reactine (TN)
Ressital
Riztec
RT-007014
RTR-026026
Ryzen
s1291
Salvalerg
SAM002548972
SAM002589989
SBI-0206838.P001
SC-17992
SC-18167
SC-19204
SC-19390
SCHEMBL41107
SCHEMBL41108
SCHEMBL4176
Setir
Setiral
SMR000145214
SPBio_002346
SPECTRUM1505371
ST024755
ST077146
ST24039138
ST51051458
STK711108
STOCK2S-03020
Stopaler
Sun mark all day allergy
TC-147665
TimTec1_002075
Topcare all day allergy
Tox21_110704
Tox21_110704_1
Tox21_302261
Tox21_500362
Triz
U095
UCB-P 071
Up and up all day allergy relief
Virdos
Virlix
Voltric
Xero-sed
Z1182332250
Zetir
Ziptek
Zirtek
Zirtin
ZKLPARSLTMPFCP-UHFFFAOYSA-N
Zyrlex
Zyrtec
Zyrtec (TN)
Zyrtec Allergy
Zyrtec Hives Relief
Zyrtec Syrup
Zyrtec-D
Zyrzine

US Patents and Regulatory Information for ZERVIATE

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Eyevance Pharms ZERVIATE cetirizine hydrochloride SOLUTION/DROPS;OPHTHALMIC 208694-001 May 30, 2017 RX Yes Yes ➤ Sign Up ➤ Sign Up ➤ Sign Up
Eyevance Pharms ZERVIATE cetirizine hydrochloride SOLUTION/DROPS;OPHTHALMIC 208694-001 May 30, 2017 RX Yes Yes ➤ Sign Up ➤ Sign Up Y ➤ Sign Up
Eyevance Pharms ZERVIATE cetirizine hydrochloride SOLUTION/DROPS;OPHTHALMIC 208694-001 May 30, 2017 RX Yes Yes ➤ Sign Up ➤ Sign Up Y ➤ Sign Up
Eyevance Pharms ZERVIATE cetirizine hydrochloride SOLUTION/DROPS;OPHTHALMIC 208694-001 May 30, 2017 RX Yes Yes ➤ Sign Up ➤ Sign Up Y ➤ Sign Up
Eyevance Pharms ZERVIATE cetirizine hydrochloride SOLUTION/DROPS;OPHTHALMIC 208694-001 May 30, 2017 RX Yes Yes ➤ Sign Up ➤ Sign Up ➤ Sign Up
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration

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Supplementary Protection Certificates for ZERVIATE

Supplementary Protection Certificate SPC Country SPC Expiration SPC Description
00085 Netherlands ➤ Sign Up PRODUCT NAME: LEVOCETIRIZINE, DESGEWENST IN DE VORM VAN EEN FARMACEUTISCH AANVAARDBAAR ZOUT, IN HET BIJZONDER LEVOCETIRINE DIHYDROCHLORIDE; NAT. REGISTRATION NO/DATE: RVG 26770 20011009; FIRST REGISTRATION: DE 49903.00.00 AND 49904.00.00 20010103
01C/045 Belgium ➤ Sign Up PRODUCT NAME: DICHLORHYDRATE DE LEVOCETIRIZINE; NAT RER. NO/DATE: 194 IS 90 F3 20011022; FIRST REG.: DE 49903.00.00 20010103
Supplementary Protection Certificate SPC Country SPC Expiration SPC Description

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Serving hundreds of leading biopharmaceutical companies globally:

Teva
US Army
Fish and Richardson
AstraZeneca
Cantor Fitzgerald
Julphar
Deloitte
Farmers Insurance
Dow

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