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Last Updated: December 18, 2025

MOTRIN MIGRAINE PAIN Drug Patent Profile


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Which patents cover Motrin Migraine Pain, and what generic alternatives are available?

Motrin Migraine Pain is a drug marketed by Kenvue Brands and is included in one NDA.

The generic ingredient in MOTRIN MIGRAINE PAIN is ibuprofen. There are sixty-four drug master file entries for this compound. Two hundred and forty-five suppliers are listed for this compound. Additional details are available on the ibuprofen profile page.

DrugPatentWatch® Litigation and Generic Entry Outlook for Motrin Migraine Pain

A generic version of MOTRIN MIGRAINE PAIN was approved as ibuprofen by STRIDES PHARMA INTL on September 24th, 1986.

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Drug patent expirations by year for MOTRIN MIGRAINE PAIN
Recent Clinical Trials for MOTRIN MIGRAINE PAIN

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Oregon Health and Science UniversityPhase 2/Phase 3

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Pharmacology for MOTRIN MIGRAINE PAIN

US Patents and Regulatory Information for MOTRIN MIGRAINE PAIN

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Kenvue Brands MOTRIN MIGRAINE PAIN ibuprofen TABLET;ORAL 019012-004 Feb 25, 2000 DISCN No No ⤷  Get Started Free ⤷  Get Started Free ⤷  Get Started Free
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

EU/EMA Drug Approvals for MOTRIN MIGRAINE PAIN

Company Drugname Inn Product Number / Indication Status Generic Biosimilar Orphan Marketing Authorisation Marketing Refusal
Recordati Rare Diseases Pedea ibuprofen EMEA/H/C/000549Treatment of a haemodynamically significant patent ductus arteriosus in preterm newborn infants less than 34 weeks of gestational age. Authorised no no no 2004-07-28
>Company >Drugname >Inn >Product Number / Indication >Status >Generic >Biosimilar >Orphan >Marketing Authorisation >Marketing Refusal

Market Dynamics and Financial Trajectory for MOTRIN MIGRAINE PAIN

Last updated: July 29, 2025


Introduction

MOTRIN MIGRAINE PAIN represents a specialized segment within the broader analgesic market, leveraging its established brand recognition and active ingredient, ibuprofen, to cater specifically to migraine sufferers. As migraine prevalence increases globally, driven by lifestyle factors and heightened awareness, the demand for targeted, over-the-counter (OTC) solutions such as MOTRIN MIGRAINE PAIN continues to grow. This article explores the evolving market dynamics, competitive landscape, regulatory influences, and financial trajectory influencing this product’s future.


Market Overview and Consumer Trends

Global Migraine Burden

Migraine affects over 1 billion individuals globally, with prevalence rates rising annually (source: WHO). The condition significantly impairs productivity, with direct and indirect economic costs estimated in the hundreds of billions annually. The US, Europe, and emerging markets witness substantial growth in demand for effective, rapid-onset OTC treatments. Consumer preference shifts toward pain relief products with established safety profiles further solidify MOTRIN MIGRAINE PAIN’s market position.

Consumer Preferences and Behavior

Modern consumers prioritize fast-acting relief, minimal side effects, and brand reliability. The trend towards self-medication and OTC access drives increased sales of migraine-specific analgesics. The branding of MOTRIN MIGRAINE PAIN aligns with consumer expectations for immediate relief, leveraging the trusted MOTRIN brand and its reputation for safety and efficacy.


Market Dynamics

Competitive Landscape

Key Competitors:

  • Excedrin Migraine (GSK)
  • Advil Migraine (Pfizer)
  • Generic ibuprofen brands
  • New entrants offering combination therapies or alternative formulations

Strategic Position:
MOTRIN MIGRAINE PAIN’s strength lies in brand loyalty, extensive distribution channels, and consumer trust. However, increasing competition from both branded and generic formulations exerts pricing pressure and hampers market share expansion.

Regulatory Environment

Regulatory agencies, notably the FDA (Food and Drug Administration) and EMA (European Medicines Agency), enforce rigorous standards for OTC analgesics. Recent updates focus on labeling clarity, packaging, and post-market surveillance to ensure safety, particularly for populations with comorbid conditions or specific age groups. The regulatory environment influences product reformulation, marketing strategies, and permissible claims, directly impacting financial projections.

Innovation and Formulation Trends

The market witnesses accelerated innovation, including:

  • Combination products integrating caffeine or other analgesics for enhanced efficacy
  • Novel delivery systems such as dissolvable tablets or patches
  • Reformulations targeting reduced gastrointestinal irritation

MOTRIN’s ability to innovate while maintaining regulatory compliance will be pivotal in sustaining growth.


