Last Updated: June 17, 2026

MOTRIN IB Drug Patent Profile


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Which patents cover Motrin Ib, and when can generic versions of Motrin Ib launch?

Motrin Ib is a drug marketed by Kenvue Brands and is included in one NDA.

The generic ingredient in MOTRIN IB is ibuprofen. There are sixty-four drug master file entries for this compound. Two hundred and forty-four suppliers are listed for this compound. Additional details are available on the ibuprofen profile page.

DrugPatentWatch® Litigation and Generic Entry Outlook for Motrin Ib

A generic version of MOTRIN IB was approved as ibuprofen by CONTRACT PHARMACAL on October 15th, 1986.

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  • What is the 5 year forecast for MOTRIN IB?
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Summary for MOTRIN IB
US Patents:0
Applicants:1
NDAs:1
Finished Product Suppliers / Packagers: 1
Raw Ingredient (Bulk) Api Vendors: 1
Clinical Trials: 74
Patent Applications: 4,240
What excipients (inactive ingredients) are in MOTRIN IB?MOTRIN IB excipients list
DailyMed Link:MOTRIN IB at DailyMed
Recent Clinical Trials for MOTRIN IB

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
University of MiamiPhase 2
Guangzhou Kangqi Medical Technology Co., LTDPhase 1
Weill Medical College of Cornell UniversityPhase 4

See all MOTRIN IB clinical trials

Pharmacology for MOTRIN IB

US Patents and Regulatory Information for MOTRIN IB

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Kenvue Brands MOTRIN IB ibuprofen TABLET;ORAL 019012-003 Dec 17, 1990 OTC Yes No ⤷  Start Trial ⤷  Start Trial ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

EU/EMA Drug Approvals for MOTRIN IB

Company Drugname Inn Product Number / Indication Status Generic Biosimilar Orphan Marketing Authorisation Marketing Refusal
Recordati Rare Diseases Pedea ibuprofen EMEA/H/C/000549Treatment of a haemodynamically significant patent ductus arteriosus in preterm newborn infants less than 34 weeks of gestational age. Authorised no no no 2004-07-28
>Company >Drugname >Inn >Product Number / Indication >Status >Generic >Biosimilar >Orphan >Marketing Authorisation >Marketing Refusal

MOTRIN IB market dynamics and financial trajectory (OTC ibuprofen, liquid/chewable “IB” formats)

Last updated: June 1, 2026

Motrin IB is an OTC ibuprofen brand in the US, marketed as an ibuprofen product with an “IB” line designation. Public, decision-grade financial visibility typically resides at the segment and brand-mix level rather than on a standalone Motrin IB SKU basis. As a result, the financial trajectory and market dynamics for “Motrin IB” must be framed around (1) the underlying ibuprofen OTC category, (2) the competitive set across OTC NSAIDs, (3) retailer and manufacturer pricing power, and (4) pack-size and formulation mix shifts that change realized net sales for ibuprofen brands.

Key constraints for Motrin IB-specific financials: the Motrin IB designation is frequently referenced in consumer and product labeling, but it is not consistently separated as a distinct, independently reported brand line in large pharma/consumer health financial disclosures. Therefore, “financial trajectory” below is structured around the ibuprofen OTC category economics and observable manufacturer/retailer behavior that drives realized sales and unit movement for OTC NSAIDs generally, with Motrin IB treated as a premiumized ibuprofen brand within that category.


What is Motrin IB and how does it fit into the OTC ibuprofen market?

Motrin IB is a consumer-facing brand for OTC ibuprofen NSAID products in the US. The “IB” line is used for specific Motrin OTC presentations (commonly liquid/chewable formats and related dosing forms across ibuprofen-branded SKUs). The drug substance is ibuprofen, and the therapeutic class is non-steroidal anti-inflammatory drug (NSAID).

OTC ibuprofen market role: what product attributes drive choice?

For consumer OTC NSAIDs, brand choice is driven by:

  • Per-dose value (unit dose price by mg and by dosing frequency)
  • Perceived speed and tolerability (often linked to formulation and dosing form rather than new active substance)
  • Convenience of administration (liquid/chewable vs tablet)
  • Shelf visibility and retailer promotion cadence
  • Availability of store-brand alternatives (private label ibuprofen)

Competitive landscape inside OTC NSAIDs

The competitive set for Motrin IB is not limited to other ibuprofen brands. Consumers compare within the NSAID and broader analgesic OTC space:

  • OTC NSAIDs: other ibuprofen brands and naproxen brands (where applicable by formulation and age indication)
  • OTC analgesics/antipyretics: acetaminophen brands and private label
  • Retail dynamics: planograms and promotions tend to cluster by “pain relief” aisle position, not strictly by active ingredient

How strong are market dynamics for Motrin IB’s ibuprofen OTC category?

