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Generated: May 23, 2019

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OPTISON Drug Profile

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Which patents cover Optison, and when can generic versions of Optison launch?

Optison is a drug marketed by Ge Healthcare and is included in one NDA. There is one patent protecting this drug.

This drug has forty patent family members in twenty-seven countries.

The generic ingredient in OPTISON is albumin human. There are seven drug master file entries for this compound. One supplier is listed for this compound. Additional details are available on the albumin human profile page.

Drug patent expirations by year for OPTISON
Generic Entry Opportunity Date for OPTISON
Generic Entry Date for OPTISON*:
Constraining patent/regulatory exclusivity:
NDA:
Dosage:
INJECTABLE;INJECTION

*The generic entry opportunity date is the latter of the last compound-claiming patent and the last regulatory exclusivity protection. Many factors can influence early or later generic entry. This date is provided as a rough estimate of generic entry potential and should not be used as an independent source.

Pharmacology for OPTISON
Synonyms for OPTISON
1,1,1,2,2,3,3,3-Octafluoropropane
1,1,1,2,2,3,3,3-octakis(fluoranyl)propane
218599-63-4
300408-51-9
76-19-7
A838638
AC1L1MIR
AC1Q4IBX
AKOS006228213
AN-23892
AN-37829
C-50894
C3F8
C3F8-gas
CHEBI:31980
CHEMBL1663
CK0N3WH0SR
CTK5E2580
D01738
DB-056033
DB00556
Definity
Definity (TN)
DMP 115
DMP-115
DTXSID9052503
EC 200-941-9
EINECS 200-941-9
FC 218
FC 218 (refrigerant)
FCH918400
Flutec PP30
Freon 218
FS-069
FS069
FT-0621948
FT-0631321
Genetron 218
HFC 218
HSDB 8074
I14-14876
KB-59511
liposome-encapsulated perfluoropane microsphere
LS-120891
MRX 115
MRX-115
OCTAFLUOROPROPANE
octafluoropropane-lipid microsphere
Octafluoropropaneor Refrigerant gas R 218
Octafluoropropaneor Refrigerant gas R 218 [UN2424] [Nonflammable gas]
Octafluoropropaneor Refrigerant gas R 218 [UN2424] [Nonflammable gas]
Octafluorpropan
Oktafluorpropan
Optison (Salt/Mix)
Perfluoropropane
Perfluoropropane (PFC-218) 99.9%
Perfluoropropane 99+%
Perfluoropropaneminimum
Perflutren
Perflutren (JAN/USAN/INN)
Perflutren [USAN:INN:BAN]
Perflutren [USAN]
Perflutren and Human Albumin
Perflutren Lipid Microsphere
Perflutren lipid microspheres
Perflutren Protein-Type A Microspheres injection
Perflutren-lipid microsphere
PFC 218
Propane, 1,1,1,2,2,3,3,3-octafluoro-
Propane, octafluoro-
Propane,1,1,1,2,2,3,3,3-octafluoro-
QYSGYZVSCZSLHT-UHFFFAOYSA-N
R 218
RC 218, PFC 218
SBB090673
UN 2424
UN2424
UNII-CK0N3WH0SR
YM454
ZINC8214651
ZX-AP010865

US Patents and Regulatory Information for OPTISON

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Ge Healthcare OPTISON albumin human INJECTABLE;INJECTION 020899-001 Dec 31, 1997 RX Yes Yes ➤ Try a Free Trial ➤ Try a Free Trial Y ➤ Try a Free Trial
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration

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Expired US Patents for OPTISON

Applicant Tradename Generic Name Dosage NDA Approval Date Patent No. Patent Expiration
Ge Healthcare OPTISON albumin human INJECTABLE;INJECTION 020899-001 Dec 31, 1997 ➤ Try a Free Trial ➤ Try a Free Trial
Ge Healthcare OPTISON albumin human INJECTABLE;INJECTION 020899-001 Dec 31, 1997 ➤ Try a Free Trial ➤ Try a Free Trial
Ge Healthcare OPTISON albumin human INJECTABLE;INJECTION 020899-001 Dec 31, 1997 ➤ Try a Free Trial ➤ Try a Free Trial
Applicant Tradename Generic Name Dosage NDA Approval Date Patent No. Patent Expiration

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Supplementary Protection Certificates for OPTISON

Patent Number Supplementary Protection Certificate SPC Country SPC Expiration SPC Description
0961612 2009C/046 Belgium ➤ Try a Free Trial PRODUCT NAME: PACLITAXEL ALBUMIN; AUTHORISATION NUMBER AND DATE: EU/1/07/428/001 20080111
0961612 C00961612/01 Switzerland ➤ Try a Free Trial PRODUCT NAME: PACLITAXELUM-ALBUMINUM; REGISTRATION NO/DATE: SWISSMEDIC 63182 26.08.2014
1853250 37/2014 Austria ➤ Try a Free Trial PRODUCT NAME: PACLITAXEL, DAS ALS ALBUMIN GEBUNDENE NANOPARTIKEL FORMUIERT IST.; REGISTRATION NO/DATE: EU/1/07/428 (MITTEILUNG) (GEAENDERT DURCH C(2013) 9835) 20131230
0961612 09C0050 France ➤ Try a Free Trial PRODUCT NAME: PACLITAXEL ALBUMINE; REGISTRATION NO/DATE: EU/1/07/428/001 20080111
1853250 238 50005-2014 Slovakia ➤ Try a Free Trial PRODUCT NAME: PAKLITAXEL VO FORME NANOCASTIC VIAZANYCH NA ALBUMIN; REGISTRATION NO/DATE: EU/1/07/428/001 - EU/1/07/428/002 20131230
1853250 C300673 Netherlands ➤ Try a Free Trial PRODUCT NAME: PACLITAXEL, GEFORMULEERD ALS ALBUMINE-GEBONDEN NANODEELTJES; REGISTRATION NO/DATE: EU/1/07/428/001-002 20131220
0961612 CA 2009 00036 Denmark ➤ Try a Free Trial PRODUCT NAME: PACLITAXELALBUMIN
Patent Number Supplementary Protection Certificate SPC Country SPC Expiration SPC Description

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