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Generated: November 14, 2018

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LEUCOVORIN CALCIUM Drug Profile

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Which patents cover Leucovorin Calcium, and what generic alternatives are available?

Leucovorin Calcium is a drug marketed by Hospira, Abic, Abraxis Pharm, Elkins Sinn, Fresenius Kabi Usa, Pharmachemie, Pharmachemie Usa, Teva Parenteral, Teva Pharms Usa, West-ward Pharms Int, Ani Pharms Inc, Barr, Epic Pharma Llc, Par Pharm, Xanodyne Pharm, Luitpold, Mylan Labs Ltd, and Sagent Pharms. and is included in forty-three NDAs.

The generic ingredient in LEUCOVORIN CALCIUM is leucovorin calcium. There are nine drug master file entries for this compound. Nine suppliers are listed for this compound. Additional details are available on the leucovorin calcium profile page.

Drug patent expirations by year for LEUCOVORIN CALCIUM
Pharmacology for LEUCOVORIN CALCIUM
Medical Subject Heading (MeSH) Categories for LEUCOVORIN CALCIUM
Synonyms for LEUCOVORIN CALCIUM
(+)-L-Folinic acid, calcium salt
(2S)-2-[(4-{[(2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid
(2S)-2-[[4-[(2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
(2S)-2-[[4-[(2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid; calcium; pentahydrate
(4-(((2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzoyl)-L-glutamic acid, calcium salt pentahydrate
(5-formyl-5,6,7,8-tetrahydropteroyl)glutamate
(S)-2-{4-[(2-Amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydro-pteridin-6-ylmethyl)-amino]-benzoylamino}-pentanedioic acid
[3H]folinic acid
10-Formyl-7,8-dihydrofolic acid
121521-95-7
1236362-90-5
1492-18-8
1492-18-8 (anhydrous)
1492-18-8 (calcium (1:1) salt)
17435-36-8
2-{4-[(2-Amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydro-pteridin-6-ylmethyl)-amino]-benzoylamino}-pentanedioic acid
30771-29-0
3102-53-2
33299-78-4
34786-59-9
40244-99-3
42476-21-1 (mono-hydrochloride salt)
492F188
5-Formyl-5,6,7,8-tetrahydrofolic acid
5-Formyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid
5-Formyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid calcium salt
5-Formyl-tetrahydrofolate
5-formyltetrahydro-folic acid
5-formyltetrahydrofolate
5-Formyltetrahydrofolic acid
5-Formyltetrahydropteroylglutamic acid
58-05-9
58-05-9 (Parent)
6035-45-6
6035-45-6 (calcium (1:1) salt, penta-hydrate)
6209-45-6
641-41-8
80433-71-2
AC-13429
AC-24016
AC-7456
AC1L1LLF
AC1L259Q
AC1L9FEF
AC1O3RNF
Acide folinique
AKOS015894859
AKOS015961207
AKOS026749804
AKOS032949578
AN-49327
AN-9009
AOB5605
AS-13746
BC206228
BDBM50039121
BIC0607
BPBio1_000766
BRD-A75919782-238-01-8
BSPBio_000696
BSPBio_002218
C20H21CaN7O7
C20H21N7O7.Ca
Calcii folinas
Calcii folinas [INN-Latin]
calcium (2S)-2-[[4-[(2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioate
Calcium 5-formyltetrahydrofolate
Calcium citrovorum factor
Calcium folinatc
calcium folinate
Calcium folinate (JP17)
Calcium folinate [INN]
Calcium folinate, 98% 250mg
Calcium Folinate, USP
Calcium folinate(Leucovorin Calcium)
Calcium L-folinate
Calcium leucovorin
Calcium N-(p-((((6RS)-2-amino-5-formyl-5,6,7,8-tetrahydro-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamate (1:1)
calcium;(2S)-2-[[4-[(2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioate
Calciumlevofolinate
CCG-38930
CHEBI:15640
CHEBI:31340
CHEMBL1201138
CHEMBL1679