Category drivers that typically move OTC ibuprofen brands

OTC ibuprofen category performance is sensitive to:

  • Seasonality: cold and flu season tends to increase demand for OTC analgesics
  • Weather-driven pain patterns: colder months and sports/outdoor activity swings shift usage
  • Trade-down vs trade-up: economic conditions push consumers toward store brands or lower-cost packs
  • Regulatory and safety perception: NSAID GI and cardiovascular risk perceptions influence consumer willingness to pay, even for OTC use
  • Promotion cycles: OTC brands often rely on retailer-funded promotions, multi-buy offers, and endcaps

Price and promotion pressure: where brand economics compress

In OTC ibuprofen, realized net sales and margin are usually constrained by:

  • Frequent promotions that reduce net price
  • Private label competition that sets a price anchor
  • Mix shifts away from higher-priced branded packs to lower-priced pack sizes or channels

For Motrin IB, brand strength depends on whether its “IB” SKU formats maintain premium positioning versus store-brand equivalents and whether retailers continue to allocate shelf and promotions for Motrin IB-specific formats.


What are the main revenue levers for OTC ibuprofen brands like Motrin IB?

1) Pack architecture and dose concentration

Brand realized revenue is driven by changes in:

  • Pack size (counts and number of doses per unit)
  • Dose strength and the share of higher mg-per-bottle equivalents
  • Formulation (liquid vs chewable vs tablets) because consumers value dosing convenience differently

2) Channel mix

OTC analgesics shift across:

  • Mass retail
  • Club stores
  • Pharmacy chains
  • Online/marketplaces with distinct pricing and promotional behavior

Brand performance improves when premium formats maintain share in pharmacy and e-commerce, and deteriorates when club/mass share shifts to private label.

3) Retailer promotion and merchandising

Motrin IB’s brand economics are typically exposed to:

  • Retailer participation rates in promotions
  • Slotting and shelf placement
  • Endcap and featured displays during back-to-school and seasonal peaks

When does Motrin IB lose exclusivity, and does patent timing matter for this product?

For Motrin IB as an OTC ibuprofen brand, “exclusivity” is not the primary determinant of market dynamics in the way it is for prescription biologics and novel drugs. Ibuprofen is a long-established small molecule with extensive generic availability. In practice:

  • OTC availability depends on labeling, formulation, packaging, and brand marketing, not brand-level patent exclusivity.
  • Any remaining IP relevance is typically limited to specific formulations, delivery systems, dosing devices, or method-of-use claims, which matter more for a premium formulation brand than for the underlying active ingredient.

Therefore, “loss of exclusivity” is not the dominant timeline risk for Motrin IB; the more material risk is brand share attrition due to private label and price competition.


What patent estate would be relevant to Motrin IB’s specific OTC formats?

Because Motrin IB is a brand name for ibuprofen, patent estate analysis would focus on:

  • Formulation patents (if any) tied to the “IB” presentation (for example, chewable or liquid technology)
  • Manufacturing process patents
  • Labeling and dosing/regimen patents (method-of-use for specific populations is uncommon for classic OTC ibuprofen, but it can occur for certain OTC claims)

However, absent a defined target list of exact Motrin IB OTC NDCs, a complete and accurate “which patents protect Motrin IB” mapping cannot be produced in a way that is reliable for licensing, litigation, or investment decisions.


What is the Orange Book status of Motrin IB?

Orange Book listings typically cover approved prescription and certain OTC products with active ingredients and specific dosage forms under FDA’s Drug Approval system. For a legacy active ingredient like ibuprofen, many formulations are long since off-patent at the active ingredient level, and the Orange Book status is generally not a constraining factor for market entry at the active ingredient level.

A MOTRIN IB-specific Orange Book table requires mapping from:

  • exact Motrin IB product to NDC(s)
  • the associated FDA application and listed patents Without that product-to-NDC mapping, producing a complete Orange Book status is not decision-grade.

How do generic ibuprofen and private label affect Motrin IB’s financial trajectory?

Financial impact mechanism

OTC ibuprofen brands face a predictable economic sequence:

  1. Entry of store brand or generic creates price ceilings
  2. Promotional intensity increases across the category
  3. Brand premium narrows unless the branded SKU retains differentiation via convenience and pack design

What keeps Motrin IB from fully trading down

Motrin IB can sustain revenue when it:

  • Holds a premium position in convenience formats
  • Maintains strong retail distribution and shelf presence
  • Drives loyalty through recognizable brand equity and perceived product consistency

If retailers reduce promotion or allocate more shelf space to private label, Motrin IB’s net price and unit volumes typically decline.


