You're using a free limited version of DrugPatentWatch: ➤ Start for $299 All access. No Commitment.

Last Updated: March 29, 2026

MOTRIN MIGRAINE PAIN Drug Patent Profile


✉ Email this page to a colleague

« Back to Dashboard


Which patents cover Motrin Migraine Pain, and what generic alternatives are available?

Motrin Migraine Pain is a drug marketed by Kenvue Brands and is included in one NDA.

The generic ingredient in MOTRIN MIGRAINE PAIN is ibuprofen. There are sixty-four drug master file entries for this compound. Two hundred and forty-one suppliers are listed for this compound. Additional details are available on the ibuprofen profile page.

DrugPatentWatch® Litigation and Generic Entry Outlook for Motrin Migraine Pain

A generic version of MOTRIN MIGRAINE PAIN was approved as ibuprofen by CONTRACT PHARMACAL on October 15th, 1986.

  Start Trial

AI Deep Research
Questions you can ask:
  • What is the 5 year forecast for MOTRIN MIGRAINE PAIN?
  • What are the global sales for MOTRIN MIGRAINE PAIN?
  • What is Average Wholesale Price for MOTRIN MIGRAINE PAIN?
Drug patent expirations by year for MOTRIN MIGRAINE PAIN
Recent Clinical Trials for MOTRIN MIGRAINE PAIN

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
Oregon Health and Science UniversityPhase 2/Phase 3

See all MOTRIN MIGRAINE PAIN clinical trials

Pharmacology for MOTRIN MIGRAINE PAIN

US Patents and Regulatory Information for MOTRIN MIGRAINE PAIN

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Kenvue Brands MOTRIN MIGRAINE PAIN ibuprofen TABLET;ORAL 019012-004 Feb 25, 2000 DISCN No No ⤷  Start Trial ⤷  Start Trial ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

EU/EMA Drug Approvals for MOTRIN MIGRAINE PAIN

Company Drugname Inn Product Number / Indication Status Generic Biosimilar Orphan Marketing Authorisation Marketing Refusal
Recordati Rare Diseases Pedea ibuprofen EMEA/H/C/000549Treatment of a haemodynamically significant patent ductus arteriosus in preterm newborn infants less than 34 weeks of gestational age. Authorised no no no 2004-07-28
>Company >Drugname >Inn >Product Number / Indication >Status >Generic >Biosimilar >Orphan >Marketing Authorisation >Marketing Refusal

MOTRIN MIGRAINE PAIN Market Analysis and Financial Projection

Last updated: February 10, 2026

Market Dynamics and Financial Trajectory of Motrin Migraine Pain

Market Size and Growth

The global analgesics market, which includes medications for migraine pain relief, is valued at approximately $9.2 billion in 2022. It is projected to grow at a compound annual growth rate (CAGR) of 4.2% through 2030, driven by rising migraine prevalence, especially in younger populations and women of reproductive age.

Specifically, the migraine segment of the analgesics market accounts for roughly 30%. Within this, OTC options like Motrin Migraine Pain rank highly for consumer preference due to familiarity, OTC availability, and affordability. The OTC migraine medication segment is estimated at $2.3 billion in 2022 and forecast to grow to over $3 billion by 2030.

Competitive Landscape

Motrin Migraine Pain, based on ibuprofen, is positioned as an over-the-counter NSAID (non-steroidal anti-inflammatory drug). It competes with products such as:

  • Excedrin Migraine (acetaminophen, aspirin, caffeine)
  • Tylenol Migraine (acetaminophen)
  • Aleve (naproxen)

Key differentiators include:

  • Broad availability across pharmacies, supermarkets, and online platforms
  • Established brand recognition
  • Lower price point relative to combination therapies

The market faces competition from prescription migraine-specific drugs, such as triptans and CGRP inhibitors, which target more severe or chronic cases.

Regulatory and Patent Status

Motrin Migraine Pain formulations are over-the-counter, with FDA approval for momentary relief of migraine pain. The original patent for generic ibuprofen expired in the early 2000s, allowing multiple manufacturers to produce generic versions. No recent patent protections are in place, increasing market entry of generics and brand equivalents, which exert downward pressure on prices.

Innovations or reformulations are unlikely to significantly extend patent exclusivity, given the generic landscape.

