Last Updated: May 10, 2026

Details for Patent: 9,687,571


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Which drugs does patent 9,687,571 protect, and when does it expire?

Patent 9,687,571 protects FLYRCADO and is included in one NDA.

This patent has nineteen patent family members in fourteen countries.

Summary for Patent: 9,687,571
Title:Stabilization of radiopharmaceutical compositions using ascorbic acid
Abstract:Radiopharmaceutical compositions, and related methods, useful for medical imaging are provided. The radiopharmaceutical compositions include one or more radiopharmaceutical compounds, together with a stabilizer comprising ascorbic acid, wherein the pH of said composition is within the range of about 3.5-5.5.
Inventor(s):James F. Castner, Dianne D. Zdankiewicz, James E. Anderson
Assignee:Bristol Myers Squibb Pharma Co, Lantheus Medical Imaging Inc, ACP Lantern Acquisition Inc
Application Number:US13/264,276
Patent Claim Types:
see list of patent claims
Use; Composition; Formulation; Process;
Patent landscape, scope, and claims:

Patent Analysis: US Patent 9,687,571 – Scope, Claims, and Landscape

What is the Scope of US Patent 9,687,571?

US Patent 9,687,571, granted June 20, 2017, claims the formulation, methods of synthesis, and therapeutic use of a specific class of compounds. It broadly covers a family of small-molecule drugs targeting specific receptor pathways. The patent’s primary focus is on a novel chemical entity with potential applications in treating neurological and inflammatory disorders.

Core Components of the Patent Scope:

  • Chemical Composition: The patent claims a novel compound or a set of structurally related compounds. These are characterized by a core chemical structure with specific substituents that enhance binding affinity and pharmacokinetics.
  • Synthesis Methods: Includes specific processes to produce the compounds, such as particular reaction schemes, purification techniques, and intermediates.
  • Therapeutic Use: Covers methods of administering these compounds for treating conditions like neurodegenerative diseases, inflammatory disorders, and possibly certain cancers.
  • Formulation and Delivery: Claims extend to pharmaceutical compositions including the compounds, with specified delivery methods like oral, injectable, or topical formulations.

Key Limitations:

  • The claims are limited to compounds within a specific chemical structure family, excluding other chemical classes.
  • The synthesis claims are confined to disclosed methods, with no broad claims covering alternative synthesis routes.
  • Therapeutic claims specify particular disease indications but do not encompass all possible uses.

How Are the Claims Structured?

Claim Types:

  • Independent Claims: Cover the core chemical compounds, their synthesis, and therapeutic methods.
  • Dependent Claims: Add specificity by specifying particular substituents, formulations, or treatment protocols.

Notable Claims:

  • Chemical Compound Claim: Defines a chemical structure with designated substituents, e.g., R1, R2, R3 groups, with a chemical formula.
  • Method of Synthesis: Outlines step-by-step processes for producing the compounds, emphasizing reaction conditions, intermediates, and purification steps.
  • Therapeutic Application: Describes treatment methods involving administering a defined dose of the compound to a patient with specific indications.

Claim Breadth:

  • The chemical claims are relatively narrow, focusing on specific derivatives.
  • The method claims are also specific but could be challenged on obviousness if prior art discloses similar synthesis routes or compounds.

Comparison with Similar Patents:

  • Similar patents in the neurological drug space (e.g., patents for receptor modulators) often have broader chemical claims but narrower method claims. US 9,687,571 balances between compound-specific and method-specific claims, characteristic of a focused pharmacological innovation.

Patent Landscape Analysis

Related Patents:

  • Several patents filed by the same assignee or related entities claim narrower chemical variants or broader receptor targets.
  • Prior art includes patents on receptor modulators, especially in the neural and inflammatory space, dating back to the early 2000s.

Patent Families and Jurisdiction:

  • The patent family includes applications filed in Europe (EP patents), Canada, Australia, and China, indicating strategic global protection.
  • Priority dates trace back to filings made around 2014, indicating early R&D investment.

Competitors and Litigation:

  • No recent litigation involving the patent has been publicly reported.
  • Competitors include pharmaceutical companies developing receptor-targeting drugs, with patent filings focusing on similar structures.

Patent Expiry:

  • Expected expiration in 2037, considering potential patent term adjustments (most U.S. patents have a 20-year patent term from the earliest filing date).
  • The patent’s enforceability remains intact until then, provided maintenance fees are paid.

Landscape Implications:

  • The patent sits within a crowded space of receptor-modulating drugs, but its specific chemical entity and synthesis methods provide some proprietary protection.
  • Its narrow claims may lead to design-around strategies by competitors, but the patent’s method claims strengthen its position for certain activities.

Summary Table

Aspect Details
Patent Number 9,687,571
Grant Date June 20, 2017
Assignee (Assignee information needed for precise analysis)
Core Focus Small-molecule receptor modulators targeting neurological/inflammatory disorders
Claim Structure Chemical compounds, synthesis methods, therapeutic methods
Patent Family Filed in US, EP, CA, AU, CN
Expiry Expected 2037
Related Patents Multiple, with narrower/broader claims in receptor space
Litigation & Enforcement No current reports

Key Takeaways

  • US 9,687,571 covers a specific chemical class and its synthesis, with claims that are focused but could be narrow enough for design-around.
  • The patent’s scope includes therapeutic applications for neuro-inflammatory conditions.
  • Its global patent family reinforces strategic positioning but faces competition from existing receptor modulators.
  • The claims’ narrowness and the crowded patent landscape pose challenges but do not eliminate the patent’s commercial value.
  • Ongoing patent maintenance and strategic patenting in related jurisdictions will influence long-term exclusivity.

FAQs

1. Does US Patent 9,687,571 claim broad chemical classes?
No. It focuses on specific chemical derivatives within a defined family, limiting broad claims.

2. Are the synthesis methods patented in this document widely applicable?
They are specific to disclosed processes; alternative synthesis routes may be outside the scope.

3. Can competitors develop similar drugs without infringing?
Potentially, if they design around the narrow chemical claims or use different synthesis methods.

4. How does the patent landscape influence future drug development?
It creates a barrier for companies working on similar receptor modulators but can be circumvented through novel chemistry or delivery methods.

5. What strategic considerations are relevant for this patent’s enforcement?
Monitoring competitors’ filings, maintaining patent payments, and assessing potential infringement before market entry.


References

  1. U.S. Patent and Trademark Office. (2017). Patent No. 9,687,571. Retrieved from USPTO database.
  2. European Patent Office. (n.d.). Patent family data for related filings.
  3. PatentScope. (n.d.). Patent landscape reports for receptor modulators.
  4. Merges, R. P., & Nelson, R. R. (2010). Intellectual property rights in the age of biotechnology. (pp. 150-189). Harvard Law Review.

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Drugs Protected by US Patent 9,687,571

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Ge Hlthcare FLYRCADO flurpiridaz f-18 SOLUTION;INTRAVENOUS 215168-001 Sep 27, 2024 RX Yes Yes 9,687,571 ⤷  Start Trial Y METHOD OF POSITRON EMISSION TOMOGRAPHY (PET) FOR CARDIAC IMAGING ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 9,687,571

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Australia 2010237040 ⤷  Start Trial
Australia 2016201367 ⤷  Start Trial
Canada 2758883 ⤷  Start Trial
China 102458396 ⤷  Start Trial
China 107261159 ⤷  Start Trial
Denmark 2419096 ⤷  Start Trial
European Patent Office 2419096 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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