You're using a free limited version of DrugPatentWatch: ➤ Start for $299 All access. No Commitment.

Last Updated: December 12, 2025

PERIOGARD Drug Patent Profile


✉ Email this page to a colleague

« Back to Dashboard


AI Deep Research
Questions you can ask:
  • What is the 5 year forecast for PERIOGARD?
  • What are the global sales for PERIOGARD?
  • What is Average Wholesale Price for PERIOGARD?
Drug patent expirations by year for PERIOGARD
Drug Prices for PERIOGARD

See drug prices for PERIOGARD

Drug Sales Revenue Trends for PERIOGARD

See drug sales revenues for PERIOGARD

Recent Clinical Trials for PERIOGARD

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
Colgate PalmolivePHASE3
Colgate PalmolivePhase 2
University of North Carolina, Chapel HillPhase 2

See all PERIOGARD clinical trials

Pharmacology for PERIOGARD
Physiological EffectDecreased Cell Wall Integrity

US Patents and Regulatory Information for PERIOGARD

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Colgate Palmolive Co PERIOGARD chlorhexidine gluconate SOLUTION;DENTAL 073695-001 Jan 14, 1994 DISCN No No ⤷  Get Started Free ⤷  Get Started Free ⤷  Get Started Free
Colgate-palmolive Co PERIOGARD chlorhexidine gluconate SOLUTION;DENTAL 203212-001 Jan 28, 2016 AT RX No No ⤷  Get Started Free ⤷  Get Started Free ⤷  Get Started Free
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

Market Dynamics and Financial Trajectory for PERIOGARD

Last updated: August 5, 2025


Introduction

PERIOGARD, a well-established antiseptic mouth rinse primarily used in periodontal therapy, has long occupied a significant niche in oral healthcare. Its active ingredient, chlorhexidine gluconate, is recognized for its antimicrobial efficacy and substantial role in controlling periodontal infections. As the dental and broader healthcare markets evolve, understanding the market dynamics and financial trajectory of PERIOGARD offers invaluable insights for industry stakeholders, including manufacturers, investors, and healthcare providers.


Market Overview and Key Drivers

1. Growing Prevalence of Periodontal Diseases

Global epidemiological data indicates an increasing prevalence of periodontal diseases, attributed to aging populations, lifestyle factors, and tobacco use. According to the World Health Organization (WHO), severe periodontal disease affects nearly 10-15% of the global adult population, driving demand for adjunctive therapies like antiseptic mouth rinses (WHO, 2018). This trend enhances the demand for products like PERIOGARD, especially in dental clinics and periodontics practices.

2. Rise in Prevention and Oral Hygiene Awareness

Enhanced awareness regarding oral health's systemic impact fuels consumer demand for preventative measures. Dental practices emphasize the use of antiseptic rinses post-scaling and root planing, positioning PERIOGARD as a preferred choice due to its proven efficacy. Public health campaigns and the proliferation of dental care education further propel market growth.

3. Regulatory and Clinical Endorsements

Regulatory approvals and endorsements from dental associations bolster market confidence. PERIOGARD has received recognition from organizations such as the American Dental Association (ADA), incentivizing practitioners to incorporate it into standard periodontal care.

4. Competitive Landscape and Market Share

While chlorhexidine-based products dominate, competition from herbal and alternative rinse formulations persists. However, PERIOGARD’s longstanding clinical validation maintains a competitive edge, shaping its market share stability.


Market Challenges and Constraints

1. Side Effect Profile and Usage Limitations

Prolonged use of chlorhexidine rinses like PERIOGARD can lead to adverse effects, including tooth staining, taste disturbances, and mucosal irritation. These limitations restrict long-term usage, impacting repeat sales and necessitating development of formulations with improved tolerability.

2. Resistance and Antimicrobial Stewardship

Antimicrobial resistance concerns influence prescribing behaviors, underscoring the need for judicious use. The shift towards individualized, minimally invasive periodontal treatment may marginalize antiseptic rinses in favor of mechanical debridement alone in some contexts.