CHEMBL69905
Citrovoeum factor
CS-1363
CS-2989
D01211
D0B6TW
D0R4PS
DB00650
DivK1c_000222
DTXSID0048216
DTXSID20872448
DW385
EINECS 200-361-6
EINECS 216-082-8
F-7000
Folidan
folinate
Folinate de calcium
Folinate de calcium [INN-French]
Folinate-SF Calcium
Folinato calcico
Folinato calcico [INN-Spanish]
folinic acid
Folinic acid (Calcium)
folinic acid calcium
Folinic acid calcium salt
Folinic acid calcium salt hydrate
Folinic acid-SF
Folinic acid-SF, calcium salt
FT-0083577
FT-0603241
FT-0603561
FT-0654951
Glutamic acid, N-(p-(((2-amino-5-formyl-5,6,7,8-tetrahydro-3-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-, calcium salt (1:1), L-
Glutamic acid, N-(p-(((2-amino-5-formyl-5,6,7,8-tetrahydro-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-, L-
GTPL4816
GTPL6690
HE313049
HE355777
HMS1570C18
HMS1920J05
HMS2091P21
HMS2097C18
HMS500L04
HSDB 6544
HY-13664
HY-17556
I06-116
IDI1_000222
J10233
KBio1_000222
KBio2_001339
KBio2_003907
KBio2_006475
KBio3_001438
KBioGR_000461
KBioSS_001339
KVUAALJSMIVURS-ZEDZUCNESA-L
L-(+)-Folinic acid
L-Glutamic acid, N-(4-(((2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-
L-Glutamic acid, N-(4-(((2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-, calcium salt (1:1)
L-Glutamic acid, N-[4-[[(2-amino-5-formyl-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-
l-Leucovorin
L(-)-5-Formyl-5,6,7,8-tetrahydrofolic acid
Lederfoline
Leucal
Leucoverin
leucovorin
Leucovorin [USAN]
Leucovorin calcium (USP)
Leucovorin Calcium [USAN]
Leucovorin calcium [USP]
Leucovorin calcium preservative free
Leucovorin calcium salt
Leucovorinum
Leucovorinum (acid)
Levocovorin
LEVOLEUCOVORIN CALCIUM
LS-71774
MFCD00149463
MolPort-003-666-218
MolPort-004-964-288
N-(5-formyl-5,6,7,8-tetrahydropteroyl)-L-glutamic acid
N-[4-({[2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid
N-[4-[[(2-Amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6(RS)-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
N5-Formyl-5,6,7,8-tetrahydrofolic acid
N5-Formyltetrahydrofolic acid
NINDS_000222
NSC 3590
NSC3590
Prestwick_224
Prestwick0_000738
Prestwick1_000738
Prestwick2_000738
Prestwick3_000738
Rescuvolin
RL01892
SBI-0051427.P003
SCHEMBL10068238
SCHEMBL18573
SCHEMBL8349
SD-204098
Sodium folinate
SPBio_000132
SPBio_002635
Spectrum_000859
SPECTRUM1500364
Spectrum2_000116
Spectrum3_000479
Spectrum4_000031
Spectrum5_000910
ST51016071
Uzel (TN)
V3415
VVIAGPKUTFNRDU-ABLWVSNPSA-N
Welcovorin
Wellcovorin
Wellcovorin (TN)
X5041

US Patents and Regulatory Information for LEUCOVORIN CALCIUM

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Mylan Labs Ltd LEUCOVORIN CALCIUM PRESERVATIVE FREE leucovorin calcium INJECTABLE;INJECTION 203800-001 May 19, 2017 AP RX No No ➤ Sign Up ➤ Sign Up ➤ Sign Up
West-ward Pharms Int LEUCOVORIN CALCIUM leucovorin calcium TABLET;ORAL 072735-001 Feb 22, 1993 RX No No ➤ Sign Up ➤ Sign Up ➤ Sign Up
Teva Parenteral LEUCOVORIN CALCIUM PRESERVATIVE FREE leucovorin calcium INJECTABLE;INJECTION 040332-001 Jun 28, 1999 DISCN No No ➤ Sign Up ➤ Sign Up ➤ Sign Up
Sagent Pharms LEUCOVORIN CALCIUM PRESERVATIVE FREE leucovorin calcium INJECTABLE;INJECTION 200753-002 Sep 6, 2012 AP RX No No ➤ Sign Up ➤ Sign Up ➤ Sign Up
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Colorcon
Mallinckrodt
Merck
Express Scripts
Harvard Business School
Chinese Patent Office
Fuji
Deloitte
Medtronic

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.