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Serving hundreds of leading biopharmaceutical companies globally:

Colorcon
Queensland Health
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QuintilesIMS
UBS
Moodys
US Army
Deloitte
Chubb

Generated: April 22, 2018

DrugPatentWatch Database Preview

PERIOSTAT Drug Profile

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Which patents cover Periostat, and what generic alternatives are available?

Periostat is a drug marketed by Collagenex and Galderma Labs Lp and is included in two NDAs.

The generic ingredient in PERIOSTAT is doxycycline hyclate. There are twenty-seven drug master file entries for this compound. Eighty suppliers are listed for this compound. Additional details are available on the doxycycline hyclate profile page.
Drug patent expirations by year for PERIOSTAT
Synonyms for PERIOSTAT
(2E,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione
(2E,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione; ethanol; hydrate; dihydrochloride
(2Z,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione; ethanol; hydrate; dihydrochloride
(2Z,4S,4AR,5S,5AR,6R,12AS)-2-[AMINO(HYDROXY)METHYLIDENE]-4-(DIMETHYLAMINO)-5,10,11,12A-TETRAHYDROXY-6-METHYL-1,2,3,4,4A,5,5A,6,12,12A-DECAHYDROTETRACENE-1,3,12-TRIONE
(2Z,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione
(2Z,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione; ethanol; hydrate; dihydrochloride
(2Z,4S,4aR,5S,5aR,6R)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione
(2Z)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione
(4S,4aR,5S,5aR,6R,12aR)-4-(dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide
(4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione
(4s,4ar,5s,5ar,6r,12as)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide
(4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
(4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide - ethanol (2:1) dihydrochloride hydrate
(4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide compound with ethanol (2:1) dihydrochloride hydrate
(4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide
(4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide;ethanol;hydrate;dihydrochloride
10592-13-9
10592-13-9 (. HCl)
10597-92-9
1368-EP2269978A2
1368-EP2269985A2
1368-EP2269991A2
1368-EP2284150A2
1368-EP2284151A2
1368-EP2284152A2
1368-EP2284153A2
1368-EP2284155A2
1368-EP2284156A2
1368-EP2284164A2
1368-EP2287140A2
1368-EP2287148A2
1368-EP2287150A2
1368-EP2289871A1
1368-EP2295402A2
1368-EP2295419A2
1368-EP2298732A1
1368-EP2301534A1
1368-EP2301912A2
1368-EP2301913A1
1368-EP2301914A1
1368-EP2301916A2
1368-EP2305637A2
1368-EP2305640A2
1368-EP2308863A1
1368-EP2311451A1
1368-EP2311796A1
1368-EP2311797A1
1368-EP2311798A1
1368-EP2311799A1
1368-EP2316450A1
17086-28-1 (mono-hydrate)
19XTS3T51U
2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a, 5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy -6-methyl-1,11-dioxo-, monohydrochloride, (4S,4aR,5S,5aR,6R,12aS)-, compd. with ethanol (2:1), mono
2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S-(4alpha,4aalpha,5alpha,5aalpha,6alpha,12aalpha))-
2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S,4aR,5S,5aR,6R,12aS)
2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S,4aR,5S,5aR,6R,12aS)-
2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride, (4S,4aR,5S,5aR,6R,12aS)-, compd. with ethanol, hydrate (2:2:1:1)
2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, compd. with ethanol (2:1), monohydrate, (4S-(4alpha,4aalpha,5alpha,5aalpha,6alpha,
2-Naphthacenecarboxamide, 4-alpha-S-(dimethylamino)-1,4,4a-alpha-5,5a-alpha,6,11,12a-octahydro-3,5-alpha,10,12,12a-alpha-pentahydroxy-6-alpha-methyl-1,11-dioxo-
2-Naphthacenecarboxamide, 4beta-(dimeethylamino)-1,4,4abeta,5,5abeta,6,11,12a-octahydro-3,5beta,10,12,12abeta-pentahydroxy-6beta-methyl-1,11-dioxo-, monohydrochloride, compd. with ethyl alcohol (2:1), monohydrate
2387AH
24390-14-5
2C22H24N2O8.C2H6O.2ClH.H2O
2C22H24N2O8.C2H6O.H2O
334895S862
4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide monohydrochloride, compound with ethyl alcohol (2:1), monohydrate
4-Epioxytetracycline, 6-deoxy-