How does Motrin IB compare with other OTC ibuprofen brands (market share and pricing power)?

In OTC NSAIDs, brand comparison typically hinges on:

  • Net price vs trade-down index
  • Share of shelf and promotion participation
  • Pack size mix and unit dose economics

Motrin IB competes against:

  • Other branded ibuprofen products with similar OTC claims
  • Private label ibuprofen tablets and liquids
  • Cross-class alternatives such as acetaminophen and naproxen OTC products

Without a specified geography (US-wide vs regional) and without defined NDCs, any quantitative market share and pricing-power ranking would not be accurate enough for business decisions. The competitive reality is that pricing power is usually limited and most differentiation is merchandising-led.


What distribution and manufacturing/IP barriers could slow generic or private label competition?

For legacy small molecules like ibuprofen:

  • Manufacturing barriers are usually low once generic processes are validated
  • The main barriers are retailer contracting, brand slotting, and formulation-based differentiation

For Motrin IB specifically, if any “IB” formats use differentiated excipients, chewable matrices, or liquid stabilization systems, those could slow direct look-alike substitution. But the economic barrier is rarely sufficient to prevent private label encroachment in high-velocity OTC categories.


How do OTC NSAID safety signals and consumer perception affect Motrin IB sales?

Safety perception influences:

  • Household purchasing decisions (especially for frequent users)
  • Physician/pharmacist guidance indirectly affecting consumer choices
  • Regulatory labeling changes that can alter risk-benefit framing

Across NSAIDs, such signals can drive modest category mix shifts even if the active ingredient remains available OTC.


What litigation or settlement activity would matter for Motrin IB’s market trajectory?

For Motrin IB as ibuprofen, large prescription-style patent litigation is typically less central than for new drugs. Any material litigation would likely relate to:

  • Specific OTC formulation or manufacturing process claims (if present)
  • Trademark and packaging trade dress (brand protection)
  • FTC/antitrust or retailer promotional disputes (rare, but can move economics)

Without NDC-level product mapping and a defined list of relevant dockets, producing a complete “what litigation affects Motrin IB” record is not decision-grade.


Commercial trajectory: what financial outcomes should investors expect from Motrin IB demand?

Given ibuprofen’s maturity:

  • Top-line growth for Motrin IB is mainly driven by category growth and mix, not by new market creation.
  • Net sales growth typically tracks OTC analgesic cycles and retailer promotion intensity.
  • Margin tends to compress in periods with heavy private label pressure and high trade-down behavior.

For a premium-branded ibuprofen format like Motrin IB, the most realistic financial pattern is:

  • stronger performance during seasonal demand peaks if promoted effectively
  • weaker performance in periods where retailers push private label or consumers downtrade by price

A standalone SKU forecast is not supportable here without NDC-level sales history.


Key Takeaways

  • Motrin IB is an OTC ibuprofen brand; its financial trajectory is driven by OTC NSAID category cycles, retailer promotion economics, and pack/formulation mix rather than patent exclusivity.
  • Market dynamics for branded OTC ibuprofen are structurally exposed to private label and generic pricing pressure, which compresses net price and margin.
  • “Loss of exclusivity” and “patent estate strength” matter far less than shelf presence, convenience-based differentiation, and retailer merchandising for Motrin IB-specific formats.
  • Any decision-grade patent, Orange Book, or litigation view requires exact Motrin IB NDC mapping; without it, a complete and accurate estate cannot be produced.

FAQs

  1. How does OTC ibuprofen demand change during cold and flu season for brands like Motrin IB?
  2. Does private label ibuprofen usually undercut branded Motrin IB on a per-dose basis or via pack-size changes?
  3. What channel mix (mass, club, pharmacy, online) most impacts Motrin IB’s realized net sales?
  4. Are there formulation-specific protections that can delay direct substitution of Motrin IB’s liquid or chewable formats?
  5. How do retailer promotion structures (multi-buy, couponing, endcaps) typically translate into margin swings for OTC NSAID brands?

References

  1. FDA. Orange Book: Approved Drug Products with Therapeutic Equivalence Evaluations. U.S. Food and Drug Administration. https://www.accessdata.fda.gov/scripts/cder/daf/
  2. FDA. OTC Drug Products: Monographs and Regulation of Over-the-Counter Products. U.S. Food and Drug Administration. https://www.fda.gov/drugs/over-counter-drugs

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