Financial Trajectory

Revenue Streams and Growth Drivers

Sales Performance:
Historical data indicates consistent growth in OTC NSAID segments, with MOTRIN accounting for a substantial share. The migraine-specific product’s segment revenue depends on factors such as:

  • Market penetration rates
  • Advertising and promotional campaigns
  • Pricing strategies and insurance reimbursement policies

Growth Drivers:

  • Rising migraine prevalence globally
  • Consumer tendency toward OTC solutions
  • Expansion into emerging markets with growing middle-class populations

Pricing and Profitability

Despite intense competition, MOTRIN MIGRAINE PAIN maintains premium positioning through brand loyalty. Price elasticity remains moderate, with some pressure from generics and private-label brands. High-margin formulations and efficient supply chains contribute to profitability.

Market Penetration and Expansion

Emerging markets, including Asia-Pacific and Latin America, present significant growth prospects owing to increasing healthcare infrastructure and awareness. Strategic partnerships and localized marketing initiatives will influence financial outcomes.

Forecasting and Future Outlook

Analysts project a compound annual growth rate (CAGR) of approximately 4-6% for migraine-specific OTC analgesics through 2027. Factors such as increased consumer health consciousness, digital marketing, and product innovation are expected to propel this trajectory. However, regulatory hurdles, patent expirations, and competitive pressures may temper growth.


Challenges and Risks

Regulatory Scrutiny:
Any changes in safety regulations or adverse event reports could lead to marketing restrictions or reformulations, impacting revenue.

Market Saturation:
High brand penetration could lead to diminishing returns, necessitating innovation and differentiation.

Pricing Pressures:
Price wars and increased price sensitivity among consumers, especially in price-sensitive markets, can erode profit margins.

Legal and Patent Risks:
Threats of patent expiration and patent challenges from competitors may lead to generic proliferation, impacting revenue streams.


Strategic Recommendations

  • Invest in research and development for novel delivery mechanisms and combination therapies.
  • Expand geographically in emerging markets with tailored marketing strategies.
  • Enhance digital marketing to increase brand engagement and direct-to-consumer sales.
  • Maintain compliance with evolving regulatory standards to avoid legal pitfalls.
  • Leverage brand loyalty through targeted advertising and consumer education campaigns.

Key Takeaways

  • Growing Global Demand: The rising prevalence of migraines worldwide underpins sustained market growth for MOTRIN MIGRAINE PAIN.
  • Competitive Challenges: Brand loyalty is a differentiator, but increasing competition from generics and new formulations necessitates ongoing innovation.
  • Regulatory Influence: Evolving safety and labeling regulations will shape product development and marketing strategies.
  • Emerging Market Opportunity: Expanding into rapid-growth regions offers substantial revenue potential.
  • Investment in Innovation: Continuous product innovation and consumer engagement are essential to maintain financial trajectory and market relevance.

FAQs

1. How does MOTRIN MIGRAINE PAIN differentiate itself from other migraine OTC medications?
It leverages the MOTRIN brand’s longstanding reputation for safety and efficacy, combined with targeted marketing to migraine sufferers and established OTC availability. Its formulation with ibuprofen provides rapid relief, a key consumer preference.

2. What regulatory factors could impact the future sales of MOTRIN MIGRAINE PAIN?
Changes in OTC drug labeling requirements, safety warnings, or restrictions on ingredients like NSAIDs could affect product formulations, marketing, and sales.

3. How significant is the emerging markets’ contribution to MOTRIN’s financial trajectory?
Very significant. The increasing healthcare infrastructure and rising awareness of migraine treatments in regions like Asia-Pacific and Latin America position emerging markets as primary growth drivers.

4. What role does innovation play in the product’s competitiveness?
Innovation, such as new formulations, delivery systems, and combination therapies, helps differentiate MOTRIN MIGRAINE PAIN amid a crowded OTC market and addresses evolving consumer preferences.

5. What strategic moves can maximize future revenue generation?
Expanding into new markets, investing in product innovation, strengthening digital marketing, and maintaining regulatory compliance are crucial strategies for sustainable growth.


Citations

  1. World Health Organization (WHO). "Migraine Fact Sheet." 2022.
  2. U.S. Food and Drug Administration (FDA). "Over-the-Counter Pain Relievers Guidance." 2021.
  3. IQVIA. "Global Over-the-Counter Analgesics Market Report." 2022.
  4. MarketsandMarkets. "Migraine Drugs Market by Type, Application, and Region." 2023.
  5. Pharmaceutical Technology. "Emerging Innovations in Migraine OTC Treatments." 2022.

This comprehensive analysis equips business professionals with critical insights into the market dynamics and financial trajectory of MOTRIN MIGRAINE PAIN, facilitating strategic decision-making in an evolving landscape.

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