41411-66-9 (6-epimer, mono-hydrochloride)
5-Hydroxy-alpha-6-deoxytetracycline
5-Hydroxy-alpha-6-deoxytetracycline monohydrate
564-25-0
564D250
6-alpha-Deoxy-5-oxytetracycline
6-Deoxy-5-hydroxytetracycline hydrochloride hemihydrate
6-Deoxyoxytetracycline
6-Deoxytetracycline
62149-53-5
69935-17-7 (mono-hydrochloride, di-hydrate)
6alpha-Deoxy-5-oxytetracycline
7164-70-7
7264-10-0
94088-85-4 (calcium salt (1:2))
AB00053465_04
AB00053465_05
AB00053465-03
AB08 (*Fosfatex)
AC1L1WYQ
AC1NQXW7
AC1NQZPV
AC1NUYS5
AC1NUYS8
Acticlate
Acticlate CAP
AK322076
AKOS015900372
alpha-6-Deoxy-5-hydroxytetracycline
alpha-6-Deoxyoxytetracycline
alpha-6-Deoxyoxytetracycline monohydrate
alpha-6-Tetracycline monohydrate
alpha-Doxycycline
Alti-Doxycycline
AN-18097
Anhydrous doxycycline
API0002491
Apo-Doxy
AS-13499
Atridox
Azudoxat
BCBcMAP01_000024
bis((4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide) ethanol hydrate dihydrochloride
BMY 28689
BMY-28689
BMY28689
BSPBio_001936
BU 3839T
BU-3839T
C06973
CCG-204498
CHEBI:50845
CHEMBL1433
CHEMBL436921
controlled-release doxycycline hy-clate
D02129
D07876
D0S0LZ
DB00254
Dentista
Deoxymykoin
DivK1c_000345
DMSC (*Fosfatex)
Doryx
Doryx (TN)
Doryx Mpc
Dossiciclina
Dossiciclina [DCIT]
DOXCYCLINE ANHYDROUS
Doxiciclina
Doxiciclina [INN-Spanish]
Doxiciclina [Italian]
Doxitard
Doxivetin
Doxteric
DOXY
Doxy 100
DOXY 200
Doxy-Caps
Doxy-Lemmon
Doxy-Puren
Doxy-Tabs
Doxycen
Doxychel
Doxychel (TN)
Doxychel Hyclate
Doxycin
Doxycyclin
doxycycline
Doxycycline (200mg/day) or Placebo
Doxycycline (anhydrous)
Doxycycline (INN)
Doxycycline (internal use)
Doxycycline (TN)
Doxycycline [USAN:INN:BAN]
Doxycycline anhydrous
DOXYCYCLINE CALCIUM
Doxycycline HCl
Doxycycline hyclate
Doxycycline Hyclate (100 mg)
Doxycycline hyclate (internal use)
Doxycycline hyclate (USP)
Doxycycline hyclate [USAN:USP]
doxycycline hyclate 20 mg twice daily
Doxycycline hydrochloride
Doxycycline hydrochloride hemiethanolate hemihydrate
Doxycycline hydrochloride hydrate (JP17)
DOXYCYCLINE HYLATE
Doxycycline-Chinoin
Doxycycline, Antibiotic for Culture Media Use Only
Doxycyclinum
Doxycyclinum [INN-Latin]
Doxylin
Doxyprex
Doxysol
Doxytec
Doxytetracycline
DTXSID0037653
DTXSID4041020
EINECS 209-271-1
Ethanol, compd. with (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide monohydrochloride (1:2), monohydrate
FT-0603476
GS-3065
GS-3065 (*monohydrate)
GTPL6464
HMS2090E06
HSDB 3071
Hydramycin
I455
IDI1_000345
Investin
JBIWCJUYHHGXTC-AKNGSSGZSA-N
Jenacyclin
KBio1_000345
KBio2_001287
KBio2_003855
KBio2_006423
KBio3_001156
KBioGR_001133
KBioSS_001287
Liviatin
LMPK07000001
Lopac0_000405
LS-174052
LS-187766
LS-93868
MCULE-4368118692
MFCD07357237
MMV000011
MolPort-002-507-423
MolPort-005-932-536
MolPort-039-338-208
MolPort-042-652-606
Monodoks
Monodox
Monodox (*monohydrate)
NCGC00161602-01
NCGC00161602-03
NCGC00161602-04
NCGC00161602-05
NCGC00188979-01
NINDS_000345
Novo-Doxylin
NSC633557
Nu-Doxycycline
Oracea
Oxytetracycline, 6-deoxy-
Periostat (TN)
PL000396
PL040705
Ronaxan
Roximycin
RPRXAHFLWOCXQL-AKNGSSGZSA-N
SBI-0050391.P004
SC-15766
SCHEMBL17826665
SCHEMBL19270298
SCHEMBL40930
SCHEMBL66828
SGKRLCUYIXIAHR-AKNGSSGZSA-N
SMP1_000107
Spanor
SPBio_000246
Spectrum_000807
Spectrum2_000143
Spectrum3_000408
Spectrum4_000527
Spectrum5_000947
SR-01000075844
SR-01000075844-7
STOCK1N-34341
Supracyclin
Tetraclean
UNII-19XTS3T51U
UNII-334895S862
UPCMLD-DP021
UPCMLD-DP021:001
Vibra-tabs
Vibra-tabs (TN)
Vibramycin
Vibramycin (*monohydrate)
Vibramycin hyclate
Vibramycin Novum
Vibramycine
Vibravenos
Vivox
Vivox (*Hyclate)
W-105517
WC 2031
Z2791720087
Zenavod
ZINC100056779
ZINC100302137
ZINC100611210
ZINC109562088
ZINC16052277

US Patents and Regulatory Information for PERIOSTAT

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Collagenex PERIOSTAT doxycycline hyclate CAPSULE;ORAL 050744-001 Sep 30, 1998 DISCN Yes No ➤ Sign Up ➤ Sign Up ➤ Sign Up
Galderma Labs Lp PERIOSTAT doxycycline hyclate TABLET;ORAL 050783-001 Feb 2, 2001 DISCN Yes No ➤ Sign Up ➤ Sign Up ➤ Sign Up
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Harvard Business School
UBS
Cerilliant
Teva
Healthtrust
Moodys
Dow
Daiichi Sankyo
McKinsey

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.