3. Market Saturation and Innovation Needs

The mature nature of the market demands continuous innovation to sustain growth, including formulation enhancements or adjunctive delivery systems to mitigate side effects and enhance patient compliance.


Financial Trajectory and Revenue Streams

1. Revenue Sources

PERIOGARD's revenue streams encompass direct sales to dental practices, institutional procurement, and consumer retail channels. The product’s integration into periodontal therapy protocols ensures steady demand, especially in clinical settings.

2. Pricing Strategies and Profit Margins

Premium pricing persists due to brand recognition and clinical endorsement. Despite competitive pressures, companies often leverage patent protections, exclusive formulations, and bundled dental care packages to optimize margins.

3. Impact of Market Trends on Financial Performance

Market growth rates for chlorhexidine-based rinses are projected around 3-5% annually over the next five years (Market Research Future, 2022). The stabilization of market share for PERIOGARD, combined with expanding dental markets in emerging economies, could yield incremental revenue growth.

4. Potential for Diversification and Expansion

Companies may explore extending PERIOGARD’s line to include products with reduced side effects, such as formulations with lower chlorhexidine concentrations or combined therapeutics. Entry into adjacent markets, like oral antiseptic sprays or gels, can diversify income streams.


Future Outlook and Strategic Implications

1. Innovation and Product Development

Investing in formulation innovation to diminish side effects and enhance patient compliance will be critical. Combining chlorhexidine with novel bioactive agents may rejuvenate interest and usage frequency.

2. Market Expansion in Emerging Economies

Expanding distribution in Asia-Pacific, Latin America, and Africa offers significant growth potential given rising oral health awareness and improving healthcare infrastructure.

3. Competitive Differentiation

Maintaining a technological edge through clinical evidence, regulatory approvals, and patient-centric formulations will bolster PERIOGARD’s market standing amidst fierce competition.

4. Regulatory and Reimbursement Developments

Anticipated shifts towards stricter antimicrobial stewardship policies will influence formulary inclusion and reimbursement rates. Early engagement with regulatory bodies enhances market access prospects.


Key Takeaways

  • The global rise in periodontal disease prevalence and heightened oral health awareness underpin PERIOGARD’s sustained market relevance.
  • Competitive advantages hinge on clinical validation, regulatory endorsements, and innovation to address side effects.
  • Revenue stabilization is achievable through targeted expansion in emerging markets and diversification of product formats.
  • Challenges like antimicrobial resistance and product side effects necessitate strategic R&D investments.
  • Future growth hinges on leveraging innovation, expanding reach in developing economies, and aligning with evolving healthcare policies.

FAQs

1. What factors contribute to PERIOGARD’s market stability?
PERIOGARD’s established clinical efficacy, regulatory endorsements, and integration into standard periodontal protocols underpin its stability amidst market fluctuations.

2. How do side effects impact PERIOGARD’s sales?
While side effects such as staining and taste disturbances limit long-term use, targeted patient education and formulation improvements help mitigate impact on sales.

3. What is the growth outlook for chlorhexidine-based rinses?
Projected growth remains modest (~3-5% annually), driven by increasing periodontal disease prevalence and expanding dental markets.

4. Which regions present the most growth opportunities for PERIOGARD?
Emerging economies in Asia-Pacific, Latin America, and Africa offer significant expansion potential due to rising oral health awareness and healthcare infrastructure development.

5. How can companies sustain revenue growth for PERIOGARD?
By investing in formulation innovations, expanding into new markets, and developing complementary oral care products, companies can sustain revenue momentum.


References

  1. WHO. (2018). Global Oral Health Status Report. World Health Organization.
  2. Market Research Future. (2022). Oral Care Market - Forecast to 2027.

Note: All data and projections are based on publicly available market research reports and industry analyses as of 2023.

More… ↓

⤷  Get Started Free

Make Better Decisions: Try a trial or see plans & pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. We do not provide individual investment advice. This service is not registered with any financial regulatory agency. The information we publish is educational only and based on our opinions plus our models. By using DrugPatentWatch you acknowledge that we do not provide personalized recommendations or advice. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.