Consumer Trends and Market Drivers

The key drivers for Motrin Migraine Pain include:

  • Increasing awareness of OTC options for migraine management
  • Growing migraine prevalence, affecting approximately 1 billion people globally (WHO)
  • Preference for low-cost, accessible treatments
  • Expansion of e-commerce channels facilitating direct-to-consumer sales

Healthcare providers often advise OTC NSAIDs for mild to moderate migraine attacks, which sustains demand.

Revenue and Market Share Trajectory

No public detailed revenue data exists for Motrin Migraine Pain alone. However, as an OTC product, its sales volume correlates with the broader NSAID OTC market.

Assuming an average retail price point of approximately $7-$10 per package and monthly consumption in active migraine sufferers, we estimate:

  • Annual retail sales of Motrin Migraine Pain could approximate $100-$250 million in the U.S., considering market penetration and consumer usage patterns.

Growth prospects are linked to increased migraine diagnosis rates and consumer preference shifts toward OTC therapies. A conservative CAGR of 3-4% reflects ongoing market stability and gradual expansion.

Pricing and Reimbursement Factors

Since Motrin Migraine Pain is OTC, reimbursement policies do not directly influence sales. Pricing is dictated by manufacturers, pharmacy retailers, and competitive positioning.

Price sensitivity among consumers favors low-cost, effective OTC options, with little room for premium pricing unless reformulated with added benefits.

Financial Outlook

Given the mature status of ibuprofen-based OTC formulations, significant revenue increases hinge on:

  • Market expansion into emerging markets where OTC analgesic use is rising
  • Product line extensions with formulations targeting specific sub-populations
  • Strategic marketing to maintain or grow market share

The overall financial trajectory remains stable with modest growth potential unless new, differentiated formulations or therapy delivery mechanisms are introduced.

Regulatory Challenges and Future Opportunities

Emerging regulatory considerations include limits on NSAID dosage due to gastrointestinal and cardiovascular risk profiles. These could impact sales volume if restrictions tighten.

Future opportunities involve digital health integrations, such as smart packaging or companion apps to support migraine management, representing potential value-added features.

Key Takeaways

  • The global OTC migraine relief market is approximately $2.3 billion in 2022, with steady growth driven by increased migraine prevalence and demand for accessible treatments.
  • Motrin Migraine Pain faces competition from both OTC and prescription therapies; its market position benefits from affordability and brand recognition.
  • Patent expirations for ibuprofen have increased generic competition; innovation avenues are limited due to the drug’s patent status.
  • Sales are primarily driven by consumer preference for cost-effective OTC options, with growth expected at a CAGR of 3-4%.
  • Future growth depends on expanding into emerging markets, product differentiation, and potentially leveraging digital health solutions.

FAQs

1. What is the primary market for Motrin Migraine Pain?
The primary market is the OTC analgesics segment, targeting consumers seeking immediate relief for mild to moderate migraine attacks in North America and Europe.

2. How does generic competition impact Motrin Migraine Pain’s profitability?
Generic ibuprofen formulations reduce pricing power and market share for brand-name products, exerting downward pressure on revenues.

3. Are there regulatory risks for OTC ibuprofen products?
Yes. Increasing safety regulations may lead to dosage restrictions or label changes that could influence sales volume.

4. What growth strategies could extend Motrin Migraine Pain’s market share?
Strategies include geographic expansion, product reformulation targeting specific demographics, and integrating digital health engagement tools.

5. How does consumer behavior influence the OTC migraine medication market?
Consumers favor affordable, readily accessible options with proven efficacy. Mounting migraine prevalence sustains demand for OTC relief options like Motrin Migraine Pain.


Citations

[1] Market Data Forecasts, "Analgesics Market Size & Growth," 2022.
[2] World Health Organization, "Migraine Fact Sheet," 2022.
[3] IBISWorld, "Over-the-Counter (OTC) Drug Industry Analysis," 2022.
[4] FDA, "Over-the-Counter Drugs: Regulations and Safety," 2022.

More… ↓

⤷  Start Trial

Make Better Decisions: Try a trial or see plans & pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. We do not provide individual investment advice. This service is not registered with any financial regulatory agency. The information we publish is educational only and based on our opinions plus our models. By using DrugPatentWatch you acknowledge that we do not provide personalized recommendations or advice. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.