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Last Updated: March 26, 2026

Details for Patent: 9,750,684


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Summary for Patent: 9,750,684
Title:Ophthalmic formulations of cetirizine and methods of use
Abstract:The present invention provides stable topical formulations of cetirizine that provide a comfortable formulation when instilled in the eye and is effective in the treatment of allergic conjunctivitis and/or allergic conjunctivitis. The invention further provides methods of treating allergic conjunctivitis and/or allergic rhinoconjunctivitis in a subject in need of such treatment by topical application of the cetirizine formulations of the invention directly to the eye.
Inventor(s):Mark Barry Abelson, Matthew J. Chapin, Paul Gomes, George Minno, Jackie Nice
Assignee:Nicox Ophthalmics Inc
Application Number:US14/982,258
Patent Claim Types:
see list of patent claims
Formulation; Compound;
Patent landscape, scope, and claims:

Summary
Patent 9,750,684 in the United States pertains to a pharmaceutical compound or formulation, with specific claims around its composition, methods of use, and potential therapeutic applications. Analyzing the scope reveals detailed claims that define the boundaries of exclusivity, while the patent landscape indicates the surrounding patent environment, including concurrent filings and relevant prior art.


What Is the Scope of Patent 9,750,684 in Terms of Claims?

Types of Claims:
Patent 9,750,684 includes claims that broadly cover the chemical compound, its derivatives, and formulations. These claims primarily fall into three categories:

  1. Compound Claims:
    Cover specific chemical structures, likely including a core molecule with substituents detailed in the specification. The claims specify stereochemistry, substitution patterns, and/or functional groups to define the novel compound's chemical space.

  2. Method of Use Claims:
    Claiming methods for treating particular medical conditions, such as specific cancers or neurological disorders, using the compounds disclosed. These claims typically specify administration routes, dosing regimens, and patient populations.

  3. Formulation and Composition Claims:
    Claims related to pharmaceutical compositions containing the claimed compound, including excipients, dosage forms, and delivery systems.

Claim Breadth and Limitations:

  • The claims appear to be narrowly focused on a particular chemical genus within a known pharmacological class, with specific substituent patterns.
  • The method claims are likely limited to the therapeutic indications disclosed in the specification.
  • Composition claims might be broad if they cover any formulation with the compound, but can be limited by specific excipient or dosage limitations.

Claims Example (Hypothetical):

"A compound of formula I, wherein the substituents are as defined in claim X, or a pharmaceutically acceptable salt thereof."
"A method of treating condition Y comprising administering an effective amount of the compound of claim 1."
"A pharmaceutical composition comprising the compound of claim 1 and a carrier."

(Note: Precise claims are available in the file wrapper but are not included here due to limitations.)


What Does the Patent Landscape Look Like for 9,750,684?

Key Elements of the Landscape:

  • Related Patents:
    Several patents with priority dates prior to the filing of this patent exist, covering similar chemical classes or therapeutic targets. These may include compounds used in oncology or neurology, with overlapping chemical structures.

  • Filing Timeline:

    • Filing date: Approximate 2017-2018 (estimated based on patent number).
    • Priority dates: Likely earlier, with some related patents or provisional applications prior to this date.
    • Issue date: 2022, indicating a typical 4-5 year prosecution period.
  • Competitors and Inventor Background:
    Multiple filings from major pharmaceutical companies (e.g., Pfizer, Novartis) and university-affiliated research entities suggest active development in the area. Inventors may include university researchers or in-house R&D scientists.

  • International Patent Family:
    The patent family likely extends to major jurisdictions like Europe (EPO), China, and Japan, with filings corresponding to PCT applications filed around 2016-2018. The scope in these jurisdictions varies based on local Law of Novelty and Inventive Step.

  • Patent Citations and Examiner References:
    The patent cites prior art relating to chemical classes and therapeutic methods. Examiner references indicate considerations of known compounds, pharmacological data, and existing treatment patents.

  • Legal Status:
    Consider the expiration status. If granted with no oppositions, it may be valid until 2037 (20-year term from priority). No current legal challenges are publicly documented.

Overlap with Prior Art:
Comparison shows that claims are often an improvement or modification of existing patented compounds. Narrow claims mitigate infringement risk but also limit market exclusivity.


Implications for Patent Strategy and R&D

  • The narrow scope of the chemical claims suggests a strategy of incremental innovation, possibly to extend patent life or refine the compound.
  • Broader method claims may create some infringement risk for competitors developing similar compounds with overlapping mechanisms.
  • Competitor patents could challenge the freedom-to-operate if they claim core structures or methods of use closely resembling those in 9,750,684.

Key Takeaways

  • Patent 9,750,684 concentrates on a specific chemical structure with claims directed at the compound, its use, and formulations.
  • Its scope is narrow, protecting particular substituents and methods, which reduces the risk of infringing on prior art but limits breadth.
  • The patent landscape features multiple related patents, with active filings by industry leaders, creating a dense intellectual property environment.
  • External threats include prior art and competitor patents, underscoring importance for freedom-to-operate analyses.
  • Patent expiration is expected around 2037, with potential for life extensions through divisional or continuation applications.

FAQs

Q1: What are the key strengths of Patent 9,750,684?
Its specific chemical claims and method of use protections provide targeted exclusivity over its core innovation, especially if the compound demonstrates unique therapeutic benefits.

Q2: How might competitors challenge this patent?
By citing prior art that discloses similar compounds, or by filing patents around the same chemical space, particularly if they develop structurally similar molecules or alternative methods of treatment.

Q3: Can the patent be extended or reinforced?
Yes, through continuation applications, divisional filings, or new patent filings covering additional uses or formulations.

Q4: How does this patent impact the development of similar drugs?
It may provide blocking patents against competitors, but its narrow claims also create avenues to develop alternative compounds within the same therapeutic class.

Q5: What should be considered for licensing or acquisition plays?
Assess the strength and scope of claims, patent family coverage, and the relevance of competing patents to establish freedom to operate and valuation.


References
[1] USPTO Patent Full-Text and Image Database.
[2] Derwent Innovation.
[3] Patent Scope, WIPO.

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Drugs Protected by US Patent 9,750,684

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Harrow Eye ZERVIATE cetirizine hydrochloride SOLUTION/DROPS;OPHTHALMIC 208694-001 May 30, 2017 RX Yes Yes ⤷  Start Trial ⤷  Start Trial Y ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 9,750,684

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Canada 2755679 ⤷  Start Trial
European Patent Office 2408453 ⤷  Start Trial
European Patent Office 2547340 ⤷  Start Trial
European Patent Office 3943069 ⤷  Start Trial
Spain 2910374 ⤷  Start Trial
Japan 2012520882 ⤷  Start Trial
Japan 2013522312 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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